Metadata GeoPortal: Advancing Map Data Management and Collaboration Across Sectors by S. Yalcin, M. T. Sert, B. Erkek, E. Ayyildiz

“…Looking ahead, the upcoming “Phase 4” updates will expand the platform’s functionalities, enhancing geospatial data management and collaboration across sectors. …”
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Environmental burden of disease resulting from long-term nitrogen dioxide exposure in Germany by Paulina Sell, Dietrich Plass, Sarah Kienzler, Hajo Zeeb

“…We first conducted a systematic literature review to identify exposure–response functions (ERFs) which mathematically represent the association between NO2 exposure and the health outcomes: asthma, chronic obstructive pulmonary disease (COPD), type 2 diabetes mellitus (T2DM), ischemic heart disease, lung cancer, stroke, and cardiovascular and respiratory mortality. …”
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A novel pulse-current waveform circuit for low-energy consumption and low-noise transcranial magnetic stimulation by Xinhua Tan, Ao Guo, Jiasheng Tian, Yingwei Li, Yingwei Li, Jian Shi

“…Next, the pulse-current waveform was modeled based on the principles of programmable transcranial magnetic stimulation circuits. …”
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Avicularin Treatment Ameliorates Ischemic Stroke Damage by Regulating Microglia Polarization and its Exosomes via the NLRP3 Pathway by Yan Shi, Yufeng Yang, Juntong Liu, Jinling Zheng

“…Modified neurological severity score, Triphenyltetrazolium chloride (TTC) staining, brain-water-content detection, TdT-mediated dUTP nick-end labeling (TUNEL) assay, flow cytometry, immunofluorescence assay, Enzyme linked immunosorbent assay (ELISA), and Western-blot analysis were used to investigate the functions and mechanism of the effect of AL treatment on IS. …”
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Reduced Inter-Element Interference mmWave MIMO Antenna and Its Application in WBAN by Jawad Ahmad, Mohammad Hashmi

“…The combination of high isolation, dual-band functionality, broadside radiation, excellent diversity performance, and acceptable link margin validates the suitability of the proposed MIMO antenna for WBAN communication applications.…”
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Analyses and Forecasting of Smart Grid Technological Dynamics by I. V. Danilin, I. A. Tikhomirov, D. A. Deviatkin

“…A new growth period (with less impressive growth pace) and appearance of new generations of technology would become possible in 2020s after development of new business models, monetization schemes and better alignment of Smart Grid technologies and functionality to stakeholders` interests, values and society requirements. …”
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AGC of a Multi‐Area Hydrothermal Interconnected Diverse Deregulated Power System Using a Proposed Novel SBOA‐Multi‐Level Fuzzy Logic‐Tilt Controller Incorporated With IPFC by Getaneh Mesfin Meseret, Nishant Kumar, Tarkesh Kumar Mahato, Rajesh Kumhar, Poonam Lakra, M. D. Mofeed Alam

“…A significant drop in frequency can negatively affect electric clock synchronization, magnetizing currents in transformers and induction motors, the consistent speed of AC motors, the ongoing operation of processes, and the coordinated functioning of various components within the power system. …”
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Longitudinal association between e-cigarette use and respiratory symptoms among US adults: Findings from the Population Assessment of Tobacco and Health Study Waves 4-5. by Emma Karey, Shu Xu, Pan He, Raymond S Niaura, Charles M Cleland, Elizabeth R Stevens, Scott E Sherman, Omar El-Shahawy, Jennifer Cantrell, Nan Jiang

“…Outcome was a validated index of functionally important respiratory symptoms based on 7 wheezing/cough questions (range 0-9). …”
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Developing an Evidence- and Theory-Informed Mother-Daughter mHealth Intervention Prototype Targeting Physical Activity in Preteen Girls of Low Socioeconomic Position: Multiphase Co... by Carol Brennan, Grainne ODonoghue, Alison Keogh, Ryan E Rhodes, James Matthews

“…These were to be targeted by 6 intervention functions (eg, education, persuasion, and modeling) and 27 behavior change techniques (eg, goal setting and self-monitoring). …”
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Disruption of tumor-intrinsic PGAM5 increases anti-PD-1 efficacy through the CCL2 signaling pathway by Yan Li, Hong Wang, Xiaoyang Li, Yuan He, Huiquan Liu, Dong Han, Ting Mei, Yixuan Li, Zilong Xu, Xiaoying Wei, Jianguo Wang, Peijie Zhou, Yuwen Wang, Ziye Li, Junhao Ning, Anlin Wang, Jingjing Cheng, Dong Qian

“…Macrophages were depleted to investigate whether the effects of tumor-intrinsic PGAM5 on TAMs could affect immunotherapy efficacy in HCC orthotopic and subcutaneous mouse models.Results PGAM5 expression in tumor was positively correlated with M2-phenotype TAM infiltration in patients with both HCC and mouse HCC tumor models. …”
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Androgen receptor inhibition sensitizes glioblastoma stem cells to temozolomide by the miR-1/miR-26a-1/miR-487b signature mediated WT1 and FOXA1 silencing by Ana Belén Díaz Méndez, Marta Di Giuliani, Andrea Sacconi, Elisa Tremante, Valentina Lulli, Marta Di Martile, Giulia Vari, Francesca De Bacco, Carla Boccaccio, Giulia Regazzo, Maria Giulia Rizzo

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Selective arm-usage of pre-miR-1307 dysregulates angiogenesis and affects breast cancer aggressiveness by Oyku Ece Sumer, Korbinian Schelzig, Janine Jung, Xiaoya Li, Janina Moros, Luisa Schwarzmüller, Ezgi Sen, Sabine Karolus, Angelika Wörner, Verônica Rodrigues de Melo Costa, Nishanth Belugali Nataraj, Efstathios-Iason Vlachavas, Clarissa Gerhäuser, Karin Müller-Decker, Dominic Helm, Yosef Yarden, Birgitta Elisabeth Michels, Cindy Körner

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The protective role and mechanism of ginkgolide B in regulating mTOR signalling pathway involved in Manganese-induced apoptosis and autophagy in N27 cells by Liyu Su, Shunyu Xiang, Huan Mao, Jiayu Fu, Hongwei Ding, Feng Wang, Lan Zhao, Jianwei Bai, Yuyan Cen, Deyu Zhu, Meng Deng, Yan Li

“…Ginkgolide B (GB) is a diterpenoid compound found in the leaves of the traditional Chinese medicine plant Ginkgo biloba, which has been shown to have a variety of pharmacological functions. However, the role of GB in Manganese(Mn)-induced apoptosis and autophagy in neuronal cells remains poorly understood. …”
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Efficacy and safety of home-based transcranial direct current stimulation as adjunct treatment for cognitive improvement in major depressive disorder: A double-blind, randomized, m... by CW Lee, K Park, JE Ahn, Y Jang, YS Park, H Yu, D Lee, HK Ihm, J Lee, J Kim, YI Lee, S-E Lim, SS Kwon, HY Park, TH Ha, I-Y Yoon, Woojae Myung, Ji Hyun Baek

“…Linear mixed-effects models examined the interaction of group and time. …”
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Unlocking liver physiology: comprehensive pathway maps for mechanistic understanding by Luiz Ladeira, Anouk Verhoeven, Jonas van Ertvelde, Jian Jiang, Alessio Gamba, Julen Sanz-Serrano, Tamara Vanhaecke, Harm J. Heusinkveld, Ramiro Jover, Mathieu Vinken, Liesbet Geris, Liesbet Geris, Liesbet Geris, Bernard Staumont

“…In this study, we introduce two Liver Physiological Maps (PMs); comprehensive and machine-readable graphical representations of the intricate mechanisms governing two major liver functions.MethodsTwo PMs were developed through manual literature curation, integrating data from established pathway resources and domain expert knowledge. …”
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The role of gut microbiota in a generalist, golden snub-nosed monkey, adaptation to geographical diet change by Yuhang Li, Yujie Yan, Haojie Wu, Yiyi Men, Yi Yang, Hengguang Fu, Derek Dunn, Xiaowei Wang, Genggeng Gao, Peng Zhang, Guixin Dong, Liyuan Hao, Jia Jia, Baoguo Li, Songtao Guo

“…The impact of temporal dietary shifts on gut microbiota has been elucidated through multidimensional modeling of both food component and macronutrient intake. …”
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Clinical Predictors of Cognitive Impairment in a Cohort of Patients with Older Age Bipolar Disorder by Camilla Elefante, Giulio Emilio Brancati, Maria Francesca Beatino, Benedetta Francesca Nerli, Giulia D’Alessandro, Chiara Fustini, Daniela Marro, Gabriele Pistolesi, Filippo Baldacci, Roberto Ceravolo, Lorenzo Lattanzi

“…Univariate comparisons and multivariate logistic regression models were performed to investigate the associations between clinical variables and cognitive impairment. …”
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Family-focused intervention programme to foster adolescent mental health and well-being: protocol for a multicountry cluster randomised factorial trial (FLOURISH Phase 2) by Heather M Foran, Marija Raleva, Nina Heinrichs, Graham Moore, Yulia Shenderovich, Xiang Zhao, Judith Simon, Antonio Piolanti, Viorel Babii, Janina Mueller, Franziska Waller, Dennis Wienand, Swetha Sampathkumar, Ivo Kunovski

“…Primary outcomes will include adolescent internalising problems and social support, family functioning and attendance during the programme. Secondary outcomes will assess broader aspects of mental health among caregivers and adolescents, as well as implementation and cost outcomes. …”
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Understanding Stellar Mass–Metallicity and Size Relations in Simulated Ultrafaint Dwarf Galaxies by Minsung Go, Myoungwon Jeon, Yumi Choi, Nitya Kallivayalil, Sangmo Tony Sohn, Gurtina Besla, Hannah Richstein, Sal Wanying Fu, Tae Bong Jeong, Jihye Shin

“…The metallicity distribution functions (MDFs) of our simulated UFDs lack high-metallicity stars ([Fe/H]≥ −2.0) while containing low-metallicity stars ([Fe/H] < −4.0). …”
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Intracellular HIV-1 Tat regulator induces epigenetic changes in the DNA methylation landscape by Andrea Rodríguez-Agustín, Andrea Rodríguez-Agustín, Rubén Ayala-Suárez, Francisco Díez-Fuertes, Francisco Díez-Fuertes, María José Maleno, Izar de Villasante, Angelika Merkel, Mayte Coiras, Mayte Coiras, Víctor Casanova, Víctor Casanova, José Alcamí, José Alcamí, José Alcamí, José Alcamí, Núria Climent, Núria Climent, Núria Climent

“…IntroductionThe HIV regulatory protein Tat enhances viral transcription and also modifies host gene expression, affecting cell functions like cell cycle and apoptosis. Residual expression of Tat protein is detected in blood and other tissues even under antiretroviral treatment. …”
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