Periplocin potentiates ferroptotic cell death in non-small cell lung cancer by inducing the degradation of Nrf2 by Jinhao Wang, Yue Zhu, Jialiang Song, Fengping Yang, Peng Wang, Ziyi Zhang, Yuxuan Li, Minghe Dai, Yinuo Wang, Waleed Yousuf, Jiayu Li, Dian Yang, Shaoxuan Cheng, Shuyan Liu, Zhaoxia Dai, Xun Qiu, Yingqiu Zhang, Zengchun Hu

“…The in vivo effects of periplocin were assessed using lung cancer xenograft mouse models. Results Periplocin inhibited lung cancer cell growth in vitro. …”
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Disentangling the effects of eutrophication and natural variability on macrobenthic communities across French coastal lagoons by Jones, Auriane G., Schaal, Gauthier, Boyé, Aurélien, Creemers, Marie, Derolez, Valérie, Desroy, Nicolas, Fiandrino, Annie, Mouton, Théophile L., Simier, Monique, Smith, Niamh, Ouisse, Vincent

“…Owing to their position at the interface between land and sea, they are also subject to increasing human impacts, which alter their ecological functioning. Because coastal lagoons are naturally highly variable in their environmental conditions, disentangling the effects of anthropogenic disturbances like eutrophication from those of natural variability is a challenging, yet necessary issue to address. …”
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The Application of Variable Weight Theory on the Suitability Evaluation of Urban Underground Space Development and Utilization for Urban Resilience and Sustainability by Hongnian Chen, Xianfeng Tan, Yan Zhang, Bo Hu, Shuming Xu, Zhenfen Dai, Zhengxuan Zhang, Hanxiang Xiong, Xiaoqing Song, Danyuan Luo

“…We strongly recommend that this framework be highly promoted in future research and strongly encourage future studies to place greater emphasis on the ultimate goal of achieving the SDGs by 2030 during updates to models, variable weight functions, factors, and frameworks.…”
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The dynamics of lowland river sections of Danube and Tisza in the Carpathian basin by Imre M. Jánosi, Imre M. Jánosi, István Zsuffa, István Zsuffa, Tibor Bíró, Boglárka O. Lakatos, Boglárka O. Lakatos, András Szöllősi-Nagy, Zsolt Hetesi, Zsolt Hetesi

“…The empirical histograms for half-daily water level changes can be well-fitted by piecewise-exponential functions containing four or three sections, consistent with the understanding that level changes are deterministic rather than stochastic processes, as is well known in hydrology. …”
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Beyond the closed-forest paradigm: Cross-scale vegetation structure in temperate Europe before the late-Quaternary megafauna extinctions by Elena A. Pearce, Florence Mazier, Charles W. Davison, Oliver Baines, Szymon Czyżewski, Ralph Fyfe, Krzysztof Bińka, Steve Boreham, Jacques-Louis de Beaulieu, Cunhai Gao, Wojciech Granoszewski, Anna Hrynowiecka, Małgorzata Malkiewicz, Tim Mighall, Bożena Noryśkiewicz, Irena Agnieszka Pidek, Jaqueline Strahl, Hanna Winter, Jens-Christian Svenning

“…Using LOVE (Local Vegetation Estimates) and REVEALS (Regional Estimates of VEgetation Abundance from Large Sites) models, this study reconstructs vegetation patterns across local (∼9 km²) and regional (∼100 km²) scales. …”
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Loss of TACC2 impairs chemokine CCL3 and CCL4 expression and reduces response to anti-PD-1 therapy in soft tissue sarcoma by Jing Yang, Xiuxia Lu, Qiyan Cai, Mengmeng Liu, Tianliang Xia, Dongchun Hong, Liyuan Le, Xinke Zhang, Xing Zhang

“…Conclusions In conclusion, TACC2 is an important regulator of the immune response in STS, functioning as a tumor suppressor and a modulator of response to PD-1 blockade. …”
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Autoantibodies Targeting Vinculin Reveal Novel Insight into the Mechanisms of Autoimmune Podocytopathies by Hanyan Meng, Dongjie Wang, Chen Zheng, Chao Zhou, Xinrui Mao, Jinglan Gu, Xiaohui Qiao, Fei Liu, Jingjing Wang, Haidong Fu, Jianhua Mao, Qing Ye

“…Immune-mediated mouse models were established to verify the pathogenicity of anti-vinculin autoantibodies. …”
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Nutrient availability modulates the effects of plastic leachates on the growth and community dynamics of free-living freshwater bacteria by Marius Schubert, Fazel Abdolahpur Monikh, Fazel Abdolahpur Monikh, Fazel Abdolahpur Monikh, Yuyi Yang, Yuyi Yang, Yuyi Yang, Hans-Peter Grossart, Hans-Peter Grossart

“…Our findings reveal that synthetic polymer pollution has the potential to alter microbial loop functioning and hence biochemical cycles of aquatic ecosystems.…”
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Proactive and reactive movement behaviours shape the antipredator sequence in a large herbivore by Charlotte Vanderlocht, Benjamin Robira, Andrea Corradini, Simone Dal Farra, Federico Ossi, Davide Righetti, Heidi C. Hauffe, Luca Pedrotti, Francesca Cagnacci

“…Using an exhaustive inventory of red deer hunting events and very high-resolution canopy cover density (LiDAR), we combined movement metric (displacement and path length) models and integrated step selection functions to investigate antipredator movement responses to lethal risk on various spatiotemporal scales, considering a dynamic landscape of risk. …”
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Implementation of the Symptom Navi © Programme for cancer patients in the Swiss outpatient setting: a study protocol for a cluster randomised pilot study (Symptom Navi© Pilot Study... by Marika Bana, Karin Ribi, Susanne Kropf-Staub, Sabin Zürcher-Florin, Ernst Näf, Tanja Manser, Lukas Bütikofer, Solange Peters, Manuela Eicher

“…Outcomes include patients’ accrual and retention rates, patient-reported interference of symptoms with daily functions, symptom burden, perceived self-efficacy, quality of nursing care, nurse-reported facilitators and barriers of adopting the programme, nurses’ fidelity of providing the intervention as intended, and patients’ safety (patients timely reporting of severe symptoms). …”
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Semantic distances of WAIS Similarities word pairs in non-demented adults: An item-level index of semantic memory granularity by Matteo De Marco, Satyam Chauhan, Martina Bocchetta, Annalena Venneri

“…Six hundred sixty-nine non-demented participants completed a neuropsychological battery inclusive of SIM and consolidated tests of semantic memory and executive functioning. Hierarchical linear regressions were designed to test the association between LCH and semantic memory performance after controlling for major confounders. …”
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Maternal consumption of a fermented diet protects offspring against intestinal inflammation by regulating the gut microbiota by Cheng Wang, Siyu Wei, Bojing Liu, Fengqin Wang, Zeqing Lu, Mingliang Jin, Yizhen Wang

“…In addition, the MFD significantly accelerated the maturation of the gut microbiota of neonates and increased the abundance of gut Lactobacillus and the microbial functions of amino acid-related enzymes and glucose metabolism on the weaning day. …”
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A novel strategy to optimize resources to boost production in rice-fish coculture at Ziro Valley, India by Ayan Samaddar, Dani Kacha, Anilava Kaviraj, Sarah Freed, Arun Panemangalore Padiyar, Sambhu Das, Subrata Saha

“…Using Cobb-Douglas production functions, researchers estimated rice and fish yields through regression models. …”
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High nitrate and sulfate leaching in response to wetter winters in temperate beech forests by Aron Garthen, Jan Philip Berg, Eva Ehrnsten, Marcin Klisz, Robert Weigel, Lisa Wilke, Jürgen Kreyling

“…We investigated the effects of increased winter rainfall on the ecosystem functioning of European beech forests at their north-eastern distribution range. …”
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Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study. by Darren M Lipnicki, John D Crawford, Rajib Dutta, Anbupalam Thalamuthu, Nicole A Kochan, Gavin Andrews, M Fernanda Lima-Costa, Erico Castro-Costa, Carol Brayne, Fiona E Matthews, Blossom C M Stephan, Richard B Lipton, Mindy J Katz, Karen Ritchie, Jacqueline Scali, Marie-Laure Ancelin, Nikolaos Scarmeas, Mary Yannakoulia, Efthimios Dardiotis, Linda C W Lam, Candy H Y Wong, Ada W T Fung, Antonio Guaita, Roberta Vaccaro, Annalisa Davin, Ki Woong Kim, Ji Won Han, Tae Hui Kim, Kaarin J Anstey, Nicolas Cherbuin, Peter Butterworth, Marcia Scazufca, Shuzo Kumagai, Sanmei Chen, Kenji Narazaki, Tze Pin Ng, Qi Gao, Simone Reppermund, Henry Brodaty, Antonio Lobo, Raúl Lopez-Anton, Javier Santabárbara, Perminder S Sachdev, Cohort Studies of Memory in an International Consortium (COSMIC)

“…We analyzed standardized Mini-Mental State Examination (MMSE) and memory, processing speed, language, and executive functioning test scores using linear mixed models, adjusted for sex and education, and meta-analytic techniques. …”
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Development of an Automated Aquarium Monitoring System with an IoT Interface using Google Sheets by Theodore Tochuckwu Chiagunye, Somtochukwu Francis Ilo, Godspower Ikechukwu Ndukwe, Henrietta Uchenna Udeani, Ogobuchi Daniel Okey

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Research on underground coal gasification from 2023 to 2024: A systematic review by Yong QIN, Tongsheng YI, Lingxia WANG

“…Research on the production dynamics and process control of UCG has expanded, refining heat and mass transfer models, as well as relevant simulation methodologies, and establishing mathematical models for key parameters governing UCG cavity growth. …”
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Magnitude of antigen-specific T-cell immunity the month after completing vaccination series predicts the development of long-term persistence of antitumor immune response by Mary L Disis, John B Liao, Jessica L Reichow, Lupe G Salazar, Sasha E Stanton, Katie M Hitchcock-Bernhardt, James Y Dai, Jong-Baeck Lim, Theodore A Gooley

“…The baseline and 1-month post-vaccine series responses were correlated with immunity at long-term follow-up by logistic regression. Immunity was modeled by non-linear functions using generalized additive models.Results Antigen-specific T-cell responses at baseline were associated with a 0.33-log increase in response at long-term follow-up, 95% CI (0.11, 0.54), p=0.003. 63% of patients that had HER2/neu specific T cells at baseline continued to have responses at long-term follow-up. …”
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First principles investigation of bandgap modulation and light matter interaction in cubic X₂ScInI₆ halide double perovskites for emerging energy applications by Muhammad Yar Khan, Muhammad Awais Jehangir, It Ee Lee, Qamar Wali, Tariq Usman, Li Xiaojie, Abdullah Al Souwaileh

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Software and Hardware Control System for Implementing the Balance Error Scoring System by Oksana Blavt, Gennadii Iedynak, Lesia Galamanzhuk, Tetyana Helzhynska, Yurii Kachurak, Yulia Mykhalskа, Liubov Levandovska, Rostyslav Tymkovych

“…The findings indicate that the use of advanced technologies and dependable automated control systems in inclusive physical education for the collection, careful study and analysis of test data ensures the generation of high-quality, trustworthyinformation, which serves as the basis for creating reliable and scientifically sound programs for restoring damaged functions after blast TBI. …”
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