Integrating metagenomics and metabolomics to study the gut microbiome and host relationships in sports across different energy systems by Viviana Aya, Daniel Pardo-Rodriguez, Laura Camila Vega, Mónica P. Cala, Juan David Ramírez

“…In athletes, these microbial functions may be further specialized to meet the unique metabolic demands of different sports disciplines. …”
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Magnetic Thomson Transport in High-opacity Domains by Matthew G. Baring, Kun Hu, Hoa Dinh Thi

“…Empirical approximations for these parameters as functions of the ratio of the photon and cyclotron frequencies are presented. …”
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Modulating inflammatory prostaglandin E2 signaling to mitigate neurobehavioral comorbidities associated with seizure disorders by Chenyao Jiang, Ying Yu, Jiawang Liu, Jianxiong Jiang

“…Although epilepsy is first known as a disease of seizures and convulsions, most patients with epilepsy also suffer from seizure-associated behavioral abnormalities in motor functions, psychiatric status, and cognition. These neurobehavioral comorbidities may have greater impacts on the quality of life of people with epilepsy than the seizures themselves and can profoundly interfere with the treatment compliance. …”
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Acoustic, aerodynamic, and vibrational effects of ventricular folds adduction in an ex vivo experiment by Zhixue Xiao, Jing Kang, Jinglin Su, Pingjiang Ge, Siyi Zhang

“…The aperiodic and irregular vibration of the ventricular folds may be responsible for this phenomenon, although further experiments are warranted. Understanding the functioning of ventricular folds can be beneficial in directing the treatment of muscle tension dysphonia and improving voice training techniques. …”
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High-Performance Identification and Control of MIMO (Multiple Input—Multiple Output) Experimental Module with Fractional-Order Approach Application by Alexandre Marques de Almeida, Alisson Luan Daga, Rafael Palma Setti Penteado Lanzarini, Ervin Kaminski Lenzi, Marcelo Kaminski Lenzi

“…By considering a previously reported experimental set-up similar to a greenhouse, this study proposes the open-loop identification of fractional order transfer functions relating to the controlled and manipulated variables, which were validated by experimental data. …”
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Unveiling potential: Hybrid nanofluid-driven strategies for maximizing electrical efficiency in Photovoltaic Thermal Systems with trapezoidal flow channel for coolant purposes by A.A. Alderremy, Abid A. Memon, A.M. Obalalu, T.H. El-Ghareeb, Amsalu Fenta

“…The PV/T system features a simple configuration, with mono-crystalline silicon above the flow channel, copper functioning as the absorber, and a trapezoidal-shaped flow channel. …”
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Tetramethylpyrazine Analogue T-006 Protects Neuronal and Endothelial Cells Against Oxidative Stress via PI3K/AKT/mTOR and Nrf2 Signaling by Guiliang Zhang, Zirong Liang, Yuqiang Wang, Zaijun Zhang, Pui-Man Hoi

“…T-006 has been shown to improve neurological and behavioral functions in animal models of ischemic stroke and neurodegenerative diseases. …”
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Critical risks of haemoadsorption for COVID-19 patients and directions for future evaluations: a nationwide propensity score matched cohort study by Jan Andreas Kloka, Thomas Jasny, Oliver Old, Elina Nürenberg-Goloub, Christina Scharf, Patrick Meybohm, Alexander Supady, Kai Zacharowski, Benjamin Friedrichson

“…Two-sided probability values for group comparisons and regression models with spline functions controlling for non-linear relationships and medically relevant interaction variables were calculated. …”
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In silico studies to understand the interactions of flavonoid inhibitor with nsp12-RNA dependent RNA polymerase of SARS-CoV-2 and its homologs by Shamiya Anwar Kizhakkiniyakath, Tejaswini Choudhury, Madhan Vishal Rajan, Sagar Rathee, Basant Meena, Gururao Hariprasad

“…Complexes with the top inhibitor molecule were modelled using Discovery Studio and Desmond suite of programs. …”
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Light scattering and microphysical properties of atmospheric bullet rosette ice crystals by S. W. Wagner, S. W. Wagner, M. Schnaiter, M. Schnaiter, M. Schnaiter, G. Xu, G. Xu, F. Rogge, F. Rogge, E. Järvinen, E. Järvinen

“…This study will provide a valuable in situ dataset that can be used as a basis for the development of future ice optical models.</p>…”
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A brief exploration of the physical properties of single living cells under dynamic loading conditions by Dasen Xu, Chongyu Zhang, Ruining Peng, Ruining Peng, Ru Zhang, Haoyu Chen, Yulong Li, Yulong Li, Hui Yang, Hui Yang

“…Introduction:Single living cells exhibit both active biological functions and material-like mechanical behaviors. While extensive research has focused on static or quasi-static loading, the purely mechanical properties under high-rate impact remain underexplored. …”
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Advances in CAR T cell therapy: antigen selection, modifications, and current trials for solid tumors by Safwaan H. Khan, Safwaan H. Khan, Yeonjoo Choi, Mysore Veena, Mysore Veena, John K. Lee, John K. Lee, Daniel Sanghoon Shin, Daniel Sanghoon Shin

“…An examination of emerging strategies for countering these limitations reveals that CRISPR-Cas9-mediated genetic modifications and combination therapies utilizing checkpoint inhibitors can improve CAR T cell functionality and durability. By integrating insights from preclinical models, clinical trials, and innovative engineering approaches, this review addresses advances in CAR T cell therapies and their performance in solid tumors.…”
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Co-encapsulated Ce6 + CpG and biopeptide-modified liposomes for enhanced transdermal photo-immunotherapy of superficial tumors by Shaozhen Wang, Chen Yang, Yuanyuan Zhang, Yi Hu, Lan Xiao, Weiping Ding, Bensheng Qiu, Fenfen Li

“…In both melanoma and breast cancer murine models, Ce6/CpG@Lip-TD demonstrated substantial tumor-suppressing properties, along with an augmented systemic immune response against distal tumors. …”
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H1N76/77 deamidation facilitates chromatin remodelling and genome stability during DNA damage repair by Tingting Feng, Mengyan Li, Chenmiao Hu, Yuan Tian, Wei‐Guo Zhu

“…Following DNA double‐strand breaks, the metabolic enzyme phosphorylated CTP synthase 1 (CTPS1) functions as a deamidase, catalyzing the rapid conversion of H1 residues Asn76 and Asn77 into aspartate. …”
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Magnification Bias Reveals Severe Contamination in Hubble Frontier Field Photo-z Catalogs by Jiashuo Zhang, Jeremy Lim, Tom Broadhurst, Sung Kei Li, Man Cheung Li, Giorgio Manzoni, Rogier Windhorst

“…Gravitational lensing by massive galaxy clusters enables faint distant galaxies to be more abundantly detected than in blank fields, thereby allowing one to construct galaxy luminosity functions (LFs) to an unprecedented depth at high redshifts. …”
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Disseminating the Past in 3D: O Corro dos Mouros and Its Ritual Landscape (Galicia, Spain) by Mariluz Gil-Docampo, Rocío López-Juanes, Simón Peña-Villasenín, Pablo López-Fernández, Juan Ortiz-Sanz, María Pilar Prieto-Martinez

“…The study evaluates both the capabilities and limitations of this integrated approach, focusing on a recently identified <i>Roda</i>-type structure, characterised by circular stone architecture and funerary-ritual functionality, dating between the 15th and 3rd centuries BC. …”
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SLAMF7 (CD319) enhances cytotoxic T-cell differentiation and sensitizes CD8+ T cells to immune checkpoint blockade by Jan-Erik Sander, Irina Han, Lisette Fickenscher, Jörg-Peter Schmidt, Hartmut Kroll, Tereza Vosikova, Martin Durisin, Holger Lingel, Monika C. Brunner-Weinzierl

“…Tumors frequently evade immune destruction by impairing cytotoxic CD8+ T-cell responses, highlighting the need for strategies that restore T-cell functionality. Here, we identify SLAMF7 (CD319) as a key enhancer of human CD8+ T-cell responses against tumors. …”
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Synthesis of Zn/Al layered double hydroxides magnetic-nanoparticle for removal of humic acid by Yuan Bai, Rui Ma, Zongxian Jing, Xinwen Wan, Jingyan Tong, Weiting Huang, Jie Liu

“…A novel adsorbent of Zn/Al-LDH functionalized magnetic composite nanomaterial was successfully synthesis using a hydrothermal co-precipitation approach with NaOH as precipitating agent, and applied for the removal of humic acid (HA) from aqueous solution. …”
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Selective depletion of metastatic stem cells as therapy for human colorectal cancer by María Virtudes Céspedes, Ugutz Unzueta, Anna Aviñó, Alberto Gallardo, Patricia Álamo, Rita Sala, Alejandro Sánchez‐Chardi, Isolda Casanova, María Antònia Mangues, Antonio Lopez‐Pousa, Ramón Eritja, Antonio Villaverde, Esther Vázquez, Ramón Mangues

“…Colorectal cancer (CRC) cells overexpressing CXCR4 display trafficking functions and metastasis‐initiating capacity. We assessed the antimetastatic activity of a nanoconjugate (T22‐GFP‐H6‐FdU) that selectively delivers Floxuridine to CXCR4+ cells. …”
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Puerarin pretreatment provides protection against myocardial ischemia/reperfusion injury via inhibiting excessive autophagy and apoptosis by modulation of HES1 by Yong Yuan, Songqing Lai, Tie Hu, Fajia Hu, Chenchao Zou, Xiuqi Wang, Ming Fang, Jichun Liu, Huang Huang

“…In vivo MIRI and in vitro anoxia/reoxygenation (A/R) models were constructed. The results demonstrated that Pue pretreatment effectively alleviated MIRI, as manifested by diminishing the levels of serum CK-MB and LDH, mitigating the extent of myocardial infarction and enhancing cardiac functionality. …”
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