Dual stimuli-responsive prodrug co-delivery nanosystem of salicylic acid and bioavailable silicon for long-term immunity in plant by You Liang, Yuehong Du, Yuchen Song, Sijin Wang, Can Zhao, Zhiming Feng, Shimin Zuo, Fengping Yang, Ke Xu, Zhongyang Huo

“…In this study, a novel amidase- and redox-responsive codelivery nanosystem was developed by covalently linking salicylic acid (SA) to functionalized disulfide-doped mesoporous silica nanoparticles (MSNs-ss-NH2) for the efficient delivery of SA and bioavailable silicon concurrently. …”
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Coaxial Electrospun ZIF‐8@PAN Nanofiber Membranes for Tetracycline and Doxycycline Adsorption in Wastewater by Pu Wang, Yanan Liu, Wei He, Yaoning Chen, Jianfeng Zhou, Deng‐Guang Yu

“…Abstract In this study, polyacrylonitrile (PAN) nanofibers functionalized with ZIF‐8 (ZIF‐8@PAN), exhibiting a core‐shell structure, are produced via coaxial electrospinning for removing tetracycline (TC) and doxycycline (DC). …”
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Inhibition of LINC01048 decreases cell proliferation and induces the apoptosis in gastric cancer by Jinxi Huang, Weiwei Yuan, Gaofeng Li, Beibei Chen, Lihong Wang, Yulong Chen, Hai Huang

“…However, the mechanisms underlying these functions remain largely unknown. In this study, we investigate the role of the LINC01048 in tumorigenesis and cell proliferation in GC cell lines, such as HGC27 and MKN45. …”
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Advanced biomaterial strategies for overcoming age-associated wound healing impairments by Rodrigo Dores, Telma A. Rodrigues, Daniel Carvalho, Eva Batista, Myroslava Kozak, Cristina Blanco-Elices, Hugo Fernandes, Luis M. Bimbo

“…Concurrently, composite biomaterials, which combine multiple functionalities in a single platform, have gained prominence as particularly promising clinical solutions. …”
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State of nature 2023 terrestrial and freshwater animal dataset for the United Kingdom and its constituent countriesZenodo by Fiona Burns, Simone Mordue, Nida Al-Fulaij, Philipp Boersh-Supan, Katherine L. Boughey, Philip Briggs, Mark A. Eaton, Colin Harrower, Angus C. Jackson, Steve Langton, Francesca Mancini, David Noble, Chris R. Shortall, Chloë A. Smith, Robin J. Pakeman

“…Trend data for long- (1970–2020/21) and short-term (2010–2020) periods have been calculated by fitting statistical models to measures of abundance (753 species) or occupancy (4979 species) across the UK. …”
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The buffering effect of secure base leadership on the relationship between emotional demands and burnout: A multilevel study among military officer cadets by María C. Navas-Jiménez, Ana Laguía, Patricia Recio, Carlos García-Guiu, Alberto Pastor, Sergio Edú-Valsania, Fernando Molero, Mario Mikulincer, Juan A. Moriano

“…At the team level (Level 2), cadets who perceive their leaders as a secure base report lower levels of burnout, indicating that SBL functions as a key job resource that mitigates stress-related outcomes. …”
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Alcohol vs. Cocaine: Impulsivity and Alexithymia in Substance Use Disorder by Alessio Mosca, Giovanna Bubbico, Clara Cavallotto, Stefania Chiappini, Rita Allegretti, Andrea Miuli, Carlotta Marrangone, Nicola Ciraselli, Mauro Pettorruso, Giovanni Martinotti

“…Among the most prevalent substances of abuse, alcohol and cocaine are known to exert distinct effects on neuropsychological functioning. This study aimed to compare individuals with Alcohol Use Disorder (AUD) and Cocaine Use Disorder (CUD) in terms of impulsivity and alexithymia, and to examine the clinical implications of poly-substance use involving both alcohol and cocaine. …”
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Structural Basis and Mechanism of a Unique Haemophore in the Haem‐Iron Acquisition by Riemerella anatipestifer by Mengying Wang, Dandan Zhang, Xiu Tian, Jiangyang Tong, Yizhou Yao, Mingshu Wang, Dekang Zhu, Renyong Jia, Shun Chen, Xinxin Zhao, Shaqiu Zhang, Juan Huang, Xumin Ou, Bin Tian, Di Sun, Yu He, Zhen Wu, Songying Ouyang, Mafeng Liu, Anchun Cheng

“…Finally, the homologues of RhuH in Riemerella columbina, Flavobacterium columnare, and Flavobacterium soli are used as a proof of concept, demonstrating that these homologues exhibit conserved structures and functions.…”
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Exploring the Structural Diversity and Biotechnological Potential of the Rhodophyte Phycolectome by Éllen F. Rodrigues, Flavia Alves Verza, Felipe Garcia Nishimura, Renê Oliveira Beleboni, Cedric Hermans, Kaat Janssens, Maarten Lieven De Mol, Paco Hulpiau, Mozart Marins

“…Lectins have various biological functions, including cell signaling, molecular recognition, and innate immune responses, which play multiple roles in the physiological and developmental processes of organisms. …”
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Snhg18 regulates Yap subcellular localization to maintain bone homeostasis by Jie Huang, Yuteng Weng, Yanhuizhi Feng, Di Wu, Yongliang Chen, Zeyuan Li, Xue Jiang, Haicheng Wang, Zuolin Wang

“…Here, we identify small nucleolar RNA host gene 18 (lnc-Snhg18), a functionally conserved lncRNA enriched in the osteolineage of leptin receptor–positive (LepR⁺) cells within bone, as a key regulator promoting osteogenesis. …”
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Optimization of cultural conditions for pectinase production by Diaporthe isolate Z1-1N and its pathogenicity on kiwifruit by Shu-Dong Zhang, Ling-Ling Chen, Chao-Yue Li, Xiao-Qing Long, Xue Yang, Xiao-Duo He, Li-Wen Du, Heng-Feng Yang, Li-Zhen Ling

“…These findings underscore the significance of PG and PMG as key virulence factors in the pathogenicity of Diaporthe Z1-1N, providing a solid scientific basis for future research into the functions of these enzymes.…”
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Insulin-like growth factor 2 reduces Huntington’s disease aggregates via AKT and NF-κB signaling in huntington’s disease by Yun-Shiuan Tung, Chih-Wei Tung, Siew Chin Chan, Yi-Ching Chen, Po-Ming Wu, Pei-Hsun Cheng, Chuan-Mu Chen, Shang-Hsun Yang

“…Based on previous studies, Insulin-like growth factor 2 (IGF2) enhances microfilament polymerization in HD models; however, the role of IGF2 against mHTT aggregates is still unclear. …”
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Socio-ecological dynamics of Andean treelines in the 21st century by Gwendolyn Peyre, Enrique Zuñiga, Andrea Cornejo Paredes, Aremi Paja Medina, Jose Alfredo Sulla Torres, Manuel Zúñiga Carnero, Karina Rosas Paredes

“…Moreover, human influence has transformed treeline areas for millenia, by affecting their position, composition and ecological functions. Agriculture, livestock grazing and fires are primarily responsible for stalling many Andean treelines in their upslope migration today. …”
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Mapping strain and structural heterogeneities around bubbles in amorphous ionically conductive Bi2O3 by Ellis Rae Kennedy, Stephanie M. Ribet, Ian S. Winter, Caitlin A. Kohnert, Yongqiang Wang, Karen C. Bustillo, Colin Ophus, Benjamin K. Derby

“…Although considering structural heterogeneity in amorphous systems is non-trivial, these features have crucial impacts on material functionalities, such as mechanical strength, ionic conductivity, and electronic mobility.…”
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Shared and distinct neural signatures of feature and spatial attention by Anmin Yang, Jinhua Tian, Wenbo Wang, Liqin Zhou, Ke Zhou

“…Our study challenges traditional network-centric models of attention, emphasizing distributed brain functioning in attention, and provides comprehensive evidence for shared and distinct neural mechanisms underlying FA and SA.…”
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Interprovincial industrial virtual scarce water flow and water scarcity risk in China by Zhiliang Xu, Changxin Xu, Xueli Chen, Li Yang, Malin Song

“…“Agriculture & Fisheries” typically functioned as the source sector, whereas “Food & Tobacco” and “Construction” served as intermediate or terminal sectors. …”
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Toward an Internet of Things Circular Economy Using Printed Circuits on Reusable Steel Substrates by Jeff Kettle, Rudra Mukherjee, Shoushou Zhang, Tianwei Zhang, Jonathan Harwell, Andrew Bainbridge, Mahmoud Wagih, Ana Martinez Diez, MariFe Menendez Suarez, Pascal Sanchez

“…Herein, we present the functionalization of steel over large areas with low‐cost insulative intermediate layers as Printed Circuit Boards (PCBs), enabling an electronics circular economy. …”
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AI-enhanced profiling of phage-display-identified anti-TIM3 and anti-TIGIT novel antibodies by Astrid Musnier, Yannick Corde, Adrien Verdier, Mélanie Cortes, Jean-René Pallandre, Christophe Dumet, Adeline Bouard, AbdelRaouf Keskes, Zakaria Omahdi, Vincent Puard, Anne Poupon, Thomas Bourquard

“…The predicted epitopes allowed us to anticipate a competition with TIM3 and TIGIT binding partners, and to infer the antagonistic functions expected from these antibodies. This study lays the foundations of a multidimensional AI-driven selection of lead candidates derived from high throughput analysis.…”
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Sustaining Biodiversity and Ecological Roles in a Heritage Landscape: The Role of Coffee Agroforestry in Kluncing, Indonesia by Agung Sih Kurnianto, Nilasari Dewi, Hari Sulistyowati, Arif Mohammad Siddiq, Tri Ratnasari, Husnul Khowatini, Roni Yulianto, Anggun Sausan Firdaus

“… This study investigates the role of coffee agroforestry in sustaining biodiversity and ecosystem functions in Kluncing, Ijen, Indonesia. By quantifying bird, butterfly, and coffee insect diversity using the Shannon-Wiener index, it evaluates ecological dynamics and their implications for sustainable land management. …”
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A Multifunctional Fe-EGCG@RSL3 Nanomedicine Synergizes Ferroptosis Induction and Tumor Microenvironment Remodeling for Enhanced Bladder Cancer Immunotherapy by Chengjunyu Zhang, Sen Liu, Jianhui Zhang, Junlin Lu, Zehua Chen, Bolin Pan, Chu Liu, Ming Huang, Hengji Zhan, Hongjin Wang, Siting Chen, Kaiwen Jie, Baoqing He, Jingdie Wu, Ye Li, Haifeng Wang, Jing Zhao, Qiang Zhang, Xu Chen

“…Overall, Fe-EGCG@RSL3 has dual functions as a multifaceted nanomedicine that integrates ferroptosis induction with immunomodulation, offering a novel and clinically translatable strategy for bladder cancer therapy.…”
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