Intravascular delivery of an ultraflexible neural electrode array for recordings of cortical spiking activity by Xingzhao Wang, Shun Wu, Hantao Yang, Yu Bao, Zhi Li, Changchun Gan, Yuanyuan Deng, Junyan Cao, Xue Li, Yun Wang, Chi Ren, Zhigang Yang, Zhengtuo Zhao

“…Abstract Although intracranial neural electrodes have significantly contributed to both fundamental research and clinical treatment of neurological diseases, their implantation requires invasive surgery to open craniotomies, which can introduce brain damage and disrupt normal brain functions. Recent emergence of endovascular neural devices offers minimally invasive approaches for neural recording and stimulation. …”
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Enhancing Safety in Autonomous Maritime Transportation Systems with Real-Time AI Agents by Irmina Durlik, Tymoteusz Miller, Ewelina Kostecka, Polina Kozlovska, Wojciech Ślączka

“…We distinguish maritime AI agents from conventional systems by emphasizing their specialized functions, real-time processing demands, and resilience in dynamic environments. …”
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Integrated Fleet Management of Mobile Robots for Enhancing Industrial Efficiency: A Case Study on Interoperability in Multi-Brand Environments Within the Automotive Sector by David Lopes, Tiago Pereira, André Gonçalves, Francisco Cunha, Fernando Lopes, João Antunes, Victor Santos, Fernanda Coutinho, Jorge Barreiros, João Durães, Patrícia Santos, Fernando Simões, Pedro Ferreira, Elisabete Dinora Caldas de Freitas, João Pedro F. Trovão, João P. Ferreira, Nuno Miguel Fonseca Ferreira

“…It is concluded that the proposed solution contributes to industrial automation by providing an intuitive and centralized interface, enabling future expansions for new functionalities and the integration with other emerging technologies. …”
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Designing Wooden Lounge Chairs Using ZMET: From Deep Need Discovery to Value Hierarchy Construction by Yong Han, Wumin Ouyang, Hemin Du, Zebin Qiao, Daren Wei

“…The findings revealed that users expect more than basic functionality from wooden lounge chairs, seeking emotional resonance, lifestyle alignment, and identity expression. …”
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HSPA9 contributes to tumor progression and ferroptosis resistance by enhancing USP14-driven SLC7A11 deubiquitination in multiple myeloma by Na Shen, Yuan Xia, Xuxing Shen, Wei Hua, Min Shi, Lijuan Chen

“…Here, we confirmed that HSPA9 is overexpressed in MM samples and correlates with unfavorable outcomes. Functionally, HSPA9 enhances MM cell viability, ferroptosis resistance, and tumorigenicity, suggesting its oncogenic role. …”
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Artificial Intelligence in Virtual Screening: Transforming Drug Research and Discovery—A Review by Sayantani Roy, Karuppiah Nagaraj, Amit Mittal, Flora C. Shah, Kaliyaperumal Raja

“…Additionally, CHARMM software was applied for molecular dynamics simulations to calculate empirical energy functions. AI-driven algorithms such as KarmaDock and DeepDock were utilized for large-scale ligand screening and for improving protein–ligand docking accuracy. …”
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Increased IL-17, a Pathogenic Link between Hepatosplenic Schistosomiasis and Amyotrophic Lateral Sclerosis: A Hypothesis by Oswald Moling, Alfonsina Di Summa, Loredana Capone, Josef Stuefer, Andrea Piccin, Alessandra Porzia, Antonella Capozzi, Maurizio Sorice, Raffaella Binazzi, Lathá Gandini, Giovanni Rimenti, Peter Mian

“…The immune system protects the organism from foreign invaders and foreign substances and is involved in physiological functions that range from tissue repair to neurocognition. …”
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Her IMPROVE TEACHERS' INNOVATIVE DIGITAL SKILLS ACROSS EUROPE by Ana Afonso, Isabel Cristina Carvalho, José Bidarra, Lina Morgado, Antonieta Rocha

“…This data informed a pilot program with 80 Vocational Education and Training and Higher Education teachers to test the functionality of the digital Toolkit, the e-learning platform, design, quality, and impact of the content. …”
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Pasión y sentido en tiempos de cambio: The Way We Live Now como una propuesta de sociedad moderna en Inglaterra a finales del siglo XIX by Anderzon Medina Roa

“…From the perspective of semiotics of passions, The Way We Live Now functions as a satire that criticized the changing social values in England by the end of the century. …”
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Virtual Instrument for a Multi-illumination Dome System by M. A. Khanesar, H. Corcoran, L. MacDonald, V. Pawar, S. Robson, S. Piano

“…The reliability of the blender environment is investigated for simulating the functions of components of this system. The high-precision three-dimensional (3D) mesh of an object measured with a laser tracker equipped with an AS1 scanner is used as a digital object within this virtual instrument. …”
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Bacteria‐responsive transformable peptide‐based nanomaterials inspired by human α‐defensin 6 for labeling and entrapping pathogenic bacteria by Chenlong Zhou, Qi Tang, Peng Tan, Tao Wang, Yucheng Zhang, Shuaikang Yang, Guanghui Zhao, Yue Feng, Xi Ma

“…Specifically, PBANs self‐assemble to form nanoparticles in physiological environments and in situ transform into nanofibers on bacterial surfaces through receptor‐ligand interactions in infected microenvironments, resulting in enhanced fluorescence signal and activation of functions, while labeling and entrapping bacteria. …”
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Formal Verification of ERC-Based Smart Contracts: A Systematic Literature Review by Rim Ben Fekih, Mariam Lahami, Salma Bradai, Mohamed Jmaiel

“…ERC (Ethereum Request for Comments) standards enable a range of functionalities, such as the creation and management of tokens. …”
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Modulating the Substrate Stiffness to Manipulate Differentiation of Resident Liver Stem Cells and to Improve the Differentiation State of Hepatocytes by Angela Maria Cozzolino, Valeria Noce, Cecilia Battistelli, Alessandra Marchetti, Germana Grassi, Carla Cicchini, Marco Tripodi, Laura Amicone

“…Furthermore, standard cultivation of liver stem/precursor cells impedes an efficient execution of the epithelial/hepatocyte differentiation program, leading to the expansion of a cell population expressing only partially liver functions and products. Overcoming these limitations is mandatory for any approach of liver tissue engineering. …”
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Ankle-Foot Orthosis Made by 3D Printing Technique and Automated Design Software by Yong Ho Cha, Keun Ho Lee, Hong Jong Ryu, Il Won Joo, Anna Seo, Dong-Hyeon Kim, Sang Jun Kim

“…The 3D-printed AFO exhibited similar functionality as the conventional AFO and considerably satisfied the patient in terms of the weight and ease of use. …”
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27-Hydroxymangiferolic Acid Extends Lifespan and Improves Neurodegeneration in <i>Caenorhabditis elegans</i> by Activating Nuclear Receptors by Xiaoyan Gao, Jing Yu, Yin Li, Hang Shi, Lijun Zhang, Minglv Fang, Ying Liu, Cheng Huang, Shengjie Fan

“…27-Hydroxymangiferolic acid (27-HMA) is a naturally occurring compound in mango fruits that exhibits diverse biological functions. Here, we show that 27-HMA activates the transcriptional activity of farnesoid X receptor (FXR), a nuclear receptor transcription factor, extending the lifespan and healthspan in <i>Caenorhabditis elegans</i> (<i>C. elegans</i>). …”
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CRISPR screening reveals that RNA helicase DDX41 triggers ribosome biogenesis and cancer progression through R-loop-mediated RPL/RPS transcription by Hongquan Li, Yifei He, Jiawen Jiang, Zhen Liu, Yizhe Liu, Qili Shi, Jie Ding, Haochen Li, Weili Sun, Xin Hu, Zhiao Chen, Xianghuo He

“…Abstract The RNA helicase DDX41 is a DEAD-box helicase that is well known as a virus sensor in dendritic cells and a tumor suppressor that is frequently mutated in myeloid neoplasms. However, the functions and relevance of DDX41 in solid tumors remain largely unexplored. …”
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Microenvironment-responsive living hydrogel containing engineered probiotic for treatment of massive bone defects by Haoyu Fang, Yanyi Wang, Li Li, Xiaotong Qin, Daoyu Zhu, Pei Liu, Qianhao Yang, Youshui Gao, Zhongmin Shi, Xin Ma, Chao Zhong, Yixuan Chen

“…The emergence of microbial living therapeutics offers vast potential in regenerative medicine, as genetically engineered probiotics possess efficient stimuli-responsiveness and tunable biological functions. Here, using elevated endogenous nitric oxide (NO) signals as a biological trigger in bone fracture injuries, a Living Responsive Regenerative Medicine (LRRM) strategy for in situ bone defect repair through real-time controlled release of bone morphogenetic protein-2 (BMP2) is proposed. …”
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Novel Nonlinear Dynamical Solutions to the (2 + 1)‐Dimensional Variable Coefficients Equation Arise in Oceanography by Hajar F. Ismael, Tukur Abdulkadir Sulaiman, Harivan R. Nabi, Shams Forruque Ahmed

“…These results may be helpful in explaining the physical behavior of various nonlinear physical models.…”
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Critical Role of Skin in Pathogenesis: Bidirectional Crosstalk Between Skin and Multiple Organs by Wende Deng, Junyi Liu, Changheng Tang, Zhenghao Li, Ying Qiu, Han Zhou, Lanxuan Yang, Ting Li

“…ABSTRACT The skin, the largest organ in the human body, serves both as a mechanical barrier and an autonomous lymphoid organ, protecting against various environmental threats while maintaining the balance and functionality of multiple bodily systems. This relationship extends beyond the skin itself, involving other organs closely linked to skin homeostasis and related diseases. …”
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Insights into the Biological Activity and Bio‐Interaction Properties of Nanoscale Imine‐Based 2D and 3D Covalent Organic Frameworks by Hao Ye, Carlos Franco, Mostafa A. Aboouf, Markus Thiersch, Semih Sevim, Joaquin Llacer‐Wintle, Andrea Veciana, Gemma Llauradó‐Capdevila, Kaiyuan Wang, Xiang‐Zhong Chen, Qiao Tang, Roc Matheu, Pedro D. Wendel‐Garcia, Pedro A. Sánchez‐Murcia, Bradley J. Nelson, Cong Luo, Josep Puigmartí‐Luis, Salvador Pané

“…Their customizable functionalities and tunable pore structures make them valuable for various biomedical applications such as biosensing, bioimaging, antimicrobial activity, and targeted drug delivery. …”
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