Reciprocal Benefits of Mass-Univariate and Multivariate Modeling in Brain Mapping: Applications to Event-Related Functional MRI, H215O-, and FDG-PET by James R. Moeller, Christian G. Habeck

“…In brain mapping studies of sensory, cognitive, and motor operations, specific waveforms of dynamic neural activity are predicted based on theoretical models of human information processing. For example in event-related functional MRI (fMRI), the general linear model (GLM) is employed in mass-univariate analyses to identify the regions whose dynamic activity closely matches the expected waveforms. …”
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Auditory function in the Tc1 mouse model of down syndrome suggests a limited region of human chromosome 21 involved in otitis media. by Stephanie Kuhn, Neil Ingham, Selina Pearson, Susan M Gribble, Stephen Clayton, Karen P Steel, Walter Marcotti

“…All physiological properties investigated in OHCs were indistinguishable between the two genotypes. The normal functional hearing and the gross structural anatomy of the middle and inner ears in the Tc1 mouse contrast to that observed in the Ts65Dn model of Down syndrome which shows otitis media. …”
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The prognostic model of low-grade glioma based on m6A-associated immune genes and functional study of FBXO4 in the tumor microenvironment by Yiling Zhang, Na Luo, Xiaoyu Li, Chuanfei Zeng, Xin Chen, Xiaohong Peng, Yuanyuan Zhang, Guangyuan Hu

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CONCEPTUAL (STRUCTURAL-FUNCTIONAL) MODEL OF ORGANIZATIONAL-ECONOMIC MECHANISM OF INSTITUTIONAL MODERNIZATION OF THE HIGHER SCHOOL AS A DRIVER FOR INNOVATIVE TRANSFORMATION OF THE ECONOMIC SYSTEM OF RUSSIA by V. Ovchinnikov, A. Oganyan

“…Conceptual and methodological aspects of the study of the features of the development and formalization of the conceptual (structural and functional) model of the organizational and economic mechanism of institutional modernization of higher education in Russia have been adduced. …”
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Modelling and Optimization of Fluid Frictional Torque in a Single Stage Centrifugal Pump with a Vaned Diffuser Based on RSM, ANN and Desirability Function by K. Singh, A. Singh, D. K. Singh

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A HYPOTHETICAL FUNCTIONAL MODEL OF SOCIO-DEMOGRAPHIC DEVELOPMENT BASED ON THE RELATIONSHIP BETWEEN THE INCOME HETEROGENEITY OF THE RURAL POPULATION AS A FACTOR OF SOCIAL DYNAMICS by Marina Alexandrovna VOLOKHOVA, Ivan Sergeevich NOVIKOV

“…The hypothetical substantiation of the dependence of economic indicators of value heterogeneity in terms of economic indicators of society and social dynamics was tested on the basis of a hypothetical model based on matrix algorithms. A model of socio-demographic development has been developed based on the relationship between the value heterogeneity of the rural population as a factor of social dynamics, uniting a system of economic and social indicators on the basis of a functional approach, stratification indicators of the value orientation of rural areas have been determined depending on the level of income of the population, which will determine the growth of job creation. places and size of wages. …”
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THE ROLE OF GENETICALLY DETERMINED BODY RESISTANCE OF WARM-BLOODED ANIMALS TO HYPOXIA IN THE REALIZATION OF EFFECTOR FUNCTIONS OF NEUTROPHILS IN THE MODEL OF ADJUVANT-INDUCED RHEUMATOID ARTHRITIS by Elena Georgievna Pukhaeva, Alibek Kirilovich Badtiev, Fatima Elbrusovna Salamova, Stanislav Georgievich Dzgoev, Alina Muratbekovna Kupeeva

“…The purpose of the study: to evaluate the peculiarities of the realization of the effector functions of neutrophils in normal conditions and against the background of an induced inflammatory process in animals with genetically predetermined high and low resistance to hypoxia. …”
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Novel protocatechuic acid encapsulated bovine serum albumin functionalized folic acid nanoparticles for targeted therapy in urethane-induced lung cancer model by Alaa I. Ibrahim, Heba A. Sahyon, Adel M. Attia, Ashraf A. El-Shehawy

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Amyloidogenic immunoglobulin light chains disturb contractile function and calcium transients in a human cardiac spheroid model of light chain (AL) amyloidosis by Mélanie Bézard, Jean-Sébastien Vartanian-Grimaldi, Julien Henri, Denisa Calin, Amira Zaroui, Mounira Kharoubi, Thibaud Damy, Onnik Agbulut, Ekaterini Kordeli

“…In this work, we have set up a human cellular disease model of AL cardiac amyloidosis (AL-CA) in the form of cardiac spheroids, to study the cytotoxic effects of amyloidogenic LCs with regard to contractile function and calcium handling. …”
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Histological and functional outcomes in a rat model of hemisected spinal cord with sustained VEGF/NT-3 release from tissue-engineered grafts by Zi-Xing Xu, Li-Qun Zhang, Yi-Nan Zhou, Xue-Min Chen, Wei-Hong Xu

“…Microvascular disturbance, excessive inflammation and gliosis are key pathophysiologic changes in relation to functional status following the traumatic spinal cord injury (SCI). …”
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β3-Adrenergic receptor antagonism improves cardiac and vascular functions but did not modulate survival in a murine resuscitated septic shock model by Eugénie Hagimont, Marc-Damien Lourenco-Rodrigues, Benjamin-Glenn Chousterman, Frances Yen-Potin, Manon Durand, Antoine Kimmoun

“…Abstract Background Recent findings suggest that β3-adrenergic receptors (β3-AR) could play a role in the hemodynamic regulation, but their function in septic shock remains unclear. This study investigates the modulation of β3-AR in an experimental murine model of resuscitated septic shock on in vivo hemodynamic, ex vivo vasoreactivity, inflammation and survival. …”
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Author Correction: Cell-mediated exon skipping normalizes dystrophin expression and muscle function in a new mouse model of Duchenne Muscular Dystrophy by Francesco Galli, Laricia Bragg, Maira Rossi, Daisy Proietti, Laura Perani, Marco Bacigaluppi, Rossana Tonlorenzi, Tendai Sibanda, Miriam Caffarini, Avraneel Talapatra, Sabrina Santoleri, Mirella Meregalli, Beatriz Bano-Otalora, Anne Bigot, Irene Bozzoni, Chiara Bonini, Vincent Mouly, Yvan Torrente, Giulio Cossu

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Magnetic Field Distribution and Signal Decay in Functional MRI in Very High Fields (up to 9.4 T) Using Monte Carlo Diffusion Modeling by Bernd Michael Mueller-Bierl, Kamil Uludag, Philippe L. Pereira, Fritz Schick

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Multi-Layer Modeling and Visualization of Functional Network Connectivity Shows High Performance for the Classification of Schizophrenia and Cognitive Performance via Resting fMRI by Duc My Vo, Anees Abrol, Zening Fu, Vince D. Calhoun

“…<b>Background:</b> In functional magnetic resonance imaging (fMRI), functional network connectivity (FNC) captures temporal coupling among intrinsic connectivity networks (ICNs). …”
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Interval valued inventory model with different payment strategies for green products under interval valued Grey Wolf optimizer Algorithm fitness function by Subhash Chandra Das, Md. Al-Amin Khan, Ali Akbar Shaikh, Adel Fahad Alrasheedi

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Matrilin-2 with a K-Chitosan Scaffold Enhances Functional Recovery and Nerve Regeneration in a Segmental Rat Sciatic Nerve Injury Model by Neill Y. Li, Brandon Vorrius, Elliott Rebello, Jonathan Ge, Amit Mohite, Zhen Qiao, Jing Ding, Qian Chen

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Impaired hippocampal circuit function underlying memory encoding and consolidation precede robust Aβ deposition in a mouse model of alzheimer’s disease by Hanyan Li, Zhuoyang Zhao, Aline Fassini, Han K. Lee, Reese J. Green, Stephen N. Gomperts

“…Employing hippocampal electrophysiological recordings and dynamic calcium imaging across the sleep-wake cycle in a freely behaving mouse model of AD before Aβ plaques accumulated, we detected marked impairments of hippocampal systems function: In a spatial behavioral task, phase-amplitude coupling (PAC) of the hippocampal theta and gamma oscillations was impaired and place cell calcium fluctuations were hyper-synchronized with the theta oscillation. …”
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Development of a predictive model for long-term care and support eligibility certification associated with dementia-related functional impairments: the IRIDE cohort study by Daichi Yamashiro, Hiroyuki Suzuki, Susumu Ogawa, Mari Yamashita, Hiroki Moriya, Hiroyuki Sasai, Shuichi P. Obuchi, Takumi Abe, Hiroshi Murayama, Takumi Hirata, Yoshinori Fujiwara, Shuichi Awata, Masahiro Akishita, Kenji Toba, IRIDE Cohort Study Investigators

“…Abstract Background The Long-Term Care Insurance (LTCI) system in Japan provides a framework for assessing dementia-related functional decline, enabling the development of predictive models based on daily functional independence. …”
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Multiscale Contextual Mamba: Advancing Psychiatric Disorder Detection across Multisite Functional Magnetic Resonance Imaging Datasets via State Space Modeling by Shusheng Li, Yang Bo, Yuchu Chen, Jianfeng Cao, Bo Bi, Ting Ma, Chenfei Ye

“…Methods: We propose Multiscale Contextual Mamba (MSC-Mamba), a Mamba-based model designed for capturing long-term dependencies in multivariate time-series data while maintaining linear scalability, allowing us to account for long-range interactions and subtle dynamic patterns within the brain’s functional networks. …”
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Conditional Moment Closure Modelling of a Lifted H2/N2 Turbulent Jet Flame Using the Presumed Mapping Function Approach by Ahmad El Sayed, Roydon A. Fraser

“…A lifted hydrogen/nitrogen turbulent jet flame issuing into a vitiated coflow is investigated using the conditional moment closure (CMC) supplemented by the presumed mapping function (PMF) approach for the modelling of conditional mixing and velocity statistics. …”
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