Carbon Monoxide Stimulates Chondrocyte Mitochondria and Protects Mitochondria During Cartilage Injury by Suryamin Liman, Madeline R. Hines, Piedad C. Gómez-Contreras, Emily Witt, Jacob S. Fisher, Kevin J. Lu, Lauren D. McNally, Alicia T. Cotoia, Maxwell Y. Sakyi, Brett A. Wagner, Michael S. Tift, Douglas Fredericks, Jessica E. Goetz, James D. Byrne, Mitchell C. Coleman

“…<b><i>Conclusions:</i></b> This study supports the hypothesis that CO functions as an antioxidant for articular chondrocytes by supporting mitochondria and intracellular GSH in the presence or absence of cartilage injury. …”
Get full text

Linguistic accuracy and authenticity of the content of the Russian version of the module of gastrointestinal symptoms of the PedsQL^™ questionnaire for pediatric patient... by Anna L. Arakelyan, Andrey N. Surkov, Aleksander A. Baranov, Leyla S. Namazova-Baranova, Valeri V. Gorev, Elena B. Moskvina, Tamara A. Skvorcova, Artem V. Nikitin, Vladislav V. Chernikov

“…Health Related Quality of Life (HRQL) is a person’s perception of the effect of a disease on physical, social and psychological functioning and wealth. Questionnaires that help assess the HRQL can give a concept of child’s state, identify arcane issues and they are of great importance for a full understanding of how the state of health affects the child. …”
Get full text

ANALYSIS OF POLYMORPHISM OF THE GENES OF THE PHASE II OF XENOBIOTICS BIOTRANSFORMATION (GSTM1, GSTT1) IN THE SHORIANS AND ALIEN POPULATION OF THE KEMEROVO REGION: THE PROBLEM OF TH... by Фаина Анисимовна Лузина, Анастасия Викторовна Дорошилова, Владимир Юрьевич Смирнов, Анастасия Сергеевна Казицкая, Ольга Николаевна Гуляева, Татьяна Константиновна Ядыкина, Анатолий Владимирович Колбаско

“…The indigenous Shorians are dominated by the frequencies of the non-mutant variants of the genes of xenobiotics biotransformation: GSTM1 (+) is 0.768, GSTT1 (+) is 0.743; the frequency of «null» functionally weakened genotypes and their combinations compared with the Europeoid population is reduced. …”
Get full text

Clinical significance of assessing ADAMTS-13 and von Willebrand factor level in COVID-19 convalescent pregnant women by N. R. Gashimova, K. N. Grigoreva, V. O. Bitsadze, L. L. Pankratyeva, J. Kh. Khizroeva, M. V. Tretyakova, Ya. M. Shammut, E. Iu. Iupatov, V. I. Tsibizova, J.-K. Gris, D. V. Blinov, A. D. Makatsariya

“…The ADAMTS-13/vWF ratio determines the pathway functioning, the risk of microcirculation disorders and clinical complications.…”
Get full text

Environmental enrichment affects immunity and reduces disease severity in pigs after co-infection, with stronger effects when applied from birth than from weaning by Brigitte G. C. de Bruijn, Ingrid Danielle Ellen van Dixhoorn, J. Elizabeth Bolhuis, Jan B. W. J. Cornelissen, Norbert Stockhofe-Zurwieden, Marion Kluivers, Johanna M. J. Rebel, Johanna M. J. Rebel

“…We investigated whether environmental enrichment applied at different life stages of pigs affects the susceptibility to and severity of disease by studying immune cell functions around weaning and during nursery, the effects of infection in ex vivo models and in vivo using a co-infection model of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) followed by an Actinobacillus pleuropneumoniae infection. …”
Get full text

Supramolecular nanofibers of natural asiaticoside for self-supporting gelation and enhanced transdermal delivery by Xixi Hu, Shuang Tian, Jiao Wang, Weixi Luo, Jiangli Yao, Rui Zhu, Yiyuan Dai, Hongyun Li, Yuhua Ma, Chen Liu, Wenping Wang

“…The hydrogel’s dual functionality (pH-responsive gelation and enhanced permeation) offers a sustainable platform for the transdermal delivery of hydrophobic phytochemicals, bridging phytochemistry and nanobiotechnology. …”
Get full text

Substrate-Induced Structural Dynamics and Evolutionary Linkage of Siderophore-Iron ABC Transporters of <i>Mycobacterium tuberculosis</i> by Aisha Farhana, Abdullah Alsrhani, Hasan Ejaz, Muharib Alruwaili, Ayman A. M. Alameen, Emad Manni, Zafar Rasheed, Yusuf Saleem Khan

“…<i>Results</i>: Our findings reveal that the substrate-binding domain (SBD) of IrtA functions as an active monomer, while Rv2895c, which facilitates the uptake of siderophore-bound iron, exists in a dynamic equilibrium between dimeric and monomeric forms. …”
Get full text

Synthesis, spectral characterization, biological, FMO, MEP, molecular docking, and molecular dynamics simulation studies of cytidine derivatives as antimicrobial and anticancer age... by Rahnuma Tabassum, Sarkar M.A. Kawsar, Asraful Alam, Supriyo Saha, Anowar Hosen, Imtiaj Hasan, Prinsa, Mohammed Chalkha

Get full text

Dual Strategy of Electroless Metal Deposition and Surface Silylation Toward Scalable Low-Temperature Hybrid Bonding for Advanced Packaging Applications by Zambaga Otgonbayar, Jeoung Han Kim, Jinsung Rho, Jeong-Chul Kim, Jungchul Noh, Jeonghun Kim, Seong-Ho Yoon, Chang-Min Yoon

Get full text

Dynamically Cyclic Fe2+/Fe3+ Active Sites as Electron and Proton-Feeding Centers Boosting CO2 Photoreduction Powered by Benzyl Alcohol Oxidation by Ben Lei, Gaofeng Zhou, Zhongyou Gong, Chao Liu, Ying Zhou, Vitaliy P. Guro, Yanjuan Sun, Jianping Sheng, Fan Dong

Get full text

Radial Profiles of Σ*, ΣSFR, Gas Metallicity, and Their Correlations across the Galactic Mass–Size Plane by Lin Lin, Shiyin Shen, Hassen M. Yesuf, Ye-Wei Mao, Lei Hao

Get full text

CEREBROPROTECTIVE ACTIVITY OF NEW DERIVATIVES OF PIRIMIDINE4 1H ONE PIR9 AND PIR10 IN IRREVERSIBLE OCCLUSION OF THE COMMON CAROTID ARTERY by A. V. Voronkov, N. B. Shabanova, I. P. Kodonidi, I. S. Shatalov

“…Global cerebral ischemia was modeled under chloral hydrate anesthesia (350 mg / kg) by dressing the common carotid arteries. 24 hours after the ischemia model, the survival, behavioral activity, cognitive and mnestic functions as well as certain metabolic disorders were evaluated. …”
Get full text

Heterogeneity of Antibiotic-Resistant Isolates of Listeria Monocytogenes Isolated from Food Products in Moscow by Yu. V. Mikhailova, A. D. Molchanov, A. A. Shelenkov, M. A. Tyumentseva, K. S. Karbyshev, A. I. Tyumentsev, A. E. Egorova, N. G. Kulikova, I. N. Manzenyuk, V. G. Akimkin

“…Correlation analysis confirmed their functionality.Conclusion. We believe that the whole genome data obtained for the foodborne Listeria monocytogenes isolates will facilitate and complement further epidemiological studies of this pathogen, as well as the investigations of its genome variability in terms of the acquisition of various genetic elements associated with adaptation, antimicrobial resistance, and virulence. …”
Get full text

The Effect of Combination Therapy with Melatonin on the Enzymes of Glutathione System and the Level of Transforming Growth Factor- β1 in Patients with Type 2 Diabetes Mellitus a... by S. S. Popov, E. I. Anufrieva, E. D. Kryl’skii, A. N. Verevkin, K. K. Shulgin

“…The differences observed during the study were apparently caused by the action of melatonin, which has nephroprotective and hypoglycemic properties, the ability to neutralize reactive oxygen species and activate the antioxidant system functioning.…”
Get full text

DNA-Containing Extracellular Structures of Tumor Cells Inhibit the Formation of Neutrophil Extracellular Traps <i>in vitro</i> by A. N. Kazimirskii, J. M. Salmasi, G. V. Poryadin, M. I. Panina, A. E. Kim, A. G. Chakhalian, O. O. Turishcheva

“…The effect of inhibition of neutrophil networks by K562 cells is probably due to the action of a soluble factor that suppresses neutrophil functions described earlier.Conclusion. The study shows that both tumor cell lines are capable of suppressing innate immune cell responses through different mechanisms. …”
Get full text

Environmental and genetic risk factors for Parkinson’s disease by M. A. Nikitina, V. M. Alifirova, E. Yu. Bragina, N. P. Babushkina, D. E. Gomboeva, S. M. Nazarenko

“…The severity of the disease was studied according to the MDS-UPDRS scale; the stage of PD was determined according to the Hoehn and Yahr scale. Cognitive functions were assessed by the MoCA test and MMSE. …”
Get full text

Effect of Full Mouth Oral Rehabilitation on Bite Force and Body Mass Index in Patients with Early Childhood Caries: A Study Protocol by Rutuja Pralhad Patil, Monika Khubchandani, Harikishan Kanani

“…Need of the Study: Bite force assessment in the context of full-mouth rehabilitation of ECC will help measure functionality, monitor stability, finding issues early, ensuring treatment effectiveness and recommend any necessary adjustments for the child’s best dental health, to improve post-treatment quality of life. …”
Get full text

Mathematical modeling of heat and mass transfer processes in a reciprocating engine of a vehicle with a hybrid powertrain by Fedіr Abramchuk, Vitaliy Krivda, Olha Sakno, Valentyna Olishevska, Kostyantyn Kornilenko, Olena Sakno

“…Automotive transport plays a crucial role in the functioning and development of any country's economy. …”
Get full text

Experience of using robot-assisted (da Vinci) operations in the treatment of common endometriosis by A. K. Politova, A. D. Aleksandrova, Yu. A. Vershinina, A. A. Politova, M. I. Rokhlina

“…Currently, genital endometriosis is considered as one of the most severe conditions in women of reproductive age, which has detrimental consequences for social, professional and psychological functioning. It ranks third in the structure of gynecological diseases after inflammatory diseases of the female reproductive system and uterine fibroids. …”
Get full text

Current strategies on kidney regeneration using tissue engineering approaches: a systematic review by Parham Torabinavid, Mohammad Hossein Khosropanah, Ashkan Azimzadeh, Abdol-Mohammad Kajbafzadeh

“…While periodic dialysis is beneficial, it can negatively impact a patient’s quality of life and does not fully replicate the secretory functions of the kidneys. Additionally, the scarcity of organ donors and complications associated with organ transplants have underscored the importance of tissue engineering. …”
Get full text