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701
Multicomponent rehabilitation to improve independence and functioning in elderly patients with common age-associated diseases: a scoping review
Published 2025-01-01“…This review mapped the evidence on MR in elderly patients following hospitalisation for age-related conditions regarding functioning-related outcomes.Design Scoping review.Data sources PubMed, Cochrane Library, International Clinical Trials Registry Platform and ClinicalTrials.gov (searched through 24 June 2024).Eligibility criteria We included randomised controlled trials (RCT) and controlled cohort studies (CCS) comparing centre-based MR with usual care (medical care excluding exercise training) in patients ≥75 years, hospitalised for age-related cardiac, neurological, oncological and orthopaedic diseases. …”
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702
A gene‐centered C. elegans protein–DNA interaction network provides a framework for functional predictions
Published 2016-10-01“…Although great progress has been made in mapping PDIs using chromatin immunoprecipitation, these studies have only characterized ~10% of TFs in any metazoan species. …”
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703
Analytical and numerical evaluation of the relationship between elongation calibration function and cyber standard tensile tests for ductile materials
Published 2025-05-01“…A novel analytical elongation calibration function is presented and numerically validated. This function simply maps an experimental tensile test to the analytical tensile test of the specimen with arbitrary GLPD.…”
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704
Analysis of The Wife of Bath’s Tale from Geoffrey Chaucer’s Canterbury Tales through the Lense of Propp’s Narrative Function
Published 2025-03-01“…The purpose of the investigation is to explain the structural elements of the tale using Propp's 31 narrative functions applied to folk stories. In mapping these functions onto the tale, the research underlines how Chaucer follows conventional patterns of storytelling but innovates in crucial areas, mainly when it comes to gender roles and moral redemption. …”
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705
Coffee Silverskin as a Potential Ingredient for Functional Foods: Recent Advances and a Case Study with Chocolate Cake
Published 2024-12-01“…Therefore, this study aimed to provide an overview of the latest research on CS as a potential ingredient for functional foods and to evaluate the effect of adding different amounts of CS on the functional and sensory attributes of chocolate cakes. …”
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706
Resting-State Network Transitions in Temporal Lobe Epilepsy: Insights From MEG-Based Dynamic Functional Connectivity
Published 2025-01-01“…This study explores dynamic functional connectivity (dFC) patterns in TLE patients compared to Healthy Controls (HC) using resting-state Magnetoencephalography (MEG) data. dFC, which captures the temporal variability of brain networks, was analyzed across eight frequency bands (delta, theta, alpha, beta, low gamma, mid gamma, high gamma, and broadband) in 21 TLE patients and 21 HC. …”
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707
Using Postbiotics from Functional Foods for Managing Colorectal Cancer: Mechanisms, Sources, Therapeutic Potential, and Clinical Perspectives
Published 2025-06-01“…This systematic review investigates the therapeutic potential of postbiotics derived from functional foods in the context of colorectal cancer (CRC), a leading cause of cancer-related mortality worldwide. …”
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708
Cognitive Dysfunction in Patients Treated with Androgen Deprivation Therapy: A Multimodality Functional Imaging Study to Evaluate Neuroinflammation
Published 2023-01-01“…Neuroinflammation was evaluated using positron emission tomography (PET) with the translocator protein (TSPO) radioligand [11C]-PBR28. [11C]-PBR28 uptake in various brain regions was quantified as standardized uptake value (SUVR, normalized to cerebellum) and related to blood oxygen level-dependent functional magnetic resonance imaging (BOLD-fMRI) choice-reaction time task (CRT) activation maps. …”
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709
Understanding on the association between informal caregiver characteristics and cognitive function of adults with cancer: a scoping review protocol
Published 2019-09-01“…Therefore, the body of literature related to the association between caregiver characteristics and cognitive function of adults with cancer needs to be fully mapped with assessment for knowledge gaps.Methods and analysis Methods for this scoping review was informed by the framework proposed by Arksey and O’Malley. …”
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710
Structure-function analysis of CNGA3-associated achromatopsia patient variants complements clinical genomics in pathogenicity determination
Published 2025-05-01“…Here, we present clinical features of a novel CNGA3 variant in an achromatopsia patient and demonstrate its pathogenicity by a three-dimensional (3D) proteoform-based structure-function analysis. We first identified six proteotypic groups using 47 pathogenic missense variants with distinctive functional consequences by mapping their spatial proximity in a 3D protein structure. …”
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711
Functional characterization of DPP4 and FcRn as receptor and coreceptor for classical human astroviruses in Caco-2 cells.
Published 2025-07-01“…These amino acid residues are part of the epitope footprint of neutralizing monoclonal antibodies (Nt-MAbs) to HAstV previously mapped by X-ray crystallography. Further experiments using virus infectivity and attachment assays, along with Nt-MAbs targeting HAstV-1, suggest that the binding sites for FcRn and DPP4 are spatially proximal on the viral spike, defining a functional domain for cell infection. …”
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712
Evaluation of higher cognitive functions following posterior quadrant disconnection in the non-dominant hemisphere: a Case Report
Published 2025-07-01“…In this case, the patient with drug-resistant epilepsy underwent preoperative evaluation using stereo electroencephalography (SEEG) to identify seizure onset zones and functional mapping related to visuospatial cognition. …”
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713
Patterns of Functional Diversity, Species Diversity, and Endemicity Driven by Elevation and Topographic Complexity in a Mediterranean Mountain Refuge
Published 2025-05-01“…The relationship of functional and species diversity with environmental parameters was also modeled and mapped within this study conducted with approximately 5550 records of 1017 plant taxa from 136 study plots. …”
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714
Response of Soil Microbial Diversity, Community Structure, and Functional Potential to Primary Forest Conversion in Northwestern Hunan Province
Published 2025-02-01“…[Objective] To explore the impact of primary forest conversion on soil microbial community diversity, structure and functions, in order to provide a theoretical reference for soil health preservation. …”
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716
Impact of hyperglycaemia on cellular microenvironment and function of endometrium and uterine tube: scoping review focused on infertility in diabetic women
Published 2025-05-01“…We also hypothesize how DM may affect the function of immune cells in uterine tube and uterus, including changes in the number and types of cells of innate and acquired immunity, disrupting immunological barrier in uterine tube, alterations in formation of neutrophil extracellular traps or polarization of macrophages.DiscussionWe discuss evidence for clinical practice in terms of glycaemic control, lifestyle modifications, and medical interventions. …”
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717
White-Matter fiber tract and resting-state functional connectivity abnormalities in young children with autism spectrum disorder
Published 2025-04-01“…Although abnormal brain development has been shown to exist in children with ASD, the link between structural brain abnormalities and resting-state functional connectivity (rsFC) disruptions in children with ASD remains understudied. …”
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718
Lung function may recover after coal mine fire smoke exposure: a longitudinal cohort study
Published 2024-12-01“…For post-bronchodilator reactance and area under the curve, a negative impact of PM2.5 in round 1 showed signs of recovery in round 2 (both p<0.001).Conclusion In this novel study evaluating long-term respiratory outcomes after medium-duration high concentration PM2.5 exposure, the attenuated associations between exposure and respiratory function may indicate some recovery in lung function. …”
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719
Changing grizzly bear space use and functional connectivity in response to human disturbance in the southern Canadian Rocky Mountains
Published 2025-08-01“…We used integrated step‐selection functions (iSSF) to model movement and habitat selection for 109 GPS‐collared grizzly bears across an 85,000 km2 multi‐use landscape in southeastern British Columbia and southwestern Alberta. …”
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720