Evolutionary tinkering with conserved components of a transcriptional regulatory network. by Hugo Lavoie, Hervé Hogues, Jaideep Mallick, Adnane Sellam, André Nantel, Malcolm Whiteway

“…Changes occurred in transcription factor wiring with cellular functions, movements in transcription factor hierarchies, DNA-binding specificity, and regulatory complexes assembly to promote global changes in the architecture of the fungal transcriptional regulatory network.…”
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Modelling soil prokaryotic traits across environments with the trait sequence database ampliconTraits and the R package MicEnvMod by Jonathan Donhauser, Anna Doménech-Pascual, Xingguo Han, Karen Jordaan, Jean-Baptiste Ramond, Aline Frossard, Anna M. Romaní, Anders Priemé

“…Overall, our approach enables robust inference of ecologically interpretable traits combined with environmental modelling allowing to harness traits as bioindicators of soil ecosystem functioning.…”
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Specific features of using historical and cultural resources of the Ukrainian-Polish borderland for tourism purposes by Stepan Kuzyk, Daryna Lytvyn

“…Also, it analyses the tourist itineraries functioning on the territory of the Ukrainian and Polish borderland. …”
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Volume electron microscopy for genetically and molecularly defined neural circuits by Nobuhiko Ohno, Fuyuki Karube, Fumino Fujiyama

“…These advancements are expected to reveal mechanisms for processing adaptive changes in specific neural circuits that modulate brain functions.…”
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Integrative analysis of KEAP1/NFE2L2 alterations across 3600+ tumors reveals an NRF2 expression signature as a prognostic biomarker in cancer by Valentina Crippa, Nicoletta Cordani, Alberto Maria Villa, Federica Malighetti, Matteo Villa, Luca Sala, Andrea Aroldi, Rocco Piazza, Diego Cortinovis, Luca Mologni, Daniele Ramazzotti

“…Our study identified novel NRF2-related functionalities associated with specific genetic alterations and revealed a KEAP1/NFE2L2 expression signature predictive of prognosis across different cancer types. …”
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Research on time synchronization of linear pulse-coupled oscillators model with delay in nearest neighbor wireless multi-hop networks by Lizhen Cui, Jian Cao, Zhulin An, Yong Yang, Qianqian Guo

“…Second, we mathematically analyze the firing behaviors in the linear pulse-coupled oscillators network using the delayed excitatory coupling and track the synchronization process of the two and multi-oscillators and obtain the synchronization conditions from the regression mapping. Finally, through the proposed model implementation in the wireless sensor networks simulation framework, we demonstrate that the multi-oscillators system can be synchronized from a random starting stage distribution under linear phase responding functions and the nearest neighbor communication. …”
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Revealing homoclinic breather waves, periodic lump waves and other waves forms of an integrable reduced spin Hirota-Maxwell-Bloch system by Baboucarr Ceesay, Muhammad Waqas Yasin, Nauman Ahmed, Muhammad Zafarullah Baber, Ebrima Bittaye

“…Finally, as far as we could verify, this is the first work in the literature in which these ansatz functions are derived for this integrable reduced spin Hirota-Maxwell-Bloch system using logarithmic transformations.…”
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Emergent topological polarization textures in relaxor ferroelectrics by Maksim Eremenko, Victor Krayzman, Semen Gorfman, Alexei Bosak, Helen Y. Playford, Philip A. Chater, Bruce Ravel, William J. Laws, Feng Ye, Arianna Minelli, Bi-Xia Wang, Zuo-Guang Ye, Matthew G. Tucker, Igor Levin

“…In this work, our results suggest that chemical disorder, acting via depolarizing and strain fields, stabilizes topological vortex textures of the polarization field, offering a route for engineering new dielectric and ferroelectric functionalities.…”
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CMOS-integrated organic neuromorphic imagers for high-resolution dual-modal imaging by Salihuojia Talanti, Kerui Fu, Xiaolong Zheng, Youzhi Shi, Yimei Tan, Chenxi Liu, Yanfei Liu, Ge Mu, Qun Hao, Kangkang Weng, Xin Tang

“…The neuromorphic device demonstrates adjustable memory behavior through modulation of charge recombination-trapping dynamics, enabling multi-level memory functionality. We further developed a CMOS-compatible photolithography method, which supports high-resolution and non-destructive patterning of organic neuromorphic devices. …”
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Footprint-C reveals transcription factor modes in local clusters and long-range chromatin interactions by Xiaokun Liu, Hanhan Wei, Qifan Zhang, Na Zhang, Qingqing Wu, Chenhuan Xu

“…These methods often fragment the genome using enzymes functionally irrelevant to the interactions per se, restraining the efficiency in identifying structural features and the underlying regulatory elements. …”
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A scoping review on human-centered design approaches and considerations in the design of technologies for loneliness and social isolation in older adults by Freya Probst, John Ratcliffe, Erika Molteni, Nikitia Mexia, Jessica Rees, Faith Matcham, Michela Antonelli, Anthea Tinker, Yu Shi, Sebastien Ourselin, Wei Liu

“…However, more research is needed on stakeholder perspectives, the functioning of applications in different housing environments, as well as studies that include diverse socio-economic groups.…”
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Service Composition and Optimal Selection for Industrial Software Integration with QoS and Availability by Yangzhen Cao, Shanhui Liu, Chaoyang Li, Hongen Yang, Yuanyang Wang

“…Extensive experiments were conducted, including performance evaluation on 17 benchmark functions and case studies involving nine industrial software integration scenarios of varying scales. …”
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Rotor Location During Atrial Fibrillation: A Framework Based on Data Fusion and Information Quality by Miguel A. Becerra, Diego H. Peluffo-Ordoñez, Johana Vela, Cristian Mejía, Juan P. Ugarte, Catalina Tobón

“…The proposed framework outperformed existing EGM-based rotor detection methods, demonstrating superior functionality and performance compared to existing EGM-based rotor detection methods. …”
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ExActR: A Shiny app for creating ecosystem extent accounts by Anthony Gibbons, Francesco Martini, Cian White, Emma King, Jane C. Stout, Ian Donohue, Andrew Parnell

“…The app is suitable for using with any spatial grouping variable. We test its functionality on small and large study sites on CORINE land cover data, as well as land cover maps generated using very-high resolution satellite imagery of a wind farm site in Ireland, during and post construction, demonstrating its ability to adapt to various land cover classification systems. …”
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Iterative SCRaMbLE for engineering synthetic genome modules and chromosomes by Xinyu Lu, Klaudia Ciurkot, Glen-Oliver F. Gowers, William M. Shaw, Tom Ellis

“…Here, we demonstrate how iterative cycles of SCRaMbLE reorganises synthetic genome modules and chromosomes to improve functions. We introduce SCOUT (SCRaMbLE Continuous Output and Universal Tracker), a reporter system that allows sorting of SCRaMbLEd cells into high-diversity pools. …”
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Key Topics and Case Studies in Pragmatics: Examples of Corpus-based Research by Mohammad Amin Hawamdeh, Mohammad H. Al Aqqad, Ahmad Ali Mahamdeh

“…The findings demonstrate that operationalizing stylistic conventions in sacred texts enables replicable annotation frameworks for both translation studies and digital religious discourse; that implicature analysis can reveal culturally nuanced meaning negotiation relevant to online communication; and that hierarchical mapping of hedging functions provides a transferable model for monitoring rhetorical strategies in both traditional and digital political messaging. …”
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Visual Scheme for the Detection of Mobile Attack on WSN Simulator by Young-Sik Jeong, Hyun-Woo Kim, Jong Hyuk Park

“…Sensors can be efficiently arranged through this sensor node information, and when the sensors have been arranged, security simulation functions applied with data encryption for data transmission between sensor nodes are provided. …”
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Global properties of nuclei and drip lines at finite temperature by Paar Nils, Ravlić Ante, Nikšić Tamara, Yüksel Esra

“…We also investigated critical properties such as neutron emission lifetimes, quadrupole deformations, neutron skin thickness, and pairing gaps as functions of temperature. Findings show that, while finite-temperature effects are modest up to T ≈ 1 MeV, they become increasingly significant at higher temperatures, reducing deformations and weakening shell closures. …”
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Variation in molybdenum content across broadly distributed populations of Arabidopsis thaliana is controlled by a mitochondrial molybdenum transporter (MOT1). by Ivan Baxter, Balasubramaniam Muthukumar, Hyeong Cheol Park, Peter Buchner, Brett Lahner, John Danku, Keyan Zhao, Joohyun Lee, Malcolm J Hawkesford, Mary Lou Guerinot, David E Salt

“…Furthermore, expression of MOT1 specifically enhances Mo accumulation in yeast by 5-fold, consistent with MOT1 functioning as a molybdate transporter. This work provides the first molecular insight into the processes that regulate Mo accumulation in plants and shows that novel loci can be detected by association mapping.…”
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An evaluation of barriers and facilitators to implementing multiplex rapid antigen testing for SARS-CoV-2 and influenza A and B in congregate living settings by Yasmin Garad, Andreea A. Manea, Negin Pak, Lames Danok, Stefan Baral, Stefan Baral, Tom Dykstra, Danielle Kasperavicius, Sharon E. Straus, Sharon E. Straus, Christine Fahim, Christine Fahim

“…Five facilitators to implementation were described including: training and implementation support for staff at the CLSs; site-level implementation champions; access to materials to support testing; perceived advantages of simultaneous testing for COVID-19 and influenza; and the usability and functionality of the RAT testing device. Twenty implementation strategies were identified through implementation strategy mapping.DiscussionMultiplex RAT options can empower CLS staff to promptly identify and respond to viral respiratory outbreaks. …”
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