Natural variation of ClCCT promoter promotes flowering and dwarfing in adlay (Coix lacryma-jobi L.) by Jieliang Bao, Yanan Wang, Kuoshu Cui, Xiangdong Li, Hong Pan, Chaoyuan Shi, Xiang Yan, Jinglin Wang, Xiaotong Wang, Qing Dou, Xiaolong Dong, Yibing Yuan, Shufeng Zhou, Chao Guo

“…In this study, a major QTL associated with flowering time and plant height in adlay has been mapped and identified as ClCCT, a gene having a conserved function and regulatory pathway for inhibiting flowering time and increasing plant height in gramineous crops. …”
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Factors affecting the design of the management dashboard framework with an emphasis on the components of human resources productivity by Hassan Barmaki, Farshad Faezy Razi, Ehtesham Rashidi

“…It collects information gathered from all departments of the organization, which contains various sources related to various business functions. This information is combined and replicated by providing a user interface in the form of graphs, reports, visual indicators and alerting mechanisms. …”
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Personalised, GIS-based counselling to promote habitual walking in mobility-limited and chronically ill older adults: protocol of the MOBITEC-Routes randomised controlled trial by Timo Hinrichs, René Schilling, Alexandros Sofios, Denis Infanger, Luisa Prechtl, Nora Stauffer, Viviane Eichenberger, Eleftheria Giannouli, Taina Rantanen, Erja Portegijs, Corina Schuster-Amft, Anna Mai, Arno Schmidt-Trucksäss, Christina Röcke, Robert Weibel

“…Outcomes include walking (average steps per day; primary outcome), time spent lying, sitting, standing and stepping, physical function, life-space mobility, health-related quality of life, fall-related self-efficacy, active aging, as well as constructs of the Health Action Process Approach (HAPA) model (secondary outcomes). …”
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Leveraging a disulfidptosis-based signature to characterize heterogeneity and optimize treatment in multiple myeloma by Bingxin Zhang, Dong Zheng, Shuxia Zhu, Xinyi Zhang, Quanqiang Wang, Zhili Lin, Ziwei Zheng, Shujuan Zhou, Zixing Chen, Sisi Zheng, Enqing Lan, Luning Cui, Hansen Ying, Yu Zhang, Xuanru Lin, Qiang Zhuang, Honglan Qian, Xudong Hu, Yan Zhuang, Qianying Zhang, Zhouxiang Jin, Songfu Jiang, Yongyong Ma, Yongyong Ma, Yongyong Ma

“…We further explored genetic mutation mapping, protein-protein interactions, functional enrichment, drug sensitivity, drug prediction, and immune infiltration analysis among subtypes and risk subgroups. …”
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Opposing regulation of TNF responses by IFN-γ and a PGE2-cAMP axis that is apparent in rheumatoid and immune checkpoint inhibitor-induced arthritis human IL-1β+ macrophages by Upneet K Sokhi, Ruoxi Yuan, Bikash Mishra, Yurii Chinenov, Anvita Singaraju, Karmela K Chan, Anne Bass, Richard D Bell, Laura Donlin, Lionel B Ivashkiv

“…ICI-arthritis myeloid cells mapped primarily onto four previously defined RA synovial monocytic clusters, and TP genes were expressed in a manner suggestive of a new functional monocyte subset. …”
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Genome assembly and characterization of a complex zfBED-NLR gene-containing disease resistance locus in Carolina Gold Select rice with Nanopore sequencing. by Andrew C Read, Matthew J Moscou, Aleksey V Zimin, Geo Pertea, Rachel S Meyer, Michael D Purugganan, Jan E Leach, Lindsay R Triplett, Steven L Salzberg, Adam J Bogdanove

“…One of these has high sequence similarity to the cloned, functionally similar Xa1 gene. Both harbor an integrated zfBED domain, and the repeats within each protein are nearly perfect. …”
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HilD-regulated chemotaxis proteins contribute to Salmonella Typhimurium colonization in the gut by Kendal G. Cooper, Laszlo Kari, Audrey Chong, Naman Tandon, Kathleen Doran, Lidiane Gomes Da Silva, Diane C. Cockrell, Arden Baylink, Olivia Steele-Mortimer

“…We found that the conserved cysteine is required for McpA function in the mouse gut, thus demonstrating a virulence role for the CZB Zn2+-binding site during infection.IMPORTANCEThe gut-adapted bacterium Salmonella Typhimurium causes inflammatory diarrhea via a process that involves active invasion of intestinal epithelial cells, secretion of inflammatory molecules, and recruitment of immune cells. …”
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SEISMIC BELTS AND ZONES OF THE EARTH: FORMALIZATION OF NOTIONS, POSITIONS IN THE LITHOSPHERE, AND STRUCTURAL CONTROL by Semen I. Sherman, Olga G. Zlogodukhova

“…They can be variable due to changes in strike of local and regional faults which control seismicity and also due to various directions of zones of the recent lithospheric destruction.The Earth’s SBs and SZs are mapped. SBs and a number of most important SZs are briefly described. …”
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More than just mud: the importance of wallows to Javan rhino ecology and behaviour by Steven G. Wilson, Georgina Hockings, Jo-Anne M. Deretic, Salit Kark

“…We spatially mapped and recorded each wallow’s characteristics. …”
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Effector T cells under hypoxia have an altered transcriptome similar to tumor-stressed T cells found in non-responsive melanoma patients by Ahmad A Tarhini, Zhihua Chen, Dongliang Du, Joshua Davis, Justin C Boucher, Katarzyna A Rejniak, Jose A Guevara-Patino, Timothy I Shaw, Alyssa Obermayer, Mate Z Nagy, Lourdes B Plaza-Rojas, Elena Kostenko, Anna L Austin, Awino Maureiq E Ojwang'

“…To assess their function and transcriptional changes caused by hypoxia, effector T cells were generated and cultured under hypoxia (0.5% oxygen) or normoxia (21% oxygen). …”
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Early detection to improve outcome in people with undiagnosed psoriatic arthritis: the PROMPT research programme including RCT by Neil McHugh, Laura Bojke, Mel Brooke Turfrey, Rachel Charlton, Myka Ransom, Laura C Coates, Howard Collier, Claire Davies, Emma Dures, Philip Helliwell, Jana James, Anya Lissina, Vishnu B Madhok, Alison L Nightingale, Jonathan Packham, Catherine Smith, Eldon Spackman, Cerys Tassinari, William Tillett, Sarah T Brown

“…Surveillance for undiagnosed psoriatic arthritis generally detects mild cases as measured by physical function. Patients rate pain and fatigue as the most important outcomes. …”
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The comprehensive transcriptomic atlas of porcine immune tissues and the peripheral blood mononuclear cell (PBMC) immune dynamics reveal core immune genes by Qingyao Zhao, Jiahao Wang, Fuping Ma, Quanzhen Chen, Huatao Liu, Jinyan Yang, Siqian Chen, Yongjie Tang, Siyuan Mi, Lulu Wang, Xini Wang, Guohong Liu, Kai Xing, Ying Yu, Chuduan Wang

“…With the development of genomics technology, the combination of transcriptome, genetic variation, immune response, and QTL mapping data to illustrate the interactions between pathogen and host immune system, will be an effective tool for identification of disease resistance genes in pigs. …”
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Integrating plot-based methods for monitoring biodiversity in island habitats under the scope of BIODIVERSA + project BioMonI: Tree monitoring in Terceira, Tenerife and Réunion Isl... by Paulo Borges, Leila Morgado, Rosalina Gabriel, Rui Elias, Mirana Gauche, Claudine Ah-Peng, Rüdiger Otto, Lea de Nascimento, Dominique Strasberg, Nathaly Guerrero-Ramírez, Holger Kreft, José María Fernández-Palacios

“…Such data underpin the detection of subtle shifts in community composition, functional diversity and species distributions, which are critical for assessing the effectiveness of conservation actions and predicting future ecological scenarios.In summary, plot-based data are indispensable for targeted and effective biodiversity monitoring on islands. …”
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Tracing High-z Galaxies in X-Rays with JWST and Chandra by Aidan J. Kaminsky, Nico Cappelluti, Günther Hasinger, Alessandro Peca, Caitlin M. Casey, Giulia Cerini, Nicole E. Drakos, Andreas Faisst, Ghassem Gozaliasl, Olivier Ilbert, Jeyhan S. Kartaltepe, Alexander Kashlinsky, Anton M. Koekemoer, Henry Joy McCracken, Jason Rhodes, Brant E. Robertson, Marko Shuntov, Joseph Sterling

“…We fit the large-scale biasing of the IR sources producing the CIB as a function of z with results consistent with prior measurements, and place constraints on the CXB flux and biasing at low and high z . …”
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All‐in‐one perovskite memristor with tunable photoresponsivity by Guan‐Hua Dun, Yuan‐Yuan Li, Hai‐Nan Zhang, Fan Wu, Xi‐Chao Tan, Ken Qin, Yi‐Chu He, Ze‐Shu Wang, Yu‐Hao Wang, Tian Lu, Shi‐Wei Tian, Dan Xie, Jia‐Li Peng, Xiang‐Shun Geng, Xiao‐Tong Zhao, Jia‐He Zhang, Yu‐Han Zhao, Xiaoyu Wu, Ning‐Qin Deng, Zheng‐Qiang Zhu, Yan Li, Xian‐Zhu Liu, Xing Wu, Weida Hu, Peng Zhou, Yang Chai, Mario Lanza, He Tian, Yi Yang, Tian‐Ling Ren

“…Abstract Photoelectric memristors have shown great potential for future machine visions, via integrating sensing, memory, and computing (namely “all‐in‐one”) functions in a single device. However, their hard‐to‐tune photoresponse behavior necessitates extra function modules for signal encoding and modality conversion, impeding such integration. …”
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High-Throughput Indirect Monitoring of TORC1 Activation Using the pTOMAN-G Plasmid in Yeast by Melissa Gómez, Guilherme Rocha, Diego Ruiz, Claudio Martínez, Francisco Salinas, Eduardo Kessi-Pérez

“…The target of rapamycin complex 1 (TORC1) is a highly conserved protein complex whose primary function is to link nutrient availability to cell growth in eukaryotes, particularly nitrogen sources. …”
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Submillimeter and Mid-infrared Variability of Young Stellar Objects in the M17 H II Region by Zhiwei Chen, Doug Johnstone, Carlos Contreras Peña, Jeong-Eun Lee, Sheng-Yuan Liu, Gregory Herczeg, Steve Mairs, Geumsook Park, Kee-Tae Kim, Mi-Ryang Kim, Keping Qiu, Yao-Te Wang, Xu Zhang, Megan Reiter, The JCMT Transient Team

“…This mid-IR fractional variability as a function of evolutionary stage result is similar to what has previously been found for YSO variability within the Gould Belt and the intermediate-mass star formation region M17 SWex, though overall less variability is detected in M17 in submillimeter and mid-IR. …”
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Planning with self‑organised initiatives by Igor Tempels Moreno Pessôa

“…The cases of São Paulo, Rio de Janeiro and Brasília reveal a growth in the integration level from functional to symbolic, and even to community level in areas where these self-organised initiatives have been active. …”
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Prediction of stable structure and unique charge transfer in Li–Pt intermetallic compounds under pressure by Wenlin Xu, Dengjie Yan, Liguo Zhu, Yifei Wang, Lingxin Kong, Bin Yang, Baoqiang Xu

“…Bader charge analysis and electron localization function (ELF) mapping showed that the transition metal (Pt) atoms exhibit unusual oxidation states both under ambient and high pressure, and more electrons were localized on Pt as the Li content increased. …”
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The identification of adenylyl cyclase modulators as potential receptors for 6-nitrodopamine in human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes and their relevan... by Irene Cipollone, Irene Cipollone, Vittoria Monaco, Vittoria Monaco, José Britto-Júnior, Antonio Tiago Lima, Edson Antunes, Andre Sampaio Pupo, Ilaria Iacobucci, Ilaria Iacobucci, Flora Cozzolino, Flora Cozzolino, Maria Monti, Maria Monti, Silvia Parisi, Giuseppina Divisato, Emanuela Cascone, Alfonso De Simone, Angela Corvino, Ferdinando Fiorino, Francesco Frecentese, Vincenzo Santagada, Beatrice Severino, Rosa Sparaco, Pierfrancesco Cinque, Stefania Vertuccio, Giuseppe Caliendo, Gilberto De Nucci, Gilberto De Nucci, Gilberto De Nucci

“…A total of 817 proteins were generated, and following screening using UniProt “Retrieve/ID Mapping” function and Gene Ontology cellular component category, 124 proteins were identified as membrane proteins. …”
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