Energetische upgrading van Nederlandse Wederopbouw flats by Frits Schultheiss

“…Eliminating structural and building physical defects of the existing stock (Flat 1.0) is an opportunity for functional upgrading in the field of accessibility and social safety. …”
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Concept and Characteristic of Urban Landscape Layering, and Design Approach Towards Urban Regeneration by Jinyu ZHANG, Yuan XU, Yufan ZHU

“…Urban landscape evolves through a nonlinear process of accumulation, with physical structures, functions, and meanings continuously transforming. …”
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Preventing the transition from acute to chronic low back pain using home-based neuromodulation: protocol for a randomised, controlled study by Luke C Jenkins, James McAuley, Aidan Cashin, Tasha R Stanton, Amitabh Gupta, Rocco Cavaleri, Simon Summers, Keeley R McNally, Ariane Y Suhood, Daniel Thomson, Ghufran Alhassani

“…Mechanistic factors (potential mediators) of treatment effectiveness, including corticomotor organisation (transcranial magnetic stimulation mapping), somatosensory function, electroencephalography and affective-emotional characteristics, will also be assessed. …”
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The N-Terminal Region of the Transcription Factor E2F1 Contains a Novel Transactivation Domain and Recruits General Transcription Factor GTF2H2 by Lin Zhao, Rinka Nakajima, Yaxuan Zhou, Mashiro Shirasawa, Mariana Fikriyanti, Yuki Kamiya, Hiroyuki Toh, Hideyuki Komori, Ritsuko Iwanaga, Andrew P. Bradford, Hideo Nishitani, Kenta Kurayoshi, Keigo Araki, Kiyoshi Ohtani

“…In contrast, E2F1 contributes to tumor suppression by activating tumor suppressor genes, such as <i>ARF</i>, upon loss of pRB function, a major oncogenic change. The transactivation domain of E2F1 has previously been mapped to the C-terminal region. …”
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Dissecting the tumor microenvironment in primary breast angiosarcoma: insights from single-cell RNA sequencing by Peikai Ding, Shengbin Pei, Yi Zhai, Zheng Qu, Yazhe Yang, Xiaolong Feng, Qiang Liu, Xiangyu Wang, Wenxiang Zhang, Zhongzhao Wang, Xiangyi Kong, Jing Wang, Yi Fang

“…Cell populations were identified and classified into distinct cell types, and differential gene expression analysis was performed to explore key signaling pathways. Functional enrichment analysis was used to identify pathways related to tumor progression and immune evasion. …”
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The first generic tirzepatide GP30931: physicochemical and biological similarity to the reference drug by I. A. Lugovik, A. V. Babina, S. S. Arutyunyan, D. О. Ermolaeva, V. B. Saparova, T. N. Kobeleva, P. G. Zaikin, A. D. Mikushina, A. S. Bukatin, I. E. Eliseev, B. Ts. Zajchik, Y. S. Keruchenko, I. S. Ohrimenko, E. V. Bocharov, A. Kh. Taldaev, V. A. Lushpa, I. E. Makarenko, R. V. Drai

“…HPLC-MS and mapping confirmed identical mass (4,810.52 Da) and amino acid sequence. …”
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Correlation of Immune Parameters in Breast Cancer Patients Undergoing General Anesthesia: post-hoc Analysis of the TeMP Study by Kristina K. Kadantseva, Valery V. Subbotin, Mikhail Y. Yadgarov, Elizaveta M. Korolenok, Levan B. Berikashvili, Roman A. Akchulpanov, Nikolay S. Karnaukhov, Ksenia S. Korchagina, Polina I. Kukina, Oksana A. Svitich, Artem N. Kuzovlev, Anna S. Barmina, Valery V. Likhvantsev

“…More research is needed to better understand how different anesthetics affect immune function and the potential impact of anesthesia technique on long-term cancer outcomes.…”
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Contrasting effects of Si on high-temperature deformation behavior and room-temperature strength in V-microalloyed 10Mn-18Cr stainless steels by Atef Hamada, Ali Khosravifard, Khaled Elanany, Mahmoud Khedr, Anna Kisko, Matias Jaskari, Saad Ebied, Tarek Allam, Antti Järvenpää, Pentti Karjalainen

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The Association of Statin Therapy with Liver and Pancreatic Fat Fraction in Type 2 Diabetes Mellitus by Mehmet Akif Parlar, Hakan Mutlu, Betül Doğantekin, İsmail Serhat Musaoğlu, Nisa Demirboşnak Albayrakoğlu, Mustafa Lütfi Yavuz, Zehra Buşra Özbolat, Mustafa Kaplan

“…<b>Background/Objectives</b>: It has been shown that the use of statins in patients with type 2 diabetes mellitus (T2DM) worsens hyperglycemia and hemoglobin A1c levels but may help in the preservation of pancreatic β-cell function. The potential role of a high pancreatic fat fraction (PFF) in this process has not yet been clarified. …”
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Exploring the therapeutic potential and in vitro validation of baicalin for the treatment of triple-negative breast cancer by Yuan Ma, Ying Pan, Qiancheng Zhao, Chongheng Zhang, Haitao He, Lihua Pan, Jianling Jia, Aiping Shi, Yiming Yang, Wenfeng Zhang

“…GO analysis enriched a total of 2,526 Biological process, 105 Cellular component and 250 Molecular function related to the intersecting targets; KEGG analysis enriched a total of 128 signaling pathways related to the intersecting targets; molecular docking results and molecular dynamics studies found that baicalin was able to interact with MMP9, TNF-α, JAK2, PPARG, GSK3B, and other core targets of baicalin for the treatment of triple-negative breast, MMP9, TNF-α, and JAK2 target proteins, and had significant changes in the expression levels of the target proteins.ConclusionBaicalin inhibits the protein expression of MMP9, TNF-α and JAK2 and their related signaling pathways in the treatment of triple-negative breast cancer.…”
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Efficient toluene degradation using Bacillus subtilis biofilm-supported Mn–Ce/zeolite catalysts by Muhammad Zubair Mohsin, Ali Mohsin, Waqas Qamar Zaman, Xiaojuan Zhu, Xihua Zhao, Zain Abbas, Muhammad Hammad Hussain, Ali Shan, Salim-ur-Rehman, Muhammad Asif Nawaz, Rabia Omer, Yingping Zhuang, Meijin Guo, Jiaofang Huang

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Effects of dietary rumen-protected choline supplementation on genome-wide DNA methylation in mammary tissue from postpartum dairy cows by A. Celemin Sarmiento, B.J. Bradford, L.K. Mamedova, G. Zhou, K.A. Estes, T.H. Swartz

“…Future studies are needed to determine if methylation status of these genes affects cellular phenotype and function in the mammary gland as a potential mechanism behind the milk production responses due to dietary RPC supplementation.…”
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Digital health and mobile health: a bibliometric analysis of the 100 most cited papers and their contributing authors by Andy Wai Kan Yeung, Olena Litvinova, Nicola Luigi Bragazzi, Yousef Khader, Md. Mostafizur Rahman, Zafar Said, Robert S. H. Istepanian, Anastasios Koulaouzidis, Adeyemi Oladapo Aremu, James M. Flanagan, Navid Rabiee, Sheikh Mohammed Shariful Islam, Devesh Tewari, Ganesh Venkatachalam, Giustino Orlando, Josef Niebauer, Alexandros G. Georgakilas, Mohammad Reza Saeb, Dalibor Hrg, Yufei Yuan, Muhammad Ali Imran, Huanyu Cheng, Eliana B. Souto, Hari Prasad Devkota, Maurizio Angelo Leone, Jamballi G. Manjunatha, Nikolay T. Tzvetkov, Maima Matin, Olga Adamska, Sabine Völkl-Kernstock, Fabian Peter Hammerle, Farhan Bin Matin, Bodrun Naher Siddiquea, Dongdong Wang, Jivko Stoyanov, Jarosław Olav Horbańczuk, Magdalena Koszarska, Emil Parvanov, Iga Bartel, Artur Jóźwik, Natalia Ksepka, Bogumila Zima-Kulisiewicz, Björn Schuller, Gaurav Pandey, David Bates, Tien Yin Wong, Benjamin S. Glicksberg, Maciej Banach, Cyprian Tomasik, Seifedine Kadry, Stephen T. Wong, Ronan Lordan, Faisal A. Nawaz, Rajeev K. Singla, ArunSundar MohanaSundaram, Himel Mondal, Ayesha Juhi, Shaikat Mondal, Merisa Cenanovic, Aleksandra Zielińska, Christos Tsagkaris, Ronita De, Siva Sai Chandragiri, Robertas Damaševičius, Mugisha Nsengiyumva, Artur Stolarczyk, Okyaz Eminağa, Marco Cascella, Harald Willschke, Atanas G. Atanasov

“…The basic bibliographic data was directly extracted from WOSCC using its “Analyze” and “Create Citation Report” functions. The complete records of the top 100 papers were downloaded and imported into a bibliometric software called VOSviewer (version 1.6.19) to generate an author keyword map and author collaboration map. …”
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A neural network-based method for input parameter optimization of edge transport modeling utilizing experimental diagnostics by Y. Luo, S. Xu, Y. Liang, E. Wang, J. Cai, Y. Feng, D. Reiter, A. Knieps, S. Brezinsek, D. Harting, M. Krychowiak, D. Gradic, P. Ren, D. Zhang, Y. Gao, G. Fuchert, A. Pandey, M. Jakubowski, the W7-X Team

“…In this step, the FNN-predicted synthetic data are compared with the experimental data, and the likelihood function explicitly accounts for the measurement uncertainties of the selected diagnostics. …”
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THE PERIPHERY OF THE SPECTACLE: THE SPOILER AND THE TEASER / ПЕРИФЕРИЯ ЗРЕЛИЩА: СПОЙЛЕР И ТИЗЕР by KOZLOV EVGENY V. / КОЗЛОВ Е.В.

“…The redundancy of modern information endows the periphery of a work of art with a very important functional load. The valorization of intrigue and the tension of narrative associated with it are the most important elements of narration which generate interest and control the attention of the audience. …”
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Uso de retalho cutâneo para reconstrução nasal após ressecção neoplásica Use of skin flaps for nasal reconstruction after neoplastic resection by Francisco Felipe Laitano, Lourenço Frigeri Teixeira, Evandro José Siqueira, Gustavo Steffen Alvarez, Pedro Djacir Escobar Martins, Milton Paulo de Oliveira

“…Among the several available alternatives for covering the skin, skin flaps are the first cosmetic and functional choice. This study has 2 objectives: (1) to report the experiences of the Plastic Surgery Service of São Lucas Hospital of the Pontifical Catholic University of Rio Grande do Sul (Porto Alegre, RS, Brazil) in the reconstruction of nasal mass losses that resulted from tumor resection and (2) to describe the most commonly used skin flaps used for defect repair according to the anatomic subunit. …”
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Patient centered outcomes in stroke: utility-weighted modified Rankin Scale results in a community-based study by Carlos Delfino, Gabriel Cavada, Lorena Hoffmeister, Pablo Lavados, Pablo Lavados, Paula Muñoz Venturelli, Paula Muñoz Venturelli, Paula Muñoz Venturelli

“…We aimed to derive utility-weighted modified Rankin Scale (UW-mRS) values by mapping mRS functional status to EQ-5D-3L scores in a population-based cohort of stroke patients.MethodsThe UW-mRS was obtained by analyzing the EQ5-D-3 L and mRS scores at 180 days after any stroke in the ÑANDU study, a large prospective community-based study in Chile. …”
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A Strong Link Between Oceanographic Conditions and Zooplankton δ¹³C and δ¹⁵N Values in the San Jorge Gulf, Argentina by David Edgardo Galván, Manuela Funes, Flavio Emiliano Paparazzo, Virginia Alonso Roldán, Carla Derisio, Juan Pablo Pisoni, Brenda Temperoni, Daniela Alejandra del Valle, Valeria Segura, Seth D. Newsome

“…Maps of (baseline) δ¹³C and δ¹⁵N values of primary producers or consumers near the base of food webs provide crucial information for interpreting patterns in the isotopic composition of consumers that occupy higher trophic levels. …”
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Topographic associations of hyperreflective materials in diabetic retinopathy: a multimodal correlation with microvascular pathology, structural remodeling and systemic metabolic d... by Lan Zhou, Lan Zhou, Hongyan Sun, Hongyan Sun, Cunzi Li, Cunzi Li, Tianyi Luo, Tianyi Luo, Ting Meng, Xiaojun Wen, Zilin Chen, Yan Hu, Ming-Ming Yang, Ming-Ming Yang

“…Spatial mapping revealed predominant HRMs colocalization with IRMA territories (75.4% IRHFs, 89.5% ORHFs, 90.8% IRHE, 94% ORHE), while 19% of IRHFs and 8.7% of ORHFs overlapped NP zones. …”
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Re-use of Building Products in the Netherlands by Loriane Icibaci

“…The key findings in this segment were: Organizational The practice of reuse currently functions as an appendix of the demolition industry, bringing benefits as well as disadvantages. …”
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