Integrated oral microbiome and metabolome analysis unveils key biomarkers and functional pathway alterations in patients with acute myocardial infarction by Ikram Khan, Muhammad Irfan, Imran Khan, Xie Ping, Yu Xiaohui, Shengnan Lei, Tianzhu Song, Xiaodong Xie, Zhiqiang Li

“…The Streptococcus and Rothia genera, as well as 9(R)-HODE, 20-HETE ethanolamide, and 5,6 EET metabolites, were identified as potential biomarkers, achieving an area under the curve of 0.82–0.88. Functional pathway analysis demonstrated significant upregulation in key metabolic pathways, including the Citrate Cycle (TCA cycle), Pyruvate metabolism, and Glucagon signaling pathways, which exhibited strong correlations with established clinical markers of AMI.ConclusionThis integrative analysis underscores the diagnostic potential of oral microbiome-metabolome interactions in AMI and unveils key mechanistic pathways for guiding future therapeutic interventions.…”
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Integrative Korean Medicine for Pain and Functional Recovery in Lumbar Transverse Process Fractures: A Case Report and Literature Review by Ji-Sun Kim, Gyu-Bin Lee, Hong-Wook Choi, Do-Young Kim, Dong-Jin Kim, Dong-Ju Yoon, Ye-Rim Yun, Ji-Sung Yeum, Ik-Jun Cho

“…The transverse processes function as essential attachment points for the muscles and ligaments surrounding the spine, and transverse process fractures (TPF) are commonly observed in trauma patients, such as those involved in traffic accidents. …”

Integrating Functional and Phylogenetic Diversity to Assess Bird Community Assembly Along the Major Rivers of Hainan Island, South China by Sidan Lin, Wei Liang

“…The patterns of community assembly were subsequently assessed by integrating functional and phylogenetic diversity, whereas environmental factors and interspecific competition intensity were incorporated to determine whether community assembly in these rivers is driven by environmental filtering or interspecific competition. …”
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METHOD FOR SOLVING ILL-POSED PROBLEMS FOR DIFFERENTIAL EQUATIONS WITH APPROXIMATELY GIVEN FUNCTIONS BASED ON THE REPRESENTATION OF THE SOLUTION OF INTEGRAL EQUATIONS by Igor' Eduardovich Naats, Victoria Igorevna Naats, Roman Andreyevich Ryskalenko

“…This uses a machine approximation of functions and their derivatives corresponding singular integrals and regularization method convergence of the sequence of approximate solutions, which implemented the so-called generalized inverse operators. …”
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Hayai-Annotation: A functional gene prediction tool that integrates orthologs and gene ontology for network analysis in plant species by Andrea Ghelfi, Sachiko Isobe

“…This approach aims to improve the visualization of conserved biological processes and functions, highlight species-specific adaptations, and enhance the ability to infer the functions of uncharacterized genes by comparing edge patterns across species. …”
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Resistance training, cognitive function and the elderly: an integrative review / Treinamento resistido, função cognitiva e idosos: revisão integrativa by Marckson da Silva Paula, Neilson Duarte Gomes, Estélio Henrique Martin Dantas

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Using modified two-dimensional block-pulse functions for the numerical solution of nonlinear two-dimensional volterra integral equations by F. Mirzaee, Elham Hadadiyan

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Integrative multi-omics and machine learning reveal critical functions of proliferating cells in prognosis and personalized treatment of lung adenocarcinoma by Shun Wang, Dingtao Hu, Ruohuang Wang, Jie Huang, Baoqing Wang

“…High- and low-SPRS groups exhibited different biological functions and immune cell infiltration in the TIME. …”
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Analyzing the function of metaverse technology in the retention and absorption of knowledge using the integrated approach of interpretive structural modeling and structural equations by Seyed Mojtaba Hosseinibamakan, Hajar Soleymanizadeh, Mehran Ziaeian

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Feasibility of Smartphone-Based Exercise Training Integrated with Functional Electrical Stimulation After Stroke (SETS): A Preliminary Study by Rudri Purohit, Juan Pablo Appelgren-Gonzalez, Gonzalo Varas-Diaz, Shuaijie Wang, Matias Hosiasson, Felipe Covarrubias-Escudero, Tanvi Bhatt

“…Participants also showed pre-post improvements in all measures of gait and balance function (<i>p</i> < 0.05). Integrating SETS and FES is feasible and yields short-term gains in gait and balance function among OAwS. …”
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An Improved Wavelet Soft-Threshold Function Integrated with SVMD Dual-Parameter Joint Denoising for Ancient Building Deformation Monitoring by Jiaxing Zhao, Houzeng Han, Yang Deng, Youqiang Dong, Jian Wang, Wenjin Chen

“…In deformation monitoring, complex environments, such as seismic excitation, often lead to noise during signal acquisition and transmission processing. This study integrates sequential variational mode decomposition (SVMD), a dual-parameter (DP) model, and an improved wavelet threshold function (IWT), presenting a denoising method termed SVMD-DP-IWT. …”
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Some Properties for Adjustable Entropy Function Method and Its Application to Power Systems Dynamic Economic Dispatch with Wind Integrated by Yaming Ren

“…Then, for solving this problem, we take advantage of the adjustable entropy function method to replace of aggregate function method. …”
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The integrative genomic and functional immunological analyses of colorectal cancer initiating cells to modulate stemness properties and the susceptibility to immune responses by Issam Tout, Salim Bougarn, Mohammed Toufiq, Neha Gopinath, Ola Hussein, Abbirami Sathappan, Evonne Chin-Smith, Fazulur Rehaman, Rebecca Mathew, Lisa Mathew, Kun Wang, Li Liu, Abdulrahman Salhab, Oleksandr Soloviov, Sara Tomei, Waseem Hasan, Sahar Da’as, Yosra Bejaoui, Nady El Hajj, Karama Makni Maalej, Said Dermime, Kakil Rasul, Paolo Dellabona, Giulia Casorati, Alice Turdo, Matilde Todaro, Giorgio Stassi, Soldano Ferrone, Xinhui Wang, Cristina Maccalli

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Temporal cortex activation reveals emotional multisensory integration in preschoolers: An fNIRS study by Yahui Xue, Huan Deng, Mengnan Lu, Mingjia Chen, Yichao Fu

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Integral evaluation of the formation of adaptive capacity of the children's body under the condition of systematic specific physical load by Hanna Latina, Iryna Kalynychenko, Olena Tkachuk, Oksana Danysko, Tetyana Ivanova

“…The following blocks share the second place: “athlete efficiency” and “functional state of the cardiovascular and respiratory systems”. …”
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Some properties of Urysohn-Stieltjes integral operators by Józef Banaś

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Insulin resistance: vascular function and exercise by Moon-Hyon Hwang, Sewon Lee

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Conscious and unconscious perception of pitch shifts in auditory feedback during vocalization: Behavioral functions and event-related potential correlates by Daniel Suchý, Roozbeh Behroozmand, Henry Railo

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Mapping variants in thyroid hormone transporter MCT8 to disease severity by genomic, phenotypic, functional, structural and deep learning integration by Stefan Groeneweg, Ferdy S. van Geest, Mariano Martín, Mafalda Dias, Jonathan Frazer, Carolina Medina-Gomez, Rosalie B. T. M. Sterenborg, Hao Wang, Anna Dolcetta-Capuzzo, Linda J. de Rooij, Alexander Teumer, Ayhan Abaci, Erica L. T. van den Akker, Gautam P. Ambegaonkar, Christine M. Armour, Iiuliu Bacos, Priyanka Bakhtiani, Diana Barca, Andrew J. Bauer, Sjoerd A. A. van den Berg, Amanda van den Berge, Enrico Bertini, Ingrid M. van Beynum, Nicola Brunetti-Pierri, Doris Brunner, Marco Cappa, Gerarda Cappuccio, Barbara Castellotti, Claudia Castiglioni, Krishna Chatterjee, Alexander Chesover, Peter Christian, Jet Coenen-van der Spek, Irenaeus F. M. de Coo, Regis Coutant, Dana Craiu, Patricia Crock, Christian DeGoede, Korcan Demir, Cheyenne Dewey, Alice Dica, Paul Dimitri, Marjolein H. G. Dremmen, Rachana Dubey, Anina Enderli, Jan Fairchild, Jonathan Gallichan, Luigi Garibaldi, Belinda George, Evelien F. Gevers, Erin Greenup, Annette Hackenberg, Zita Halász, Bianka Heinrich, Anna C. Hurst, Tony Huynh, Amber R. Isaza, Anna Klosowska, Marieke M. van der Knoop, Daniel Konrad, David A. Koolen, Heiko Krude, Abhishek Kulkarni, Alexander Laemmle, Stephen H. LaFranchi, Amy Lawson-Yuen, Jan Lebl, Selmar Leeuwenburgh, Michaela Linder-Lucht, Anna López Martí, Cláudia F. Lorea, Charles M. Lourenço, Roelineke J. Lunsing, Greta Lyons, Jana Krenek Malikova, Edna E. Mancilla, Kenneth L. McCormick, Anne McGowan, Veronica Mericq, Felipe Monti Lora, Carla Moran, Katalin E. Muller, Lindsey E. Nicol, Isabelle Oliver-Petit, Laura Paone, Praveen G. Paul, Michel Polak, Francesco Porta, Fabiano O. Poswar, Christina Reinauer, Klara Rozenkova, Rowen Seckold, Tuba Seven Menevse, Peter Simm, Anna Simon, Yogen Singh, Marco Spada, Milou A. M. Stals, Merel T. Stegenga, Athanasia Stoupa, Gopinath M. Subramanian, Lilla Szeifert, Davide Tonduti, Serap Turan, Joel Vanderniet, Adri van der Walt, Jean-Louis Wémeau, Anne-Marie van Wermeskerken, Jolanta Wierzba, Marie-Claire Y. de Wit, Nicole I. Wolf, Michael Wurm, Federica Zibordi, Amnon Zung, Nitash Zwaveling-Soonawala, Fernando Rivadeneira, Marcel E. Meima, Debora S. Marks, Juan P. Nicola, Chi-Hua Chen, Marco Medici, W. Edward Visser

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Engineered extracellular vesicles for delivering functional Cas9/gRNA to eliminate hepatitis B virus cccDNA and integration by Wanjia Zeng, Liwei Zheng, Yukun Li, Jing Yang, Tianhao Mao, Jing Zhang, Yanna Liu, Jing Ning, Ting Zhang, Hongxin Huang, Xiangmei Chen, Fengmin Lu

“…In conclusion, engineered EVs could successfully mediate functional CRISPR/Cas9 delivery both in vitro and in vivo, leading to the clearance of episomal cccDNA and integrated viral DNA fragments, and providing a novel therapeutic approach for curing chronic HBV infection.…”
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