El proceso de enseñanza-aprendizaje, enfoque sistémico de sus componentes en el deporte escolar (The teaching-learning process, a systemic approach to its components in school spor... by Orlando Llamas-Cruz, Teresa de Jesús Barreras Villavelázquez, Jaime Salvador Dorantes-González, Ma. Concepción Soto Valenzuela, Wilberth Velducea Velducea, Ramón Alfonso González Rivas

“…The TLP understood as a system and applied in a systematic way allows strengthening the pedagogical-didactic competence of the physical educator or the sports coach, even the physical rehabilitator of the sport, as it allows carrying out his functions from a scientific point of view in order to ensure the deployment of his personality and guide the student or user to direct his own biopsychosocial development and his constructive critical thinking from the reflection-action. …”
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Multi-omics analysis reveals the role of ribosome biogenesis in malignant clear cell renal cell carcinoma and the development of a machine learning-based prognostic model by Zhouzhou Xie, Zhouzhou Xie, Shansen Peng, Shansen Peng, Jiongming Wang, Jiongming Wang, Yueting Huang, Yueting Huang, Xiaoqi Zhou, Xiaoqi Zhou, Guihao Zhang, Guihao Zhang, Huiming Jiang, Huiming Jiang, Kaihua Zhong, Kaihua Zhong, Lingsong Feng, Lingsong Feng, Nanhui Chen, Nanhui Chen

“…However, its role in ccRCC pathogenesis and prognosis remains poorly defined.MethodsWe integrated bulk RNA sequencing, single-cell RNA sequencing, and spatial transcriptomics sequencing data to dissect the biological functions and clinical relevance of Ribosis-related genes in ccRCC. …”
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Contrastive learning with transformer for adverse endpoint prediction in patients on DAPT post-coronary stent implantation by Fang Li, Zenan Sun, Ahmed abdelhameed, Tiehang Duan, Laila Rasmy, Xinyue Hu, Jianping He, Yifang Dang, Jingna Feng, Jianfu Li, Yichen Wang, Tianchen Lyu, Naomi Braun, Si Pham, Michael Gharacholou, DeLisa Fairweather, Degui Zhi, Jiang Bian, Cui Tao

“…Meanwhile, the model was holistically optimized using multiple loss functions, to ensure the predicted results closely align with the ground-truth values from various perspectives. …”
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Optical and electron microscopy imaging of model circulating tumour cells by Марина Оленчук, Григорій Монастирський, Олена Гнатюк, А. Бойзен, Ч. Чжан, Галина Солянік, Денис Колесник, Сергій Карахім, Галина Довбешко

“…Objectives: This study aimed to visualize Lewis lung carcinoma (LLC) cells cultured under de-adhesive conditions using various microscopy techniques for their characterization and to examine the cancer cells' structure and functionality. The goal was to evaluate each method's individual capabilities and combined strengths in revealing cellular morphology, internal structure, and nanoparticle interactions. …”
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Moonlighting activity of threonine synthase in cyanobacterial cell death by Wonjae Kim, Yongjun Son, Yerim Park, Minkyung Kim, Reagan Lee, Keu Eun San Kim, Sung Jae Shin, Woojun Park

“…PyMoL-based structural prediction and in vitro biochemical assays unveiled the moonlighting functions of ThrC in both threonine biosynthesis and deamination. …”
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Comprehensive mathematical modeling of age-dependent oocyte quality and quantity for predicting live birth rate by Toshio Sujino, Tatsuyuki Ogawa, Akira Komiya, Akira Komiya, Makiko Tajima, Yuko Takayanagi, Yurie Nako, Hayata Nakajo, Kenichiro Hiraoka, Isao Tamura, Hidetoshi Yamashita, Kiyotaka Kawai

“…In the first stage, medically meaningful model functions were selected, and curve fitting was performed using weighted nonlinear least-squares regression to quantify age-related changes in oocyte quality and quantity. …”
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Ecological Concrete-Based Modular System for Heavy Metal Removal in Riparian Transition Zones: Design, Optimization and Performance Evaluation by Guangbing Liu, Da Ke, Hasnain Moavia, Chen Ling, Yanhong Zhang, Yu Shen

“…Through systematic optimization, we developed a C25-grade ecological concrete module (100 mm × 100 mm × 100 mm) with a specialized cavity design (φ61 mm × H60 mm) that achieves optimal balance between structural integrity (20–30 MPa compressive strength) and environmental functionality (>15% porosity, >1 × 10⁻⁴ cm s⁻¹ permeability). …”
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Multivariate geostatistical methods for analysing the contribution of urban lakes and neighbouring greenery to mitigating PM2.5 under stressor indicators by Han Liu, Wenyu An, Arkadiusz Przybysz, Dingyi Hao, Yimei Sun, Junze Song, Jiayi Sui, Jiahan Sun, Chunyang Zhu

“…Maintaining the ecological integrity and functionality of ecosystems is one of the major challenges faced in the sustainable management of natural capital. …”
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Deciphering the anticoccidial mechanism of Qinghao Changshan formula through network pharmacology and molecular docking by Dong Tian, Hui Fu, Hongxia Tao, Miaolan Li, Qinghua Zhang, Weidong Deng

“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were conducted to explore relevant biological functions and pathways. Molecular docking was used to validate interactions between selected active compounds (isorhamnetin, kaempferol, quercetin) and key targets (epidermal growth factor receptor [EGFR], estrogen receptor 1 [ESR1], progesterone receptor [PGR]). …”
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Urban Tree Canopy Mapping and Analysis Using Iterative Annotation Method and Deep Learning: A Case Study in Beijing by Yulong Ding, Ximin Cui, Zhengchao Chen, Zeqing Wang, Debao Yuan, Xiang Meng, Xuan Yang, Yue Xu, Xiangyu Tian

“…Urban trees have significant ecological and social functions, and generating urban tree canopy (UTC) maps is an effective method for understanding their distribution. …”
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Multi-level analysis of gut microbiome extracellular vesicles-host interaction reveals a connection to gut-brain axis signaling by Walid Mottawea, Basit Yousuf, Salma Sultan, Tamer Ahmed, JuDong Yeo, Nico Hüttmann, Yingxi Li, Nour Elhouda Bouhlel, Hebatoallah Hassan, Xu Zhang, Zoran Minic, Riadh Hammami

“…Furthermore, MEVs were able to traverse the intestinal barriers and reach distal organs, including the brain, thereby potentially influencing brain functionality and contributing to mental and behavior.…”
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The Effect of “Carvacrol” on Ischemia-Reperfusion Injury in the Skeletal Muscles of Rats by Barış Mardin, Abdullah Özer, Başak Koçak, Ayşegül Küçük, Mustafa Hakan Zor, Şaban Cem Sezen, Mustafa Kavutçu, Mustafa Arslan, Gürsel Levent Oktar

“…In surgical procedures characterized by frequent occurrences of ischemia-reperfusion (I/R), such as transplant and cardiovascular surgery, it is crucial to prioritize the preservation of tissue integrity and mitigation of associated damage. In this study, we formulated a hypothesis suggesting that carvacrol (Car), an aromatic hydrocarbon present in some plant species, might decrease I/R injury by implication of its antioxidant, anti-apoptotic, and anti-inflammatory functions. …”
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Identification of novel molecular subtypes and construction of a prognostic signature via multi-omics analysis and machine learning in lung adenocarcinoma by Ke Ma, Jie Xu, Jie Xu, Congyue Wang, Congyue Wang, Xu Cao, Xu Cao, Wenjie Yu, Jingjing Xi, Xuan Zhang, Jiamin Zhan, Yang Liu, Aoyang Yu, Aoyang Yu, Shuhan Liu, Yanhua Liu, Yanhua Liu, Chong Chen, Chong Chen, Xiaoli Mai, Xiaoli Mai

“…Single-cell RNA-sequencing (scRNA-seq) data were integrated to characterize subtype-specific immune microenvironments. …”
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AI-driven pharmacovigilance: Enhancing adverse drug reaction detection with deep learning and NLP by Dr. Bharti Khemani, Dr. Sachin Malave, Samyukta Shinde, Mandvi Shukla, Razzaq Shikalgar, Harshita Talwar

“…BERT and GPT, were also employed to provide the functionality of textual interactions over medical data. • Performance metrics such as accuracy, precision, recall, and F1-score were systematically applied to evaluate each model’s performance. …”
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The Mission of the Neocatechumenal Way in Times of Covid-19 by Bogumił Gacka

“…The argument  ̶  the secularization hypothesis  ̶  is that as education spreads, as incomes rise, and as the state takes over many functions of the church, people turn away from religion. …”
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Examining the Influence of the Shadow Economy on the Performance of Financial Markets and the Banking Sector in BRICS Countries: A Panel SUR Approach by Jaber Hasan Mhejir, Samad Hekmati Farid, Ali Reza Zadeh, Yousef Mohammad Zadeh

“…Controlling and reducing the size of informal economic sectors can enhance the functioning of financial markets and improve banks’ operational status. …”
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Graphical representation of global water models by H. Müller Schmied, H. Müller Schmied, S. N. Gosling, M. Garnsworthy, L. Müller, C.-E. Telteu, A. K. Ahmed, L. S. Andersen, J. Boulange, P. Burek, J. Chang, H. Chen, L. Gudmundsson, M. Grillakis, L. Guillaumot, N. Hanasaki, A. Koutroulis, R. Kumar, G. Leng, J. Liu, J. Liu, J. Liu, X. Liu, I. Menke, I. Menke, V. Mishra, V. Mishra, Y. Pokhrel, O. Rakovec, O. Rakovec, L. Samaniego, L. Samaniego, Y. Satoh, H. L. Shah, M. Smilovic, T. Stacke, E. Sutanudjaja, W. Thiery, A. Tsilimigkras, Y. Wada, N. Wanders, T. Yokohata

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Application of a Hybrid Model Based on CEEMDAN and IMSA in Water Quality Prediction by GUO Li-jin, WU Hao-tian

“…IMSA’s performance was validated using benchmark functions (Rosenbrock for unimodal, Michalewicz for multimodal), confirming improved global search and convergence precision. …”
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Design and Evaluation of Real-Time Data Storage and Signal Processing in a Long-Range Distributed Acoustic Sensing (DAS) Using Cloud-Based Services by Abdusomad Nur, Yonas Muanenda

“…We employ the DynamoDB functionality of Amazon Web Services (AWS), which allows highly expandable storage capacity with latency of access of a few tens of milliseconds. …”
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Impact of pediatric tracheostomy on family caregivers’ burden and quality of life: a systematic review and meta-analysis by Win Thu Aung, Natasha Yixuan Ong, Shina Qing Chun Yeo, Nur Syahindah Binti Juhari, Gwyneth Kong, Nicole-Ann Lim, Zubair Amin, Zubair Amin, Yvonne Peng Mei Ng, Yvonne Peng Mei Ng

“…Seven studies (469 caregivers) using Pediatric Quality of Life Family Integrated Module underwent meta-analysis. The pooled mean total family impact score, parental health-related QOL, family functioning score were 70.29 [95% CI, 61.20–79.37], 69.27 [95% CI, 60.88–77.67], and 72.96 [95% CI, 65.92–80.00] respectively. …”
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