Bioinspired surface functionalization of biodegradable mesoporous silica nanoparticles for enhanced lubrication and drug release by Xiaowei Mao, Kexin Chen, Yanlong Zhao, Chunrong Xiong, Jing Luo, Yuguang Wang, Bo Wang, Hongyu Zhang

“…Furthermore, the dual-functional nanoparticles were biocompatible and effectively reduced the expression levels of two inflammation factors such as interleukin-1β (IL-1β) and interleukin-6 (IL-6). …”
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Landscape of mobile genetic elements and their functional cargo across the gastrointestinal tract microbiomes in ruminants by Yijun Tang, Pengchao Zhan, Yingjian Wu, Tao Zhang, Di Yin, Yunlong Gao, Yueying Yu, Shengnan Qiu, Jiaqi Zhao, Xue Zhang, Zhe Ma, Yanting Chen, Liang Zhao, Shengyong Mao, Jinhu Huang, Wei-Hua Chen, Jinxin Liu

“…This study systematically profiles MGE distribution and functionality across gastrointestinal regions in multiple ruminant species to advance our understanding of microbial adaptation. …”
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Genetic and functional characterization of inherited complex chromosomal rearrangements in a family with multisystem anomalies by He Fang, Stephen M. Eacker, Yu Wu, Whitney Neufeld-Kaiser, Mercy Laurino, Siobán Keel, Marshall S. Horwitz, Yajuan J. Liu

“…This underscores the value of novel cytogenetic and genomic techniques in deciphering complex genome rearrangements and the significance of integrative genomic analysis and functional characterization in understanding clinical phenotypes.…”
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A Surrogate Piecewise Linear Loss Function for Contextual Stochastic Linear Programs in Transport by Qi Hong, Mo Jia, Xuecheng Tian, Zhiyuan Liu, Shuaian Wang

“…To address this limitation, inspired by the smart predict-then-optimize framework, we introduce a novel tunable piecewise linear loss function (PLLF). Rather than directly incorporating decision loss into the learning objective based on specific problem, PLLF serves as a general feedback mechanism that guides the prediction model based on the structure and sensitivity of the downstream optimization task. …”
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The gut microbiome and metabolome in kidney transplant recipients with normal and moderately decreased kidney function by Yang Lan, Duo Wang, Jiayang He, Hongji Yang, Yifu Hou, Wenjia Di, Hailian Wang, Xiangwei Luo, Liang Wei

“…The enrichment of gut microbial function in CKD-T is correlated with the expression of gut metabolites.Conclusion Gut microbiome and metabolites in the progression of CKD-T display some unique distribution and expression characteristics. …”
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Humeral retroversion, shoulder range of motion, and functional mobility in striking martial arts athletes by Bartosz Sieger, Bartosz Wilczyński, Bożena Sztuka, Maciej Biały, Katarzyna Zorena

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Assessing the multi-scale predictive ability of ecosystem functional attributes for species distribution modelling. by Salvador Arenas-Castro, João Gonçalves, Paulo Alves, Domingo Alcaraz-Segura, João P Honrado

“…In this regard, satellite-derived Ecosystem Functional Attributes (EFAs) offer a more integrative and quicker evaluation of ecosystem responses to environmental drivers and changes than climate and structural or compositional landscape attributes. …”
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Changes in objective characteristics in brain electrical activity in newborns as a function of birth weight by Anastasiya E. Runnova, Yuliya A. Zhuravleva, Evgeniy N. Egorov, Evgeniya E. Drozhdeva

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Association between cannabis use and brain structure and function: an observational and Mendelian randomisation study by Anya Topiwala, Klaus Ebmeier, Saba Ishrat, Daniel F Levey, Joel Gelernter

“…Bidirectional two-sample Mendelian randomisation analyses were used to investigate potential causal relationships.Findings Cannabis use was associated with multiple measures of brain structure and function. Participants with a history of cannabis use had poorer white matter integrity, as assessed by lower fractional anisotropy and higher mean diffusivity in the genu of the corpus callosum, as well as weaker resting-state functional connectivity in brain regions underlying the default mode and central executive networks. …”
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Long-Term Follow-Up of Vestibular Function in Cochlear-Implanted Teenagers and Young Adults by Niki Karpeta, Eva Karltorp, Luca Verrecchia, Maoli Duan

“…Background: Vestibular function implements head position regulation and body spatial navigation. …”
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The Effect of Eight Weeks Pilates Training on Functional Indicators and Postural Abnormalities in Older Men by Keyvan Hejazi, Mohammad Roki, Aref Makrami Mayvan, Azizeh Toghdori

“…This study investigates the effect of eight weeks of Pilates exercise training on functional indicators and postural abnormalities in older men. …”
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Immunotherapy against tau fragment diminishes AD pathology, improving synaptic function and cognition by Jie Xiang, Zhengjiang Qian, Ye Xi, Yanuo Wei, Guangxing Wang, Xia Liu, Zhi-Hao Wang, Zhentao Zhang, Shengxi Wu, Keqiang Ye

“…We conducted chronic intraperitoneal administration of the antibody to evaluate its effects on tau aggregation, synaptic integrity, and cognitive function. Neuropathological changes, synaptic plasticity (through electrophysiology), and behavioral outcomes were analyzed alongside Aβ pathology and neuroinflammation in 3xTg mice. …”
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Therapeutic reduction of neurocan in murine intracerebral hemorrhage lesions promotes oligodendrogenesis and functional recovery by Hongmin Li, Samira Ghorbani, Olayinka Oladosu, Ping Zhang, Frank Visser, Jeff Dunn, Yunyan Zhang, Chang-Chun Ling, V. Wee Yong, Mengzhou Xue

“…Difluorosamine shifted the degeneration-associated functional state of microglia/macrophages in ICH towards a regulatory phenotype. …”
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Evaluation of the immobilized enzymes function in soil remediation following polycyclic aromatic hydrocarbon contamination by Babar Hussain, Hongqing Zhu, Chunyu Xiang, Luo Mengfei, Bowei Zhu, Shibin Liu, Hui Ma, Shengyan Pu

“…However, the practical application is limited by its instability and ease to loss function under harsh environmental conditions such as pH, temperature, and edaphic stress etc. …”
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Drivers of Structural and Functional Resilience Following Extreme Fires in Boreal Forests of Northeast China by Jianyu Yao, Xiaoyang Kong, Lei Fang, Zhaohan Huo, Yanbo Peng, Zile Han, Shilong Ren, Jinyue Chen, Xinfeng Wang, Qiao Wang

“…Ongoing climate change has intensified fire disturbances in boreal forests globally, posing significant risks to forest ecosystem structure and function, with the potential to trigger major regime shifts. …”
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Molecular mechanisms explaining sex-specific functional connectivity changes in chronic insomnia disorder by Liyong Yu, Zhifu Shen, Wei Wei, Zeyang Dou, Yucai Luo, Daijie Hu, Wenting Lin, Guangli Zhao, Xiaojuan Hong, Siyi Yu

“…Abstract Background This study investigates the hypothesis that chronic insomnia disorder (CID) is characterized by sex-specific changes in resting-state functional connectivity (rsFC), with certain molecular mechanisms potentially influencing CID's pathophysiology by altering rsFC in relevant networks. …”
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Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development by Li Xu, Yuxin Cui, Jiaxin Xing, Qili Mi, Zhixing Wang, Xujing Wang, Wanli Zeng, Haiying Xiang, Jiarui Jiang, Lele Deng, Kunmiao Wang, Jiangtao Yang, Qian Gao

“…To date, although the molecular functions of genes involved in vitamin B6 biosynthesis, including Pdx1, Pdx2, Pdx3, and Sos4, have been reported in various plants, no studies have yet explored the functions of NtPDX1 and NtPDX2 in tobacco. …”
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Is functional brain connectivity atypical in autism? A systematic review of EEG and MEG studies. by Christian O'Reilly, John D Lewis, Mayada Elsabbagh

“…Of note, abnormal lateralization in ASD, specifically an elevated left-over-right EEG and MEG functional connectivity ratio, has been also reported consistently across studies.…”
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Functional Orientation and Development Prospect of Natural Gas Power Generation in New Power System by Guanjun FU, Fuqiang ZHANG, Peng XIA, Junshu FENG, Jinfang ZHANG

“…Based on the model calculation results, the paper establishes quantitative indicators to evaluate the functional role of gas-fired electricity in new power systems and analyzes its functional role in clean electricity supply, power balance, and peak shaving balance in the future. …”
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The impact of warm-up with the volleyveilig approach on upper extremity function in female volleyball players by Adibeh Baharmast, Parisa Sedaghati, Somayeh Ahmadabadi

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