Impact of adjuvant trastuzumab therapy and its discontinuation on cardiac function and mortality in patients with early-stage breast cancer: An analysis based on the Japanese Receipt Claim Database by Keiko Miyazato, Hiroshi Ohtsu, Akihiko Shimomura, Naohiro Yonemoto, Chikako Shimizu, Kazuhiro Sase, Shinichiro Ueda

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The impact of plant growth-promoting bacteria on the functional and thermodynamic traits of Aptenia cordifolia and Carpobrotus edulis under recycled water irrigation in external green wall conditions by Mansoure Jozay, Hossein Zarei, Sarah Khorasaninejad, Taghi Miri

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Impact of telehealth-based therapeutic exercise on pain, functional performance and dynamic knee valgus in young adult females with patellofemoral pain: a randomised controlled trial by Patcharin Nilmart, Mantana Vongsirinavarat, Pimpaka Khawsuwan, Kiatrada Chumthong, Russareeta Tadein, Dwi Rosella Komalasari

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Impact of exercise training on exercise tolerance, cardiac function and quality of life in individuals with heart failure and preserved ejection fraction: a systematic review and meta-analysis by Hu Li, Yingxue Liu, Yu Liu, Zhichao Xu, Pengchao Pan, Lijun Zeng

“…There were no significant differences between high-intensity interval training (HIIT) and moderate continuous training (MCT) in improving exercise tolerance, cardiac function, or quality of life. Conclusion Exercise training effectively enhances exercise tolerance and physical quality of life in patients with HFpEF, without significantly impacting cardiac function parameters. …”
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Role of Low-Cost Negative Pressure Dressing in the Management of Sacral Pressure Injuries and its Impact on Functional Recovery in Neuro-rehabilitation: A Retrospective Case Series by Arvind Kumar Sharma, Kumari Sunaina, Ivanah P Nongrum, Satyasheel Singh Asthana

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Impact of Vitamin D₃ Functionalization on the Osteogenic Capacity of Bioinspired 3D Scaffolds Based on Ce-Doped Bioactive Glass and Spongia Agaricina by Ana-Maria Seciu-Grama, Sorana Elena Lazăr, Simona Petrescu, Oana Cătălina Mocioiu, Oana Crăciunescu, Irina Atkinson

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Impact of Low-Load High-Volume Initial Sets vs. Traditional High-Load Low-Volume Bench Press Protocols on Functional and Structural Adaptations in Powerlifters by Francisco J. González-Alcázar, Pablo Jiménez-Martínez, Carlos Alix-Fages, Alberto Ruiz-Ariza, Rafael A. Casuso, Jesús Varela-Goicoechea, Amador García-Ramos, Agustín Jerez-Martínez

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Evaluating the impact of drought and water restrictions on agricultural production in irrigated areas through crop water productivity functions and a remote sensing-based evapotranspiration model by Joaquim Bellvert, Magí Pamies-Sans, Jaume Casadesús, Joan Girona

“…Since crop yield is closely linked to the water used (crop actual evapotranspiration, ETcact), this study proposes a novel approach based on using crop water productivity functions and a remote sensing-based surface energy balance model to spatially estimate ETcact. …”
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The impact of a short-term high-fat diet on coagulation function in a mouse model and its role in exacerbating concanavalin A-induced liver injury by Eri Nanizawa, Yuki Tamaki, Tomiko Yakura, Shun Otsuka, Naoyuki Hatayama, Munekazu Naito

“…These patients are at a higher risk of cardiovascular events and thromboembolism. However, the direct impact of high-fat diet (HFD), a cause of MASLD, on liver coagulation function is not well understood. …”
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Pathogenic single nucleotide polymorphisms in RhoA gene: Insights into structural and functional impacts on RhoA-PLD1 interaction through molecular dynamics simulation by Mahbub Hasan, Md. Nayem Sarker, Tazkia Jabin, Saifuddin Sarker, Shamim Ahmed, Mohammad Abdullah-Al-Shoeb, Tanvir Hossain

“…Consequently, the single nucleotide polymorphisms (SNPs) within the RhoA gene, especially deleterious genetic variations, are crucial to study to forecast structural alteration and their functional impacts in light of disease onset. In this comprehensive study, we employed a range of computational tools to screen the deleterious SNPs of RhoA from 207 nonsynonymous SNPs (nsSNPs). …”
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Probing the functional impact of sequence variation on p53-DNA interactions using a novel microsphere assay for protein-DNA binding with human cell extracts. by Maher A Noureddine, Daniel Menendez, Michelle R Campbell, Omari J Bandele, Monica M Horvath, Xuting Wang, Gary S Pittman, Brian N Chorley, Michael A Resnick, Douglas A Bell

“…This microsphere assay system utilizes biologically meaningful cell extracts in a multiplexed, quantitative, in vitro format that provides a powerful experimental tool for elucidating the functional impact of sequence polymorphism and protein variation on protein/DNA binding in transcriptional networks.…”
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Impact of Cognitive VR vs. Traditional Training on Emotional Self-Efficacy and Cognitive Function in Patients with Multiple Sclerosis: A Retrospective Study Focusing on Gender Differences by Maria Grazia Maggio, Alessandra Benenati, Federica Impellizzeri, Amelia Rizzo, Martina Barbera, Antonino Cannavò, Vera Gregoli, Giovanni Morone, Francesco Chirico, Angelo Quartarone, Rocco Salvatore Calabrò

“…The purpose of this study is to evaluate the impact of VR-based training on emotional self-efficacy in multiple sclerosis (MS) patients and examine its association with cognitive function improvement. …”
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Impact of electronic cigarette ever use on lung function in adults aged 45–85: a cross-sectional analysis from the Canadian Longitudinal Study on Aging by MyLinh Duong, Parminder Raina, Divya Joshi, Susan Kirkland

“…Objective To describe the sociodemographic characteristics associated with e-cigarette ever use and to examine the impact of e-cigarette ever use on lung function impairment in an ageing population.Design A cross-sectional analysis of data from the Canadian Longitudinal Study on Aging.Setting A national stratified sample of 44 817 adults living in Canadian provinces.Participants Respondents included participants aged 45–85 and residing in the community in Canadian provinces.Outcome measures The Global Lung Function Initiative normative values for forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), forced expiratory ratio (FEV1/FVC) appropriate for age, sex, height and ethnicity were used to interpret the severity of lung function impairment. …”
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Impact of maternal high‐fat diet on offspring gut microbiota during short‐term high‐fat diet exposure in mice by Henry A. Paz, Lasya Buddha, Ying Zhong, James D. Sikes, Umesh D. Wankhade

“…Sex‐specific differences were observed in the gut microbial composition and predicted functional potential. Furthermore, the influence of maternal diet on bacterial community structure and functional potential varied depending on postnatal diet. …”
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Study on the Impact of Hormone Therapy for Prostate Cancer on the Quality of Life and the Psycho-Relational Sphere of Patients: ProQoL by Francesca Cappuccio, Carlo Buonerba, Luca Scafuri, Rossella Di Trolio, Pasquale Dolce, Serena Orsola Trabucco, Filomena Erbetta, Elvira Tulimieri, Antonella Sciscio, Concetta Ingenito, Antonio Verde, Giuseppe Di Lorenzo

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Tourism and Sustainable Regional Development in Romania and France: an Approach from the Perspective of New Economic Geography by Gabriela Carmen Pascariu, Ramona Tiganasu

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Impact of Transchalcone on Neurological Outcomes in Cerebral Ischemia-reperfusion Injury in Rat: Role of AMP-activated Protein Kinase-mitochondrial Signaling Pathways by Xiuyun Xue, Jingjing Du, Shaik Althaf Hussain, Narendra Maddu, Jing Xiong

“…The present study investigated the potential protective effects of TCH in a rat model of CIR, focusing on its impact on the activation of AMP-activated protein kinase (AMPK) pathway, mitochondrial function, and inflammatory mediators. …”
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How low-abundance amphibians shape functional diversity across tropical forest succession stages? by Fabio Zabala-Forero, Angela M. Cortés-Gómez, Nicolás Urbina-Cardona

“…Trait-based ecology provides key insights into the impact of these species on functional diversity metrics, particularly in landscapes undergoing ecological succession after land abandonment in tropical forests. …”
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Cognitive and social functions of craniopharyngioma and germ cell tumor differ in patients with and without apathy by Ami Tabata, Keita Ueda, Katsutsugu Umeda, Takeshi Funaki, Tsukasa Ueno, Yohei Mineharu, Masahiro Tanji, Takayuki Kikuchi, Misa Komaki, Susumu Miyamoto, Toshiya Murai, Yoshiki Arakawa

“…Therefore, this study investigated patients with diencephalon tumors to assess the impact of apathy on their neurocognitive, social cognitive, and social functions. …”
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The Impact of Physical Activity and Screen Time on Motor Creativity in Kindergarteners by Rafat Ghanamah

“…Background/Objectives: Motor creativity and physical activity are essential to early childhood development, impacting physical, cognitive, and socio-emotional development. …”
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