STAT2/SLC27A3/PINK1-Mediated Mitophagy Remodeling Lipid Metabolism Contributes to Pazopanib Resistance in Clear Cell Renal Cell Carcinoma by Dingheng Lu, Yuxiao Li, Xinyang Niu, Jiazhu Sun, Weitao Zhan, Yuchen Shi, Kai Yu, Suyuelin Huang, Xiaoyan Liu, Liping Xie, Xueyou Ma, Ben Liu

“…Methods: 786-O to pazopanib resistance was induced by gradient increase of concentration, and the genes related to lipid metabolism were screened by RNA sequencing. …”
Get full text

Species Diversity, Biomass Production and Carbon Sequestration Potential in the Protected Area of Uttarakhand, India by Geetanjali Upadhyay, Lalit M. Tewari, Ashish Tewari, Naveen Chandra Pandey, Sheetal Koranga, Zishan Ahmad Wani, Geeta Tewari, Ravi K. Chaturvedi

“…Ecosystem functioning and management are primarily concerned with addressing climate change and biodiversity loss, which are closely linked to carbon stock and species diversity. …”
Get full text

Welgelegen by Gerdy Alette VERSCHUURE-STUIP

“…The word strictly means “well positioned” in modern Dutch but the descriptions show it can be interpreted better as well-functioning and entertaining.  Location and composition factors The most important physical factors and motives, the answer to the first research question, were: a favorable location in the landscape (i.e., fertile soil, water, height differences, landscape gradients); a position along good and “entertaining” infrastructural connections (land and waterways); and a favorable relation with the city (view of and mental link to a city, accessibility and travel time). …”
Get full text

Diversity and Distribution of Fungi in the Marine Sediments of Zhanjiang Bay, China by Menghan Gao, Bihong Liu, Jianming Li, Yunyan Deng, Yulei Zhang, Ning Zhang, Feng Li, Changling Li, Xianghu Huang, Zhangxi Hu

“…Additionally, the FUNGuild database was employed to assess the potential functional traits of fungi. A total of 1242 ASV sequences, affiliated to 144 genera and five phyla, were identified. …”
Get full text

Symptom-specific gut microbial and metabolic profiles in ADHD reveal SCFA deficiency as a Key pathogenic mechanism by Xinyue Wang, Ning Wang, Teng Gao, Yunfan Zhang, Zhao Fu, Yilu Zhao, Yujingwen Huang, Xiangyu Zheng, Xuping Gao, Lin Lu, Li Yang

“…The redundancy analysis identified ADHD symptoms as environmental gradients and explained the changes in beta diversity (F = 1.345, pFDR = 0.015). …”
Get full text

The influence of urban and agricultural landscape contexts on forest diversity and structure across ecoregions by John Paul Schmit, Lea R. Johnson, Matthew Baker, Lindsay Darling, Robert Fahey, Dexter H. Locke, Anita T. Morzillo, Nancy F. Sonti, Tara L. E. Trammell, Myla F. J. Aronson, Michelle L. Johnson

“…Abstract Forest patches in urban landscapes make outsized contributions to biodiversity, ecosystem function, and human health and well‐being. However, urbanization can alter environmental conditions that underpin forest health. …”
Get full text

Development mechanism and practical significance of deep coalbed methane (coal rock gas) infiltration and displacement by Lihong ZHOU, Xia YAN, Hongtao LIU, Xianyue XIONG, Feng WANG, Shuguang LI, Jiyuan ZHANG, Chuanqing LIU, Xiong HU, Pu YUAN, Qianli MA, Xueguang ZHU

“…At a 5 MPa gas-liquid pressure differential, fracturing fluids displaced 70.84% of free gas and competitively desorbed 10.42% of adsorbed gas, suggesting higher displacement efficiency under elevated pressure gradients. Nanopore displacement dynamics: Molecular dynamics simulations revealed piston-like displacement in nanopores under high-pressure gradients, converting 97.8% of adsorbed methane into free gas. …”
Get full text

Asymmetrical Time-Lagged Response of Vegetation to Drought and Extreme Precipitation Across China by Wenli Lai, Yongxiang Chen, Jie Zhang, Huai Yang

“…In this study, a study area was chosen in China to analyze the lagged response relationship between normalized difference vegetation index (NDVI) and extreme precipitation/drought from 1982 to 2015. A logistical function was applied to explain the increase in NDVI with mean annual precipitation in nine sub-regions, and the inflection point of precipitation was found to be very close to the threshold value for separating arid or humid regions. …”
Get full text

Transcatheter edge‐to‐edge repair of atrial secondary mitral regurgitation positively influences atrial remodelling by Aniela Petrescu, Martin Geyer, Julian Andres Gelves Meza, Omar Hahad, Tobias Ruf, Valeria Maria deLuca, Lukas Hobohm, Theresa Gößler, Felix Kreidel, Philipp Lurz, Ralph Stephan vonBardeleben

“…Evidence of the effect of transcatheter edge‐to‐edge repair (TEER) on left atrial (LA) anatomy and function, especially reverse remodelling (LARR), is still sparse. …”
Get full text

Spatially varying parameters improve carbon cycle modeling in the Amazon rainforest with ORCHIDEE r8849 by L. Zhu, L. Zhu, L. Zhu, L. Zhu, P. Ciais, Y. Yao, D. Goll, S. Luyssaert, I. Martínez Cano, A. Fendrich, A. Fendrich, L. Li, H. Yang, S. Saatchi, W. Li, W. Li

“…Current dynamic global vegetation models (DGVMs), which use one or two plant functional types for tropical rainforests, fail to capture observed biomass and mortality gradients in this region, raising concerns about their ability to predict forest responses to global change drivers. …”
Get full text

Integrating plot-based methods for monitoring biodiversity in island habitats under the scope of BIODIVERSA + project BioMonI: Tree monitoring in Terceira, Tenerife and Réunion Isl... by Paulo Borges, Leila Morgado, Rosalina Gabriel, Rui Elias, Mirana Gauche, Claudine Ah-Peng, Rüdiger Otto, Lea de Nascimento, Dominique Strasberg, Nathaly Guerrero-Ramírez, Holger Kreft, José María Fernández-Palacios

“…Initiatives like the Global Island Monitoring Scheme (GIMS) highlight the value of permanent plots in capturing ecological gradients and anthropogenic disturbance patterns. Such data underpin the detection of subtle shifts in community composition, functional diversity and species distributions, which are critical for assessing the effectiveness of conservation actions and predicting future ecological scenarios.In summary, plot-based data are indispensable for targeted and effective biodiversity monitoring on islands. …”
Get full text

Measurement report: Long-term assessment of primary and secondary organic aerosols in the Shanghai megacity throughout China's Clean Air actions since 2010 by H. Yu, Y. Chang, L. Cheng, Y. Duan, J. Hu

“…Potential sources from distant regions were analyzed using the potential source contribution function (PSCF), indicating that the geographical potential source area is concentrated near the middle and lower Yangtze River.…”
Get full text

Responses of field-grown maize to different soil types, water regimes, and contrasting vapor pressure deficit by T. H. Nguyen, T. Gaiser, J. Vanderborght, A. Schnepf, F. Bauer, A. Klotzsche, L. Lärm, H. Hüging, F. Ewert, F. Ewert

“…Future improvements in soil–crop models in simulating gas exchange and crop growth should further emphasize the role of soil textures on stomatal function, dynamic root growth, and plant hydraulic system together with aboveground leaf area adjustments.…”
Get full text

Physiological and Gene Expression Responses of Crassostrea ariakensis to Salinity Stress by Miaomiao YANG, Sudong XIA, Zhihong LIU, Xiujun SUN, Liqing ZHOU, Peizhen MA, Zhuanzhuan LI, Biao WU

“…Oysters are keystone species in marine ecosystems and essential for restoring ecological function and maintaining biodiversity maintenance. …”
Get full text

Random Finite Element Analysis and Random Factor response Mechanism for Geocell-reinforced Soil Retaining Walls by ZHANG Bingbing, SONG Fei

“…Further, by comparing the stress cloud maps of the deterministic model and the random field model, it is found that the deterministic model presents regular stress gradients and smooth contour transitions, while the random field model exhibits significant irregular stress distribution characteristics. …”
Get full text

Effect of climate on traits of dominant and rare tree species in the world’s forests by Iris Hordijk, Lourens Poorter, Jingjing Liang, Peter B. Reich, Sergio de-Miguel, Gert-Jan Nabuurs, Javier G. P. Gamarra, Han Y. H. Chen, Mo Zhou, Susan K. Wiser, Hans Pretzsch, Alain Paquette, Nicolas Picard, Bruno Hérault, Jean-Francois Bastin, Giorgio Alberti, Meinrad Abegg, Yves C. Adou Yao, Angelica M. Almeyda Zambrano, Braulio V. Alvarado, Esteban Alvarez-Davila, Patricia Alvarez-Loayza, Luciana F. Alves, Iêda Amaral, Christian Ammer, Clara Antón-Fernández, Alejandro Araujo-Murakami, Luzmila Arroyo, Valerio Avitabile, Gerardo A. Aymard C, Timothy Baker, Olaf Banki, Jorcely Barroso, Meredith L. Bastian, Luca Birigazzi, Philippe Birnbaum, Robert Bitariho, Pascal Boeckx, Frans Bongers, Olivier Bouriaud, Pedro H. S. Brancalion, Susanne Brandl, Francis Q. Brearley, Roel Brienen, Eben N. Broadbent, Helge Bruelheide, Roberto Cazzolla Gatti, Ricardo G. Cesar, Goran Cesljar, Robin L. Chazdon, Chelsea Chisholm, Emil Cienciala, Connie J. Clark, David B. Clark, Gabriel Colletta, David Coomes, Fernando Cornejo Valverde, Jose J. Corral-Rivas, Philip Crim, Jonathan Cumming, Selvadurai Dayanandan, André L. de Gasper, Mathieu Decuyper, Géraldine Derroire, Ben DeVries, Ilija Djordjevic, Aurélie Dourdain, Jiri Dolezal, Nestor Laurier Engone Obiang, Brian Enquist, Teresa Eyre, Adandé Belarmain Fandohan, Tom M. Fayle, Leandro V. Ferreira, Ted R. Feldpausch, Leena Finér, Markus Fischer, Christine Fletcher, Lorenzo Frizzera, Damiano Gianelle, Henry B. Glick, David Harris, Andrew Hector, Andreas Hemp, John Herbohn, Annika Hillers, Eurídice N. Honorio Coronado, Cang Hui, Hyunkook Cho, Thomas Ibanez, Ilbin Jung, Nobuo Imai, Andrzej M. Jagodzinski, Bogdan Jaroszewicz, Vivian Johannsen, Carlos A. Joly, Tommaso Jucker, Viktor Karminov, Kuswata Kartawinata, Elizabeth Kearsley, David Kenfack, Deborah Kennard, Sebastian Kepfer-Rojas, Gunnar Keppel, Mohammed Latif Khan, Timothy Killeen, Hyun Seok Kim, Kanehiro Kitayama, Michael Köhl, Henn Korjus, Florian Kraxner, Diana Laarmann, Mait Lang, Simon Lewis, Huicui Lu, Natalia Lukina, Brian Maitner, Yadvinder Malhi, Eric Marcon, Beatriz Schwantes Marimon, Ben Hur Marimon-Junior, Andrew Robert Marshall, Emanuel Martin, Olga Martynenko, Jorge A. Meave, Omar Melo-Cruz, Casimiro Mendoza, Cory Merow, Stanislaw Miscicki, Abel Monteagudo Mendoza, Vanessa Moreno, Sharif A. Mukul, Philip Mundhenk, Maria G. Nava-Miranda, David Neill, Victor Neldner, Radovan Nevenic, Michael Ngugi, Pascal A. Niklaus, Jacek Oleksyn, Petr Ontikov, Edgar Ortiz-Malavasi, Yude Pan, Alexander Parada-Gutierrez, Elena Parfenova, Minjee Park, Marc Parren, Narayanaswamy Parthasarathy, Pablo L. Peri, Sebastian Pfautsch, Oliver L. Phillips, Maria Teresa Piedade, Daniel Piotto, Nigel C. A. Pitman, Martina Pollastrini, Irina Polo, Axel Dalberg Poulsen, John R. Poulsen, Freddy Ramirez Arevalo, Zorayda Restrepo-Correa, Mirco Rodeghiero, Samir Rolim, Anand Roopsind, Francesco Rovero, Ervan Rutishauser, Purabi Saikia, Christian Salas-Eljatib, Peter Schall, Dmitry Schepaschenko, Michael Scherer-Lorenzen, Bernhard Schmid, Jochen Schöngart, Eric B. Searle, Vladimír Seben, Federico Selvi, Josep M. Serra-Diaz, Douglas Sheil, Anatoly Shvidenko, Javier Silva-Espejo, Marcos Silveira, James Singh, Plinio Sist, Ferry Slik, Bonaventure Sonké, Alexandre F. Souza, Hans ter Steege, Krzysztof Stereńczak, Jens-Christian Svenning, Miroslav Svoboda, Ben Swanepoel, Natalia Targhetta, Nadja Tchebakova, Raquel Thomas, Elena Tikhonova, Peter Umunay, Vladimir Usoltsev, Renato Valencia, Fernando Valladares, Fons van der Plas, Tran Van Do, Michael E. Van Nuland, Rodolfo Vasquez Martinez, Hans Verbeeck, Helder Viana, Alexander C. Vibrans, Simone Vieira, Klaus von Gadow, Hua-Feng Wang, James Watson, Gijsbert D. A. Werner, Florian Wittmann, Verginia Wortel, Roderick Zagt, Tomasz Zawila-Niedzwiecki, Chunyu Zhang, Xiuhai Zhao, Zhi-Xin Zhu, Irie Casimir Zo-Bi, Daniel S. Maynard, Thomas W. Crowther

“…The extent to which traits of dominant and rare tree species differ remains untested across a broad environmental range, limiting our understanding of how species traits and the environment shape forest functional composition. We use a global dataset of tree composition of >22,000 forest plots and 11 traits of 1663 tree species to ask how locally dominant and rare species differ in their trait values, and how these differences are driven by climatic gradients in temperature and water availability in forest biomes across the globe. …”
Get full text

Identification and bioinformatics analysis of PIN gene family in chrysan-themum plants(菊属植物PIN基因家族的鉴定及生物信息学分析) by 刘波(LIU Bo), 刘欣宇(LIU Xinyu), 李骏倬(LI Junzhuo), 武晓云(WU Xiaoyun), 卢敏(LU Min), 王佳颖(WANG Jiaying), 戴思兰(DAI Silan)

“…The above results provide a theoretical basis for the subsequent study of the function of the PIN gene in chrysanthemum plants. . …”
Get full text

Impact of short-term aircraft noise on cardiovascular disease risk in the area surrounding London Heathrow airport: the RISTANCO epidemiological study by Xiangpu Gong, Nicole Itzkowitz, Calvin Jephcote, Kathryn Adams, Glory O Atilola, John Gulliver, Marta Blangiardo, Anna Hansell

“…Are there interactions with factors such as age, gender, ethnicity and deprivation that may function as effect modifiers? Is there variability in risk estimates between areas with consistent patterns of noise exposure versus those with changing patterns of noise exposure? …”
Get full text

On a Nonsmooth Vector Optimization Problem with Generalized Cone Invexity by Hehua Jiao, Sanyang Liu

“…By using Clarke’s generalized gradients we consider a nonsmooth vector optimization problem with cone constraints and introduce some generalized cone-invex functions called K-α-generalized invex, K-α-nonsmooth invex, and other related functions. …”
Get full text

Private Stochastic Optimization with Large Worst-Case Lipschitz Parameter by Andrew Lowy, Meisam Razaviyayn

“… We study differentially private (DP) stochastic optimization (SO) with loss functions whose worst-case Lipschitz parameter over all data points may be huge or infinite. …”
Get full text