Enhanced porcine gut barrier functioning and reduced inflammation from a combination of seaweed  bioactives by Meike A. Bouwhuis, Irene H. G. Nooijen, Evita van de Steeg, Shane O’Connell

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Homonymy in English Language and Means of Its Representation (on Example of Functional Words <i>what</i> and <i>very</i>) by T. S. Ignatyeva, N. A. Antonova

“…The novelty of the study is seen in the fact that by the example of certain functional words ( what and very ), the authors have shown that they can be homonymous words, and their appearance in the language is not the result of conversion, but the result of splitting of multifunctional words expressing relationships.…”
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Functional evaluation of novel compound heterozygous variants in SLC12A3 of Gitelman syndrome by Na Wang, Yuanxing Yang, Xiong Tian, Hongjun Fu, Shuaishuai Chen, Juping Du, Mengyi Xu, Haixia He, Bo Shen, Jiaqin Xu

“…The prediction of mutant protein indicated that p.E240K and p.L892P altered protein’s secondary and three-dimensional (3D) structure and stability. Functional experiments revealed decreased protein expression and Na+ uptake activity caused by these two variants, especially the p.L892P variant. …”
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Neuroanatomical and functional substrates of the short video addiction and its association with brain transcriptomic and cellular architecture by Yuanyuan Gao, Ying Hu, Jinlian Wang, Chang Liu, Hohjin Im, Weipeng Jin, Wenwei Zhu, Wei Ge, Guang Zhao, Qiong Yao, Pinchun Wang, Manman Zhang, Xin Niu, Qinghua He, Qiang Wang

“…We investigated the neuroanatomical and functional substrates of SVA symptoms, alongside brain transcriptomic and cellular characteristics, using Inter-Subject Representational Similarity Analysis (IS-RSA) and transcriptomic approaches. …”
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Molecular Analysis of <i>Aggregatibacter actinomycetemcomitans</i> ApiA, a Multi-Functional Protein by Sera Jacob, Luciana Gusmao, Dipti Godboley, Senthil Kumar Velusamy, Nisha George, Helen Schreiner, Carla Cugini, Daniel H. Fine

“…<i>Aggregatibacter actinomycetemcomitans</i> ApiA is a trimeric autotransporter outer membrane protein (Omp) that participates in multiple functions, enabling <i>A. actinomycetemcomitans</i> to adapt to a variety of environments. …”
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Biological function of RNA-binding proteins in myocardial infarction: a potential emerging therapeutic limelight by Chenyang Jin, Yutong Ye, Longzhe Gao, Zikan Zhong, Changzuan Zhou, Xiaoyu Wu, Xudong Li, Genqing Zhou, Songwen Chen, Yong Wei, Lidong Cai, Shaowen Liu, Juan Xu

“…RBPs, as key regulators coordinating cell differentiation and tissue homeostasis, exhibit specific functions in gene transcription, RNA modification and processing, and post-transcriptional gene expression. …”
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Total darkness activated intestinal clock system and improved intestinal barrier function in growing rabbits by Yao Li, Jiali Chen, Fuchang Li, Lei Liu

“…Abstract The aim of study was to investigate the effects of dark environment on production performance, intestinal barrier function and clock-related gene expression in rabbits. …”
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A facile strategy to synthesize poly(methyl methacrylate)-co-polyisobutylene via a deoxygenation reaction by Kankanok Longkaew, Philippe Daniel, Taweechai Amornsakchai, Thanchanok Ratvijitvech, Pranee Phinyocheep

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Green's function approach to interacting lattice polaritons and optical nonlinearities in subwavelength arrays of quantum emitters by Simon Panyella Pedersen, Georg M. Bruun, Thomas Pohl

“…While most studies have thus far relied on numerical simulations, we describe here a diagrammatic Green's function approach that permits analytical investigations of nonlinear processes. …”
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Single-boson exchange formulation of the Schwinger-Dyson equation and its application to the functional renormalization group by Miriam Patricolo, Marcel Gievers, Kilian Fraboulet, Aiman Al-Eryani, Sarah Heinzelmann, Pietro M. Bonetti, Alessandro Toschi, Demetrio Vilardi, Sabine Andergassen

“…The simple form of the single-boson exchange SDE, involving only the bosonic propagator and the fermion-boson vertex, but not the rest function, allows for an efficient numerical implementation. …”
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Do β-Defensins and Other Antimicrobial Peptides Play a Role in Neuroimmune Function and Neurodegeneration? by Wesley M. Williams, Rudy J. Castellani, Aaron Weinberg, George Perry, Mark A. Smith

“…Herein supporting evidence is presented for the hypothesis that neuropathological changes associated with chronic disease conditions of the CNS involve abnormal expression and regulatory function of specific antimicrobial peptides. …”
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Identification of galectin-9 and its antibacterial function in Yellow River carp (Cyprinus carpio haematopterus) by Li Wang, Li Wang, Li Wang, Yuanyuan Hu, Xudong Li, Ziyan Zhang, Nan Wang, Limin Chao, Chengfei Li, Pei Gao, Jinyou Ma, Jinyou Ma, Lei Wang, Xiaojing Xia, Xiaojing Xia

“…IntroductionGalectin-9 is a β-galactoside-binding lectin that functions as a critical pattern recognition receptor (PRR) in the host immune system, initiating immune defense responses by recognizing and binding to pathogen-associated molecular patterns (PAMPs) on the surface of microorganisms. …”
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Molecular characterization and functional analysis of CYP315 A1 in ovarian development in Macrobrachium nipponense by Sufei Jiang, Wenyi Zhang, Jufeng Jiang, Mengying Zhang, Jisheng Wang, Yiwei Xiong, Hui Qiao, Hongtuo Fu

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Novel Trimethoprim-Based Metal Complexes and Nanoparticle Functionalization: Synthesis, Structural Analysis, and Anticancer Properties by Abbas M. Abbas, Hossam H. Nasrallah, A. Aboelmagd, W. Christopher Boyd, Haitham Kalil, Adel S. Orabi

“…We then prepared metal complexes of this derivative with Cu(II), Co(II), Ni(II), Ag(I), and Zn(II) and functionalized them with ZnO and Au nanoparticles. Their structures were confirmed through ¹H NMR, mass spectrometry, FTIR, conductivity, thermal analysis, magnetic susceptibility, X-ray diffraction, UV-Vis spectroscopy, and TEM, revealing octahedral geometries for all complexes. …”
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Aqueous extracts of Portulaca oleracea L. alleviate atopic dermatitis by restoring skin barrier function by Haobin Wei, Zhang Chen, Zhang Chen, Wenjie Lai, Wenjie Lai, Wenxian Wang, Xiqing Bian, Xiqing Bian, Limin Zhang, Xinzhi Li, Xinzhi Li

“…The phosphorylation of JAK1, signal transducer and activator of transcription (STAT)3, and STAT6 in keratinocytes and skin were analyzed by Western blotting.ResultsIn DNCB-sensitized mice, the PO hydrogel ameliorated skin lesions, lowered symptom scores, and reduced epidermal thickness by suppressing proinflammatory factor generation, oxidative stress, and the expression of CD4+. The PO hydrogel promoted the expression of caspase-14 and filaggrin, thereby helping restore skin barrier function in AD. …”
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Two Types of Distributed CFAR Detection Based on Weighting Functions in Fusion Center for Weibull Clutter by Amir Zaimbashi

“…Moreover, for the Weibull clutter, the expression of the weighting functions, based on ML and OS CFAR processors in local detectors, is obtained. …”
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Beyond Static Tethering at Membrane Contact Sites: Structural Dynamics and Functional Implications of VAP Proteins by Takashi S. Kodama, Kyoko Furuita, Chojiro Kojima

“…However, the detailed mechanism of its functional expression remains unclear. In this review, we quantitatively discuss the structural dynamics of the entire molecule, including intrinsically disordered regions and intramolecular and intermolecular interactions, focusing on the vertebrate VAP paralogs VAPA and VAPB. …”
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Using functional annotation for the empirical determination of Bayes Factors for genome-wide association study analysis. by Jo Knight, Michael R Barnes, Gerome Breen, Michael E Weale

“…One promising strategy to help separate these is to use functional annotations for prioritisation of variants for follow-up. …”
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The Functional Polymorphisms of miR-146a Are Associated with Susceptibility to Severe Sepsis in the Chinese Population by Yiming Shao, Jia Li, Yujie Cai, Yuliu Xie, Guoda Ma, You Li, Yanyan Chen, Gen Liu, Bin Zhao, Lili Cui, Keshen Li

“…In addition, we confirmed that the two SNPs rs2910164 and rs57095329 could functionally affect the miR-146a expression levels and the reduction of miR146a was accompanied with the upregulation of the expression levels of TRAF-6 and IRAK-1 in severe sepsis patients. …”
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Meta-Analysis of Acupuncture on Physical and Activity Participation Related Functions of Children with Autism Spectrum Disorders by CHEN Qiang, KAN Mengfan, JIANG Xiaoyu, LIU Huifen, SUN Wenyu, BI Hongyan

“…Meta-analysis results showed that, (1) In terms of physical function: compared with the control group, the emotional function score of the experimental group was significantly higher [<italic>SMD</italic>=0.76, 95% <italic>CI</italic> (0.50, 1.03), <italic>P</italic>&lt;0.000 01]; sleep function score was significantly lower [<italic>MD</italic>=-6.74, 95% <italic>CI</italic> (-8.31, -5.17), <italic>P</italic>&lt;0.000 01], and cognitive function score was significantly higher [<italic>SMD</italic>=1.14, 95% <italic>CI</italic> (0.85, 1.42), <italic>P</italic>&lt;0.000 01]. (2) In terms of activity participation: compared with the control group, the score of healthy behavior in the experimental group was significantly lower [<italic>MD</italic>=-2.63, 95% <italic>CI</italic> (-3.68, -1.59), <italic>P</italic>&lt;0.000 01], the score of expression ability was significantly higher [<italic>SMD</italic>=0.81, 95% <italic>CI</italic> (0.55, 1.08), <italic>P</italic>&lt;0.000 01], and the score of social ability was significantly lower [<italic>SMD</italic>=-0.70, 95% <italic>CI</italic> (-0.88, -0.53), <italic>P</italic>&lt;0.000 01].ConclusionAcupuncture can significantly improve the physical and activity participation functions such as emotion, sleep, cognition, social interaction, and language expression of children with ASD, which is recommended for further clinical application.…”
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