Differential Change in Retina Structure and Function in Children and Adolescents with Drusens of the Optic Nerve Disk by A. G. Shchuko, D. Yu. Samsonov, S. I. Zhukova, T. N. Iureva, I. M. Mikhalevich, A. V. Grigorieva, Yu. S. Samsonova

“…Central vision in patients with drusens of the optic nerve disc is reduced rarely, and their diagnosis is reduced to ascertaining of the fact of having drusen without taking into account the structural and functional changes in the visual system.Purpose of the work: to identify the pattern of changes in visual functions in children and adolescents with druses of the optic nerve disk, the development and addition of classification criteria.Patients and methods. 45 children with drusens were examined, a comprehensive analysis of the visual system included a standard ophthalmological examination, a comprehensive study of visual system with ultrasound scanning, OCT and OCTA, standard automated and pulsarperimetry.Based on the results of the cluster analysis, a graph of the distribution of patients into three groups (control group and two clinical groups) was constructed, and the structural and functional state of the visual system was analyzed. …”
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A genome-wide association study of pulmonary function measures in the Framingham Heart Study. by Jemma B Wilk, Ting-Hsu Chen, Daniel J Gottlieb, Robert E Walter, Michael W Nagle, Brian J Brandler, Richard H Myers, Ingrid B Borecki, Edwin K Silverman, Scott T Weiss, George T O'Connor

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Highly conserved ion binding sites are not all functionally relevant in mouse KCC4 by Lisa Becker, Jens Hausmann, Rieke Wellpott, Anna-Maria Hartmann, Anna-Maria Hartmann

“…IntroductionThe potassium chloride cotransporter 4 (KCC4) is expressed in various tissues and plays an important role in distal renal acidification and hearing development. …”
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Functional dynamics analysis of endophytic microbial communities during Amorphophallus muelleri seed maturation by Min Yang, Yongteng Zhao, Lifang Li, Ying Qi, Penghua Gao, Jianwei Guo, Jiani Liu, Zebin Chen, Jianrong Zhao, Lei Yu

“…At different maturation stages, microbial functional genes involved in energy production and conversion as well as carbon fixation were enriched in the A. muelleri seed coats, while microbial functional genes involved in signal transduction mechanisms, amino acid transport and metabolism, carbohydrate metabolism, and lipid metabolism were more highly expressed in the seeds. …”
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Structutal-functional heart state in patients with henoch-schönlein purpura depending gallbladder condition by L. M. Strilchuk, О. М. Radchenko, S. M. Stadnik, A. L. Filipiuk, R. R. Guta

“…To reveal peculiarities of heart structure and function in patients with HSP in dependence of gall bladder condition. …”
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Fc-effector functional antibody assays for SARS-CoV-2 variants of concern by Xuemin Chen, Grace Li, Caroline Ciric, Theda Gibson, Larry J. Anderson, Larry J. Anderson, Christina A. Rostad, Christina A. Rostad

“…This study evaluated the effect COVID-19 XBB.1.5 booster vaccination on Fc-effector antibody responses to SARS-CoV-2.MethodsWe developed four assays to evaluate the Fc-effector functions of SARS-CoV-2 antibodies. ADCC and CDC assays utilized stably transfected luciferase-based target cell lines expressing SARS-CoV-2 spike variants (Ancestral, Wu-1 Omicron XBB.1.5, and EG.5) to measure antibody-mediated lysis by effector cells. …”
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Meta‐analysis of cardiac magnetic resonance in prognosticating left ventricular function in peripartum cardiomyopathy by Hawani Sasmaya Prameswari, William Kamarullah, Raymond Pranata, Iwan Cahyo Santosa Putra, Alberta Claudia Undarsa, Mohammad Iqbal, Triwedya Indra Dewi, Nuraini Yasmin Kusumawardhani, Mohammad Rizki Akbar, Astri Astuti

“…The outcome of interest was poor LV function recovery, with a follow‐up period of at least 6 months. …”
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Defect Detection: Combining Bounded Model Checking and Code Contracts by Marat Akhin, Mikhail Belyaev, Vladimir Itsykson

“…It is based on combining several recent results in BMC, namely, the use of LLVM as a baseline for model generation, employment of high-performance Z3 SMT solver to do the formula heavy-lifting, and the use of various function summaries to improve analysis efficiency and expressive power. …”
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EFFICACY AND SAFETY OF IVABRADINE AND BISOPROLOL IN PATIENTS WITH ISCHEMIC HEART DISEASE: RESULTS OF COMPARATIVE RANDOMIZED OPEN STUDY by R. D. Kurbanov, A. O. Kan, F. M. Bekmetova, A. B. Shek

“…To study influence of ivabradine as compared with bisoprolol on clinical and hemodynamic indices, exercise tolerance, endothelial function, quality of life (QL) and erectile function in patients with ischemic heart disease. …”
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Isolation and Functional Analysis of the <i>DhMYB2</i> and <i>DhbHLH1</i> Promoters from <i>Phalaenopsis</i>-Type <i>Dendrobium</i> Involved in Stress Responses and Tissue-Specific Expression by Yachen Wang, Chonghui Li, Wenjuan Zhu, Yamei Li, Xiqiang Song, Junmei Yin

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Long Non-Coding RNA TPTEP1 Exerts Tumor Suppressive Functions via Sequestering miR-4295 to Regulate Growth Arrest and DNA Damage-Inducible 45&amp;alpha; Expression in Acute Myeloid Leukemia by Liu X, Gui Y, Wang C, Xia K, Yang P

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Somatic Miwi2 modulates mitochondrial function in airway multiciliated cells and exacerbates influenza pathogenesis by Jhonatan Henao Vasquez, Jin Yuan, Chi Jing Leow, Erin Crossey, Fengzhi Shao, Senegal Carty, Viviana A. Dominguez, Ming Lo, Joseph P. Mizgerd, Jessica L. Fetterman, Nelson C. Lau, Alan Fine, Matthew R. Jones

“…We identify MIWI2 multiciliated (M2MC) cells as a rare subset of airway multiciliated cells and investigate MIWI2’s function in antiviral host defense. We analyzed transcriptomes from Miwi2 heterozygous (Miwi2+/tom) and deficient (Miwi2tom/tom) mice following influenza A infection. …”
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Słów kilka o mistrzu pokonanej rozpaczy by Roman Sabo

“…Or is it, as the author of the article suggests, a deliberate strategy to entice the reader to undertake a meticulous contemplation of Miłosz’s attitude towards the social function of poetry? Sabo suggests that Miłosz, who due to historical and social reasons, put so much stress on the utility aspect of the poetic vocation, was actually a poet who was most interested in a pure poetry unyoked from any specific cause, except the cause of relentless expression of gratitude.…”
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Exploring the relationship between APOEε4 allele and gut microbiota composition and function in healthy adults by C. Bressa, R. González-Soltero, M. Tabone, S. Clemente-Velasco, B. G. Gálvez, M. Larrosa

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The association of serum klotho with pulmonary function among US adults: a cross-sectional study by Zichong Long, Huaqiao Mu

“…Conclusions There was a comprehensive positive correlation between serum klotho and pulmonary function parameters in the adults. Further research should address to the confirmation of the causal links between klotho and pulmonary function, as well as the application of klotho to the health care and clinical treatment for pulmonary function.…”
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High glucose affects the cardiac function of diabetic Akita mice by inhibiting cardiac ATP synthase beta subunit by Yuanfang Ma, Guang Wang, Jing Li

“…Object: To explore the mechanism of diabetic cardiomyopathy that hyperglycemia may affect the cardiac function by inhibiting the expression of ATPase β subunit. …”
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Characterization of <i>SPL</i> Family Genes in Banana Reveals the Critical Role of <i>MaSPL1</i> in Regulating Fruit Ripening by Bo Wang, Tongxin Dou, Ou Sheng, Weidi He, Guiming Deng, Fangcheng Bi, Chunyu Li, Tao Dong, Qiaosong Yang, Chunhua Hu, Huijun Gao, Siwen Liu, Cancan Liu, Jihong Liu, Ganjun Yi, Yaoyao Li

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A Transcriptomic Study on the Toxic Effects of Iodide (I⁻) Wet Deposition on Pepper (<i>Capsicum annuum</i>) Leaves by Rui Yu, Zhu-Ling Ma, Min Wang, Jie Jin

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Effects of purple corn anthocyanin on slaughter performance, immune function, the caecal microbiota and the transcriptome in chickens by Xingzhou Tian, Chao Ban, Di Zhou, Hui Li, Jiaxuan Li, Xu Wang, Qi Lu

“…The findings demonstrated that dietary supplementation with PCE has the potential to improve plasma immunoglobulin, immune organ, caecal potentially beneficial bacteria levels and immune-related gene expressions, which can increase the immune function of chickens.…”
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Glucagon and alpha-cells as a novel therapeutic target in the management of diabetes mellitus by Nina Alexandrovna Petunina, Lyubov' Valentinovna Trukhina, Elena Igorevna Sinicyna, Marina Vladimirovna Shestakova

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