Advances in fluorescence imaging of RNAs in living cells based on functional nucleic acid probes by Xinyu You, Renzheng He, Si-Yang Liu, Zong Dai

“…The fluorescence functional nucleic acid probes with well-designed sequences are increasingly reported to be applied for living cell imaging, ascribing to their exceptional sensitivity and designability. …”
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Using large language models to extract plant functional traits from unstructured text by Viktor Domazetoski, Holger Kreft, Helena Bestova, Philipp Wieder, Radoslav Koynov, Alireza Zarei, Patrick Weigelt

“…Abstract Premise Functional plant ecology seeks to understand how functional traits govern species distributions, community assembly, and ecosystem functions. …”
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Identification and functional characterization of the MYB transcription factor GmMYBLJ in soybean leaf senescence by Guohua Bao, Xiao Xu, Jing Yang, Juanjuan Liu, Tianran Shi, Xiaoxuan Zhao, Xuyan Li, Shaomin Bian

“…However, our knowledge regarding the functional roles of soybean MYBs in leaf senescence is extremely limited. …”
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Deletion of CD38 enhances CD19 chimeric antigen receptor T cell function by Kimberly Veliz, Feng Shen, Olga Shestova, Maksim Shestov, Alexander Shestov, Sara Sleiman, Tyler Hansen, Roddy S. O’Connor, Saar Gill

“…In comparison with molecules such as PD1, CTLA4, LAG3, and TIM3, we found that CD38 displays more sustained and intense expression following acute activation. After deleting CD38 from human chimeric antigen receptor (CAR) T cells, we showed relative resistance to exhaustion in vitro and improved anti-tumor function in vivo. …”
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Is functional brain connectivity atypical in autism? A systematic review of EEG and MEG studies. by Christian O'Reilly, John D Lewis, Mayada Elsabbagh

“…Of note, abnormal lateralization in ASD, specifically an elevated left-over-right EEG and MEG functional connectivity ratio, has been also reported consistently across studies.…”
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Cloning and Functional Analysis of a Zeaxanthin Epoxidase Gene in <i>Ulva prolifera</i> by Hongyan He, Xiuwen Yang, Aurang Zeb, Jiasi Liu, Huiyue Gu, Jieru Yang, Wenyu Xiang, Songdong Shen

“…In order to explore the biological function of <i>ZEP</i>, a <i>ZEP</i> gene was cloned and identified from <i>U. prolifera</i>. …”
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Therapeutic reduction of neurocan in murine intracerebral hemorrhage lesions promotes oligodendrogenesis and functional recovery by Hongmin Li, Samira Ghorbani, Olayinka Oladosu, Ping Zhang, Frank Visser, Jeff Dunn, Yunyan Zhang, Chang-Chun Ling, V. Wee Yong, Mengzhou Xue

“…Difluorosamine shifted the degeneration-associated functional state of microglia/macrophages in ICH towards a regulatory phenotype. …”
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Structural and functional assessment of TBX20 gene variants in pediatric ventricular septal defect by Zhenzhen Qin, Caixia Liu, Jie Wang, Yanmei Jin

“…Structural modeling predicted that the p.Gly193Ser substitution destabilized the TBX20 protein by altering its conformation and increasing its potential energy state. Functional assays demonstrated that this variant reduced TBX20 mRNA expression and significantly attenuated transactivation of the downstream target gene ANF. …”
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Identification of the ACA/ECA gene family and preliminary verification of their functional in calcium transport in lettuce by Yuxuan Qian, Zhanhui Wu, Ning Liu, Baoju Wang, Jing Tong

“…In this study, we utilized bioinformatics methods to identify and analyze members of the ACA/ECA gene family in lettuce. The functions of certain ACA/ECA genes in lettuce were preliminary validated using TRV-VIGS. …”
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Functionalization-Dependent Cytotoxicity of Silver Nanoparticles: A Comparative Study of Chlorhexidine and Metronidazole Conjugates by Karol P. Steckiewicz, Monika Dmochowska, Elżbieta Megiel, Ewelina Barcińska, Iwona Inkielewicz-Stępniak

“…This study examines the cytotoxicity of two silver nanoparticle formulations—AgNPs conjugated with chlorhexidine (AgNPs-CHL) and AgNPs conjugated with polyethylene glycol and metronidazole (AgNPs-PEG-MET)—as examples of the surface functionalization of silver nanoparticles with drugs via sulfur–silver bonds and nitrogen–silver interactions. …”
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The impact of supplementation with highland barley in different nutrients on weight loss: The nutrients and function relationship by Fan Xie, Yuting Yan, Xin Gao, Haocheng She, Jingyi Wang, Jie Li, Yi Zhang, Jun Zhang, Zhou Zhang, Lianzhong Ai

“…Consumption of HB also ameliorated hepatic steatosis, hyperlipemia, abnormal liver function, and dysregulation of inflammatory factor expression in mice. …”
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Mapping Genetic Associations With Functional Brain Area Alterations in Schizophrenia and Implications for Cortical Development by Jun‐Ding Zhu, Chih‐Yun Chung, Shu‐Fei Lin, Shih‐Jen Tsai, Albert C. Yang, Pei‐Shan Hou

“…ABSTRACT Background While prior studies have identified regional reduction in gray matter (GM) volume in schizophrenia, it remains unclear whether these alterations are concentrated in specific brain functional areas and how they relate to genetic factors. …”
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Bioinspired surface functionalization of biodegradable mesoporous silica nanoparticles for enhanced lubrication and drug release by Xiaowei Mao, Kexin Chen, Yanlong Zhao, Chunrong Xiong, Jing Luo, Yuguang Wang, Bo Wang, Hongyu Zhang

“…Furthermore, the dual-functional nanoparticles were biocompatible and effectively reduced the expression levels of two inflammation factors such as interleukin-1β (IL-1β) and interleukin-6 (IL-6). …”
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Functional conservation and divergence of arabidopsis VENOSA4 and human SAMHD1 in DNA repair by Raquel Sarmiento-Mañús, Sara Fontcuberta-Cervera, Kensuke Kawade, Akira Oikawa, Hirokazu Tsukaya, Víctor Quesada, José Luis Micol, María Rosa Ponce

“…Here, we show that VENOSA4 (VEN4), the probable Arabidopsis thaliana ortholog of SAMHD1, also functions in DSB repair by HR. The ven4 loss-of-function mutants showed increased DNA ploidy and deregulated DNA repair genes, suggesting DNA damage accumulation. …”
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Cognitive functions and their effect on disability in learning process and knowledge application in patients with arterial hypertension by S. Ya. Yanovska

“…The aim of the investigation is to determine the influence of cognitive functions on disability in learning process and knowledge application in patients with hypertension. …”
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Effect and mechanism of PYCR1 on biological function of hepatocellular carcinoma cells under hypoxia by Jiayi Guo, Xinxin Jin, Junli Zhang, Yuming Zhang, Wenjuan Wu

“…Methods GO and KEGG enrichment analyses were used to predict the biological function and possible mechanism of PYCR1 in hypoxic microenvironments. …”
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SPECIFIC VOCABULARY IN UKRAINIAN FICTION: FUNCTIONS AND METHODS OF PRESENTATION (ON P.A. ZAHREBELNYI’S NOVELS) by Catherine S. Bondarchuk, Olha A. Chumachenko

“…Depending on the problems of the works, the author widely uses the terminology, professional and archaic vocabulary, which performs various functions in the text: a representative (nominative), communicative (informative), descriptive, emotional and expressive. …”
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PmtA functions as a ferrous iron and cobalt efflux pump in Streptococcus suis by Chengkun Zheng, Mengdie Jia, Miaomiao Gao, Tianyu Lu, Lingzhi Li, Pingping Zhou

“…Here, we established that PmtA functions as a ferrous iron [Fe(II)] and cobalt [Co(II)] efflux pump in Streptococcus suis, an emerging zoonotic pathogen responsible for severe infections in both humans and pigs. pmtA expression is induced by Fe(II), Co(II), and nickel [Ni(II)], whereas PmtA protects S. suis against Fe(II) and ferric iron [Fe(III)]-induced bactericidal effect, as well as Co(II) and zinc [Zn(II)]-induced bacteriostatic effect. …”
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Rheumatoid Arthritis and miRNAs: A Critical Review through a Functional View by Maria Cristina Moran-Moguel, Stefania Petarra-del Rio, Evangelina E. Mayorquin-Galvan, Maria G. Zavala-Cerna

“…After a critical reading, we provide in this paper a functional view with respect to miRNA biogenesis, interaction with targets that are expressed in specific cells and tissues, during different stages of inflammatory responses associated with RA, and recognized specific areas where miRNAs might also have a pathogenic role but remain undescribed. …”
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Direction-aware functional class scoring enrichment analysis of infinium DNA methylation data by Mark Ziemann, Mandhri Abeysooriya, Anusuiya Bora, Séverine Lamon, Mary Sravya Kasu, Mitchell W. Norris, Yen Ting Wong, Jeffrey M. Craig

“…Infinium Methylation BeadChip arrays remain one of the most popular platforms for epigenome-wide association studies, but tools for downstream pathway analysis have their limitations. Functional class scoring (FCS) is a group of pathway enrichment techniques that involve the ranking of genes and evaluation of their collective regulation in biological systems, but the implementations described for Infinium methylation array data do not retain direction information, which is important for mechanistic understanding of genomic regulation. …”
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