The Effect of Psychological Stress on Mucosal IL-6 and Helicobacter pylori Activity in Functional Dyspepsia by Eryati Darwin, Arina Widya Murni, Adnil E Nurdin

“…Background: pathophysiology of functional dyspepsia remains poorly understood. Many factors such as gastric motility disorder, visceral hypersensitivity, Helicobacter pylori (Hp) infection, psychological stress and excessive gastric acid secretion play roles in this symptom. …”
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Response to Training in Emotion Recognition Function for Mild TBI/PTSD Survivors: Pilot Study by J. Kay Waid-Ebbs, Kristen Lewandowski, Yi Zhang, Samantha Graham, Janis J. Daly

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The Effect of Psychological Stress on Mucosal IL-6 and Helicobacter pylori Activity in Functional Dyspepsia by Eryati Darwin, Arina Widya Murni, Adnil E Nurdin

“…Background: pathophysiology of functional dyspepsia remains poorly understood. Many factors such as gastric motility disorder, visceral hypersensitivity, Helicobacter pylori (Hp) infection, psychological stress and excessive gastric acid secretion play roles in this symptom. …”
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TMT-Opsins differentially modulate medaka brain function in a context-dependent manner. by Bruno M Fontinha, Theresa Zekoll, Mariam Al-Rawi, Miguel Gallach, Florian Reithofer, Alison J Barker, Maximilian Hofbauer, Ruth M Fischer, Arndt von Haeseler, Herwig Baier, Kristin Tessmar-Raible

“…Light receptors, encoded by functional opsin proteins, are present inside the vertebrate brain and peripheral tissues. …”
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Functional Identification and Transcriptional Activity Analysis of <i>Dryopteris fragrans HMGR</i> Gene by Meng Sun, Qian Ma, Xueqi Wang, Jialiang Guo, Jiaxuan Wang, Dongrui Zhang, Kirill Tkachenko, Wenzhong Wang, Ying Chang

“…Promoter analysis identified functional regulatory regions controlling <i>DfHMGR</i> expression, and co-expression network analysis predicted 21 potential transcriptional regulators. …”
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Beneficial Effects of Spirulina Aqueous Extract on Vasodilator Function of Arteries from Hypertensive Rats by Diva M. Villalpando, Carlos M. Verdasco-Martín, Ignacio Plaza, Juan Gómez-Rivas, Fermín R de Bethencourt, Morris Villarroel, José L. García, Cristina Otero, Mercedes Ferrer

“…The results showed that the aqueous Spirulina extract (i) increased the production of NO, did not significantly modify that of superoxide, while decreased that of hydrogen peroxide; (ii) increased the vasodilatory responses induced by ACh, NPS, and pinacidil; and (iii) increased the expression of p-Akt and HO-1. These results suggest that incubation with the aqueous Spirulina extract improves the vascular function of arteries from SHR by increasing the release/bioavailability/function of NO. …”
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Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor function. by Shelly Oommen, Mathias Francois, Maiko Kawasaki, Melanie Murrell, Katsushige Kawasaki, Thantrira Porntaveetus, Sarah Ghafoor, Neville J Young, Yoshimasa Okamatsu, John McGrath, Peter Koopman, Paul T Sharpe, Atsushi Ohazama

“…Previous studies have established that the mouse mutant ragged-opossum (Ra(op)) expresses a dominant-negative form of the SOX18 transcription factor that interferes with the function of wild type SOX18 and of the related SOXF-subgroup proteins SOX7 and -17. …”
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Involvement of CD26 in Differentiation and Functions of Th1 and Th17 Subpopulations of T Lymphocytes by Xiangli Zhao, Wenhan Wang, Kai Zhang, Jingya Yang, Hendrik Fuchs, Hua Fan

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Validation of Novel Biomarkers for Prostate Cancer Progression by the Combination of Bioinformatics, Clinical and Functional Studies. by Saeid Alinezhad, Riina-Minna Väänänen, Jesse Mattsson, Yifeng Li, Terhi Tallgrén, Natalia Tong Ochoa, Anders Bjartell, Malin Åkerfelt, Pekka Taimen, Peter J Boström, Kim Pettersson, Matthias Nees

“…However, only few predictive markers identified in silico have also been validated for clinical, functional or mechanistic relevance in disease progression. …”
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Simvastatin-Loaded Chitosan-Functionalized PLGA Nanoparticles: Characterization and Use in Intimal Hyperplasia Therapy by Ashley A. Peters, Chanpreet Kaur, Maleen Cabe, Kelly A. Langert, Kristopher Maier, Vivian Gahtan

“…Here, we tested the hypothesis that chitosan-functionalized polymeric nanoparticles (NPs) loaded with simvastatin (SL-cNPs) would (1) readily associate with endothelial cells (ECs) and vascular smooth muscle cells (VSMCs); (2) affect EC and VSMC function; and (3) reduce IH compared to systemic simvastatin. …”
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Biological function of long noncoding RNA in HER2-positive breast cancer cells by Jeeyeon Lee, Ho Yong Park, Wan Wook Kim, Soo Jung Lee, Jae-Hwan Jeong, Seung Hee Kang, Jin Hyang Jung, Yee Soo Chae

“…Although Nespas, 7SK, PSF inhibiting RNA, mascRNA, Hoxa11as, NRON, AK023948, MER11C, p53 mRNA, CAR Intergenic 10, HUC 1 and 2, ZFAS1, SCA8, and SNHG5 were also upregulated and UCA1 was downregulated, the differences were not dominent. Based on the expression result, we explored the functional role of snaR in HER2-positive breast cancer. …”
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Differential Effector Function of Tissue-Specific Natural Killer Cells against Lung Tumors by Zerick Terrell Dunbar, Salvador González-Ochoa, Thanigaivelan Kanagasabai, Alla Ivanova, Anil Shanker

“…In this study, we investigated NK cell tissue heterogeneity in relation to their phenotype and effector functions against lung tumors. Methods: Using hanging drop tumor spheroid and subcutaneously established LL/2 (LLC1) lung tumor models, we examined NK cell receptor diversity and its correlation with tissue-specific cytotoxicity through multiparametric flow cytometry, fluorescence imaging, and cytotoxicity assays. …”
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Protective effects and its mechanism of garlicin on the renal function in type 1 diabetic rats by JIANG Jing, TANG Xiao-ling, YANG Jin

“…Objective To explore the protective effects and its mechanism of garlicin on the renal function in type 1 diabetic rats. Methods After establishing the rat model of type 1 diabetes, these rats were randomly divided into normal control group（n=8）, diabetic group（n=11） and garlicin group（n=11）. …”
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FUNCTIONAL AND METABOLIC FEATURES OF BLOOD PHAGOCYTES AT DIFFERENT FORMS OF TUBERCULAR INFLAMMATORY PROCESS OF LUNGS by O. V. Berdyugina, A. V. Yershova

“…In the fibro-cavernous tuberculosis we observed leukocytosis, monocytosis, granulocytosis. The main functional feature of this clinical form is an increased amount of CD 11b+ and CD 11с+-bearing leukocytes, higher functional and metabolic activity of granulocytes, as well as expansion of CD11b+ expressing cell population and increased numbers of B-cells in peripheral blood.…”
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Chronic stress elicits sex‐specific mitochondrial respiratory functional changes in the rat heart by Caitlin P. Odendaal‐Gambrell, Cassidy O'Brien, Megan Cairns, Gerald J. Maarman, Danzil E. Joseph, Carine Smith, Fanie Rautenbach, Jeanine L. Marnewick, M. Faadiel Essop

“…In contrast, stressed males displayed increased cardiac ATP synthase levels together with diminished peroxisome proliferator‐activated receptor‐gamma coactivator‐1‐alpha (PGC‐1α) expression versus controls. These findings indicate that male mitochondria are more prone to stress‐related functional changes, while females exhibited a more protective and resilient phenotype.…”
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Effects of Gallus epidermal growth factor on immune function and intestinal development in male broilers by Yubiao Jia, Qiuming Huang, Rui Song, Jianyong Zhou, Chuansong Sun, Jianjun Lu

“…The present study aims to evaluate the effects of Gallus epidermal growth factor (gEGF) on growth performance, immune function, intestinal barrier, and the inflammatory response in broilers. …”
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Research on the function of CsMYB36 based on an effective hair root transformation system by Xi Shen, Ting Yang, Yalin Du, Ning Hao, Jiajian Cao, Tao Wu, Chunhua Wang

“…The hairy root induction system was used to efficiently investigate gene expression and function in plant root. Cucumber is a significant vegetable crop worldwide, with shallow roots, few lateral roots, and weak root systems, resulting in low nutrient absorption and utilization efficiency. …”
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Identification of Arabidopsis meiotic cyclins reveals functional diversification among plant cyclin genes. by Petra Bulankova, Svetlana Akimcheva, Nicole Fellner, Karel Riha

“…Our phenotypic and expression data provide extensive evidence that multiplication of cyclins is in plants accompanied by functional diversification.…”
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Coagulation functions and factors correlated with central nervous system infection in herpes zoster patients by Yanrong Yuan, Jing Gu, Huili Liu, Yu Wang, Zeyu Sun, Dongli Pan, Dongli Pan, Yongxing Yan

“…The coagulation parameters of the three groups were measured and compared, and the correlation between coagulation function parameters and CNS infection was analyzed by Logistic regression. the expression of coagulation factor in cerebrospinal fluid (CSF) proteomics of 28 VZVM patients and 11 HZ patients were analyzed.ResultsCompared with HCs group, plasma Fibrinogen (Fib) and D-dimer (DD) levels in HZ and VZVM group were significantly increased (P &lt;0.01), while there were no significant differences in other parameters (P &gt; 0.05). …”
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Role of USP7 in the regulation of tolerogenic dendritic cell function in type 1 diabetes by Farhan Ullah Khan, Puregmaa Khongorzul, Denis Gris, Abdelaziz Amrani

“…Conclusions Our findings underscore the role of the USP7/Ezh2 axis in maintaining tolerogenic DC functions that are required to tailor adaptive immune response and diabetes protection in NOD mice. …”
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