Expression analysis and possible functional roles of semaphorin/plexin/CRMP families in mouse pancreatic islets by Mayu Kyohara, Rie Takayanagi, Takahiro Tsuno, Esther Ong Yajima, Ryota Inoue, Naoya Yamashita, Tomoko Okuyama, Kuniyuki Nishiyama, Kohichi Matsunaga, Emi Ishida, Shuichi Ito, Yasuo Terauchi, Yoshio Goshima, Jun Shirakawa

“…Abstract Semaphorins were initially identified as axon guidance molecules that were widely expressed and involved in divergent functions in various organs, including neuronal development and immunological processes. …”
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Mapping striatal functional gradients and associated gene expression in Parkinson’s disease with continuous cognitive impairment by Xiaolu Li, Shuting Bu, Huize Pang, Hongmei Yu, Mengwan Zhao, Juzhou Wang, Yu Liu, Guoguang Fan

“…This study characterizes striatal gradient organization and its genetic underpinnings across PD cognitive trajectories. We analyzed functional connectivity gradients in 126 PD patients (spanning the cognitive spectrum from normal cognition to dementia) and 40 healthy controls, correlating spatial patterns with neurotransmitter architecture and transcriptomic profiles. …”
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Identification and validation of expression and functions of ferroptosis-related gene HILPDA in early-onset preeclampsia placentas by Qianghua Wang, Xuegu Wang, Jiaojiao Fei, Chuanyue Jiang, Yafen Tao, Nana Yang, Huijuan Chen, Chengli Dou, Biao Ding, Danli Du, Xiang Li

“…This study aimed to systematically analyze the expression and function of ferroptosis-related gene HILPDA in EOPE placentas.MethodsWe included five transcriptomic datasets (GSE148241, GSE44711, GSE74341, GSE114691, GSE10588) downloaded from the Gene Expression Omnibus (GEO) in this study. …”
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Evaluation of the Influence of <i>Tanacetum vulgare</i> Extract on Cognitive Functions and Hippocampal BDNF Expression by Borislava Lechkova, Michaela Shishmanova-Doseva, Niko Benbassat, Reneta Gevrenova, Pepa Atanassova, Nadya Penkova, Lyudmil Peychev, Petar Hrischev, Zhivko Peychev, Stanislava Ivanova

“…However, the literature data on its effects on cognitive function are scarce. The aim of the present work was to evaluate the effects of two doses of <i>T. vulgare</i> alcohol extract on cognitive functions, hippocampal brain-derived neurotrophic factor (BDNF) expression, and organ toxicity in rats. …”
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Dynamic time-varying transfer function for cancer gene expression data feature selection problem by Hao-Ming Song, Yu-Cai Wang, Jie-Sheng Wang, Yu-Wei Song, Shi Li, Yu-Liang Qi, Jia-Ning Hou

Subjects: “…Dynamic time-varying transfer function…”
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Expression and functional characterization of an anti-CD22 scFv targeting B-cell malignancies by Monireh Gholizadeh, Shahriyar Abdoli, Shafieeh Mansoori, Arash Arashkia, Farhad Riazi-Rad, Amir Ali Hamidieh, Mohammad Nouri, Zahra Sharifzadeh

“…This study aimed to optimize the expression and purification of an anti-CD22 scFv (CD22-scFv) in E. coli and evaluate its functional properties. …”
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Dynamic Expression and Functional Implications of the Cell Polarity Gene, Dchs1, During Cardiac Development by Kathryn Byerly, Cayla Wolfe, Hannah Parris, Charlotte Griggs, Emily Wilson, Matthew Huff, Molly Griggs, Jordan Morningstar, Lilong Guo, Fulei Tang, Jan Guz, Taylor Petrucci, Ranan Phookan, Brian Loizzi, Cortney Gensemer, Russell A. Norris

“…Dachsous1 (Dchs1), an atypical cadherin linked to mitral valve prolapse, is a core planar cell polarity protein whose function in the developing heart has not been fully elucidated. …”
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Circular RNA microarray expression profile and potential function of circDOCK1 in colorectal cancer by Guojing Zhang, Xiaoyan Wu, Hongmin Fu, Daqing Sun

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A Sox10 expression screen identifies an amino acid essential for Erbb3 function. by Kristina Buac, Dawn E Watkins-Chow, Stacie K Loftus, Denise M Larson, Arturo Incao, Gretchen Gibney, William J Pavan

“…These findings highlight the importance of the mutated residue for ERBB3 receptor function and activation. This study underscores the utility of using an ENU mutagenesis to identify genetic pathways regulating NC development and to dissect the roles of discrete protein domains, both of which contribute to a better understanding of gene function in a cellular and developmental setting.…”
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Gene Expression Profiles of Human Phosphotyrosine Phosphatases Consequent to Th1 Polarisation and Effector Function by Patricia Castro-Sánchez, Rocio Ramirez-Munoz, Pedro Roda-Navarro

“…Changes in gene expression levels suggest a previously nonnoted regulatory role of several PTPs in Th1 polarisation and effector function. …”
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Identification, expression profiling and potential functional roles of nuclear receptors in the social aphid Pseudoregma bambucicola by Jianjun Lu, Xiaolei Huang

“…Conclusions This study conducted bioinformatic identification of NR genes in the social aphid P. bambucicola, and investigated their potential roles in morphological differentiation and behavioral division through analysis of differential gene expression. The findings provide preliminary evidence for the functional significance of NR genes in social aphids, while offering novel insights for subsequent research exploration.…”
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RETRACTED: Palmitic Acid Impedes Extravillous Trophoblast Activity by Increasing MRP1 Expression and Function by Yunali Ashar, Qiuxu Teng, John N. D. Wurpel, Zhe-Sheng Chen, Sandra E. Reznik

“…Normal function of placental extravillous trophoblasts (EVTs), which are responsible for uteroplacental vascular remodeling, is critical for adequate delivery of oxygen and nutrients to the developing fetus and normal fetal programming. …”
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Vitamin D Antagonises the Suppressive Effect of Inflammatory Cytokines on CTLA-4 Expression and Regulatory Function. by Louisa E Jeffery, Omar S Qureshi, David Gardner, Tie Z Hou, Zoe Briggs, Blagoje Soskic, Jennifer Baker, Karim Raza, David M Sansom

“…Therefore, in this study we have examined the effects of Th17 polarising conditions on CTLA-4 expression and function in human T cells and show that Th17 conditions can suppress the expression of CTLA-4 and its transendocytic function. …”
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Profiling the expression and functional roles of mRNAs and lncRNAs associated with post-stroke aphasia by Yanling Xi, Hui Chang, Mei Qu

“…Functional enrichment analyses of these targets demonstrated the strong enrichment of co-expressed DElncRNAs and DEGs in immune system processes and the inflammatory response. …”
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Correction: Expression and Replication Studies to Identify New Candidate Genes Involved in Normal Hearing Function

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<i>SLC4A11</i> Revisited: Isoforms, Expression, Functions, and Unresolved Questions by Polina Alekseevna Kovaleva, Elena Sergeevna Kotova, Elena Ivanovna Sharova, Liubov Olegovna Skorodumova

“…Despite its clinical importance, current data on <i>SLC4A11</i> expression patterns, transcript variants, and functional roles remain inconsistent and sometimes contradictory. …”
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Drought Modulates Root–Microbe Interactions and Functional Gene Expression in Plateau Wetland Herbaceous Plants by Yuanyuan Chen, Shishi Feng, Qianmin Liu, Di Kang, Shuzhen Zou

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Sex differences in the genetics of autism spectrum disorder and their impact on gene expression associated with mitochondrial function by María de los Angeles Carcamo, Rodrigo A. Quintanilla, William Tiznado, Lina M. Ruiz

“…Using data from the Gene Expression Omnibus repository, this research explored sex-related genetic differences in ASD and their impact on mitochondrial gene expression. …”
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Mature murine supraspinatus tendons demonstrate regional differences in multiscale structure, function and gene expression. by Michael S DiStefano, Stephanie N Weiss, Courtney A Nuss, Rebecca L Betts, Biao Han, Andrew F Kuntz, Louis J Soslowsky

“…Therefore, the purpose of this study was to elucidate site-specific hierarchical structure, function, and gene expression differences in mouse supraspinatus tendons. …”
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GeneCOCOA: Detecting context-specific functions of individual genes using co-expression data. by Simonida Zehr, Sebastian Wolf, Thomas Oellerich, Matthias S Leisegang, Ralf P Brandes, Marcel H Schulz, Timothy Warwick

“…GeneCOCOA thereby provides biological insight into both gene function, and putative regulatory mechanisms by which the expression of the GOI is controlled. …”
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