Suggested Topics within your search.
Suggested Topics within your search.
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1321
Dynamic Functional Network Connectivity Analysis in Autism Spectrum Disorder: An EEG Study
Published 2024-01-01“…In this work, we aimed to elucidate the primary group distinctions in the temporal pattern of dynamic functional connectivity (dFC) estimated from task based EEG among individuals with ASD and healthy controls (HC) and explore the effect of bumetanide on brain network states. …”
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1322
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1323
UQCRC1 downregulation impairs cognitive function in mice via AMPK inactivation
Published 2025-08-01“…Additionally, pharmacological interventions aimed at activating AMPK and enhancing lysosomal function were employed to elucidate mechanistic pathways. …”
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1324
Modeling Neurological Disease by Rapid Conversion of Human Urine Cells into Functional Neurons
Published 2016-01-01“…Somatic cells can be directly converted into functional neurons by ectopic expression of defined factors and/or microRNAs. …”
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1325
Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes
Published 2013-02-01“…Studies correlating circulating and lesional classical monocytes in gene‐deficient Apoe−/− mice, adoptive transfer of gene‐deficient cells and pharmacological modulation during intravital microscopy of the carotid artery revealed a crucial function of CCR1 and CCR5 but not CCR2 or CX3CR1 in classical monocyte recruitment to atherosclerotic vessels. …”
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1326
Different functions of PHF10 isoforms – subunits of the PBAF chromatin remodeling complex
Published 2019-03-01“…Chromatin remodelling multiprotein complexes play an important role in regulation of gene expression in embryogenesis and in the adult organism. …”
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1327
The role of BMAL1 in glial cells: Implications for cognitive function in neurodegenerative diseases
Published 2025-09-01“…Disruption of the circadian rhythm may precede the typical clinical symptoms of neurodegenerative diseases and is a potential risk factor for Alzheimer’s disease (AD), associated dementias, and Parkinson’s disease (PD). The morphology and function of mammalian glial cells and their gene expression correlate with circadian rhythms. …”
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1328
MAST Kinases’ Function and Regulation: Insights from Structural Modeling and Disease Mutations
Published 2025-04-01“…We also estimate the functional consequences of disease point mutations on protein stability by integrating predictive algorithms and AlphaFold. …”
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1329
Structural and Functional Analysis of the Human IQSEC2 S1474Qfs*133 Mutation
Published 2025-04-01“…We conclude that diseases associated with the IQSEC2 S1474Qfs*133 may be due not only to the loss of function of IQSEC2 but also to the appearance of new detrimental activity. …”
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1330
Integrated Nematode Management Strategies: Optimization of Combined Nematicidal and Multi-Functional Inputs
Published 2025-03-01“…As most PPNs have a subterranean nature, the complexity of soils in the plant rhizosphere and the structures and functions of the soil food webs necessitate a grasp of the relevant biotic/abiotic factors in order to ensure their effective control. …”
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1331
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1332
Effect of Exogenous Alpha-B Crystallin on the Structures and Functions of Trabecular Meshwork Cells
Published 2018-01-01“…This study, for the first time, focused on the role of CRYAB in undesired changes of the structures and functions in trabecular meshwork (TM) cells. Methods. …”
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1333
Regulation of proliferative potential: insights into key signaling cascades and te-lomerase functions
Published 2024-10-01“…Telomerase, a ribonucleoprotein traditionally recognized for its function in telomere maintenance, is revisited in this review for its non-canonical roles. …”
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1334
Repulsive guidance molecules b (RGMb): molecular mechanism, function and role in diseases
Published 2024-01-01“…This article reviews the properties and functions of RGMb, focusing on its role under various physiological and pathological conditions.…”
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1335
CacyBP/SIP - RPL6 interaction: potential influence on ribosome function
Published 2025-07-01“…To further explore the possible role of CacyBP/SIP in ribosome function we performed several analyses using neuroblastoma NB2a cell line with stably silenced CacyBP/SIP expression. …”
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1336
Functions and Therapeutic Potentials of Long Noncoding RNA in Skeletal Muscle Atrophy and Dystrophy
Published 2025-04-01“…Finally, we explored the potential of using these lncRNAs as therapeutic targets for muscle atrophy and muscular dystrophy, including the methods of discovery and clinical application prospects for functional lncRNAs.…”
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1337
New TIPARP inhibitor rescues mitochondrial function and brain injury in ischemic stroke
Published 2024-12-01“…Knockdown of Tiparp reduces brain infarction and promotes recovery of motor function in ischemic stroke mice. A rationally designed TIPARP inhibitor, XG-04-B1, promotes repair of brain injury and recovery of motor function in ischemic stroke mice. …”
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1338
Regulation and Functions of Long Noncoding RNAs During Meloidogyne incognita Parasitism of Tomato
Published 2025-01-01“…However, at the later stage of infection, the number of M. incognita–regulated lncRNAs was dramatically reduced, with only 49 lncRNAs being identified as differentially expressed. Differentially expressed lncRNAs were predicted to encode peptides with functionally annotated domains, providing insights into the potential roles of these peptides in regulating gene expression, RNA stability and splicing, and protein-protein-interactions. …”
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1339
Surface Functionalization of ITO for Dual-Mode Hypoxia-Associated Cancer Biomarker Detection
Published 2025-03-01“…Indium tin oxide (ITO) is a transparent conducting material with exceptional electrical and optical properties, widely used in biosensing and bioelectronics. Functionalization of ITO with linker molecules enables covalent attachment of biomolecules, allowing for dual-mode optical and electrochemical detection. …”
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1340
Dietary resilience of termite gut microbiota and enzymatic function reflects feeding strategy
Published 2025-08-01“…Despite some taxon-specific responses in C. cumulans, overall microbial beta diversity remained stable in both species. Functional predictions revealed broader metabolic capacity and higher CAZyme expression in the generalist species under complex diets.DiscussionOur results suggest that microbial diversity and functional redundancy in S. euamignathus confer greater resilience to dietary perturbation, while C. cumulans displays limited plasticity consistent with dietary specialization. …”
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