miRNA mediated mitochondrial function and gene regulation associated with Alzheimer’s disease by Kumudu Subasinghe, Robert Barber, Robert Barber, Robert Barber, Nicole Phillips, Nicole Phillips

“…MicroRNAs (miRNAs) are small non-coding RNA molecules that are known to regulate gene expression in their target locations thereby contributing to epigenetic mechanisms associated with disease pathologies. …”
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Use of Self-Assembling Peptides to Enhance Stem Cell Function for Therapeutic Angiogenesis by Hyung Sub Park, Geum Hee Choi, Daehwan Kim, Tae Woo Jung, In Mok Jung, Jung Kee Chung, Taeseung Lee

“…Finally, SAPs also showed the ability to recruit endogenous host MSCs into the site of action, especially when modified to incorporate substance P as a functional motif, which when injected with exogenous MSCs, allowed for the dual presence of MSCs at the site of action. …”
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Reliable, scalable functional genetics in bloodstream-form Trypanosoma congolense in vitro and in vivo. by Georgina Awuah-Mensah, Jennifer McDonald, Pieter C Steketee, Delphine Autheman, Sarah Whipple, Simon D'Archivio, Cordelia Brandt, Simon Clare, Katherine Harcourt, Gavin J Wright, Liam J Morrison, Catarina Gadelha, Bill Wickstead

“…We describe a parental single marker line that expresses T. congolense-optimized T7 RNA polymerase and Tet repressor and show that minichromosome loci can be used as sites for stable, regulatable transgene expression with low background in non-induced cells. …”
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The multifaceted functions of SPC25 in cancer: from molecular pathways to targeted therapy by Yigang Jin, Minjie Chen, Fei Chen, Zhaofeng Gao, Xiaoping Li, Lingyu Hu, Dandan Cai, Siqi Zhao, Zhengwei Song

“…We conclude by exploring future research directions, emphasizing the need for in-depth studies to unravel the precise molecular functions of SPC25 and its therapeutic potential in cancer treatment.…”
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Functional interactions between KCNE1 C-terminus and the KCNQ1 channel. by Jerri Chen, Renjian Zheng, Yonathan F Melman, Thomas V McDonald

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Chronic marijuana usage by human pancreas donors is associated with impaired islet function. by Meirigeng Qi, John S Kaddis, Kuan-Tsen Chen, Jeffrey Rawson, Keiko Omori, Zhen Bouman Chen, Sangeeta Dhawan, Jeffrey S Isenberg, Fouad Kandeel, Bart O Roep, Ismail H Al-Abdullah

“…In conclusion, excessive marijuana use affects islet endocrine phenotype and function in vitro and in vivo. Given the increasing use of marijuana, our results underline the importance of including lifestyle when evaluating human islets for transplantation or research.…”
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Widely Targeted Metabolomics Revealed the Metabolic Basis of Physiological Function and Flavor of Natto by Xiaolong Yin, Xiaona Wang, Lili Xu, Jianzhi Zhao, Can Li, Jianqiang Lin

“…However, due to the absence of large-scale and systematic investigations into its metabolite profile, the mechanisms governing the biological functions and flavor characteristics of natto remain incompletely elucidated. …”
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Maximizing activity and selectivity of antibody-mediated effector functions using antibody mixtures by Tiexin Wang, Alec A. Desai, Greg M. Thurber, Peter M. Tessier

“…Fc-mediated effector functions are key for conferring potent antibody-mediated killing of cancer cells. …”
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Biosynthesis of modular signaling molecules requires functional diversification of carboxylesterases in Pristionchus pacificus by Pei Zhang, Penghieng Theam, Wenya Xu, Shudan Ye, Hanh Witte, Tingwei Liu, Ralf J. Sommer, Chuanfu Dong

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Emerging role and function of Hippo-YAP/TAZ signaling pathway in musculoskeletal disorders by Juanjuan Han, Jiale Zhang, Xiaoyi Zhang, Wenxin Luo, Lifei Liu, Yuqing Zhu, Qingfeng Liu, Xin-an Zhang

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Assessment of mitochondrial function and its prognostic role in sepsis: a literature review by Wagner Nedel, Nathan Ryzewski Strogulski, Afonso Kopczynski, Luis Valmor Portela

“…Given their role as a hub for various cellular functions, mitochondrial alterations induced by sepsis may hold significant pathophysiological implications and impact on clinical outcomes. …”
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Disrupted functional connectome in a rodent model of autism during social isolation by Robert Gergely Kemecsei, Robert Gergely Kemecsei, Szizel Dániel-Papp, David Barnabas Balazs, Estifanos Ghebrihiwet Tewelde, Andras Csillag, Gergely Zachar

“…Based on correlational activations we reconstructed and analyzed the functional connectome of the observed brain regions. …”
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Rhetorical function of sentence moods in Garshaspnamehpoem and the story of Bijan and Manizheh from Shahnameh by Yahya Talebian, Gholamreza Mastali Parsa, Hamid Amini Asalemi

“…The mood of the sentence expresses the poet's certainty in his words and exposes the extent of his relationship with the audience. …”
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Functional disruption of stress modulatory circuits in a model of temporal lobe epilepsy. by Aynara C Wulsin, Ana Franco-Villanueva, Christian Romancheck, Rachel L Morano, Brittany L Smith, Benjamin A Packard, Steve C Danzer, James P Herman

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Chromatin remodeling in lymphocytic function and fate: the multifaceted roles of SWI/SNF complex by Renjie Miao, Yun Liu, Yun Liu, Shuo Shen, Wenxin Wang, Wenxin Wang, Shengjun Wang, Shengjun Wang

“…Therefore, in this paper, we focus on TFs interacting with SWI/SNF complex subunits in lymphocytes, and summarize the effects of the loss of specific subunits of the SWI/SNF complex on lymphocytic differentiation and function, as well as the modification in the expression of key genes. …”
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Update on R-loops in genomic integrity: Formation, functions, and implications for human diseases by Min Zhu, Xinyu Wang, Hongchang Zhao, Zhenjie Wang

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Circular RNAs in non-alcoholic fatty liver disease: Functions and clinical significance by Qingmin Zeng, Chang-Hai Liu, Javier Ampuero, Dongbo Wu, Wei Jiang, Lingyun Zhou, Hong Li, Lang Bai, Manuel Romero-Gómez, Hong Tang

“…In this review, we briefly introduce the biogenesis, characteristics, and biological functions of circRNAs. Furthermore, we summarize circRNAs expression profiles in NAFLD by intersecting seven sequencing data sets and describe the cellular roles of circRNAs and their potential advantages as biomarkers of NAFLD. …”
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Characterization of OsCAF1 Protein Function in Rice Response to Thermal Stress by Vu-Bao Nguyen, Chung-An Lu

“…However, the specific function of OsCAF1 proteins under heat stress in rice remains poorly understood. …”
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Bile acids affect intestinal barrier function through FXR and TGR5 by Guangyao Song, Yuxiao Xie, Yuxiao Xie, Lanlan Yi, Wenjie Cheng, Huijin Jia, Wenzhe Shi, Qiwei Liu, Ligui Fang, Shiqi Xue, Dan Liu, Junhong Zhu, Sumei Zhao

“…Due to the abundant expression of bile acid receptors and the importance of the intestine in preventing pathogen invasion, researchers are increasingly focused on the function of bile acids in this system. …”
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Identification of novel TCOF1 mutations in Treacher Collins syndrome and their functional characterization by Ying Chen, Run Yang, Xin Chen, Tianyu Zhang, Chenlong Li, Jing Ma

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