PGC-1α activation to enhance macrophage immune function in mycobacterial infections. by Joel R Frandsen, Zhihong Yuan, Brahmchetna Bedi, Zohra Prasla, Seoung-Ryoung Choi, Prabagaran Narayanasamy, Ruxana T Sadikot

“…Importantly, rescuing expression of PGC-1α and TFAM using pharmacologic approaches restored macrophage immune function. …”
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Plasticity of GABAA Receptors during Pregnancy and Postpartum Period: From Gene to Function by Valentina Licheri, Giuseppe Talani, Ashish A. Gorule, Maria Cristina Mostallino, Giovanni Biggio, Enrico Sanna

“…These data suggest that alterations in GABAA receptor expression and function may be related to neurological and psychiatric disorders associated with crucial periods in women. …”
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A convenient research strategy for functional verification of epigenetic regulators during spermatogenesis by Shan Li, Ying Yuan, Ke-Yu Zhang, Yi-Dan Guo, Lu-Tong Wang, Xiao-Yuan Zhang, Shu Zhang, Qi Yan, Rong Zhang, Jie Chen, Feng-Tang Yang, Jing-Rui Li

“…As Jumonji domain-containing protein 1A (JMJD1A) and Jumonji domain-containing protein 2C (JMJD2C) demethylases catalyze histone H3 lysine 9 dimethylation (H3K9me2), we firstly analyzed the expression profile of the two demethylases and then investigated their function. …”
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Spatiotemporal and functional characterisation of the Plasmodium falciparum cGMP-dependent protein kinase. by Christine S Hopp, Christian Flueck, Lev Solyakov, Andrew Tobin, David A Baker

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The complete non-perturbative partition function of minimal superstring theory and JT supergravity by Dan Stefan Eniceicu, Chitraang Murdia, Andrii Torchylo

“…Abstract We derive an exact convergent expression for the partition function of the N $$ \mathcal{N} $$ = 1 (2, 4k) minimal superstring theory with type 0B GSO projection in the ungapped phase by leveraging the duality between this theory and a double-scaled unitary matrix integral. …”
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Transcriptomic analysis reveals the function of m6A regulators in aged cochlea by Yanbing Lai, Bo Su, Xiaodi Wang, Chenghui Zeng, Hanqi Chu, Liangqiang Zhou, Dan Bing

“…N6-methyladenosine (m6A) modification in regulating gene expression and cellular functions has been implicated in the development of various diseases. …”
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Identification and Functional Analysis of PANoptosis‐Associated Genes in the Progression From Sepsis to ARDS by Zhong‐Hua Lu, Yan Tang, Hu Chen, Feng Liu, Mei Liu, Lu Fu, Xian‐Kai Wang, Ming‐Juan Li, Wei‐Li Yu, Yun Sun

“…NDRG1 showed a positive correlation with activated dendritic cells, whereas DDX3X, PTPRC, and TNFSF8 were positively associated with neutrophils and negatively correlated with CD56bright NK cells. Functional enrichment analysis highlighted spliceosome function, MAPK signaling, endocytosis, and antigen processing pathways as significantly associated with these PRGs. …”
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Functional Properties and Promotion Effect on Osteoblastogenic Differentiation of Tuna Bone Collagen Peptides by Guanmiao XIAN, Yijing CAI, Wenhua MIAO, Yufang ZHOU, Shiqi HU, Conghan SHU, Bin ZHENG

“…The study was to investigate the functional properties of tuna bone collagen peptides (TBCP) and their effects on the proliferation, differentiation and mineralization of MC3T3-E1 osteoblasts. …”
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Function and mechanism of cancer-testis antigen CT63 in chronic myeloid leukemia by KONG Ruxin, ZHOU Yaqun, WEI Tingyi, LEI Ming

“…Phorbol 12-myristate 13-acetate (PMA)-induced monocyte/macrophage differentiation experiment was carried out to investigate the role of CT63 in the differentiation of K562 cells in vitro. Mitochondrial function was assessed to determine the impact of CT63 on CML cells both in vivo and in vitro.Results·The Kaplan-Meier survival curve indicated that low expression levels of CT63 were correlated with longer survival in patients with myeloid leukemia. …”
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Assessment of NUDT5 in Endometrial Carcinoma: Functional Insights, Prognostic and Therapeutic Implications by Hongfei Yu, Lingling Zu, Yuqin Zang, Fei Teng, Tao Wang, Ming Wu, Yingmei Wang, Fengxia Xue

“…<b>Methods</b>: This study analyzed gene expression data from The Cancer Genome Atlas and performed tissue microarray validation to assess <i>NUDT5</i> expression in EC samples. …”
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Toxicity and biodistribution comparison of functionalized nanodiamonds, quantum dot nanocarbons and gold nanoparticles by Elena Alexander, Kam W. Leong

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Transcriptomic analysis of bone transport reveals different functions between both ends by Maochun Wang, Jiao Zhang, Chongxu Qiao, Shunchao Yan, Weicheng Gao, Guoping Wu

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FUNCTIONAL PROPERTIES OF IFNΑ-INDUCED DENDRITIC CELLS IN THE PATIENTS WITH PULMONARY TUBERCULOSIS by L. V. Sakhno, O. Yu. Leplina, Zh. M. Raspay, M. A. Tikhonova, E. V. Kurganova, I. P. Gileva, S. D. Nikonov, O. A. Zhdanov, A. A. Ostanin, E. R. Chernykh

“…Abstract. Some functional properties of IFNα-induced dendritic cells (DCs) from the patients with pulmonary tuberculosis (PT) were under study. …”
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Biological Function of MicroRNA193a-3p in Health and Disease by Ilaria Grossi, Alessandro Salvi, Edoardo Abeni, Eleonora Marchina, Giuseppina De Petro

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REDD1 functions at the crossroads between the therapeutic and adverse effects of topical glucocorticoids by Gleb Baida, Pankaj Bhalla, Kirill Kirsanov, Ekaterina Lesovaya, Marianna Yakubovskaya, Kit Yuen, Shuchi Guo, Robert M Lavker, Ben Readhead, Joel T Dudley, Irina Budunova

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Functional Study of Opsin Genes in <i>Pardosa astrigera</i> (Araneae: Lycosidae) by Shuxin Zhai, Boqi Ren, Xinghua Zhang, Fangyu Shen, Min Ma, Xinmin Li, Rui Li

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EDUCATIONAL INTENTION IN ADVERTISING AND BUSINESS PR TEXTS: FUNCTIONAL LOAD AND GENRE REALIZATION by A. A. Goryachev

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Effects of aminooxyacetic acid on learning and memory function and neurochemical changes in chronic alcoholism by Hongbo Jiang, Xunling Wang, Yingwei Liang, Yinghan Hou, Xinping Yue, Zhiyi Zhang, Dan Chen, Xinyi Fan, Ailin Du

“…Objective: This study aimed to investigate the effect of aminooxyacetic acid (AOAA) on cognitive function, particularly learning and memory, in a rat model of chronic alcoholism. …”
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The function and significance of SELENBP1 downregulation in human bronchial epithelial carcinogenic process. by Gu-Qing Zeng, Hong Yi, Peng-Fei Zhang, Xin-Hui Li, Rong Hu, Mao-Yu Li, Cui Li, Jia-Quan Qu, Xingming Deng, Zhi-Qiang Xiao

“…However, there is little information on expression and function of SELENBP1 during human lung squamous cell cancer (LSCC) carcinogenesis.…”
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MLKL deficiency elevates testosterone production in male mice independently of necroptotic functions by Shene Chiou, Wayne Cawthorne, Thomas Soerianto, Vinzenz Hofferek, Komal M. Patel, Sarah E. Garnish, Emma C. Tovey Crutchfield, Cathrine Hall, Joanne M. Hildebrand, Malcolm J. McConville, Kate E. Lawlor, Edwin D. Hawkins, Andre L. Samson, James M. Murphy

“…Thus, MLKL serves two roles in the mouse testes – one involving the canonical response of macrophages to necroptotic insult, and the other a non-canonical function in male reproductive hormone control.…”
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