Regulation of PPARγ Coactivator-1α Function and Expression in Muscle: Effect of Exercise by Giulia Uguccioni, Donna D'souza, David A. Hood

“…Posttranslational modifications also regulate the function of PGC-1α, with a multitude of upstream molecules targeting the protein to modify its activity and/or expression. …”
Get full text

Genome-wide analysis of long non-coding RNA expression and function in colorectal cancer by Fangyuan Jing, Huicheng Jin, Yingying Mao, Yingjun Li, Ye Ding, Chunhong Fan, Kun Chen

“…Long non-coding RNAs (lncRNAs) are widely transcribed in the genome, but their expression profile and roles in colorectal cancer are not well understood. …”
Get full text

The Effect of Radixin on the Function and Expression of Organic Anion Transporting Polypeptide 1B1 by Chunxu Ni, Longxia Tang, Xuyang Wang, Zichong Li, Mei Hong

“…Oligomerization with regulatory proteins is a common mechanism for regulating membrane protein functions. In the present study, we found that knocking down the scaffold protein radixin, which is the major member of the ERM family expressed in the liver, significantly enhanced the uptake function of OATP1B1. …”
Get full text

PAH-pollution effects on sensitive and resistant embryos: Integrating structure and function with gene expression. by Goran Bozinovic, Damian Shea, Zuying Feng, David Hinton, Tim Sit, Marjorie F Oleksiak

Get full text

Recombinant expression and functional analysis of transgelin-like protein from the shell of Mytilus coruscus by JIANG Yuting, SUN Qi, XU Huanzhi, SHEN Wang, ZHANG Xiaolin, FAN Meihua, LIAO Zhi

“…Transgelin-like protein (TLP) is a novel shell matrix protein identified previously from the myostracum layer of Mytilus coruscus shell. For exploring its function in the shell formation of mussel, the TLP was recombinantly expressed by Escherichia coli expression system based on the sequence analysis and codon optimization. …”
Get full text

Association of TLR4 expression and genomic instability with renal function markers in diabetic nephropathy by Ayat Rasheed Hameed, Rasha Salih Nuhair

Subjects: “…genetic biomarkers renal function…”
Get full text

Expression level of nuclear steroid hormone receptors in endometrium influence on female reproductive function by N. V. Avramenko, O. V. Kabachenko, V. G. Maxymenko, D. Ye. Barkovsky

“…Recent studies have shown that the functional state of the endometrium is determined by the number of endometrial tissue receptors to corresponding steroid hormones. …”
Get full text

Dual-Function Vector for Protein Expression in Both Mammalian Cells and Xenopus laevis Oocytes by T. Jespersen, M. Grunnet, K. Angelo, D.A. Klærke, S.-P. Olesen

“…To address this problem, we have constructed a plasmid vector, pXOOM, that can function as a template for expression in both oocytes and mammalian cells. …”
Get full text

Effect of transverse aortic constriction on cardiac structure, function and gene expression in pregnant rats. by Nils Thomas Songstad, David Johansen, Ole-Jacob How, Per Ivar Kaaresen, Kirsti Ytrehus, Ganesh Acharya

“…Some differences in cardiac structure, function and gene expression between pregnant and non-pregnant rats following TAC indicated that afterload increase is less tolerated in pregnancy.…”
Get full text

Recombinant Expression and Functional Analysis of the AEJ-CHAP Domain from Staphylococcus aureus Endolysin by Jingjing DENG, Hui YIN, Waner LI, Zhanpeng LI, Jian LI, Hongzhou LÜ

Get full text

Loss of Hoxa5 function affects Hox gene expression in different biological contexts by Béatrice Frenette, Josselin Guéno, Nicolas Houde, Kim Landry-Truchon, Anthony Giguère, Theyjasvi Ashok, Abigail Ryckman, Brian R. Morton, Jennifer H. Mansfield, Lucie Jeannotte

“…We applied bulk RNA-seq assays to characterize the transcriptional impact of the loss of Hoxa5 gene function in seven different biological contexts, including developing respiratory and musculoskeletal tissues that present phenotypes in Hoxa5 mouse mutants. …”
Get full text

Determining Aspergillus fumigatus transcription factor expression and function during invasion of the mammalian lung. by Hong Liu, Wenjie Xu, Vincent M Bruno, Quynh T Phan, Norma V Solis, Carol A Woolford, Rachel L Ehrlich, Amol C Shetty, Carrie McCraken, Jianfeng Lin, Michael J Bromley, Aaron P Mitchell, Scott G Filler

Get full text

Neutrophil granulocyte functional status and expression of apoptosis markers in children with type 1 diabetes by Lyudmila Yur'evna Barycheva, Natalya Eduardovna Erdni-Goryaeva, Galina Alekseevna Alexandrovich

“…A reduction in the bactericidal activity of NGs with deficiencies in phagocytosis, secretion of active oxygen radicals and functional reserve was found. An increase in the apoptotic potential of NGs was demonstrated, which was accompanied by an increase in CD95 expression and a decrease in BCL2 expression. …”
Get full text

Functional thalamocortical innervation of VIP- and SST-expressing GABAergic interneurons in mouse barrel cortex by Michael Feyerabend, Mirko Witte, Martin Möck, Jochen F. Staiger

Get full text

Expression and analysis of partial functional domains of H11 gene from Haemonchus contortus by ZHANG Hong-li, JIANG Xiao-lei, ZHOU Qian-jin, DU Ai-fang

“…Partial fragment of H11 gene containing several functional domains from Haemonchus contortus was cloned and expressed after bioinformatics analysis of H11 with the soft ware. …”
Get full text

The role of the tricellular junction protein ILDR2 in glomerulopathies: Expression patterns and functional insights by Florian Siegerist, Felix Kliewe, Elke Hammer, Paul Schakau, Joanne Ern Chi Soh, Claudia Weber, Maja Lindenmeyer, Simone Reichelt-Wurm, Vedran Drenic, Christos Chatziantoniou, Christos E. Chadjichristos, Yiying Zhang, Stefan Simm, Miriam C. Banas, Matthias Nauck, Uwe Völker, Nicole Endlich

Get full text

Expression characteristics and functional identification of PpD2 gene in peach (Prunus persica) by XIE Hefang, ZHANG Yajia, ZHANG Junjie, LIAN Xiaodong, ZHANG Haipeng, CHENG Jun, WANG Wei, HOU Nan, WANG Lei, ZHENG Xianbo, FENG Jiancan, WANG Xiaobei, TAN Bin

Get full text

Expression and replication studies to identify new candidate genes involved in normal hearing function. by Giorgia Girotto, Dragana Vuckovic, Annalisa Buniello, Beatriz Lorente-Cánovas, Morag Lewis, Paolo Gasparini, Karen P Steel

“…Considerable progress has been made in identifying deafness genes, but still little is known about the genetic basis of normal variation in hearing function. We recently carried out a Genome Wide Association Study (GWAS) of quantitative hearing traits in southern European populations and found several SNPs with suggestive but none with significant association. …”
Get full text

Computational analysis of the functional impact of MHC-II-expressing triple-negative breast cancer by Yang Cui, Weihang Zhang, Xin Zeng, Yitao Yang, Sung-Joon Park, Kenta Nakai, Kenta Nakai

“…We implicated that this subpopulation is preferentially present in proximity to regions in immune infiltration of TNBC patient cohorts with a better prognosis, suggesting the functional importance of MHC-II-expressing tumor cells in modulating the immune landscape and influencing patient survival outcomes. …”
Get full text

Analysis of selenocysteine insertion sequence element, structures and functions and expression profiles of selenoprotein T in chicken by Ge Yansong, Cao Changyu, Wang Lili, Li Nan, Jiang Xiuqing, Li Jinlong

Subjects: Get full text