Specific functions of BIG1 and BIG2 in endomembrane organization. by Frédéric Boal, David J Stephens

“…In contrast, suppression of BIG1 induces the formation of Golgi mini-stacks still polarized and functional in terms of cargo export.<h4>Conclusions</h4>A key finding from our work is that suppression of BIG1 expression results in a fragmentation of the Golgi apparatus. …”
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Identification of Key Functional Modules and Immunomodulatory Regulators of Hepatocellular Carcinoma by Ding Luo, Xiang Zhang, Xiao-Kai Li, Gang Chen

“…We identified 687 differentially expressed mRNAs and 260 differentially expressed lncRNAs. …”
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HNP-1: From Structure to Application Thanks to Multifaceted Functions by Jiaqi Zhang, Zhaoke Liu, Zhihao Zhou, Zile Huang, Yifan Yang, Junzhu Wu, Yanhong Liu

“…This review explores the structure and function of HNP-1, discussing its gene expression, distribution, immune functions and the regulatory elements controlling its production, alongside insights into its antimicrobial mechanisms and potential clinical applications as an antimicrobial agent. …”
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Lysine crotonylation in disease: mechanisms, biological functions and therapeutic targets by Yu Ji, Shanshan Liu, Yiqiao Zhang, Yiyang Min, Luyang Wei, Chengjian Guan, Huajing Yu, Zhongtao Zhang

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Aberrant Peripheral Immune Function in a Good Syndrome Patient by Xian Chen, Jie-xin Zhang, Wen-wen Shang, Wei-ping Xie, Shu-xian Jin, Fang Wang

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Psycholinguistic Study of Functioning of Cognitions and Metacognitions on the Levels of Social Intelligence by Eduard Ivashkevych, Alla Yatsjuryk

“…The main function of social intelligence is to predict the behavior of others. …”
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Lactylation in CNS disorders: mechanisms, cellular function, and disease relevance by Jiaxin Tian, Tongyu Zhang, Ruidan Zhang, Sijia Hao, Jingyu Dong, Yiyan Chen, Jinpeng Zhou, Yang Tian

“…This process precisely regulates protein function and gene expression, profoundly influencing the progression of various diseases. …”
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Epigenetic Properties of Compounds Contained in Functional Foods Against Cancer by Giulia Casari, Brenda Romaldi, Andrea Scirè, Cristina Minnelli, Daniela Marzioni, Gianna Ferretti, Tatiana Armeni

“…These changes play a critical role in modulating cell function in both healthy and pathological conditions. …”
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Correlation of peripheral olfactomedin 1 with Alzheimer’s disease and cognitive functions by Chunxiao Wei, Guimei Zhang, Xiaoshu Fu, Meng Zhao, Weijie Zhai, Yanxin Shen, Li Sun

“…Abstract Olfactomedin 1 (OLFM1) is thought to be involved in neuronal development, synaptic structure and function. However, the expression level of peripheral OLFM1 in Alzheimer’s disease (AD) and its role in AD are unclear. …”
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Protective Function of STAT3 in CVB3-Induced Myocarditis by Diana Lindner, Moritz Hilbrandt, Katharina Marggraf, P. Moritz Becher, Denise Hilfiker-Kleiner, Karin Klingel, Matthias Pauschinger, Heinz-Peter Schultheiss, Carsten Tschöpe, Dirk Westermann

“…A complete virus clearance and an attenuated inflammation were examined in both groups WT and STAT3 KO mice 4 weeks after infection, but the cardiac function in STAT3 KO mice was significantly decreased in contrast to the infected WT mice. …”
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CERTAINTY/UNCERTAINTY AS GRAMMATICAL AND AS A HIDDEN FUNCTIONAL-SEMANTIC CATEGORY by Hanna M. Udovichenko

“…The study of the category of definiteness/indefiniteness (CDI) both in the morphological and functional-semantic aspect, brings about a wide range of theoretical problems associated with the reference, semantics of articles in article languages, types of matching articles of the same name in different article languages (for example, what semantic differences between the definite article in French and English are), as well as the types of correspondence between the manifestations of a hidden category of definiteness/indefiniteness in article languages and its grammatical expression CDI (determination) in article languages. …”
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Functional Overload Enhances Satellite Cell Properties in Skeletal Muscle by Shin Fujimaki, Masanao Machida, Tamami Wakabayashi, Makoto Asashima, Tohru Takemasa, Tomoko Kuwabara

“…Our analysis showed that functional overload induces the expression of MyoD in satellite cells and enhances the proliferative capacity and differentiation potential of these cells. …”
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Physical function evaluation in volleyball training based on intelligent GRNN by Kaiyuan Dong, Borhannudin bin Abdullah, Hazizi bin Abu Saad, Chenxi Lu

“…Three heterogeneous kernel functions, namely Gaussian kernel, radial basis kernel, and Matern kernel, are introduced, and a local weighted response mechanism is constructed to enhance the expression ability of nonlinear physiological signals. …”
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Functional Characterization of Olfactory Proteins Involved in Chemoreception of Galeruca daurica by Ling Li, Wen-Bing Zhang, Yan-Min Shan, Zhuo-Ran Zhang, Bao-Ping Pang

“…In order to further explore the olfactory functions of GdauOBP15 and GdauCSP5, RNA interference (RNAi) and electroantennogram (EAG) experiments were conducted. …”
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Structures and functions of the MICOS: Pathogenesis and therapeutic implications in Alzheimer's disease by Zihan Wang, Kaige Zhang, Minghao Huang, Dehao Shang, Xiaomin He, Zhou Wu, Xu Yan, Xinwen Zhang

“…In the present review, we introduce current understanding of MICOS structures and functions, highlight MICOS pathogenesis in AD, and summarize the available MICOS-targeting drugs potentially useful for AD.…”
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Identification of functional non-coding variants associated with orofacial cleft by Priyanka Kumari, Ryan Z. Friedman, Sarah W. Curtis, Lira Pi, Kitt Paraiso, Axel Visel, Lindsey Rhea, Martine Dunnwald, Anjali P. Patni, Daniel Mar, Karol Bomsztyk, Julie Mathieu, Hannele Ruohola-Baker, Elizabeth J. Leslie-Clarkson, Michael A. White, Barak A. Cohen, Robert A. Cornell

“…Genome wide association studies (GWAS) of isolated OFC have identified common single nucleotide polymorphisms (SNPs) in many genomic loci where the presumed effector gene (for example, IRF6 in the 1q32 locus) is expressed in embryonic oral epithelium. To identify candidates for functional SNPs at eight such loci we conduct a massively parallel reporter assay in a fetal oral epithelial cell line, revealing SNPs with allele-specific effects on enhancer activity. …”
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Food Toxicology and Safety: Evaluating Dietary Risks and Functional Ingredients by Sujaritha Jayaraj, Lavanya Kothandan, Vijay Babu Murugan, Saravana Kumar Prakash, Vandhana Vijayakumar, Elizabeth Rani

“…Future directions should emphasize the development of functional foods enriched with bioactive phytochemicals, the implementation of technological interventions to improve traceability and contamination control, and the strengthening of global regulatory frameworks—including pesticide regulation and food labeling policies. …”
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Genomic and functional analysis of rmp locus variants in Klebsiella pneumoniae by Margaret M. C. Lam, Stephen M. Salisbury, Logan P. Treat, Ryan R. Wick, Louise M. Judd, Kelly L. Wyres, Sylvain Brisse, Kimberly A. Walker, Virginia L. Miller, Kathryn E. Holt

“…Additionally, we examine the functionality of representatives for variants of rmpADC introduced into a mutant strain lacking its native rmpADC locus. …”
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Investigation of Phagocyte Functions in Pseudomonas-Colonized Cystic Fibrosis Patients by Handan Duman Şenol, Meral Barlık, Ezgi Topyıldız, Figen Gülen, Güzide Aksu, Necil Kütükçüler, Esen Demir, Neslihan Edeer Karaca

“…Conclusion: Our results from a small group of patients does not support impaired functions such as migration and phagocytosis of neutrophils in patients with CF. …”
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Maternal chitosan oligosaccharide supplementation during late gestation and lactation optimizes placental function in sows and intestinal function in 21-day-old IUGR suckling pigle... by Xintao Wang, Xintao Wang, Tingting Fang, Tingting Fang, Daiwen Chen, Daiwen Chen, Junning Pu, Junning Pu, Gang Tian, Gang Tian, Jun He, Jun He, Ping Zheng, Ping Zheng, Xiangbing Mao, Xiangbing Mao, Aimin Wu, Aimin Wu, Bing Yu, Bing Yu

“…The present study investigated the effect of COS as a dietary supplement for sows during late gestation and lactation on their productivity, placental function, and the intestinal health of IUGR piglets. …”
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