Succinate Regulates Endothelial Mitochondrial Function and Barrier Integrity by Reham Atallah, Juergen Gindlhuber, Wolfgang Platzer, Rishi Rajesh, Akos Heinemann

“…Nevertheless, how endothelial cell function and phenotype are altered by elevated intracellular succinate has not been addressed yet. …”
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Identification of a Novel Antibacterial Function of Mammalian Calreticulin by Yichao Ma, Jiachen Liu, Xinming Qin, Xiaojing Cui, Qian Yang

“…Calreticulin is a highly conserved and multifunctional molecular chaperone ubiquitously expressed in humans and animals. Beyond its well-established roles in calcium homeostasis, protein folding, and immune regulation, recent studies in aquatic species have suggested a previously unrecognized antimicrobial function of calreticulin. …”
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The Importance of Beloved’s Magical Feminism in Understanding the Function of Memorials by Yassmine BOUKHALKHAL & Djamel Eddine BELABDLI

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Characterization and functional analysis of chicken promyelocytic leukemia protein by Shengnan Wang, Jingwen Li, Tiantian Miao, Tuofan Li, Zhimin Wan, Quan Xie, Hongxia Shao, Aijian Qin, Jianqiang Ye

“…In this study, chPML gene was cloned, and its several functions were characterized. We found that chPML was widely expressed in different tissues of chickens, and showed different subcellular distribution pattern in DF-1 cells comparing with LMH and HD11 cells. …”
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The functions of Metaphor in the Religious Aspects of Al -Sayyab's Poetry by Ebtesam Hamdan, Hind Akrama

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Functional omics of ORP7 in primary endothelial cells by Juuso H. Taskinen, Minna Holopainen, Hanna Ruhanen, Miesje van der Stoel, Reijo Käkelä, Elina Ikonen, Salla Keskitalo, Markku Varjosalo, Vesa M. Olkkonen

“…To conclude, the present study suggests multifaceted functions of ORP7 in lipid homeostasis, angiogenic tube formation, and gene expression of lipid metabolism, inflammation, and cell cycle in primary endothelial cells.…”
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Enzyme-independent functions of HDAC3 in the adult heart by Sichong Qian, Chen Zhang, Wenbo Li, Shiyang Song, Guanqiao Lin, Zixiu Cheng, Wenjun Zhou, Huiqi Yin, Yueli Wang, Haiyang Li, Ying H. Shen, Zheng Sun

“…Tethering LAP2β to the HDAC3 Δ33–70 mutant restored its ability to rescue gene expression. Finally, HDAC3 depletion, not loss of HDAC3 enzymatic activity, exacerbates cardiac contractile functions upon aortic constriction. …”
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The Role of VN In Functional Syntax: Some OE Patterns by Javier Martín Arista

“… In this paper we restrict, in favour of X constituents, the role played by VN in a functional syntax. More specifically, we suggest that the element central to the formulation of synchronic and diachronic expression rules is the focusbearing constituent, that is, X-not VN-in languages that show full or partial OV morphosyntax. …”
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Maturation of small nucleolar RNAs: from production to function by Sarah F. Webster, Homa Ghalei

“…Besides their classic roles in ribosome biogenesis, snoRNAs are also implicated in several other cellular activities including regulation of splicing, transcription, RNA editing, cellular trafficking, and miRNA-like functions. Mature snoRNAs must undergo a series of processing steps tightly regulated by transiently associating factors and coordinated with other cellular processes including transcription and splicing. …”
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Functionalized hydrogel-based colorimetric sensor for Cu2+ detection by Minh-Kha Nguyen, Chau-Nha-Trang Nguyen, Khanh-Binh Vo

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Twist-2 controls myeloid lineage development and function. by Andrew B Sharabi, Melissa Aldrich, Drazen Sosic, Eric N Olson, Alan D Friedman, Sung-Hyung Lee, Si-Yi Chen

“…Thus, this study reveals the critical role of Twist-2 in regulating the development of myeloid lineages, as well as the function and inflammatory responses of mature myeloid cells.…”
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β-Glucan Subverts the Function of Myeloid Cells in Neonates by Yingying Chen, Hui Li, Lin Zhu, Quan Yang, Jie Zhou

“…Here, we found that β-glucan did not affect the frequencies and numbers of myeloid cells in the spleen and bone marrow from neonates. Functional assay revealed that β-glucan from neonates compromised the immunosuppressive function of immature myeloid cells, which were myeloid-derived suppressor cells (MDSCs). …”
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Unveiling the multifaceted functions of TRIM proteins in glioma pathogenesis by Wenjie Wu, Youxi Xie, Cheng Jiang, Xiaobing Jiang

“…This review comprehensively explores the diverse functions of TRIM proteins in gliomas, including their expression patterns, prognostic significance, and mechanisms of action that are both ubiquitination-dependent and -independent. …”
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Behavioral and intellectual functioning in patients with tyrosinemia type I by Agnieszka Kowalik, Katarzyna Kuśmierska, Marcin Biernacki, Anna Jakubowska-Winecka, Marta Biernacka, Monika Pohorecka, Jolanta Sykut-Cegielska

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Lactylation modification in cancer: mechanisms, functions, and therapeutic strategies by Mengqi Lv, Yefei Huang, Yansu Chen, Kun Ding

“…Current research focuses on the mechanisms and functions of histone lactylation in cancer, including its role in gene expression regulation, signal transduction, and protein synthesis. …”
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Functions and applications of RNA interference and small regulatory RNAs by Feng Xuezhu, Guang Shouhong

“…Since its discovery, RNAi has been widely applied in functional genomic studies and a range of practical applications. …”
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Molecular Mechanisms and Function Prediction of Long Noncoding RNA by Handong Ma, Yun Hao, Xinran Dong, Qingtian Gong, Jingqi Chen, Jifeng Zhang, Weidong Tian

“…Recently, whole genome transcriptomic analyses have identified large numbers of dynamically expressed long noncoding RNAs (lncRNAs), many of which are involved in a variety of biological functions. …”
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Distribution and functional significance of KLF15 in mouse cerebellum by Dan Li, Shuijing Cao, Yanrong Chen, Yueyan Liu, Kugeng Huo, Zhuangqi Shi, Shuxin Han, Liecheng Wang

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Restoration of Endothelial Function in Pparα−/− Mice by Tempol by Neerupma Silswal, Nikhil Parelkar, Jon Andresen, Michael J. Wacker

“…There was no difference in relaxation between WT and Pparα−/− aorta to treatment with a nitric oxide (NO) surrogate indicating impairment in endothelial function. Endothelial NO levels as well as NO synthase expression were reduced in Pparα−/− aortas, while superoxide levels were elevated. …”
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Oxidative Stress, Apoptosis, and Mitochondrial Function in Diabetic Nephropathy by Sonia Sifuentes-Franco, Diego Enrique Padilla-Tejeda, Sandra Carrillo-Ibarra, Alejandra Guillermina Miranda-Díaz

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