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Proteins Involved in the Trafficking and Functional Synaptic Expression of AMPA and KA Receptors
Published 2002-01-01“…The molecular and cellular mechanisms that regulate the synaptic localisation and functional expression of AMPARs and KARs are objects of concerted research. …”
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Integrated functional, gene expression and genomic analysis for the identification of cancer targets.
Published 2009-01-01“…This approach was verified by the identification of PIK3CA, silencing of which was selectively lethal to the MCF7 cell line, which harbours an activating oncogenic PIK3CA mutation. We combined our functional RNAi approach with gene expression and genomic analysis, allowing the identification of several novel kinases, including WEE1, that are essential for viability only in cell lines that have an elevated level of expression of this kinase. …”
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43
On Computational Constructions in Function Spaces
Published 2023-04-01“…W_1^{l}[a; b],$ and $f^{(l)}$ is $(k,L)$-differentiable at the point $x_0,$ then $f$ is approximated by a Taylor polynomial up to $ o\big((x{-}x_0)^{l+k}\big),$ and the expansion coefficients can be found in the above way. To study functions from $L_1$ on a set, a discrete "global" construction of a difference expression is used: based on the quotient ${\bf\Delta}_h^m(f, \cdot)$ and $h^m$ the sequence is built $\big{{\bf\Lambda}_n^m[f]\big}$ of piecewise constant functions subordinate to partitions half-interval $[a; b)$ into $n$ equal parts. …”
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Express Polymer Letters is renewing
Published 2022-01-01“…Express Polymer Letters has been published by the Department of Polymer Engineering at the Budapest University of Technology and Economics (BME) for 15 years. …”
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Chromatin accessibility and transcriptomic profiles of sheep pituitary function associated with fecundity
Published 2025-05-01“…Chromatin accessibility enables physical interactions between promoters and chromatin-binding factors to drive the gene expression. Despite this mechanistic insight, the chromatin accessibility landscape of the sheep pituitary and its functional implications for reproductive traits remain largely unexplored. …”
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Defining the transcriptome and proteome in three functionally different human cell lines
Published 2010-12-01“…Abstract An essential question in human biology is how cells and tissues differ in gene and protein expression and how these differences delineate specific biological function. …”
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Molecular Mechanisms of Endometrial Functioning in Women with Polycystic Ovary Syndrome
Published 2021-01-01“…This review provides an overview of the molecular mechanisms of endometrial function in women with this pathology. Analysis of the literature data found that women with PCOS have changes in the effects of estrogen and progesterone in the endometrium, violation of the spatial and temporal expression of steroid receptors. …”
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Hierarchical regulation of functionally antagonistic neuropeptides expressed in a single neuron pair
Published 2024-11-01“…Our findings suggest that peptidergic autocrine motifs, exemplified by the interaction between NLP-10 and FLP-1, might represent a widespread mechanism in nervous systems across species. These mutual functional interactions among peptidergic co-transmitters could fine-tune brain activity.…”
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Expression changes and functional role of GPR110 in metabolic dysfunction-associated steatohepatitis
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Ovarian expression of functional MTTP and apoB for VLDL assembly and secretion in chickens
Published 2025-05-01“…Following identifications of MTTP and ApoB expression within chicken ovarian stroma, granulosa, theca, and epithelial cells of various classes of follicles, we sought to define the functionality of ovarian MTTP and ApoB in VLDL assembly. …”
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PCPE2: Expression of multifunctional extracellular glycoprotein associated with diverse cellular functions
Published 2024-11-01“…Due to the many similarities between the two related proteins, PCPE2 has been assumed to have biological functions similar to PCPE. PCPE is a well-established enhancer of procollagen processing activating the enzyme, BMP-1. …”
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Impact of Heat Stress on Ovarian Function and circRNA Expression in Hu Sheep
Published 2025-07-01“…Climate change poses an increasing threat to livestock reproduction, with heat stress (HS) known to significantly impair ovarian function. This study aimed to elucidate the impact of HS on ovarian function and circRNA expression profiles in Hu sheep. …”
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Functional analysis of human hematopoietic stem cell gene expression using zebrafish.
Published 2005-08-01“…Overall, this high-throughput screen for the functional validation of differentially expressed genes using a zebrafish model of hematopoiesis represents a major step toward obtaining meaningful information from global gene profiling of HSCs.…”
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Insulin gene expression and functional activity of insulin signaling pathway in Alzheimer's disease
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Correlation between LSM1 Expression and Clinical Outcomes in Glioblastoma and Functional Mechanisms
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Temporal expression classes and functions of vaccinia virus and mpox (monkeypox) virus genes
Published 2025-04-01Subjects: Get full text
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Expression and functional characterization of His-tagged prestin in Chinese hamster ovary cells.
Published 2024-01-01“…Although expression levels were 1/60-1/30 of those in OHCs, cell line maintaining the stable expression of functional prestin with His tag will be advantageous for future analyses of its structure and function.…”
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