The impact of internet pornography addiction on brain function: a functional near-infrared spectroscopy study by Qicheng Shu, Qicheng Shu, Shiyu Tang, Zhenhua Wu, Jiahuan Feng, Wenhao Lv, Min Huang, Fan Xu

“…Participants completed the Stroop Color and Word Task (SCWT) before and after they had watched the video. Facial expressions and life signs were measured continuously during the experiment.ResultsCompared with the group that frequently viewed pornographic videos, the group with low-frequency pornography viewing exhibited enhanced functional connectivity in the inferior prefrontal cortex and pars triangularis of Broca’s area in the frontal lobe, the primary somatosensory cortex in the parietal lobe, and the pre-motor and supplementary motor cortices. …”
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Genome-wide identification and expression analysis of E3 ubiquitin-protein ligase U-box family in Physcomitrium patens by WU Xiaoai1, JIANG Shan1, CHEN Bo2, YAN Huiqing1*

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Expression levels of T cell-related immune factors and their correlation with thyroid function in Graves’ disease with varied serum iodine status: insights into immunopathogenesis by Lilan Wang, Zixuan Ru, Shengnan Gao, Na Lv, Kerou Li, Hong Qiao

“…ObjectiveMeasurement of Serum Iodine Concentration (SIC) in Newly Diagnosed Adult Graves’ Disease (GD) Patients with Hyperthyroidism and Healthy Controls: Investigating Cytokine Expression Profiles and Their Correlations with Thyroid Function Across Diverse Iodine Nutritional Status.MethodPatients newly diagnosed with GD hyperthyroidism from September 2024 to February 2025 at our institution were enrolled. …”
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Deciphering the molecular landscape of dengue infection: Insights from gene expression profiling and Protein Interactions by Afaf S. Alwabli

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Genome-wide identification, expression patterns and functional analysis of TALE (Three Amino-Acid Loop Extension) transcription factors in Arabidopsis thaliana by Hina Ali, Yanhui Liu, Syed Muhammad Azam, Mayra Ahmad, Mengtian Pei, Stefan Olsson, Riaz Ullah, Abdelaaty A. Shahat

“…RNA-seq data revealed that some TALE genes were highly expressed in response to abiotic stresses. Furthermore, a functional study of the TALE gene (knat3) showed a significant reduction in silique length, seed set and weak plant stature. …”
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Genome-wide identification and functional characterization of the LBD transcription factor gene family in Zanthoxylum armatum DC. reveal its potential role in leaf variation by Yifei Deng, Chong Sun, Xueqian Fu, Yuan Guo, Yongxing Zhu, Chongyu Liu, Ruxin Xu, Han Liu, Qiang Li, Ning Tang, Mi Kuang, Wenying Yang, Xia Liu, Zexiong Chen

“…Conclusions In this study, we comprehensively analyzed the functional characteristics and expression patterns of genes in the LBD family within the heterophyllous plant Z. armatum distributed at different latitudes. …”
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Genome-wide analysis of RAD23 gene family and a functional characterization of AcRAD23D1 in drought resistance in Actinidia by Xiaoli Zhang, Daolin Ye, Xueling Wen, Xinling Liu, Lijin Lin, Xiulan Lü, Jin Wang, Qunxian Deng, Hui Xia, Dong Liang

“…UBL-UBA protein functions as a shuttle factor in the 26S ubiquitin degradation pathway, playing a critical role in plant growth and development, and responding to various biotic and abiotic stresses. …”
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PEDF-Expressing mesenchymal stem cells restore ovarian function via Tim-3-Mediated immune modulation in primary ovarian failure by Seyida Yimamuyushan, Song Shi, Aikeremujiang Muheremu, Jinling Yi

“…Conclusion This study demonstrates that PEDF-engineered BMSCs rejuvenate ovarian function by dual mechanisms: enhancing Treg-mediated immune tolerance via the Tim-3/Gal-9 axis and promoting follicular survival. …”
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Analysis of the expression profile and biological function of plasma miRNAs in chronic lymphocytic leukemia and multiple myeloma patients occupationally exposed to pesticides by Luiza Flavia Veiga Francisco, Willian Garcia Birolli, Welinton Hirai, Caroline Rocha Nunes, Iara Zapparoli Gonçalves, Fabiana de Lima Vazquez, Álvaro José dos Santos Neto, Fernando Barbosa Junior, Márcia Maria Chiquitelli Marques, Henrique C.S. Silveira

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The Class III Peroxidase Gene Family in <i>Populus simonii</i>: Genome-Wide Identification, Classification, Gene Expression and Functional Analysis by Lu Han, Yishuang Ren, Xinru Bi, Guowei Yao, Jinwang Zhang, Hongtao Yuan, Xiaoyu Xie, Junbo Chen, Yunchang Zhang, Sitong Du, Wanying Chen, Kewei Cai, Xiyang Zhao

“…Notably, <i>PsPOD45</i>, <i>PsPOD69</i>, <i>PsPOD33</i>, and <i>PsPOD64</i> were identified as central hub genes in the protein–protein interaction network, making them promising candidates for further functional characterization. Overall, this study provides a comprehensive overview of the <i>PsPOD</i> gene family in <i>P. simonii</i>, laying a solid foundation for future functional studies and offering valuable insights for comparative research in other plant species.…”
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Cripto-1 and Cripto-3 differential expression pattern in human placenta, umbilical cord and fetal tissues suggests new functions for these proteins by Josune García-Sanmartín, Judit Narro-Íñiguez, María José Puente, Frank Cuttitta, Alfredo Martínez

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Regulation, Function, and Expression of Matrix Metalloproteinase-9 in Colon, Lung, and Breast Cancers In Silico and Experimental Methods From Iraqi Metastatic Patients by Hamad Hamad Ali, Shakir Yamama Farouk, Zaidan Omar Tareq, Rafea Aymen Adnan, Md Hashim Nur Fariesha

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Relationship of the expression of calcium-handling proteins in the sarcoplasmic reticulum with polymorphic variants of their genes and with structural and functional parameters of the heart in patients with atrial fibrillation by D. S. Kondratieva, S. A. Afanasiev, E. F. Muslimova, E. A. Archakov, R. E. Batalov

“…To investigate the relationship between the expression of Ca2+ handling proteins of the sarcoplasmic reticulum, polymorphic variants of their genes, and structural and functional parameters of the heart in patients with atrial fibrillation (AF).Materials and methods. …”
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Multi-tissue analysis of co-expression networks by higher-order generalized singular value decomposition identifies functionally coherent transcriptional modules. by Xiaolin Xiao, Aida Moreno-Moral, Maxime Rotival, Leonardo Bottolo, Enrico Petretto

“…Analyses of seven rat tissues identified a multi-tissue subnetwork of co-expressed heat shock protein (Hsp) and cardiomyopathy genes (Bag3, Cryab, Kras, Emd, Plec), which was significantly replicated using separate failing heart and liver gene expression datasets in humans, thus revealing a conserved functional role for Hsp genes in cardiovascular disease.…”
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Effect of epigallocatechin-3-gallate (EGCG) on cognitive functioning and the expression of APP and BDNF in the hippocampus of rats with streptozotocin -induced Alzheimer-like disease by Farnaz Ghayour Babaei, Ehsan Saburi, Fatemeh Forouzanfar, Mohadese Asgari, Zakieh Keshavarzi, Vahid Hajali

“…STZ disrupted the function of animals in MWM acquisition phase by almost 65 % and all doses of EGCG could return the learning parameters to those of control animals. …”
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Crohn’s Disease-associated variant in laccase domain containing 1 (LACC1) modulates T cell gene expression, metabolism and T cell function by Yingcong Li, Gabriel Ascui, Martina Dicker, Thomas Riffelmacher, Vivek Chandra, Benjamin Schmiedel, Ting-Fang Chou, Pandurangan Vijayanand, Mitchell Kronenberg

“…We previously found this site near LACC1 was associated with decreased LACC1 expression in T lymphocytes, yet the mechanism affecting gene expression and its links to T cell function and inflammatory disease were unknown. …”
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TACSTD2 in gelatinous drop-like corneal dystrophy: variant functional analysis and expression in the cornea after limbal stem cell transplantation by Liubov O. Skorodumova, Ekaterina N. Grafskaia, Daria D. Kharlampieva, Dmitry I. Maltsev, Tatiana V. Petrova, Alexandra V. Kanygina, Elena V. Fedoseeva, Pavel V. Makarov, Boris E. Malyugin

“…GDLD is characterized by the loss of barrier function in corneal epithelial cells (CECs) and amyloid deposition due to pathogenic variants in the TACSTD2 gene. …”
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The non-metabolic function of 6PGD coordinates CCNA2 and HMGA2 expression to drive colorectal cancer progression and drug response by Mingming Sun, Qi Yan, Xinru Zhai, Xintong Dai, Chenxin Yang, Huifang Zhao, Sizhen Lai, Jiyan Wang, Lian Li, Zhen Li, Yanping Li, Taoyuan Wang, Tao He, Jun Xue, Zhenghu Jia, Chunze Zhang, Shuai Zhang, Changliang Shan

“…Abstract Emerging evidence demonstrates that the metabolic and non-metabolic functions of metabolic enzymes play a key role in tumorigenesis and progression. 6-phosphogluconate dehydrogenase (6PGD) is a key metabolic enzyme in the pentose phosphate pathway (PPP), which displays aberrant expressions and functions in cancer. …”
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The expression profile analysis and functional prediction of lncRNAs in peripheral blood mononuclear cells in maintenance hemodialysis patients developing heart failure by Xing Qi, Lin Yu, Shuai Liu, Yujiao Zhou, Wenqing Liu, Wei Liao, Qin Guo, Xuhui Song, Jifeng Li, Sheng Lin, Chuanqiang Dai, Lin Yan, Tao Li, Li Zhang, Shucheng Zhao, Juan Tang, Jian Cai, Zejiang Liu, Ran Zhu, Q.-Y. Long, Huaguo Wang

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RBM47 functions as an anti-oncogene by regulating expression and alternative splicing of cell proliferation and apoptosis associated genes in colorectal cancer cells by Guangshi Liu, Tao Li, Peng Li, Suyan Wei, Kamuran Abulizi

“…In summary, our results demonstrated the anti-tumor function and the globally downstream targets of RBM47 in CRC cells. …”
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