Morphometric indicators of wound bone tissue condition after surgical treatment of spontaneous periodontitis accompanied by different functional state of organism reactivity by Yu. Yu. Yarov

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25-Hydroxycholecalciferol Improves Cardiac Metabolic Adaption, Mitochondrial Biogenetics, and Redox Status to Ameliorate Pathological Remodeling and Functional Failure in Obese Chi... by Shih-Kai Chiang, Mei-Ying Sin, Jun-Wen Lin, Maraddin Siregar, Gilmour Valdez, Yu-Hui Chen, Thau Kiong Chung, Rosemary L. Walzem, Lin-Chu Chang, Shuen-Ei Chen

“…Necropsy with the surviving counterparts along the time course confirmed alleviation of myocardial remodeling and functional failure by 25-OH-D3, as shown by BNP and MHC-β expressions, pathological hypertrophy, and cardiorespiratory responses (<i>p</i> < 0.05). 25-OH-D3 mitigated cardiac deficient bioenergetics in Ad-hens by rescuing PGC-1α activation, mitochondrial biogenesis, dynamics, and electron transport chain complex activities, and metabolic adaptions in glucose oxidation, pyruvate/lactate interconversion, TCA cycle, and β-oxidation, as well as in TG and ceramide accumulation to limit lipotoxic development (<i>p</i> < 0.05). …”
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The physiological comparison revealed the importance of focusing anti-oxidation function during the peak laying stage in hens based on multi-omics analysis by Yumeng Wang, Xi Sun, Xiaoying Liu, Chaohui Wang, Zhouzheng Ren, Xin Yang, Xiaojun Yang, Yanli Liu

“…Among down-regulated metabolites, hesperetin, apigenin and betaine related to anti-oxidant function were down-regulated. In addition, western blotting result showed BCL2 and p53 proteins expressions were decreased in the peak laying period, whereas hepatic CEBPα protein level was increased. …”
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Prognostic and functional role of PPAR-alpha and SNP receptor (Leu162Val) in acute coronary syndrome: a potential novel target by Abdullah Abdulsattar Raeef, Hassan H. Al-Saeed, Sami Mekhlif Mishlish

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Dosador mecânico de precisão para sementes miúdas: Testes funcionais Precision mechanical seed meter for small seeds: Functional tests by Ângelo V. dos Reis, Fernando A. Forcellini

“…This paper presents the results obtained during the tests of the prototype of a seed meter consisting of a vertical double-face mechanical cylinder, concerning its functional performance in metering and placing rice seeds. …”
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Assessment of the abdominal wall function after pedicled TRAM flap surgery for breast reconstruction: Use of modified mesh repair for the donor defect by Chacko Cyriac, Ramesh Kumar Sharma, Gurpreet Singh

“…This study has been undertaken to assess the abdominal wall function in patients with pedicled TRAM flap breast reconstruction. …”
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Assessment of the abdominal wall function after pedicled TRAM flap surgery for breast reconstruction: Use of modified mesh repair for the donor defect by Cyriac Chacko, Sharma Ramesh, Singh Gurpreet

“…This study has been undertaken to assess the abdominal wall function in patients with pedicled TRAM flap breast reconstruction. …”
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Clostridium butyricum enhances cognitive function in APP/PS1 mice by modulating neuropathology and regulating acetic acid levels in the gut microbiota by Ye Shiqing, Lu Xinjie, Zhu Xiaotong, Chen Jiayan, Lu Jiahai, Chen Xiaodong, Lou Yongliang, Li Xiang

“…In APP/PS1 mice, CBM588 improved cognitive function and alleviated colonic tissue pathology by modulating tight junction proteins (upregulating Claudin 1, ZO-1, and Occludin) and reducing inflammatory cytokines (IL-6, IL-1β, and TNF-α mRNA). …”
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Identification and Functional Characterization of a Novel <i>SOX4</i> Mutation Predisposing to Coffin–Siris Syndromic Congenital Heart Disease by Zi Yan, Bin-Bin Dong, Yan-Jie Li, Chen-Xi Yang, Ying-Jia Xu, Ri-Tai Huang, Xing-Yuan Liu, Yi-Qing Yang

“…The nonsense variation was absent from 262 healthy controls. Functional analysis demonstrated that the Glu111*-mutant SOX4 lost transactivation on <i>NKX2.5</i> and <i>GATA4</i>, two well-established genes that are causative factors for CHD. …”
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Study of heart rate variability in healthy humans as a function of age: considerations on the contribution of the autonomic nervous system and the role of the sinoatrial node by David A. Jorge Tasé, David A. Jorge Tasé, Leopoldo Garavaglia, Magdalena M. Defeo, Isabel M. Irurzun

“…We studied the behavior of the heart rate variability (HRV) in healthy humans as a function of age from conception, including fetal data. …”
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Exposure-response functions of the correlated environmental exposures green space, noise, and air pollution for quantifying mortality burden in health impact assessment by Xuan Chen, Ulrike Gehring, Georgia M.C. Dyer, Kees de Hoogh, Sasha Khomenko, Haneen Khreis, Natalie Mueller, Roel Vermeulen, Harry Williams, Belen Zapata-Diomedi, Mark Nieuwenhuijsen, Gerard Hoek

“…Objective: Environmental health impact assessments (HIA) on green space, air pollution (fine particulate matter (PM2.5) or nitrogen dioxide (NO2)), and noise use exposure–response functions (ERF) based on single-exposure models from epidemiological studies, not accounting for potential confounding by other commonly correlated exposures. …”
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Combined proteomics and metabolomics analysis reveal the effect of a training course on the immune function of Chinese elite short‐track speed skaters by Tieying Li, Jing Shao, Nan An, Yashan Chang, Yishi Xia, Qi Han, Fenglin Zhu

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Functional analysis of African Xanthomonas oryzae pv. oryzae TALomes reveals a new susceptibility gene in bacterial leaf blight of rice. by Tuan T Tran, Alvaro L Pérez-Quintero, Issa Wonni, Sara C D Carpenter, Yanhua Yu, Li Wang, Jan E Leach, Valérie Verdier, Sébastien Cunnac, Adam J Bogdanove, Ralf Koebnik, Mathilde Hutin, Boris Szurek

“…Next, to address contribution to virulence, nine TAL effector genes from the Malian Xoo strain MAI1 and four allelic variants from the Burkinabe Xoo strain BAI3, thus representing most of the TAL effector diversity in African Xoo strains, were expressed in the TAL effector-deficient X. oryzae strain X11-5A for gain-of-function assays. …”
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Synthesis and properties of starch-g-poly(maleic anhydride-co-vinyl acetate)

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Voluntary Activity Wheel Running Improves Hyperammonaemia‐Induced Skeletal Muscle Molecular and Metabolic Perturbations in Mice by Annette Bellar, Avinash Kumar, Khaviyaa Chandramohan, Saurabh Mishra, Muaz Alsabbagh‐Alchirazi, Artem Astafev, Pugazhendhi Kannan, Amy Attaway, Roman Kondratov, Thomas Jaramillo, Lopa Mishra, Takhar Kasumov, Nicole Welch, Srinivasan Dasarathy

“…Results Gastrocnemius muscle mass (p < 0.01), muscle fibre area (p < 0.01), and grip strength were lower in AmAc‐UA than in PBS‐UA mice and higher with VWR than UA in AmAc mice (p < 0.001). Expression of electron transport chain proteins and some components of mitochondrial oxidative function were less (p < 0.05 or less) in AmAc‐UA than PBS‐UA, and these perturbations were reversed in the AmAc‐VWR mice (p < 0.05 or less). …”
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Exploring sphingolipid metabolism-related biomarkers for Parkinson’s disease: a transcriptomic analysis by Guohong Wang, Xingnan Zhou, Xingnan Zhou

“…Based on this, three methods, including functional similarity analysis, co-expression analysis, and gene set enrichment analysis (GSEA) were conducted to study the functions of biomarkers. …”
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Research Progress on Protective Effect of Royal Jelly on the Cardiovascular System by ZHU Wenzhen, CUI Can, ZHAO Xin, XUAN Hongzhuan

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A fixed point approach to predator-prey dynamics via nonlinear mixed Volterra–Fredholm integral equations in complex-valued suprametric spaces by Afrah Ahmad Noman Abdou

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Exercise improves pulmonary fibrosis and neurological symptoms via S100A12 inhibition by Yan Sun, Yan Sun, Meng Li, Meng Li, Jingmin Yuan, Jingmin Yuan, Wenrui Li, Hongli Quan, Yan Li, Zhenjing Kang, Hao Cheng, Hui Ren, Mingwei Chen

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Exposure to 6-PPD Quinone Disrupts Adsorption and Catabolism of Leucine and Causes Mitochondrial Dysfunction in <i>Caenorhabditis elegans</i> by Wei Wang, Yunhui Li, Dayong Wang

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