The effects of Astragalus, Epimedium, and Fructus Ligustri Lucidi extract on the antioxidant capacity, and immune status of goslings under stress conditions by Qing Qu, Qing Qu, Qing Qu, Yihong Sun, Yihong Sun, Yihong Sun, Yayan Liang, Yayan Liang, Yayan Liang, Yongsheng Nie, Yongsheng Nie, Yongsheng Nie, Yongsheng Nie, Ming Gao, Ming Gao, Ming Gao, Yaohui Yuan, Wei Wang, Wei Wang, Wei Wang, Shuo Zhou, Shuo Zhou, Shuo Zhou

“…The effects of Astragalus, Epimedium, and Fructus Ligustri Lucidi (AEF) extract on the immune function, antioxidant capacity, meat quality, intestinal morphology, and intestinal barrier integrity of goslings were investigated. …”
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Proline dehydrogenase, a rate-limiting catabolic enzyme, affecting the growth and pathogenicity of Toxoplasma gondii tachyzoites by regulating the proline metabolism and mitochondr... by Xiao-Ling Geng, Jing-Yu Li, Huan-Yu Xu, Jiang-Ping Wu, De-Liang Tao, Jin-Ming Chen, Ying-Ying Fan, Xin Yang, Jun-Ke Song, Guang-Hui Zhao

“…Conclusions The present study found the significance of the Tgprodh gene for the intracellular growth and pathogenicity of T. gondii through regulating mitochondrial function and the proline metabolism and provided a novel insight to reveal intracellular survival strategies of T. gondii. …”
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Аmygdala DEGs are associated with the immune system function: A comparative transcriptomic study of high- and low-excitability rat strains. by Irina Shalaginova, Marina Pavlova, Natalia Dyuzhikova

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Effect of low-energy extracorporeal shock wave on vascular regeneration after spinal cord injury and the recovery of motor function [Retraction] by Wang L, Jiang YQ, Jiang Z, Han LZ

“…Effect of low-energy extracorporeal shock wave on vascular regeneration after spinal cord injury and the recovery of motor function. Neuropsychiatr Dis Treat. 2016 Aug 31;12:2189–2198. doi: 10.2147/NDT.S82864.This article was found to have plagiarized the content of:Low-energy extracorporeal shock wave therapy promotes vascular endothelial growth factor expression and improves locomotor recovery after spinal injury published in the Journal of Neurosurgery in 2014 (J Neurosurg. 121: 1514–1525, 2014).Accordingly, Dr Pinder, Editor-in-Chief of Neuropsychiatric Disease and Treatment has decided to issue a Retraction notice and advise the academic supervisors of Dr Wang et al of this matter.…”
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Genetic Ablation of Soluble TNF Does Not Affect Lesion Size and Functional Recovery after Moderate Spinal Cord Injury in Mice by Ditte Gry Ellman, Matilda Degn, Minna Christiansen Lund, Bettina Hjelm Clausen, Hans Gram Novrup, Simon Bertram Flæng, Louise Helskov Jørgensen, Lujitha Suntharalingam, Åsa Fex Svenningsen, Roberta Brambilla, Kate Lykke Lambertsen

“…We previously demonstrated that epidural administration of a dominant-negative inhibitor of solTNF, XPro1595, to the contused spinal cord resulted in changes in Iba1 protein expression in microglia/macrophages, decreased lesion volume, and improved locomotor function. …”
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Prenatal methadone exposure produces functional and molecular alterations in the basolateral amygdala and decreased voluntary ethanol intake in female, but not male offspring by Meredith E. Gamble, Michelle Montero, Dana N. Silberstein, Terrence Deak, Terrence Deak, Elena I. Varlinskaya, Elena I. Varlinskaya, Marvin R. Diaz, Marvin R. Diaz

“…PME increased glutamate transmission and altered dopamine D1, D2, and D3 receptor and mu opioid receptor mRNA in the BLA of females, but not in males.DiscussionCollectively, this study identified impairments in emotion and reward processing, in addition to alterations in synaptic function and gene expression in the BLA of females with a history of PME, supporting previous findings from our lab demonstrating that female offspring are more sensitive to the long-term effects of PME.…”
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PTGER4 signaling regulates class IIa HDAC function and SPINK4 mRNA levels in rectal epithelial cells by Murugadas Anbazhagan, Garima Sharma, Shanta Murthy, Sushma Chowdary Maddipatla, Vasantha L. Kolachala, Anne Dodd, Amanda Randunne, David J. Cutler, Subra Kugathasan, Jason D. Matthews

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Effect of exercise training on cardiac function and glucose metabolism in the ischemic border zone: insights from multi-modal imaging techniques by Jun Zhang, Jun Zhang, Jun Zhang, Chunrong Jin, Xiao Han, Xiao Han, Ping Wu, Ping Wu, Jianbo Cao, Jianbo Cao, Jianbo Cao, Sheng He, Sheng He, Li Li, Li Li, Ruonan Wang, Ruonan Wang, Min Zhang, Min Zhang, Yuxin Xiao, Yuxin Xiao, Hongju Guo, Tianshuo Zhang, Zhifang Wu, Zhifang Wu, Zhifang Wu, Sijin Li, Sijin Li, Sijin Li

“…RNA sequencing demonstrated upregulation of pathways associated with cellular metabolism. Additionally, the expression levels of GLUT4 and PFKFB3 mRNA and proteins were significantly elevated following exercise training.ConclusionsEarly exercise post-AMI, as assessed by CMR and PET imaging, significantly improved cardiac function, reduced myocardial remodeling, and enhanced glucose metabolism. …”
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The N-Terminal GYPSY Motif Is Required for Pilin-Specific Sortase SrtC1 Functionality in Lactobacillus rhamnosus Strain GG. by François P Douillard, Pia Rasinkangas, Arnab Bhattacharjee, Airi Palva, Willem M de Vos

“…We investigated the function and role of the GYPSY residues by directed mutagenesis in homologous (rod-shaped) and heterologous (coccoid-shaped) expression systems for pilus formation. …”
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Spatial transcriptomic and morpho-functional information derived from single mouse FFPE slides allows in-depth fingerprinting of lung fibrosis by Erica Ferrini, Costanza Bonfini, Giovanna Marchese, Martina Buccardi, Matteo Zoboli, Primetta Faccioli, Nicola Sverzellati, Gino Villetti, Simone Ottonello, Maria Ravo, Franco F. Stellari

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Metformin-Enhanced Secretome from Periodontal Ligament Stem Cells Promotes Functional Recovery in an Inflamed Periodontal Model: In Vitro Study by Han Na Suh, Ju Young Ji, Jung Sun Heo

“…Here, we aimed to assess the composition of CM from periodontal ligament stem cells (PDLSCs) grown in metformin-preconditioned media (Met-CM) compared to normal PDLSC-CM and assess the ability of Met-CM to recover the function of inflamed PDLSCs. Methods: Met-CM and normal CM were collected from PDLSCs grown with or without 50 µM metformin, respectively, under healthy culture conditions. …”
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Effect of Sulfated Polysaccharides from Brown Alga Fucus evanescens and Their Enzymatic Transformation Product on Functional Activity of Innate Immunity Cells by T. A. Kuznetsova, T. P. Smolina, N. N. Besednova, A. S. Silchenko, T. I. Imbs, S. P. Ermakova

“…The effect of sulfated polysaccharides (PS) from brown alga Fucus evanescens and their enzymatic transformation and low molecular weight product on the functional activity of the innate immunity cells, i.e. polymorphonuclear leukocytes of human peripheral blood (NF) was comparatively studied. …”
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CD11c-Specific Deletion Reveals CREB as a Critical Regulator of DC Function during the Germinal Center Response by Kim Ohl, Anastasia Schippers, Klaus Tenbrock

“…In conclusion, we demonstrate that CREB expression in CD11c+ cells enhances germinal center responses, most likely by altering DC function, which might have implications for autoimmune diseases that are associated with dysregulated GC responses.…”
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Colonic bacterial community responding to selenium-enriched yeast supplementation associated with improved gut mucus function in growing-finishing pigs by Lingling Su, Hongbo Yi, E Xu, Mingfei Xiao, Yanhua Gao

“…In conclusion, SeY doses of 0.3 mg/kg have beneficial effects on intestinal health, whereas prolonged SeY doses up to 5 mg/kg may compromise the intestinal mucus function in growing-finishing pigs.…”
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Identification and functional characterization of the BnRAP2.3.2 promoter in rapeseed (Brassica napus L.) for waterlogging stress tolerance by Xian Tan, Yan Zhou, Yong Cheng, Ali Raza, Yan Lv, Youping Chen, Dan Luo, Liu Zeng, Xiaoyu Ding, Xiling Zou

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CD8+ T cells in breast cancer tumors and draining lymph nodes: PD-1 levels, effector functions and prognostic relevance by Carolina Abrate, Fernando P. Canale, Sabrina N. Bossio, Jimena Tosello Boari, María C. Ramello, Nicolas Nuñez, Wilfrid Richer, Christine Sedlik, Jordan Denizeau, Anne Vincent-Salomon, Edith Borcoman, Andres Del Castillo, Adriana Gruppi, Eva V. Acosta Rodríguez, Eliane Piaggio, Carolina L. Montes

“…Here, we evaluated CD8+ T cells expressing different levels of PD-1, their functional status, and distribution in different tissues of luminal breast cancer (BC) patients. …”
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Effects of energy density of diets and dietary Pediococcus acidilactici supplementation on productive performance, egg quality, and intestinal function in laying hens by Airong Dong, Xuemei Ding, Jianping Wang, Qiufeng Zeng, Shiping Bai, Yue Xuan, Shanshan Li, Sharina Qi, Xiaojuan Bi, Chao He, Keying Zhang

“…The objective of this study was to evaluate the effects of supplementing Pediococcus acidilactici CNCM I-4622 MA 18/5 M (PA) into diets with two energy levels on the production performance and intestinal function of Lohmann pink laying hens from 49 to 65 weeks of age. …”
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Phase separation of a PKA type I regulatory subunit regulates β-cell function through cAMP compartmentalization. by Ha Neul Lee, Julia C Hardy, Emily H Pool, Jin-Fan Zhang, Su Hyun Kim, William F Buhl, Jessica G H Bruystens, Sohum Mehta, Susan S Taylor, Jin Zhang

“…By combining CRISPR-based RIα knockout with an RIα mutant (Y122A) that exhibits defective cAMP-induced LLPS, we demonstrate that RIα LLPS drives cAMP compartmentalization to tune β cell Ca2+ and cAMP oscillation frequency, control insulin secretion, regulate CREB-mediated gene expression and prevent uncontrolled proliferation. Our data establish the Y122A mutant as a selective molecular tool for studying RIα LLPS and expand our understanding of the functional impact of LLPS-driven protein assemblies.…”
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Functional Outlook of <i>Penicillium digitatum PdMFS6</i> Transporter to Elucidate Its Role in Fungicide Resistance and Virulence by Paloma Sánchez-Torres

“…A novel <i>Penicillium digitatum</i> MFS transporter, PdMFS6 (PDIP_42530), was recognized, and its function was studied to explain its relevance in the simultaneous development of resistance to different fungicide spectrums. …”
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Nonlinear static and dynamic buckling of eccentrically stiffened functionally graded cylindrical shells under axial compression surrounded by an elastic foundation by Vu Hoai Nam, Nguyen Thi Phuong, Dao Huy Bich, Dao Van Dung

“… This paper presents an analytical approach to investigate the nonlinear buckling of imperfect eccentrically stiffened functionally graded thin circular cylindrical shells subjected to axial compression and surrounded by an elastic foundation. …”
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