Effect and mechanism of HER2 antibody-drug conjugate combined with anti-PD-1 antibody in mouse bladder cancer models by HE Shuo, TAO Lu, WU Yue

“…Objective‍　‍To investigate the synergistic therapeutic effects of HER2 antibody-drug conjugate (HER2-ADC) combined with anti-PD-1 antibody (anti-PD-1) on HER2-expressing bladder cancer and elucidate its regulatory mechanisms on the tumor immune microenvironment. …”
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Mixed teff (Eragrostis tef, Poaceae) cultivation and consumption among smallholder farmers in South Wollo Zone, Ethiopia by Daniel Melese, Zemede Asfaw, Zerihun Woldu, Bikila Warkineh, Endale Amare, Alex C.  McAlvay, Morgan Ruelle

“…The same proportion asserted preference for varietal mixtures over pure brown or white varieties on account of nutritional benefits and non-food domestic functions. The varietal mixture was also top-ranked by key informants for drought and disease resistance, resilience, and ecological elasticity. …”
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Serotonin blood level study, anxiety-depressive states indicators and patients life quality after laparoscopic treatment of gastroesophageal reflux disease by Ye. I. Haidarzhi

“…The dynamics of serotonin levels correspond to the dynamics of the patients number with signs of anxiety and depression before and after surgery in the main group, as well as the improvement in the psychological state of patients after surgery compared to preoperative data on the scales of the “psychological component” of SF-36 health questionnaire: Vitality (VT), Social Functioning (SF), Role-Emotional (RE), Mental Health (MH). …”
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AUDIOVISUALIZATION OF CABARET CULTURE IN SILENT FILMS OF THE 1900s–1920s / АУДИОВИЗУАЛИЗАЦИЯ КУЛЬТУРЫ КАБАРЕ В НЕМОМ КИНО 1900–1920-х by MARTYNOVA DARIA O. / МАРТЫНОВА Д.О.

“…The research findings indicate that early cinema, particularly films featuring cabaret dances, functioned as polycode texts, accumulating blocked or previously experienced memories through actions and images. …”
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WABAH CORONA DAN UNGGAHAN DI INSTAGRAM: ANALISIS KOMPONEN TINDAK TUTUR by Anak Agung Ayu Dian Andriyani, I Gusti Agung Sri Rwa Jayantini

“…The dominant speech act functions found in this study were expressive, commissive, declarative, and directive. …”
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Phenomenon of a regional philosophical school: experience in understanding the activities of V. N. Borisov by T. V. Borisova, V. O. Sheleketa, A. A. Shestakov

“…In this context it seems relevant to consider the social organization of the cognitive process, which can be expressed (1) in a comprehensive study of the mechanisms of functioning of various types of scientific communities (central/regional), (2) analysis of the processes of formation, development and degradation of scientific schools, (3) thematization of issues related to the quantitative and qualitative consolidation of advantages in science (scientific production), (4) establishing the originality of scientific capital and the relationship of the latter with symbolic capital. …”
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B cell c-Maf signaling promotes tumor progression in animal models of pancreatic cancer and melanoma by Hong Li, Shu Li, Jun Yan, Yongling Ning, Hongying Hao, Qian Zhong, Chuanlin Ding, Xiaoling Hu, Kelly M McMasters

“…Additionally, tumor-specific antibodies (Abs) also exhibit antitumor and protumor functions dependent on the Ab isotype. Transcription factor c-Maf has been suggested to contribute to the regulation of IL-10 in Breg, but the role of B cell c-Maf signaling in antitumor immunity and regulating Ab responses remains unknown.Methods Conditional B cell c-Maf knockout (KO) and control mice were used to establish a KPC pancreatic cancer model and B16.F10 melanoma model. …”
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EFFECTIVENESS OF THERAPEUTIC AND PROPHYLACTIC MEASURES IN THE MANAGEMENT OF GENERALISED PERIODONTITIS OF THE INITIAL AND FIRST DEGREE IN PATIENTS WITH ATHEROSCLEROSIS ACCORDING TO... by I.S. Dankevich-Kharchyshyn, T.I. Pupin, N.N. Bandrivska

“…The statistical calculation of the results was performed using Statistica 8.0 (StatSoft, USA) and the statistical functions package of Microsoft Excel 2021. Results and Discussion. …”
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STYLISTIC MEANS OF IMPLEMENTING THE IDEA OF THE WORLD’S IRIDESCENCE IN PH.K. DICK’S “UBIK” IN THE CONTEXT OF TRANSLATION TRANSFORMATIONS by Svitlana F. Aleksenko, Larysa I. Taranenko

“…The method of stylistic analysis was applied to interpret stylistic phenomena inherent in the novel in relation to their contribution to the studied idea as those were found functioning in the relevant textu- al microcontexts and enhancing the aforementioned semantic dominants. …”
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Leveraging Technology to Engage Supplemental Nutrition Assistance Program Consumers With Children at Farmers Markets: Qualitative Community-Engaged Approach to App Development by Callie Ogland-Hand, Jillian Schulte, Owusua Yamoah, Kathryn Poppe, Timothy H Ciesielski, Regan Gee, Ana Claudia Zubieta, Darcy A Freedman

“…We then shared V1 with SNAP consumers, children, and farmers market managers to test the app’s functionality, design, and utility. ResultsIn the “inspiration” phase, the community nutrition partners identified SNAP consumers with children younger than 18 years as the target population for the app. …”
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“Opening the era”: to the 100th anniversary of establishing Soviet weekly magazine "Ogonyok" by A. V. Tantsevova

“…The purpose of the article is to reconstruct, on the basis of various historical sources, the history of the creation and functioning of the Soviet weekly Ogonyok in the first post-revolutionary decade, to consider its role and place in the system of Soviet periodicals.Materials and methods. …”
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Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells by Chenyang Wang, Moran Yang, Yujing Zhong, Kankan Cao, Xueling Wang, Chen Zhang, Yiying Wang, Mengdi He, Jiaqi Lu, Guodong Zhang, Yan Huang, Haiou Liu

“…We investigated the biological functions of JAG2 in immune evasion using in vitro co‐culture systems, flow cytometry, tumor‐bearing mouse models, and PDTOs. …”
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Comparative genomic analysis of trypanosomatid protists illuminates an extensive change in the nuclear genetic code by Kristína Záhonová, Zoltán Füssy, Amanda T. S. Albanaz, Anzhelika Butenko, Ambar Kachale, Natalya Kraeva, Arnau Galan, Alexandra Zakharova, Bojana Stojanova, Jan Votýpka, Alexei Y. Kostygov, Viktoria V. Spodareva, Marina N. Malysheva, Alexander O. Frolov, Igor B. Rogozin, Zdeněk Paris, Leoš Shivaya Valášek, Vyacheslav Yurchenko, Julius Lukeš

“…This cascade of mutually dependent adaptations, driven by increasing AU-richness in transcripts and frequent emergence of in-frame stops, underscores the dynamic interplay between genome composition and genetic code plasticity to maintain vital functionality.IMPORTANCEThe genetic code, assigning amino acids to codons, is almost universal, yet an increasing number of its alterations keep emerging, mostly in organelles and unicellular eukaryotes. …”
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An optimized integrin α6-targeted peptide capable of delivering toxins for melanoma treatment by Zheng Zhao, Zi-Qian Li, Ying-Bin Huang, Meng-meng Liu, Fei Cao, Guo-Long Bu, Peng-Fei Xu, Qi Fang, Zhu-Long Hu, Di Wu, Guo-Kai Feng, Xue-Kui Liu

“…Methods We developed a new combination strategy for the synthesis of penetrating peptides functionalized with targeting of integrin α6. The linear peptide S5 was multimerized with 4 copies in linear sequential order spaced by GSG between each copy to yield the 4S5 peptide. …”
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A fully human IgG1 antibody targeting connexin 32 extracellular domain blocks CMTX1 hemichannel dysfunction in an in vitro model by Abraham Tettey-Matey, Viola Donati, Chiara Cimmino, Chiara Di Pietro, Damiano Buratto, Mariateresa Panarelli, Alberto Reale, Arianna Calistri, Maria Vittoria Fornaini, Ruhong Zhou, Guang Yang, Francesco Zonta, Daniela Marazziti, Fabio Mammano

“…Abstract Connexins (Cxs) are fundamental in cell–cell communication, functioning as gap junction channels (GJCs) that facilitate solute exchange between adjacent cells and as hemichannels (HCs) that mediate solute exchange between the cytoplasm and the extracellular environment. …”
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Exploring the gut microbiota associated with peripheral nerve invasion in colorectal cancer patients and constructing predictive models by Chuanbin Chen, Qingmin Chen, Shenghai Liu, Guoxi Li, Jiawei Zhao, Jingting Huang, Tianyi Ye, Xinting Yang, Zigui Huang, Zhen Wang, Fuhai He, Mingjian Qin, Chenyan Long, Binzhe Tang, Yongqi Huang, Weizhong Tang, Jungang Liu, Xiaoliang Huang

“…Abstract Objective This study aims to explore the differences in composition, abundance, and biological functions of the gut microbiota between colorectal cancer (CRC) patients with peripheral nerve invasion (PNI) and those without peripheral nerve invasion (NPNI). …”
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Risk of COVID­-19 Infection among Employees of a Large Anti­tuberculosis Institution in Moscow: Survey Results by E. M. Bogorodskaya, I. V. Nozdrevatykh, E. L. Khristoforova, E. M. Belilovsky

“…Studying the experience of working under the conditions of COVID-19 allows us to more effectively assess the functioning of anti-epidemic measures in the event of the occurrence or threat of new pandemics, including those caused by new pathogens. …”
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The role of proline P325 residue in the recognition of the MX35 epitope of the sodium-dependent phosphate transporter NaPi2b by monoclonal antibodies in ovarian carcinoma cells by L. F. Bulatova, I. A. Slidzuk, A. V. Kilunov, V. S. Skripova, R. G. Kiyamova

“…One of the key components of cell membranes are membrane proteins, which provide a wide range of functions – from transport and signal transmission to coordination of intercellular interactions. …”
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SeqSNP-based genic markers reveal genetic architecture and candidate genes for low nitrogen tolerance in tropical maize inbred lines by Pearl Abu, Baffour Badu-Apraku, Beatrice Elohor Ifie, Beatrice Elohor Ifie, John Saviour Yaw Eleblu, Georgina Lala Ehemba, Pangirayi B. Tongoona, Samuel Kwame Offei

“…The genes are involved in several functions including normal growth, tassel meiosis, root architecture, cell proliferation, cell growth, reproduction, and post-embryonic development. …”
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Impact mechanism of anaerobic digestion of sulfur-rich coal to H2S by graphene by Wenjie ZHAO, Xianbo SU, Weizhong ZHAO, Yixuan ZHOU

“…Coalbed Gas Bioengineering (CGB) is a special anaerobic fermentation project, which uses modern engineering techniques to convert coal and CO2 into methane and associated liquid organic matter by using some specific functions of microorganisms. Graphene is regarded as a viable strategy for on-site implementation to enhance the electron transfer rate in anaerobic fermentation systems. …”
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