A novel plasmid-encoded transposon-derived small RNA reveals the mechanism of sRNA-regulated bacterial persistence by Shu-Ling Lin, Qi-Chang Nie, Carmen Oi-Kwan Law, Hoa-Quynh Pham, Ho-Fai Chau, Terrence Chi-Kong Lau

“…ABSTRACT Small regulatory RNAs (sRNAs) in bacteria are crucial for controlling various cellular functions and provide immediate response to the environmental stresses. …”
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Cyanoexosortase B is essential for motility, biofilm formation, and scytonemin production in a filamentous cyanobacterium by Gabriel A. Parrett, Daniel H. Haft, Maida Ruiz, Ferran Garcia-Pichel, Christopher C. Ebmeier, Douglas D. Risser

“…Given the abundance of putative PEP-CTERM proteins encoded in the N. punctiforme genome and the fact that this study only associates a fraction of them with biological functions, it seems likely that CrtB may play an important role in other biological processes in cyanobacteria.IMPORTANCEIn gram-negative bacteria, exosortases facilitate the trafficking of proteins to the exterior of the cell where they have been implicated in stabilizing the association of extracellular polymeric substances (EPS) with the cell surface to facilitate biofilm formation and flocculation, but the role of exosortases in cyanobacteria has not been explored. …”
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Formation of Competences in the Field of Information Security for Future Bachelors of Applied Informatics by I. V. Gavrilova, M. V. Romanova, E. V. Chernova

“…Even though bachelors of applied computer science will not perform the same job functions as information security specialists, their training should be sufficient to enable them to design and build safe and reliable information systems. …”
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Evaluation of the efficacy of enteral therapy in a patient with posttraumatic pancreatitis (clinical case) by M. S. Zhigalova, V. V. Kiselev, S. S. Petrikov, P. A. Yartsev, A. A. Ryk, Yu. S. Teterin, N. V. Shavrina, I. E. Selina, M. M. Rogal, K. V. Staleva

“…In the development of post-traumatic pancreatitis, an important role is played by microcirculatory disorders, developing against the background of inflammation and decreased capillary blood flow not only in the tissues of the pancreas, but also in other organs, including the intestine, which leads to neuroendocrine dysregulation, dysfunction and/or death of intestinal epithelial cells, disruption of the motor and evacuation functions of the intestine, and, as a consequence, the development of intestinal insufficiency syndrome.The objective was to demonstrate the effectiveness of enteral therapy in a patient with a closed abdominal injury, liver injury and posttraumatic pancreatitis.Materials and methods. …”
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A usability evaluation framework for a mobile application in supporting home-based rehabilitation for stroke patients: A qualitative study by Shih-Ying Chien

“…Conclusions Satisfaction and performance surveys and qualitative data analysis revealed that most participants described the interface design of the app as intuitive and easy to use. Although some functions presented challenges, there was still a high level of satisfaction among both groups. …”
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System of National Accounts as an Information Base for Tax Statistics by A. E. Lyapin

“…The procedure for the collection of taxes was necessary for functioning of the political machinery.The article formalizes and substantiates a serious accounting problem related to the terminologically ambiguous interpretation of the categories, applicable in different accounting systems: accounting, tax and statistical accounting. …”
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The Psycholinguistic Aspects of Global Bilingualism Against the Background of the Society Digitalization Process in Ukraine and Slovak Republic by Тетяна Лелека, Олена Москаленко

“…The purpose of the experimental study is to identify the tendencies of the global bilingualism development in the Ukrainian and Slovak languages based on the English loanwords functioning in the individual consciousness of their speakers. …”
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Hydrodynamic and sensitivity analysis of a polymeric calendering process for non-Newtonian fluids with temperature-dependent viscosity by Ali Fateh, Zahid Muhammad, Farmer M., Al Taisan Nada, Faqihi Abdullah A., Souayeh Basma, Raju S. Suresh Kumar, Alam Mir Waqas

“…Additionally, using the response surface method, Nusselt number (Nu)(\text{Nu}), sheet thickness HH0\left(\phantom{\rule[-0.75em]{}{0ex}},\frac{H}{{H}_{0}}\right), and shear stress (Sxy)({S}_{xy}), simulations were carried out to investigate the influence of variable viscoelastic parameters on the response functions (Nu\text{Nu}, HH0\frac{H}{{H}_{0}}, and Sxy{S}_{xy}). …”
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Identification of SNPs and Candidate Genes Associated with Growth Using GWAS and Transcriptome Analysis in Portuguese Oyster (<i>Magallana angulata</i>) by Jingyi Xie, Yue Ning, Yi Han, Caiyuan Su, Xiaoyan Zhou, Qisheng Wu, Xiang Guo, Jianfei Qi, Hui Ge, Yizou Ke, Mingyi Cai

“…By combining GWAS and comparative transcriptome analysis, a total of seven candidate genes were identified, with biological functions related to growth inhibition, stress response, cell cycle regulation, and immune defense. …”
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Oncolytic VSV-IL-2 has enhanced anticancer vaccination adjuvant abilities by Marie-Claude Bourgeois-Daigneault, Victor Mullins-Dansereau, Marie-Lou Myre, Angelina Bardoul, Karen Geoffroy, Marco J Rallo Pita, Delphine Béland, Kim Leclerc Desaulniers, Dominic Guy Roy

“…Treatment efficacy was also measured.Results Our data show that VSV-interleukin-2 is superior as a vaccine boosting adjuvant compared with the parental virus as it induces more antigen-specific CD8 T cells with enhanced effector functions that persist over time. VSV-interleukin-2 vaccination also improves tumor control and survival.Conclusions Overall, we show that engineered oncolytic virus platforms, such as VSV-interleukin-2, have the potential to improve vaccination efficacy and treatment outcomes. …”
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Effects of laminarin on antioxidant capacity and non-specific immunity of spotted sea bass (Lateolabrax maculatus) by Sishun Zhou, Huihui Qin, Zhongying Long, Lumin Kong, Jianrong Ma, Yi Lin, Hao Lin, Zhangfan Huang, Zhongbao Li

“…As a prebiotic, laminarin has functions such as antioxidant and improving the body's immunity. …”
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Calcaratarin D, a labdane diterpenoid, attenuates bleomycin-induced pulmonary fibrosis by blocking Wnt/β-catenin signaling pathway by Wupeng Liao, Yuet Ang, Adrian C.L. Kee, Valencia Lim, Albert Y.H. Lim, Christina L.L. Chai, W.S. Fred Wong

“…In addition, CalD ameliorated lung histopathology, reduced collagen deposition and mucus hypersecretion, and improved lung functions in BLM-exposed mice. Furthermore, CalD modulated the levels of pro-inflammatory cytokines, chemokines, and growth factors in BAL fluid and lung tissues. …”
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Analysis of immunogenic cell death in periodontitis based on scRNA-seq and bulk RNA-seq data by Erli Wu, Xuan Yin, Feng Liang, Xianqing Zhou, Jiamin Hu, Wanting Yuan, Feihan Gu, Jingxin Zhao, Ziyang Gao, Ming Cheng, Shouxiang Yang, Lei Zhang, Qingqing Wang, Qingqing Wang, Xiaoyu Sun, Xiaoyu Sun, Wei Shao, Wei Shao

“…Consensus cluster analysis based on these 5 genes showed that there were differences in immune cells and immune functions among subtypes associated with ICD. Finally, qPCR and immunohistochemistry confirmed the ability of these five genes as biomarkers for the diagnosis of periodontitis.ConclusionFibroblasts may be the main cell source of ICD in periodontitis. …”
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Biophysical mapping of TREM2-ligand interactions reveals shared surfaces for engagement of multiple Alzheimer’s disease ligands by Jessica A. Greven, Joshua R. Wydra, Rory A. Greer, Cynthia Zhi, David A. Price, Jordyn D. Svoboda, Christopher L. M. Camitta, Mya Washington, Daisy W. Leung, Yuhua Song, Jen Alexander-Brett, Tom J. Brett

“…Our findings imply that pharmaceutical strategies targeting these surfaces might be effective to modulate TREM2 functions.…”
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Effects of kelp phlorotannins on the growth, immunity, intestinal health and disease resistance against Vibrio splendidus of sea cucumber Apostichopus japonicus by Zhikai Zhang, Yan Chi, Yongheng Du, Feng Li, Ning Ma, Song Qin

“…Phlorotannins are natural polyphenols from brown seaweed and their health-promoting functions have been identified in mammals. Although the sources of phlorotannins are widely distributed and inexpensive, they were rarely investigated in aquatic animals. …”
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Neoantigen-specific stimulation of tumor-infiltrating lymphocytes enables effective TCR isolation and expansion while preserving stem-like memory phenotypes by Yong Li, Steven A Rosenberg, Paul F Robbins, Zhiya Yu, Maria Parkhurst, Billel Gasmi, Nikolaos Zacharakis, Todd D Prickett, Jared J Gartner, Sri Krishna, Stephanie L Goff, Satyajit Ray, Frank J Lowery, Sivasish Sindiri, Alakesh Bera, Noam Levin, Sanghyun P Kim, Charles A Marquardt, Nolan R Vale, Lior Levy, Tiffany Benzine, Robert V Masi, Rafiqul Islam

“…NeoExpand led to improved phenotypes and functions of neoantigen-reactive TILs. Our data warrant its clinical evaluation.Trial registration number NCT00068003, NCT01174121, and NCT03412877.…”
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Nursing Students' Perspectives on Integrating Artificial Intelligence Into Clinical Practice and Training: A Qualitative Descriptive Study by Moustaq Karim Khan Rony, Sumon Ahmad, Dipak Chandra Das, Sabren Mukta Tanha, Tuli Rani Deb, Mosammat Ruma Akter, Mst. Amena Khatun, Md Ibrahim Khalil, Umme Rabeya Peu, Mst. Rina Parvin, Daifallah M. Alrazeeni, Fazila Akter

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Nursing Educators’ Perspectives on the Integration of Artificial Intelligence Into Academic Settings by Moustaq Karim Khan Rony MSS, MPH, RN, Sumon Ahmad MPH, RN, Sabren Mukta Tanha MPH, RN, Dipak Chandra Das MSS, Mosammat Ruma Akter MSN, RN, Mst. Amena Khatun MPH, RN, Most. Hasina Begum MSN, RN, Md Ibrahim Khalil MSS, RN, Umme Rabeya Peu MSS, RN, Mst. Rina Parvin BSN, RN, Daifallah M Alrazeeni PhD, Fazila Akter MSc, RN

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The essence and structure of the scientific outlook of future teachers of natural and mathematical specialties by Zelinha Yulia, Halitsan Olha

“…The scientificmethodological component of the scientific outlook of the future teacher of natural and mathematical specialties expresses the specialist’s ability to build the plane of professional activity on the correct methodological basis, relying on the formed innovative-professional and methodical-methodological culture. …”
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Signal peptidase SpsB coordinates staphylococcal cell cycle, surface protein septal trafficking, and LTA synthesis by Ran Zhang, Yaosheng Jia, Salvatore J. Scaffidi, Jesper J. Madsen, Wenqi Yu

“…Furthermore, this study highlights the novel functions of SpsB in coordinating LtaS-mediated LTA production and regulating staphylococcal cell cycle. …”
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