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28621
THE PROGRAM OF ADAPTATION AND PROFESSIONAL DEVELOPMENT OF PERSONNEL WITHIN A QUALITY MANAGEMENT SYSTEM OF THE PHARMACEUTICAL ORGANIZATION (REVIEW)
Published 2019-02-01“…In addition, the professional development of staff is an essential condition and key to the successful functioning of the quality system, as well as the efficiency, performance and well-being of the organization as a whole. …”
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28622
Unlocking health insights: exploring intention to adopt district health information systems in Bahir Dar City, northwest Ethiopia
Published 2025-02-01“…Therefore, it is imperative to implement targeted interventions before system rollout, including practice-based training, fostering positive attitudes, and enhancing knowledge of the system's usability and functionality to improve the adoption of the district health information system.…”
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28623
Membrane vesicle production via cell-to-cell communication-induced autolysis in Streptococcus mutans
Published 2025-07-01“…We compared the protein profiles of CMVs, showing that CMVs induced via the Com system contained not only secreted proteins but also cytoplasmic proteins specifically expressed during Com system activation. We further demonstrate that the functionality of CMVs in biofilm formation differed depending on how they were induced.IMPORTANCEBacteria release membrane vesicles (MVs) that are involved in diverse biological processes such as cell-to-cell communication and also affect the bacterial host through their immunomodulatory activity. …”
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28624
Patients’ Experiences With Using a Digital Platform for Chat-Based Consultation in Primary Health Care in Sweden: Qualitative Study
Published 2025-08-01“…ResultsThree main themes emerged: (1) digital technology’s impact on access to services, (2) perceived digital platform functionality and usability, and (3) shifts in the patient-provider dynamic through digital communication. …”
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28625
SIRT6 deficiency impairs the deacetylation and ubiquitination of UHRF1 to strengthen glycolysis and lactate secretion in bladder cancer
Published 2024-12-01“…We thus aimed to study the biological functions of SIRT6 in bladder cancer. Methods Bioinformatic analysis was used to study the prognostic significance of SIRT6/UHRF1 in BLCA. …”
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28626
Health-related quality of life, physical and mental capacity at one year follow up of COVID-19 ICU patients: A prospective cohort study
Published 2025-05-01“…Secondary outcome parameters were clinimetric results for physical, mental, and cognitive functions at 6 months after intensive care stay. Results Data from 41 patients were analyzed. …”
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28627
A Novel Molecular Classification Method for Glioblastoma Based on Tumor Cell Differentiation Trajectories
Published 2023-01-01“…Each cluster exhibited different potential drug sensitivities, pathways, functions, and transcriptional modules. The classification model was further examined in TCGA and CGGA datasets. …”
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28628
The Histidine-25-Arginine Mutation in the Rice MACPF Protein OsCAD1 Induces Cell Death and Activates Defense Responses in the Lesion Mimic Mutant spl17
Published 2025-07-01“…Transcriptome analyses, including RNA-Seq and Gene Set Enrichment Analysis (GSEA), indicate that differentially expressed genes (DEGs) in spl17 are enriched in catalytic activity, metabolic processes, and membrane functions. …”
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28629
Role of PD-1/PD-L1 signaling axis in oncogenesis and its targeting by bioactive natural compounds for cancer immunotherapy
Published 2024-12-01“…Furthermore, it controls the phenotype and functionality of innate and adaptive immune components. …”
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28630
Representation of a Scientific Supervisor in Internet-Memes
Published 2024-04-01“…The concept of visual metaphor and multimodality is defined, the role of multimodal metaphor in Internet discourse is described, the features of the functioning of multimodal metaphor are revealed. The material for the study was Internet memes representing various aspects of interaction in the academic environment. …”
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28631
Człowiek odpowiada sercem na dary Boga
Published 2015-12-01“…This state is due to the fact that already in the hearts of the Gentiles the law had been inscribed that makes proper functioning of conscience (Rom 2:15). The situation becomes even more evident with the adoption of faith in Jesus Christ, for then the love of God was poured out in the hearts of believers (Rom 5:5). …”
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28632
THE GENDER LEADERSHIP AS AN ASPECT OF MANAGING EFFICIENCY IN MEDIA COMPANIES
Published 2021-01-01“…; «why is neither the neoliberal capitalist nor liberal social ideal adequate but functioning nowhere?» During the time of Ukrainian independence, these issues have not been resolved yet. …”
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28633
Le personnage féminin dans «La femme du Caïd» de Fatima BAKHAI: Une (re) construction identitaire
Published 2024-12-01“…This article aims to explore the functioning of this underlying discourse and its power relations, illustrating both the individual identity quest of the female figure and how these dynamics, as well as cultural norms, influence and (re)shape her identity. …”
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28634
Portulaca oleracea (purslane) aqueous extract reduced the adverse metabolic outcomes and favored liraglutide activities in streptozotocin-induced cardiometabolic disorders of male...
Published 2024-09-01“…Portulaca oleracea resulted in reduced plasma fasting blood glucose (FBG), interleukin 6 (IL-6), tumor necrosis factor-alpha (TNF- α) and increased pancreatic beta cell functions (HOMA-B) compared to the diabetic rats (p < 0.05). …”
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28635
New Players in Metabolic Syndrome
Published 2025-06-01“…Additionally, nesfatin-1, which is widely expressed in both central and peripheral tissues, is thought to be involved in various physiological functions beyond appetite control, such as glucose homeostasis, stress response, and cardiovascular health. …”
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28636
The role of exosomal lncRNAs in mediating apoptosis and inflammation in UV-induced skin photoaging
Published 2025-04-01“…The skin, as the body’s largest organ, functions as a vital barrier against environmental insults. …”
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28637
Realización computacional en tres dimensiones del Método de los Elementos de Contorno en la teoría de la Elasticidad // Three dimension computational realization of the Method of t...
Published 2000-03-01“…<br />The computational formulation of the method is based on the discretization of the boundary into elements over which<br />displacements and tractions are expressed in terms of interpolation functions. Applying the collocation method a system of<br />lineal equations is obtained that brings the solution on the boundary, from which the solution in any point of the definition<br />region of the problem can be obtained.…”
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28638
A pH-triggered self-releasing humic acid hydrogel loaded with porcine interferon α/γ achieves anti-pseudorabies virus effects by oral administration
Published 2024-11-01“…Abstract Interferon α (IFNα) and interferon γ (IFNγ) play pivotal roles in mediating crucial biological functions, including antiviral activity and immune regulation. …”
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28639
Human factor of agroecological transition: global guidelines for Ukraine
Published 2025-03-01“…The societal significance of agroecological transformations is also emphasised, since new relations express the interests not only of consumers and producers of environmentally friendly products, but also of the whole society, which is able to enjoy the positive impact of agroecology on various spheres of its functioning, in particular the formation of sustainable and inclusive agri-food systems. …”
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28640
A Novel Framework for Saraiki Script Recognition Using Advanced Machine Learning Models (YOLOv8 and CNN)
Published 2025-01-01“…Linguistics’ fundamental goal is to comprehend how language functions in composition and context. On the other hand, machine learning is the study of how to teach machines to learn and predict using data instead of explicit programming. …”
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