Effect of post-stroke cognitive impairment and dementia on stroke recurrence and functional outcomes: A systematic review and meta-analysis. by Jia Yu, Jie Wang

“…<h4>Introduction</h4>Post-stroke cognitive impairment (PSCI) and dementia may have a significant impact on stroke recurrence and long-term functional outcomes of patients.<h4>Aim</h4>To investigate the potential link between PSCI and dementia, and stroke recurrence, mortality, and poor functional outcomes of stroke survivors.…”
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Conditional knockout of C/EBPβ in epidermis results in dysregulated lipid biosynthesis and a defect in skin barrier function. by Kevin J Mills, Michael Doyle, John S House, John G Witherspoon, Daniel Krakko, Whitney L Stutts, Jessie R Chappel, Jonathan R Hall, Erin S Baker, Robert C Smart

“…Finally, we assessed the functional consequences of the loss C/EBPβ on epidermal barrier function and found that basal permeability barrier function as measured by transepidermal water loss (TEWL) was impaired, with an approximate doubling of TEWL in CKOβ mice. …”
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Functional characterization of cutinase genes NsCut1-NsCut4 in Neostagonosporella sichuanensis and their effects on fishscale bamboo by Mengyao Lu, Mengyao Lu, Fang Liang, Fang Liang, Lijuan Liu, Lijuan Liu, Yanji Yin, Yanji Yin, Dongxin Xu, Dongxin Xu, Huan Zou, Huan Zou, Yinggao Liu, Yinggao Liu, Chunlin Yang, Chunlin Yang

“…Recombinant proteins expressed via a prokaryotic system exhibited strong hydrolytic activity against glycerol tributyrate and bamboo white cream at 40°C and pH 8.0, while signal peptide and subcellular localization analyses confirmed their secretory function and localization to the cell wall. …”
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Transcriptome analysis indicates improved adipose tissue function in growing Iberian pig fed olive by-products based diets by Patricia Palma-Granados, Patricia Palma-Granados, Juan M. García-Casco, Juan M. García-Casco, Ramón Peiró-Pastor, Cristina Óvilo, Miguel A. Delgado, Miguel A. Delgado, Fabián García, Adrián López-García, Adrián López-García, Elena González, María Muñoz

“…Furthermore, in the WCOC diet, functions related to cholesterol and lipid metabolism were repressed. …”
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What do we know about intratumoral functional activity: a scoping review of imaging and intra-surgery results by Ilaria Guarracino, Marta Maieron, Serena D’Agostini, Tamara Ius, Barbara Tomasino

“…Within this framework, we aimed to shed light on some issues, including whether i) it is expressed only as fMRI activation within the mass, or whether it impacts on distant areas via functional connectivity, ii) it is found in slow growing tumors such as low grade glioma or also for fast infiltrative processes such as for high grade glioma, and iii) inhomogeneity of the tumor structure and morphological appearance or the tumor histology are key factors determining intratumoral area functionality. …”
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FUNCTIONAL STATE OF THE MICROCIRCULATION OF THE SKIN ACCORDING TO LASER DOPPLER FLOWMETRY IN PATIENTS WITH ATRIAL FIBRILLATION WHO UNDERWENT CARDIOEMBOLIC STROKE by I. A. Zolotovskaya, I. L. Davydkin, A. A. Fedorovich, O. M. Drapkina

“…The revealed disorders of microcirculatory processes are significantly related with the disturbances of the hemostatic function of the endothelium. From the pathophysiological point of view, that is one of the negative risk factors of the development of recurrent thrombus formation.…”
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Mechanism-based subtyping in binge eating: understanding neurobehavioral heterogeneity across negative emotionality, approach behavior, and executive function by Leyla R. Brucar, Eric Rawls, Ann F. Haynos, Carol B. Peterson, Anna Zilverstand

“…The Approach and Restrained subtypes further demonstrated unique neurobiological profiles, as determined by graph theory analysis of resting-state functional connectivity. All subtypes showed similar proportions of BE episodes meeting clinical-level threshold (≥4 objective binge episodes/month), and no differences in BMI, indicating functionally distinct expressions of BE, beyond clinical severity and diagnostic classification. …”
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Variation in the FFAR1 gene modifies BMI, body composition and beta-cell function in overweight subjects: an exploratory analysis. by Celia G Walker, Louise Goff, Les J Bluck, Bruce A Griffin, Susan A Jebb, Julie A Lovegrove, Thomas A B Sanders, Gary S Frost, RISCK Study Group

“…There were no statistically significant effects of the three SNPs on insulin sensitivity or beta cell function. However accumulated risk allele showed a lower beta cell function on increasing plasma fatty acids with a carbon chain greater than six.…”
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Characterization of gut microbiota and metabolites in renal transplant recipients during COVID-19 and prediction of one-year allograft function by Zijie Wang, Xiang Gao, Hongsheng Ji, Ming Shao, Bin Ni, Shuang Fei, Li Sun, Hao Chen, Ruoyun Tan, Mulong Du, Min Gu

“…Results Four microbial phyla (Deferribacteres, TM7, Fusobacteria, and Gemmatimonadetes) and 13 genera were significantly enriched across three recipients groups, correlating with baseline inflammatory response and allograft function. Additionally, 52 differentially expressed metabolites were identified, with seven significantly correlating with eight altered microbiota genera. …”
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Interactions of the anti-FcRn monoclonal antibody, rozanolixizumab, with Fcγ receptors and functional impact on immune cells in vitro by Omar S. Qureshi, Emma J. Sutton, Rosemary F. Bithell, Shauna M. West, Rona M. Cutler, Gillian McCluskey, Graham Craggs, Asher Maroof, Nicholas M. Barnes, David P. Humphreys, Stephen Rapecki, Bryan J. Smith, Anthony Shock

“…Furthermore, data from in vitro experiments using relevant human cell types that express both FcRn and FcγRI indicated no evidence for functional sequelae in relation to cellular activation events (e.g., intracellular signaling, cytokine production) upon either FcRn or FcγR binding of rozanolixizumab. …”
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Defining the functional domain of programmed cell death 10 through its interactions with phosphatidylinositol-3,4,5-trisphosphate. by Christopher F Dibble, Jeremy A Horst, Michael H Malone, Kun Park, Brenda Temple, Holly Cheeseman, Justin R Barbaro, Gary L Johnson, Sompop Bencharit

“…Combining computational modeling and biological data, we propose that the CCM protein complex functions in the PI3K signaling pathway through the interaction between PDCD10 and PtdIns(3,4,5)P3.…”
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Coefficient Bounds for Alpha-Convex Functions Involving the Linear <i>q</i>-Derivative Operator Connected with the Cardioid Domain by Sudhansu Palei, Madan Mohan Soren, Luminiţa-Ioana Cotîrlǎ

“…Scholars from several disciplines have recently expressed interest in the field of fractional <i>q</i>-calculus based on fractional integrals and derivative operators. …”
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Impact of Airstacking and Digital Pressure Feedback on Pulmonary Function in Restrictive Lung Disease: A Stratified Randomized Controlled Trial by Han Eol Cho, Won Ah Choi, Seul Lee, Seong-Woong Kang

“…Pulmonary function parameters, including forced vital capacity expressed as a percentage of the predicted normal value (FVC%), MIC, and assisted peak cough flow (aPCF), were measured at baseline, 3, 6, and 12 months. …”
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Effects of Different Stocking Densities on Snail <i>Bellamya purificata</i> Foot Muscle Nutritional Quality and Metabolic Function by Yingyue Lou, Rui Jia, Bing Li, Linjun Zhou, Jian Zhu, Yiran Hou

“…To analyze the effect of various stocking densities on the muscle nutritional quality and metabolic functions of <i>B. purificata</i>. The transcriptome and metabolome were analyzed and set up three different density groups—low (LD, 234.38 g/m²), medium (MD, 468.75 g/m²), and high (HD, 937.5 g/m²). …”
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POSSIBILITIES OF PHARMACOLOGICAL CORRECTION OF STRUCTURAL AND FUNCTIONAL ALTERATIONS OF MICROCIRCULATION IN TERMS OF ENDOTHELIAL DYSFUNCTION IN COMORBID PATIENTS SUFFERED STROKE EV... by I. A. Zolotovskaya, I. L. Davydkin

“…Aim of the study – reveal clinical efficacy of naftidrofuryl in the aspect of correcting structural and functional changes of microcirculation (MC) in relation to the influence of the endothelial dysfunction (ED) parameters in comorbid patients suffered stroke event.Materials and methods. …”
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The impact of combined thymol and rosmarinic acid on the intestinal microbiota and barrier function of the piglets challenged by Escherichia coli K88 by Runlin Li, Xuedong Ding, Mingkang Lei, Panpan Li, Ilias Giannenas, Jing Wang, Weiyun Zhu

“…The effects of Thy and Ros-A separately or in combination (Thy × Ros-A) on the intestinal function and health of piglets challenged with Escherichia coli K88 (E. coli K88) were investigated. …”
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Comparative transcriptomics of two petal variants reveals key functional genes underlying petal shape development in lotus (Nelumbo) by Jiaxin He, Jiaxin He, Yini Ma, Qingqing Liu, Rui Zhang, Guohong Huang, Dasheng Zhang, Fengluan Liu, Caixia Yang

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Platelet-derived extracellular vesicles induced through different activation pathways drive melanoma progression by functional and transcriptional changes by Zeynep Tavukcuoglu, Umar Butt, Alessandra V. S. Faria, Johannes Oesterreicher, Wolfgang Holnthoner, Saara Laitinen, Mari Palviainen, Pia R-M Siljander

“…This allowed us to investigate the differential capacity of PEVs to alter cancer hallmark functions such as proliferation, invasion, and pro-angiogenic potential using melanoma as a model. …”
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Comprehensive analysis based on the ubiquitination- and deubiquitylation-related genes reveals the function of NEURL3 in esophageal squamous cell carcinoma by Yi-Wei Lin, Yi-Wei Lin, Hui-Er Li, Hui-Er Li, Chao-Qun Hong, Zi-Ang Chen, Zi-Ang Chen, Shu-Ping Liu, Shu-Ping Liu, Yi-Wei Xu, Yi-Wei Xu, Fang-Cai Wu, Yu-Hui Peng, Yu-Hui Peng

“…Differences in terms of biological function, immune status, and drug sensitivity were evaluated between high- and low-risk groups. …”
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Chasing Biodiversity Off the Scientific and Conservation Tracks by Donald S. Maier

“…Identification of conservation with biodiversity conservation owes extensively to the idea that warrant for biodiversity's conservation is anchored in the empirical thesis that biodiversity causally determines ecosystem functioning, and thereby, somehow, important ecosystem services. …”
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