Autism spectrum disorder related phenotypes in a mouse model lacking the neuronal actin binding protein profilin 2 by Walter Witke, Marina Di Domenico, Laura Maggi, Alessia Di Nardo, Valentin Stein, Pietro Pilo Boyl

“…IntroductionProfilin 2 (PFN2) is an actin binding protein highly expressed in the brain that participates in actin dynamics. …”
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3D IntelliGenes: AI/ML application using multi-omics data for biomarker discovery and disease prediction with multi-dimensional visualization by Rishabh Narayanan, Elizabeth Peker, William DeGroat, Dinesh Mendhe, Saman Zeeshan, Zeeshan Ahmed

“…Results The overall functionality of 3D IntelliGenes is divided into two modules, data clustering and feature plotting. …”
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Correlation between Glycemic Control in Type 2 Diabetes Mellitus Patients with Natural Killer Cell Activity by Dian Ristanti, Gatot Soegiarto, Hermina Novida

“…Natural killer (NK) cell functions were rarely studied in T2DM. This study aimed to evaluate NK cell activity and determine its correlation with glycemic control in T2DM patients. …”
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Non-redundant roles of the CCR1 and CCR2 chemokine axes in monocyte recruitment during lung metastasis by Alessia G. Liner, Merel van Gogh, Marko Roblek, Matthias Heikenwalder, Lubor Borsig

“…This data defines the non-redundant functions of the Ccr1- and Ccr2-chemokine axes in monocyte recruitment and macrophage presence during lung metastasis. …”
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The role of scavenger receptor B1 in infection with Mycobacterium tuberculosis in a murine model. by Georgia Schäfer, Reto Guler, Graeme Murray, Frank Brombacher, Gordon D Brown

“…Like many other receptors for these pathogens, the loss of SR-B1 can be functionally compensated for under normal conditions.…”
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Features of tactics of inspection of accident sites in the investigation of illegal interference in the activities of energy facilities using unmanned vehicles by S. L. Kislenko, A. B. Smushkin

“…In addition, it is impossible to ignore the inter-level connections expressed in the specifics of the organization of interaction between law enforcement agencies with specialists of energy companies and other knowledgeable persons during investigative inspections.…”
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The Effect of Probiotics on the Response to Vaccination in Older Adults: A Systematic Review of Randomised Controlled Trials by Hediye Arioz Tunc, Philip Calder

“…Background: Ageing comes with alterations in many body functions, including the deterioration of the immune system, referred to as immunosenescence. …”
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Cis,cis-muconic acid production from lignin related molecules byAcinetobacter baylyi ADP1 by Changshuo Liu, Vilja Juvonen, Ella Meriläinen, Elena Efimova, Jin Luo, Milla Salmela, Suvi Santala, Ville Santala

“…To redirect these LRM toward ccMA production, the two branches must be functionally integrated. This is usually achieved by introducing a non-native enzymatic activity, specifically protocatechuate decarboxylase (PCADC), which catalyzes the conversion of protocatechuate to catechol. …”
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The adenoviral E4orf4 protein: A multifunctional protein serving as a guide for treating cancer, a multifactorial disease by Amir Basis, Rakefet Sharf, Tamar Kleinberger

“…The adenovirus E4orf4 protein, which disrupts several host regulatory pathways to facilitate viral infection, also functions as a potent anti-cancer agent when expressed independently. …”
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The right to the freedom of peaceful assembly under the rule of law: convergence and mutual implementation by M. A. Sambor

“…Reflecting on the issues of positive and negative interference of the State, the State apparatus, State bodies, local self-government bodies in public relations regarding the use, exercise and restoration of the right to freedom of peaceful assembly, the question arises as to the impact of the fundamental principles of building and functioning of power in a democratic state on their organizational and practical activities. …”
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Genetic overlap between schizophrenia and constipation: insights from a genome-wide association study in a European population by Qinghua Luo, Mingwei An, Yunxiang Wu, Jiawen Wang, Yuanting Mao, Leichang Zhang, Chen Wang

“…Further investigation into the functions of these genes could provide valuable insights. …”
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THE INFLUENCE OF THE LEVEL OF SOCIAL INTELLIGENCE DEVELOPMENT ON THE CHOICE OF RESPONSE STRATEGY IN CONFLICT SITUATIONS by Olena V. Karapetrova

“…The concept of social intelligence, its structure and functions, modern approaches to the problem of social intelligence development in young people are considered. …”
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Antibiotics and Antimicrobial Resistance Genes in a Gut Microbiota as a Reservoir—A Review by Bismark Dabuo, Abudu Abubakari, Frances Ellen Sankah, Hannah Aryeley Aryee

“…This emphasizes how important it is that we understand how the human body functions on the inside as well as the outside sources of infections. …”
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Effect of tobacco control policies on the Swedish smoking quitline using intervention time-series analysis by Alessio Crippa, Anna-Karin Danielsson, Xingwu Zhou, Nicola Orsini

“…Statistical inference on calling rates and rate ratios was obtained using intervention time-series models (Poisson regression and transfer functions).Participants A total of 179 851 phone calls to the SNTQ.Interventions Recent application of the 2014/40/ European Union (EU) Tobacco Products Directive in 2016. …”
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A novel HVEM-Fc recombinant protein for lung cancer immunotherapy by Yuanshan Yao, Bin Li, Jing Wang, Chunji Chen, Wen Gao, Chunguang Li

“…Abstract Background The ubiquitously expressed transmembrane protein, Herpesvirus Entry Mediator (HVEM), functions as a molecular switch, capable of both activating and inhibiting the immune response depending on its interacting ligands. …”
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The co-receptor Tetraspanin12 directly captures Norrin to promote ligand-specific β-catenin signaling by Elise S Bruguera, Jacob P Mahoney, William I Weis

“…Our findings suggest that Tspan12 does not allosterically enhance Fzd4 binding to Norrin or Dvl, but instead functions to directly capture Norrin upstream of signaling.…”
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Identification of cell specific biomarkers for intellectual disability via single cell RNA sequencing and transcriptomic bioinformatics approaches by Kh Mujahidul Islam, Md Habibur Rahman, Md. Arju Hossain, Mahfuj Khan, Md. Mizanur Rahman, Prosenjit Saha Apu, Md Imran Hasan, Siddique Akber Ansari, Mahammad Humayoo

“…Abstract Limitations in cognitive functioning and adaptive behavior are hallmarks of Intellectual Disability (ID), a neurodevelopmental disease. …”
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Effects of Metallicity on Graphite, TiC, and SiC Condensation in Carbon Stars by Gabrielle M. Adams, Katharina Lodders

“…Graphite, however, can condense in a cooling circumstellar envelope before TiC, between TiC and SiC, or after SiC, depending on the carbon-bearing gas chemistry, which is dependent on metallicity and total pressure. Analytical expressions for the graphite, TiC, and SiC condensation temperatures as functions of metallicity and total pressure are presented. …”
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Expanded Bioclimatic Variables Extracted from Monthly Climate Predictions under the SSP Climate Scenarios over South Korea by Jieun Oh, Ah Reum Han, Yeong-cheol Kim, Seungbum Hong

“…These shifts lead to transformations in ecosystem structure, components, and functions. Exploring the connections between species and climate change is essential for developing adaptation strategies. …”
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Illegal use of physical force and special means against prisoners: criminological characteristics and preventive measures by Alexander M. Smirnov

“…Measures taken to prevent the occurrence of negative phenomena in domestic politics can have a positive impact on improving the functioning of the penal correction system, which is in line with legal regulations of a national and international nature.…”
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