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28541
Exploration of the diagnostic and prognostic roles of decreased autoantibodies in lung cancer
Published 2025-01-01“…IntroductionTumor-associated antigens (TAA) are proteins expressed during the growth and development of tumor cells, and TAA autoantibodies (TAAbs) can be detected in the serum of lung cancer patients, which can be utilized in the early screening of lung cancer. …”
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28542
Discovery of Novel Thanatin-like Antimicrobial Peptides from Bean Bug <i>Riptortus pedestris</i>
Published 2024-11-01“…<b>Conclusions:</b> This study extends the knowledge of the structure and functions of insect host defense AMPs. Each of the novel β-hairpin peptides has a potential to be a template for the development of selective antibiotic drugs.…”
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28543
Facial Emotion Images Recognition Based On Binarized Genetic Algorithm-Random Forest
Published 2024-02-01“…In addition, the Binarized Genetic Algorithm (BGA) is utilized as a features selection in order to select the most effective features of HOG. Random Forest (RF) functions as a classifier to categories facial emotions in people according to the image samples. …”
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28544
SLC25A35 enhances fatty acid oxidation and mitochondrial biogenesis to promote the carcinogenesis and progression of hepatocellular carcinoma by upregulating PGC-1α
Published 2025-03-01“…Functionally, SLC25A35 promoted the proliferation and metastasis of HCC cells both in vitro and in vivo, as well as the carcinogenesis in a DEN-induced HCC mice model. …”
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28545
A novel GJA3 mutation causing autosomal dominant congenital perinuclear cataracts
Published 2025-04-01“…Connexin localization and gap junction formation were assessed by fluorescence microscopy, and hemichannel functions were analyzed by dye uptake assay. Results Gene sequencing showed one base pair substitution at position 671 of the GJA3 gene’s coding region (c.671A > G), leading to the conversion of the 224th amino acid of the Connexin 46 protein (Cx46), expressed by the GJA3 gene, from histidine to arginine (p.H224R). …”
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28546
Parabacteroides goldsteinii mitigates the lipopolysaccharide-induced inflammatory response in IPEC-J2 cells
Published 2025-05-01“…GO analysis was used to annotate the functions of the DEGs, and the results showed that biological regulation, cellular anatomical entity, and binding were dominant. …”
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28547
Metabolomics and lipidomics of plasma biomarkers for tuberculosis diagnostics using UHPLC-HRMS
Published 2025-06-01“…However, the characteristics of the circulating metabolites and their functions after Mycobacterium tuberculosis infection have not been fully elucidated. …”
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28548
Comparative Proteomic Insights into the Immune Response of <i>Conogethes punctiferalis</i> Challenged with <i>Beauveria bassiana</i>
Published 2025-06-01“…On the basis of proteomic analysis, 4195 quantifiable proteins were identified from a total of 29,155 peptides. The functions of the identified proteins were annotated in four databases (GO, COG, KEGG, and IPR). …”
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28549
The Identification of a Glucuronyltransferase-Related Gene, <i>GlcAT-S,</i> with Putative Mucus Protection and Anti-Inflammatory Effects from Gut-Damaged <i>Drosophila</i> by Dextr...
Published 2025-05-01“…The intestinal epithelium, which is protected by mucosal surfaces composed of mucins and other glycoproteins, functions as a selective barrier that absorbs nutrients while preventing the translocation of harmful substances. …”
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28550
Hierarchical Gaussian processes for characterizing gait variability in multiple sclerosis
Published 2025-01-01“…Rather than summarizing features, this approach models the entire gait cycle functionally, including its variation. A Hierarchical Variational Sparse Heteroscedastic Gaussian Process was used to model the shank angular velocity across 28 MS and 28 healthy individuals. …”
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28551
MvfR Shapes <i>Pseudomonas aeruginosa</i> Interactions in Polymicrobial Contexts: Implications for Targeted Quorum-Sensing Inhibition
Published 2025-05-01“…Using a collection of <i>P. aeruginosa</i> QS mutants of the three major systems, LasR/LasI, MvfR/PqsABCDE, and RhlR/RhlI, and mutants of several QS-regulated functions, we reveal that MvfR and, to a lesser extent, LasR and RhlR, control competition between <i>P. aeruginosa</i> and other microbes, possibly through their positive impact on pyoverdine, pyochelin, and phenazine genes. …”
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28552
Bovine milk consumption affects the transcriptome of porcine adipose stem cells: Do exosomes play any role?
Published 2024-01-01“…Over 500 genes were differentially expressed (DEG) in ASC isolated from M vs. C pigs. …”
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28553
Standardized mean age at death (MADstd): Exploring its potentials as a measure of human longevity
Published 2024-04-01“…OBJECTIVE: We want to highlight the common structure of the three measures by expressing them as weighted averages with different weighting functions. …”
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28554
The role of root dynamics on the climate sensitivity of ecohydrological processes of over- and understory in a semi-arid groundwater-dependent ecosystem
Published 2024-12-01“…Plant roots connect belowground moisture with aboveground vegetation functionalities, making root plasticity critical for drought resilience. …”
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28555
A Fractional Time–Space Stochastic Advection–Diffusion Equation for Modeling Atmospheric Moisture Transport at Ocean–Atmosphere Interfaces
Published 2025-03-01“…An efficient numerical solution methodology is derived utilizing complementary Fourier and Laplace transforms, which elegantly converts spatial fractional operators into algebraic expressions and yields closed-form solutions via Mittag–Leffler functions. …”
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28556
Gastrin‐Releasing Peptide Facilitates Cholinergically Mediated Contractions of the Mouse Gastric Fundus
Published 2025-08-01“…When exogenously administered, they contract stomach muscle in several species, but their ability to modulate enteric nerve functions has rarely been studied. We investigated the effects of GRP on cholinergic‐mediated contractions of the stomach, after first characterizing the contractile effects of GRP, NMB, and bombesin (BB). …”
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28557
Exosomal miR-452-5p Induce M2 Macrophage Polarization to Accelerate Hepatocellular Carcinoma Progression by Targeting TIMP3
Published 2022-01-01“…Here, we further explored how miR-452-5p functions in HCC. Methods. MiR-452-5p expressions in HCC cells was examined by in situ hybridization. …”
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28558
Incidence of complications after laparoscopic and hysteroscopic surgeries for uterine myomas
Published 2019-07-01“…All patients were examined for their history of gynecological and concomitant non-gynecological diseases, past surgeries, and the menstrual, sexual and reproductive functions. The patients underwent clinical blood analysis, urinalysis, electrocardiography and chest X-ray test, blood group and rhesus factor determination, hemostasis assay, blood analysis for RV, HIV and tumor markers, as well as transabdominal and transvaginal ultrasound using SSD-1200 and SSD-2000 devices (Aloka Ltd, Japan). …”
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28559
Assessing the usability and performance of digital healthcare systems in Nigerian teaching hospitals: Challenges and future directions
Published 2025-05-01“…Result Findings showed that 79.4% of clinicians identified feature gaps and expressed the need for additional functionalities. …”
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28560
Ethical Aspects of the Influence of Neural Networks on the Lives of Students in the Context of a Sociological Approach (using the Example of Students of the IT Department of ETU)
Published 2025-06-01“…The modern understanding of artificial intelligence as a complex of technologies capable of imitating human cognitive functions, including selflearning, is considered. The concepts of А. …”
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