Aplicação da lógica fuzzy na análise sensorial de pão de forma enriquecido Fuzzy logic application in sensory analysis of enriched loaf by Mônica T. Cavalcanti, Flávio L. H. da Silva, José H. F. Cavalcanti, Eliane R. Florentino, Isanna M. Florêncio, Ricardo T. Moreira

“…In this logic every variable has a set of functions, represented in an X universe, which generally expresses a linguistic variables group of the system. …”
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A plug and play fuzzy mask extraction module for single image deraining by Mingdi Hu, Yao Song, Songxin Zhang, Zejian Xie, Bingyi Jing

“…Specifically, fuzzy mask maps of the rain data-set are obtained by optimizing the convex combination of several grouping functions; Based on these fuzzy mask maps as ground truth, we develop a deep learning architecture that learns the fuzzy rain map; We then fix the model to obtain a unified network model as a plug and play fuzzy mask extraction module for Single Image Deraining; When we embed a plug and play fuzzy mask extraction module into a deraining deep neural network architecture, it will improve performance due to fusion with the fine guided information of the fuzzy rain mask map. …”
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Rapid Pain Assessment Tool avatar self-pain report: a new objective method for adequate pain diagnosis? Pilot study by A. Popelnukha, D.V. Dmytriiev

“…Key findings include: а 30 % reduction in analgesic dosage required for pain relief; 85 % of participants expressed high satisfaction with the avatar-based assessment; 72 % of patients demonstrated clinical improvements with better pain control and functionality. …”
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Cache-Enabled Software Defined Heterogeneous Networks for Green and Flexible 5G Networks by Jiaxin Zhang, Xing Zhang, Wenbo Wang

“…., the coverage probability, throughput, and energy efficiency (EE), are derived as closed-form expressions or the functions of the signal-to-interference-plus-noise ratio threshold, path loss exponent, transmission power and density of macro and SCs, cache ability, file popularity, and backhaul capacity. …”
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Unknown Words (Agnonyms) in Russian Village Prose and Their Translations into English (Linguocultural Aspect) by Zhang Xiao

“…The purpose of the article is to consider the ways of rendering Russian unknown words (agnonyms) in Russian literary texts about the village in translation into English and to analyze the lost functions and characteristics of Russian unknown words in English translation from the point of view of linguocultural differences between Russian and English. …”
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Evaluation of Coenzyme Q10 Redox Status as a Biomarker of Oxidative Stress by O. A. Goroshko, L. M. Krasnykh, V. G. Kukes, V. I. Zozina

“…The article examines the role of ubiquinone as a redox molecule whose functions consist in electron transport in the mitochondrial respiratory chain and regeneration of endogenous antioxidants. …”
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The Identification Distinct Antiviral Factors Regulated Influenza Pandemic H1N1 Infection by Baoxin Wang, Hao Zheng, Xia Dong, Wenhua Zhang, Junjing Wu, Hongbo Chen, Jing Zhang, Ao Zhou

“…In addition, we found that different H1N1pdm strains induced similarly innate immune responses and the identified DEGs during H1N1pdms infection were functionally concentrated in defence response to virus, cytokine-mediated signalling pathway, regulation of innate immune response, and response to interferon. …”
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The Relationship between Toll-like Receptors and Helicobacter pylori-Related Gastropathies: Still a Controversial Topic by Lorena Elena Meliț, Cristina Oana Mărginean, Cristian Dan Mărginean, Maria Oana Mărginean

“…Further studies are required in order to develop preventive and therapeutic strategies against H. pylori infections based on the functions of TLRs.…”
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A versatile silica nanoparticle platform for induction of T cell responses – applied for therapeutic vaccination against HPV16 E6/E7-positive tumors in MHC-humanized mice by Sebastian Kruse, Lia T. Fricke, Samantha Zottnick, Ann-Katrin Schlosser, Agnieszka K. Grabowska, Eva Feidt, Philipp Uhl, Ellen Junglas, Jonas D. Förster, Josephine Blersch, Philip Denner, Manina Günter, Stella E. Autenrieth, Eugenio Fava, Walter Mier, Armin Kübelbeck, Angelika B. Riemer

“…We show that surface-functionalized SiNPs are non-cytotoxic and quickly taken up by APCs. …”
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sPLA2-IIA modifies progranulin deficiency phenotypes in mouse models by Cha Yang, Huan Du, Gwang Bin Lee, Masaaki Uematsu, Weiguo He, Etienne Doré, Weizhi Yu, Ethan J. Sanford, Marcus B. Smolka, Eric Boilard, Jeremy M. Baskin, Ling Hao, Fenghua Hu

“…Mouse models have been developed to study PGRN functions. However, PGRN deficiency in the commonly used C57BL/6 mouse strain background leads to very mild phenotypes, and pathways regulating PGRN deficiency phenotypes remain to be elucidated. …”
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Urease in acetogenic Lachnospiraceae drives urea carbon salvage in SCFA pools by Isaac J. Firth, Marissa A.R. Sim, Bradley G. Fitzgerald, Ailish E. Moore, Christian R. Pittao, Connor Gianetto-Hill, Samantha Hess, Autumn R. Sweeney, Emma Allen-Vercoe, Matthew T. Sorbara

“…In agreement, the combination of urease and acetogenesis functions is rare in gut taxa. We find that Lachnospiraceae urease and acetogenesis genes can be co-expressed in healthy individuals and colonization of mice with a ureolytic Blautia reduces urea availability in colon contents demonstrating Blautia urease activity in vivo. …”
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Contribution of Connexin Hemichannels to the Pathogenesis of Acute Lung Injury by Shuaiwei Wang, Yafang Sun, Yu Bai, Nannan Zhou, Na Chen, Edmund J. Miller, Yijie Zhang, Wei Li

“…Connexin (Cx) family members form hemichannels (HCs) and gap junctions (GJs). Biological functions of Cx HCs have not been adequately characterized due to the inability to selectively target HCs or GJs. …”
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Exploratory actor mapping of social interactions within tick risk surveillance networks in France by Iyonna Zortman, Laurence Vial, Thomas Pollet, Aurélie Binot

“…We conducted 13 semi-structured interviews with French tick risk surveillance actors to characterize how the national surveillance system functions. Qualitative descriptive analysis was conducted on interview transcripts to create actor maps and identify the barriers and levers for actor interactions. …”
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Constructed transferrin receptor-targeted liposome for the delivery of fluvoxamine to improve prognosis in a traumatic brain injury mouse model by Liang Mi, Jiangyuan Yuan, Yuxing Jiang, Yuqian Hu, Chuanxiang Lv, Yongqiang Xu, Mingqi Liu, Tao Liu, Xuanhui Liu, Jinhao Huang, Rongcai Jiang, Wei Quan

“…Furthermore, TPL-Flv accomplished remarkable improvement of motor and cognitive functions. These findings demonstrate that TPL-Flv can effectively cross BBB and achieve drug delivery to cerebral tissue, validating its potential to improve therapeutic outcomes for TBI.…”
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Co-Cultivation with Azolla Affects the Metabolome of Whole Rice Plant Beyond Canonical Inorganic Nitrogen Fertilization by Elena Consorti, Alma Costarelli, Sara Cannavò, Martina Cerri, Maria Cristina Valeri, Lara Reale, Antonietta Saccomanno, Chiara Paleni, Veronica Gregis, Martin M. Kater, Federico Brilli, Francesco Paolocci, Andrea Ghirardo

“…Understanding the molecular mechanisms by which Azolla functions as a biostimulant in rice co-culture will facilitate the development of more sustainable and environmentally friendly techniques to increase yields.…”
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Calcitriol Inhibits the Proliferation of Triple-Negative Breast Cancer Cells through a Mechanism Involving the Proinflammatory Cytokines IL-1β and TNF-α by Isela Martínez-Reza, Lorenza Díaz, David Barrera, Mariana Segovia-Mendoza, Sigifredo Pedraza-Sánchez, Giovanny Soca-Chafre, Fernando Larrea, Rocío García-Becerra

“…In summary, this study demonstrated that calcitriol exerted its antiproliferative effects in part by inducing the synthesis of IL-1β and TNF-α through IL-1R1 and TNFR1, respectively, in TNBC cells, highlighting immunomodulatory and antiproliferative functions of calcitriol in TNBC tumors.…”
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Friend or foe? The role of SIRT6 on macrophage polarized to M2 subtype in acute kidney injury to chronic kidney disease by Xiaoqin Gao, Xingwei Liu, Zhaodi Han, Hui Liao, Rongshan Li

“…M1 and M2 macrophages—the two main types of macrophages—have distinct functions at various stages. M1 macrophages induce kidney damage by secreting pro-inflammatory cytokines immediately after injury, whereas M2 macrophages subsequently facilitate kidney tissue repair. …”
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Diverging effects of tumor necrosis factor inhibitors and conventional synthetic disease-modifying antirheumatic drugs on immunosenescence and inflammageing in rheumatoid arthritis... by Tobias Schwarz, Giovanni Almanzar, Sebastian Völkl, Martin Feuchtenberger, Johannes Leierer, Christian Schmidt, Frank Deininger, Hans-Peter Tony, Marc Schmalzing, Martina Prelog

“…We investigated parameters of immunosenescence in RA patients treated with conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) only compared to patients treated additionally or exclusively with a tumor necrosis factor inhibitor (TNFi) and age-matched healthy controls to investigate the effect of RA treatment on age-associated T cell phenotypes and functions. Results The csDMARD-only treated patients, compared to the TNFi-treated patients and healthy controls, displayed an enhanced age-dependent decline in CD31+ recent thymic emigrants (RTE) and Interleukin-7 (IL-7)-receptor α-chain (CD127)-expressing CD4+ T cells participating in IL-7-associated homeostatic proliferation, a diminished proliferation of RTE and CD127+ T cells, as well as reduced T cell receptor excision circle (TREC) counts. …”
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Patients’ experiences with GLP1-RAs – a systematic review by Christoffer Kraul Ibsen, Marius Brostrøm Kousgaard, Sofie Olsen, Ann-Kathrin Lindahl Christiansen, Catharina Thiel Sandholdt, Rasmus Rørth, Gritt Overbeck

“…The analysis identified five key themes: (1) Patients are willing to accept adverse events, like gastrointestinal disorders, for successful weight loss, (2) Patients experience improved physical functioning, well-being, and active daily living as a result of weight loss, (3) Patients express diverse opinions and skills regarding the medication’s usability, (4) Patients believe that the medication improves their ability to manage sweet cravings, (5) Gender seems to affect patients’ experiences with the medication, with females reporting more benefits than males.Conclusion Despite a huge demand and usage of GLP1-RAs, qualitative research on patients’ experiences is scarce. …”
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Antitumor effects of natural killer cells derived from gene-engineered human-induced pluripotent stem cells on hepatocellular carcinoma by Mayuna Nakamura, Yuka Tanaka, Keishi Hakoda, Masahiro Ohira, Tsuyoshi Kobayashi, Kenji Kurachi, Kouichi Tamura, Hideki Ohdan

“…Our data suggest that eNK cells, whose functions have been enhanced by genetic engineering, have the potential to improve HCC treatment.…”
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