Choline Alphoscerat (Gliatilin) in the pathogenetic therapy of Alzheimer’s disease by D. V. Zaharov, V. A. Mihailov, Y. V. Kotsiubinskaya

“…Glitatylin (choline alfoscerate) has a stimulating effect on cognitive functions and improves memory and attention, leads to the correction of psycho-emotional disorders. …”
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Visible Exocytosis of the Non-Photic Signal Neuropeptide Y to the Suprachiasmatic Nucleus in Fasted Transgenic Mice Throughout Their Circadian Rhythms by Kazuo Nakazawa, Minako Matsuo, Kazuki Nakao, Shigenori Nonaka, Rika Numano

“…The suprachiasmatic nucleus (SCN) occupies the top position of the hierarchy in the mammalian circadian system and functions as a photic-dependent oscillator, while the food-entrainable circadian oscillator (FEO) entrains the clocks of the digestive peripheral tissues and behaviors according to feeding timing. …”
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Engineering hydrophobicity and manufacturability for optimized biparatopic antibody–drug conjugates targeting c-MET by Andreas Evers, Simon Krah, Deniz Demir, Ramona Gaa, Desislava Elter, Christian Schroeter, Stefan Zielonka, Nicolas Rasche, Julia Dotterweich, Christine Knuehl, Achim Doerner

“…Optimized variants showed high stability, strongly reduced hydrophobicity, retained affinities supporting the desired functionality and enhanced producibility. The resulting biparatopic anti-c-MET ADCs were comparably active on c-MET expressing tumor cell lines as REGN5093 exatecan DAR6 ADC. …”
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Role of galectin-9 in the development of gestational diabetes mellitus by Haya Hamed Hassan Albuayjan, Mayu Watanabe, Ryosuke Sugawara, Eri Katsuyama, Koki Mise, Yukiko Oi, Ayaka Kanno, BoXuan Yang, Toshihisa Tahara, Ichiro Nojima, Atsuko Nakatsuka, Jun Eguchi, Jota Maki, Eriko Eto, Kei Hayata, Hisashi Masuyama, Jun Wada

“…The elevation of plasma Gal-9 may be a biomarker for prediction of maternal glucose intolerance and fetal macrosomia in pregnant women with GDM and Gal-9 functions as a compensation factor for GDM by inducing apoptosis in Tim-3 + trNK cells.…”
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Profiling the Secretome of Glioblastoma Cells Under Histone Deacetylase Inhibition Using Mass Spectrometry by Aline Menezes, Yara Martins, Fábio Nogueira, Denise De Abreu Pereira, Katia Carneiro

“…A label-free, mass spectrometry–based quantitative proteomics has been developed to identify and characterize proteins that are differentially expressed in GBM to gain a better understanding of the interactions and functions that lead to the pathological state focusing on the extracellular matrix (ECM). …”
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RENIN-ANGIOTENSIN SYSTEM IN REGULATION OF HEMATOPOIESIS by M. L. Kanaeva, I. V. Galtseva, I. M. Nakastoev, Y. B. Balzhanova, E. O. Gribanova, E. N. Parovichnikova, V. G. Savchenko

“…Local RAS is also one of the most important components in the tumor microenvironment, affecting tumor growth and metastasis by autocrine and paracrine pathways, modulating numerous carcinogenic events such as angiogenesis, apoptosis, cell proliferation, immune responses, and extracellular matrix formation.The purpose of this review is to describe the known functions of local RAS in the hematopoiesis regulation. …”
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Designs of NKG2D-based immunotherapeutics for cancer by Jianfeng Han, Youwei Wang, Godfrey Chi-Fung Chan, Godfrey Chi-Fung Chan, Wing Keung Chan

“…Despite being genomically conserved between human and mouse, NKG2D transcripts have splice variants that can differentiate the two. hNKG2D or mNKG2D (both long and short transcripts) interacts with DAP10 only in human but DAP10/12 in mouse, switching on different effector functions such as IFN-γ production and cytotoxicity. …”
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The crucial role of SPP1 in osteoporosis, osteoarthritis, and cancer by Yaru Qu, Shuixian Li, Huiyuan Luo, Junnan Li, Tong Wang, Xiuzhen Han

“…This review integrates the molecular structural characteristics of SPP1, including isoform variants and post-translational modifications, with its pathophysiological functions. It highlights the regulatory roles of SPP1 in these diseases: maintaining the dynamic balance between bone resorption and formation in osteoporosis, promoting cartilage degeneration and inflammation in osteoarthritis, and driving tumor progression in cancer through the activation of pathways such as PI3K/AKT/mTOR. …”
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Adipose Tissue Macrophages of the Human Fetus by Ádám Radványi, Katalin Gyurina, Emese Rácz, Ilona Kovács, Gábor Méhes, Tamás Röszer

“…Despite being relevant regulators of adipose tissue development and functioning, it is unknown whether ATMs are present in the fetal adipose tissue, therefore it is elusive whether they may affect the prenatal establishment of fat depots. …”
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Loss of Ercc1 Results in a Time- and Dose-Dependent Reduction of Proliferating Early Hematopoietic Progenitors by Judith H. E. Verhagen-Oldenampsen, Jurgen R. Haanstra, Paulina M. H. van Strien, Marijke Valkhof, Ivo P. Touw, Marieke von Lindern

“…The endonuclease complex Ercc1/Xpf is involved in interstrand crosslink repair and functions downstream of the Fanconi pathway. Loss of Ercc1 causes hematopoietic defects similar to those seen in Fanconi Anemia. …”
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Communication System Using Natural Language for Robotic Laparoscope Guidance by Pan Yan, Bernhard Lukas, Fan Cheng, Beckendorf Lukas, Wilhelm Dirk, Feußner Hubertus, Groh Georg

“…Also, our proposed conversational functions enable the finetuned large language models to understand the current natural language command given previous command history. …”
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Family Medicine for internally displaced persons in Mali: A training of trainers approach by Drissa M. Sidibé, Ann Isabelle Grégoire, Véronique Lisée, Pierre Rodrigue Traoré, Inhissa B. Bengaly, Aboubakary Konaté, Ibrahim H. Sidibé, Sabina Abou Malham, David-Martin Milot, Gabriel Blouin-Genest

“…Mali is currently experiencing a polycrisis, characterised by the interplay of growing socio-political insecurity, massive population displacements and recurrent tensions in the functioning of the health system and the provision of care. …”
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Loneliness is related to facial emotion perception in people with HIV by Moka Yoo-Jeong, Rebecca E. Easter, Jennifer M. Coughlin, Raha M. Dastgheyb, Scott A. Langenecker, Gabriela Molestina, Juhi Patel, Skylar Rucci, Eran F. Shorer, Isabelle Thompson, Alejandra Woolsey, Tracey E. Wilson, Leah H. Rubin

“…Findings suggest that emotional and social loneliness are related to different aspects of FEP, underscoring the need for interventions targeting loneliness subtypes to improve FEP deficits and social-emotional functioning in PWH.…”
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Positive Politeness Strategies on Billboards for Legislative Candidates in Banyumas Regency in 2024 by Chusni Hadiati, Ely Triasih Rahayu, Sri Nani Hari Yanti, Kuntarto Kuntarto

“…This study aims to fill the gap in previous research that has not examined commissive speech acts in the context of campaign billboards, emphasizing a pragmatic approach to understanding how language functions in political communication. All the data were in the form of text from 210 billboards photographed along Banyumas protocol roads, and 30 of them contained positive politeness. …”
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The solute carrier family 11 transporters: a bridge between iron homeostasis and tumor biology by Ruchira Banerjee, Bintee Bintee, Mukesh Kumar Manickasamy, Shristy Jha, Mohammed S. Alqahtani, Mohamed Abbas, Arul Goel, Gautam Sethi, Zhaowu Ma, Ajaikumar B. Kunnumakkara

“…In this review, we provide an overview of the physiological functions of SLC11 transporters in iron metabolism and their pathological roles in cancer biology. …”
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CURRENT STATE AND PROSPECTS OF COMPUTER TERMINOLOGY ONLINE LEXICOGRAPHY by Iryna B. Mentynska

“…During the research the most popular online dictionaries that record IT terms have been selected; the parameters of such online dictionaries are characterized; their practical functions for application in the IT sphere are highlighted; the main trends affecting the further study of the features of the lexicography process are identified and outlined. …”
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Methods for Applying Matrices when Creating Models of Group Pursuit by A. A. Dubanov

“…The listed processes were illustrated by functions in the given coordinate systems and animation. …”
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Glucocorticoid Insensitivity: Is It a Question of Time and Place? by Christopher Lambers, Michael Roth

“…The GR only functions when it forms a complex with other intracellular proteins that regulate ligand binding, cytosol-to-nuclear transport, and nuclear and cytosolic action. …”
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Once again on spasticity in neurology (literature review) by M. A. Barabanova, O. V. Stoyanova, T. A. Petropavlovskaya, D. O. Kardailskaya

“…At the same time it limits physical activity in a patient by itself, but the expressed spasticity considerably aggravates motive violations, even more reducing functionality in a patient. …”
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Perceptions and attitudes of black men in a rural district of South Africa towards depression and its treatment by Hlabje C. Masemola, Saiendhra V. Moodley, Joyce Shirinde

“…Background: Depression is a major contributor to the overall global burden of disease, impacting social life, family life and occupational functioning if left untreated. Despite its high prevalence and morbidity, the evidence suggests that men are hesitant to seek help, with a large percentage remaining undiagnosed. …”
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