Multiple-omics analysis of aggrephagy-related cellular patterns and development of an aggrephagy-related signature for hepatocellular carcinoma by Jiafen Xie, Xiaoming Wang

“…Further subclustering of malignant hepatocytes using inferCNV revealed eight functionally heterogeneous subpopulations with extensive intercellular crosstalk. …”
Get full text

Cellular reactions of CD3+ CD4+ CD45RO+ T-lymphocytes on dexamethason in in normal patients and in patients with with rheumatoid arthritis in vitro by L. S. Litvinova, N. M. Todosenko, O. G. Khaziakhmatova, I. P. Malinina, K. A. Yurova

“…We assume that the resistance of CD4+CD45RO+CD95+HLA-DR+ T cells in RA patients to the suppressor effect of GC generally leads to the preservation and enhancement of the functionality of autoreactive cells in the pathogenesis of RA.…”
Get full text

Differential GTP-dependent in-vitro polymerization of recombinant Physcomitrella FtsZ proteins by Stella W. L. Milferstaedt, Marie Joest, Lennard L. Bohlender, Sebastian N. W. Hoernstein, Buğra Özdemir, Eva L. Decker, Chris van der Does, Ralf Reski

“…Taken together, our results reveal that Physcomitrella FtsZ1-2 and FtsZ2-1 are functionally different, can synergistically interact in vivo and in vitro, and differ in their properties from FtsZ proteins from bacteria, archaea and vascular plants.…”
Get full text

Turnip mosaic virus infection cleaves MEDIATOR SUBUNIT16 in plants increasing plant susceptibility to the virus and its aphid vector Myzus persicae by Swayamjit Ray, Tyseen Murad, Gabriella D. Arena, Kanza Arshad, Zebulun Arendsee, Venura Herath, Steven A. Whitham, Clare L. Casteel

“…This suggests MED16 functions in the nucleus may be impacted in virus infected plants. …”
Get full text

Comparative Study of PPARγ Targets in Human Extravillous and Villous Cytotrophoblasts by Fulin Liu, Christine Rouault, Mickael Guesnon, Wencan Zhu, Karine Clément, Séverine A. Degrelle, Thierry Fournier

“…Downstream annotation analysis revealed the similarities and differences between RT-EVCTs and RT-VCTs with respect to the biological processes, molecular functions, cellular components, and KEGG pathways affected by the treatment, as well as predicted binding sites for both protein-protein interactions and transcription factor-target gene interactions. …”
Get full text

Experiences of Individually Tailored Internet-Based Cognitive Behavioral Therapy During the COVID-19 Pandemic: Qualitative Interview Study by Victoria Aminoff, Matilda Baltius, Emelie Lundström, Matilda Berg, Gerhard Andersson, Mikael Ludvigsson

“…ConclusionsThe results closely align with those of previous qualitative studies on experiences of ICBT. Participants expressed appreciation of the treatment’s content and format. …”
Get full text

TRPC6-Mediated Zn²⁺ Influx Negatively Regulates Contractile Differentiation of Vascular Smooth Muscle Cells by Chenlin Su, Xinya Mi, Tomoya Ito, Yuri Kato, Akiyuki Nishimura, Ryu Nagata, Yasuo Mori, Motohiro Nishida

“…There were no significant differences in TRPC6-dependent cation currents among all RAoSMCs pretreated with or without TGFβ and/or PPZ2, suggesting that TRPC6 channels are functionally expressed in RAoSMCs regardless of their phenotype. …”
Get full text

ViralLink: An integrated workflow to investigate the effect of SARS-CoV-2 on intracellular signalling and regulatory pathways. by Agatha Treveil, Balazs Bohar, Padhmanand Sudhakar, Lejla Gul, Luca Csabai, Marton Olbei, Martina Poletti, Matthew Madgwick, Tahila Andrighetti, Isabelle Hautefort, Dezso Modos, Tamas Korcsmaros

“…Through a case study of SARS-CoV-2 infected bronchial/tracheal epithelial cells, we evidence the functionality of the workflow and its ability to identify key pathways and proteins in the cellular response to infection. …”
Get full text

Nickel(II) and cadmium(II) uptake by carbon iron composite derived from Pelargonium graveolens by P.M. Thabede, N.D. Shooto

“…The carbon was activated with phosphoric acid and then functionalized with iron oxide using a precipitation method. …”
Get full text

Impact of Family Environment on Mental Well-Being of Adolescent Girls: A Cross-Sectional Survey by Sushil Kumar Maheshwari, Rintu Chaturvedi, Sandhya Gupta

“…The family environment influences adolescence psychological adjustment and problem-solving strategies as well as self-confidence and abilities to set clear goals. The healthy functioning of these interaction patterns enhances the mental well-being of an individual. …”
Get full text

Social support and avoidance mediate positive and negative effects of emotion recognition ability on mental health in medical students by Nils R. Sommer, Valerie Carrard, Céline Bourquin, Alexandre Berney, Katja Schlegel

“…Abstract The ability to recognize others’ feelings from nonverbal expressions, known as emotion recognition ability (ERA), is considered a crucial socio-emotional competence that may enhance both intra- and interpersonal functioning in healthcare professionals. …”
Get full text

Weaker beta desynchronization indicates impaired emotion recognition in schizophrenia by Gábor Csukly, Hajnalka Molnár, Csilla Marosi, Zsuzsanna Fodor, Kinga Farkas

“…Abstract In schizophrenia, deficits in social cognition, such as facial emotion identification, have a significant impact on patient’s daily functioning and quality of life. We analyzed the beta event-related desynchronization (ERD) associated with emotional facial displays to understand better both phase-locked (i.e., neural activity and corresponding EEG response have a fixed latency after the stimulus onset) and non-phase-locked, induced (i.e. the latency of the response is not fixed) electrophysiological correlates of emotion recognition. 128 channels of EEG data from 37 patients with schizophrenia and 40 healthy controls were analyzed. …”
Get full text

ICP0 dismantles microtubule networks in herpes simplex virus-infected cells. by Mingyu Liu, Edward E Schmidt, William P Halford

“…For 25 years, the nuclear functions of ICP0 have been the subject of intense scrutiny. …”
Get full text

AI Response Quality in Public Services: Temperature Settings and Contextual Factors by Domenico Trezza, Giuseppe Luca De Luca Picione, Carmine Sergianni

“…Investigating these “behind-the-scenes” dynamics is essential for fostering the <i>informed governance</i> of AI in public services, and for avoiding the risk of technology functioning as an opaque <i>black box</i> within decision-making processes.…”
Get full text

Modeling peripheral olfactory coding in Drosophila larvae. by Derek J Hoare, James Humble, Ding Jin, Niall Gilding, Rasmus Petersen, Matthew Cobb, Catherine McCrohan

“…This was achieved by creating larvae expressing just one functioning class of odorant receptor, and hence OSN. …”
Get full text

Ionotropic Receptor-dependent cool cells control the transition of temperature preference in Drosophila larvae. by Jordan J Tyrrell, Jackson T Wilbourne, Alisa A Omelchenko, Jin Yoon, Lina Ni

“…Here, we show that early-stage larvae, in which dorsal organ cool cells (DOCCs) are functionally blocked, exhibit similar cool preference to that of wild type late-stage larvae. …”
Get full text

Between Battle and Everyday Life: Female Participants of the Partisan Movement of the Smolensk Region in Ego Documents of the 1940s. by Ksenia Sak

“…The experience of their joining partisan detachments, adaptation, and participation in the “nationwide struggle” is an integral part of the problem of the functioning of society in war conditions. Methods and materials. …”
Get full text

Niceness or toughness? Gendered norms as regulators of employee communication of risks and problems by Kristina Hermansson, Erica Nordlander, Lotta Dellve

“…A work environment in which employees express themselves freely about risks and problems, is a prerequisite for a sustainable and safe working environment. …”
Get full text

An Analysis of Students’ Experience in Using English Learning Application “myON” in Helping Students’ English Learning Process by Fasya Putri Radhiyya, Nazwa Aulia, Syifa Shabrina, Hairunnisa Aulia Putri, Bambang Nur Alamsyah Lubis

“…Hence, it is imperative for the "myON" application to underscore the significance of this tool in the process of English language acquisition by showcasing improved functionalities and enhanced communication capabilities that correspond with user preferences.…”
Get full text

Improper Gaussian Signaling for Two-User MISO-NOMA Systems Considering Hardware Impairments and Imperfect SIC by Hao-Tse Chiu, Fumiaki Maehara

“…To deal with the non-convex log-determinant objective functions, we adopt successive concave quadratic programming (SCQP) to obtain suboptimal results by iterations. …”
Get full text