Transcriptomic and Proteomic Analyses of the Liver and Ileum Identify Key Genes and Pathways Associated with Low and High Groups of Social Genetic Effect of Residual Feed Intake by Patrick Kofi Makafui Tecku, Zhenjian Zhao, Kai Wang, Xiang Ji, Dong Chen, Qi Shen, Yang Yu, Shengdi Cui, Junge Wang, Ziyang Chen, Jia Xue, Guoqing Tang

“…They consumed less overall feed but had a higher intake per visit. Differentially expressed genes and proteins were identified in the liver and ileum and were associated with processes such as mitochondrial functions, oxidative phosphorylation, and cholesterol metabolism. …”
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Identification of hub genes and immune-related pathways in acute myeloid leukemia: insights from bioinformatics and experimental validation by Mingliang Shan, Mingliang Shan, Mingliang Shan, Li Xu, Wenzhe Yang, Shiguo Liu, Zhaoqing Cui

“…Finally, in vitro experiments are conducted to further verify and improve the reliability and physiological functions of the hub gene and its immune-related pathways.ResultsComplement Factor D(CFD) gene is identified as the highly expressed hub gene and is positively correlated with IL-2. …”
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Transformation of 3D Metal–Organic Frameworks into Nanosheets with Enhanced Memristive Behavior for Electronic Data Processing by Yuri A. Mezenov, Semyon V. Bachinin, Yuliya A. Kenzhebayeva, Anastasiia S. Efimova, Pavel V. Alekseevskiy, Daria Poloneeva, Anastasia Lubimova, Svyatoslav A. Povarov, Vladimir Shirobokov, Mikhail S. Dunaevskiy, Aleksandra S. Falchevskaya, Andrei S. Potapov, Alexander Novikov, Artem A. Selyutin, Pascal Boulet, Alena N. Kulakova, Valentin A. Milichko

“…The latter allows to demonstrate the prototype of ultrathin memristive element based on a 4 to 32 nm MOF nanosheet with enhanced functionality (150 to 1400 ON/OFF ratio, retention time exceeding 7300 s, and 100 cycles of switching), thereby, extending the list of scalable and insulating 2D MOFs for micro‐ and opto‐electronics.…”
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A UFD1 variant encoding a microprotein modulates UFD1f and IPMK ubiquitination to play pivotal roles in anti-stress responses by Xiuzhi Li, Xiaolin Wang, Xu Liu, Ge Shan, Liang Chen

“…Here, we identified a mammalian conserved SR-mRNAiso, UFD1s, which encodes a microprotein with anti-stress functions. UFD1s decreased the K63-linked ubiquitination levels of UFD1 full-length protein (UFD1f) via competitive binding to the E3 ubiquitin ligase MARCH7, and therefore regulated the dynamics of protein ubiquitination. …”
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Type 2 Innate Lymphoid Cell in Cardiovascular Diseases: Complexities and Potentials by Haibei Sun, Weizhuo Liu, Zelin Yu, Bin He

“…Abstract Innate lymphoid cells (ILCs) are a class of lymphocytes that do not express specific antigen recognition receptors, which play a significant role in various diseases due to their unique immunomodulatory functions. …”
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Integrative Transcriptomic and Biochemical Analysis Reveals Key HSP20/Alpha-Crystallin Genes Associated with Heat Tolerance in Rice by Mvuyeni Nyasulu, Qi Zhong, Zhengjie Wang, Zhicheng Cheng, Chen Zhihao, Jun Yang, Haohua He, Jianmin Bian

“…These genes play essential roles in protein stabilization, folding, and preventing aggregation, critical functions for maintaining protein balance under stress conditions. …”
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A Hedgehog–Foxf axis coordinates dental follicle-derived alveolar bone formation by Mizuki Nagata, Gaurav T. Gadhvi, Taishi Komori, Yuki Arai, Chiaki Tsutsumi-Arai, Angel Ka Yan Chu, Seth N. Nye, Yuntao Yang, Shion Orikasa, Akira Takahashi, Peter Carlsson, W. Jim Zheng, Joshua D. Welch, Noriaki Ono, Wanida Ono

“…Abstract The alveolar bone is a specialized mineralized structure supporting the lifelong functionality of the tooth in mastication. The alveolar bone develops from the dental follicle (DF) during tooth root formation due to deliberate epithelial–mesenchymal interactions. …”
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Decoding G-Quadruplexes Sequence in <i>Vitis vinifera</i>: Regulatory Region Enrichment, Drought Stress Adaptation, and Sugar–Acid Metabolism Modulation by Jun Xie, Kangkang Song, Gaixia Qiao, Rong Wang, Hongyuan Wu, Qiaoxia Jia, Yujuan Liu, Yi Li, Meilong Xu

“…Here, we comprehensively examined the prevalence and functions of G-quadruplexes in <i>Vitis vinifera</i>. …”
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Modulating the Substrate Stiffness to Manipulate Differentiation of Resident Liver Stem Cells and to Improve the Differentiation State of Hepatocytes by Angela Maria Cozzolino, Valeria Noce, Cecilia Battistelli, Alessandra Marchetti, Germana Grassi, Carla Cicchini, Marco Tripodi, Laura Amicone

“…Furthermore, standard cultivation of liver stem/precursor cells impedes an efficient execution of the epithelial/hepatocyte differentiation program, leading to the expansion of a cell population expressing only partially liver functions and products. …”
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An NVMe-Based Secure Computing Platform With FPGA-Based TFHE Accelerator by Yoshihiro Ohba, Tomoya Sanuki, Claude Gravel, Kentaro Mihara, Asuka Wakasugi, Kenta Adachi

“…We defined secure computing instructions to evaluate 14-bit to 14-bit functions using TFHE. Our middleware allows for the communication of ciphertexts, keys, and secure computing programs while invoking secure computing programs through NVMe commands with metadata. …”
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Echinocandin Adaptation in <i>Candida albicans</i> Is Accompanied by Altered Chromatin Accessibility at Gene Promoters and by Cell Wall Remodeling by Sudisht K. Sah, Anshuman Yadav, Tyler Stahl, Jeffrey J. Hayes, Michael Bulger, Elena Rustchenko

“…We also find that chromatin changes are often associated with differentially expressed genes including genes with functions relevant to the ECN-adapted phenotype, such as cell wall biosynthesis. …”
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USP10 stabilizes BAZ1A to drive tumor stemness via an epigenetic mechanism in head and neck squamous cell carcinoma by Yanni Shi, Jiawei Ding, Xiao Ling, Danfeng Xu, Yan Shen, Xingjun Qin

“…In this study, we identified that ubiquitin-specific peptidase 10 (USP10) is up-regulated in HNSCC tissues, and high USP10 is associated with poor prognosis of patients. Functionally, USP10 serving as an oncogene potentiates the proliferation and metastasis of HNSCC cells in vitro and in vivo. …”
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Evaluation of a Vision-Guided Shared-Control Robotic Arm System with Power Wheelchair Users by Breelyn Kane Styler, Wei Deng, Cheng-Shiu Chung, Dan Ding

“…Wheelchair-mounted assistive robotic manipulators can provide reach and grasp functions for power wheelchair users. This in-lab study evaluated a vision-guided shared control (VGS) system with twelve users completing two multi-step kitchen tasks: a drinking task and a popcorn making task. …”
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GPR37-enhanced ubiquitination of ATP1A1 inhibits tumor progression and radiation resistance in esophageal squamous cell carcinoma by Jiaru Hu, Fang Meng, Lei Lv, Fu Hong, Qing He, Qi Zhu, Tian Tian, Na Chang, Shiqiang Zhang, Qiyi Yi, Liting Qian

“…We found that GPR37 is lowly expressed in ESCC, especially in radioresistant ESCC tumors. …”
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Structure of the Calvin-Benson-Bassham sedoheptulose-1,7-bisphosphatase from the model microalga Chlamydomonas reinhardtii by Théo Le Moigne, Martina Santoni, Lucile Jomat, Stéphane D Lemaire, Mirko Zaffagnini, Nicolas Chéron, Julien Henri

“…We identify active site residues and locate sites of redox- and phospho-post-translational modifications that contribute to enzymatic functions. Finally, we observe that CrSBPase adopts distinct oligomeric states that may dynamically contribute to the control of its activity.…”
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Landscape analysis of m6A modification reveals the dysfunction of bone metabolism in osteoporosis mice by Lifeng Zheng, Chao Lan, Xinyue Gao, An Zhu, Yaoqing Chen, Jinluan Lin, Sunjie Yan, Ximei Shen

“…Numerous studies have underscored the crucial functions of m6A regulators in OP. This study aimed to explore the relationship between OP and RNA m6A methylation, investigating its underlying mechanisms through comprehensive bioinformatic analysis and experimental validation. …”
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Review of sensor fault diagnosis and fault-tolerant control techniques of lithium-ion batteries for electric vehicles by Yang Zhao, Limin Geng, Shiyu Shan, Zeyu Du, Xunquan Hu, Xiaolong Wei

“…Accurate sensor signals, particularly voltage, current, and temperature sensor signals, are essential for a BMS to perform functions such as state estimation, balance control, and fault diagnosis. …”
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Exact Analytical Solutions for Modelling the Speed-Time Characteristics of Direct-Start Induction Machines under Various Operational Conditions on Ships: Review and Experimental Va... by Ilija Knezevic, Martin Calasan, Tatijana Dlabac, Filip Filipovic, Nebojsa Mitrovic

“…Induction machines (IMs) are crucial to driving auxiliary machinery and devices of ships, such as pumps, fans, winches, and elevators, which are essential for maintaining the operational functions of a ship and are characterised by various types of loads. …”
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Structure, Binding Characteristics, and 3D Model Prediction of a Newly Identified Odorant-Binding Protein from the Cotton Bollworm, Helicoverpa armigera (Hübner) by Tian-tao ZHANG, Wei-xuan WANG, Shao-hua GU, Zi-ding ZHANG, Kong-ming WU, Yong-jun ZHANG, Yu-yuan GUO

“…This study provides clues for better understanding physiological functions of OBPs in H. armigera and other insects.…”
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Palmitoylation prevents B7-H4 lysosomal degradation sustaining tumor immune evasion by Yijian Yan, Jiali Yu, Weichao Wang, Ying Xu, Kole Tison, Rongxin Xiao, Sara Grove, Shuang Wei, Linda Vatan, Max Wicha, Ilona Kryczek, Weiping Zou

“…Abstract B7-H4 functions as an immune checkpoint in the tumor microenvironment (TME). …”
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