Decoding the GRAS code: evolutionary phylogeny and functional diversification of a key gene family in Populus simonii by Junbo Chen, Guowei Yao, Xinru Bi, Yishuang Ren, Luping Jiang, Xiaoyu Xie, Lu Han, Wanying Chen, Yi Hao, Kewei Cai, Dandan Zhang, Xiyang Zhao

“…Analysis of cis-acting elements in the promoter regions indicated the presence of multiple regulatory elements associated with light responsiveness, phytohormone signaling, stress tolerance, and developmental regulation. Expression profiling showed that PSGRAS genes exhibit tissue-specific and stress-responsive expression patterns, suggesting their functional diversification in growth, development, and abiotic stress adaptation in Populus simonii. …”
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Identification and Functional Characterization of a Geraniol Synthase UrGES from <i>Uncaria rhynchophylla</i> by Xinghui Liu, Wenqiang Chen, Linxuan Li, Detian Mu, Iain W. Wilson, Xueshuang Huang, Yahui Xiang, Lina Zhu, Limei Pan, Deyou Qiu, Qi Tang

“…Enzymatic assays confirmed that recombinant UrGES catalyzed GPP conversion to a single product of geraniol. The transient expression of <i>UrGES</i> resulted in geraniol accumulation in <i>N. benthamiana</i>, further confirming its function in vivo. …”
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Soil function and "malfunction" by Andrea Buondonno, Elio Coppola

“…In this paper soil importance, even in “environmental and social” terms, is pointed out, considering soil as a natural body with its own functional characteristics, regardless of its agronomic role and productive ability. …”
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Characterization of Gene Expression Suppression by Bovine Coronavirus Non-Structural Protein 1 by Takehiro Ohkami, Ichika Kitashin, Riko Kawashima, Aimi Yoshida, Taizo Saito, Yasuhiro Takashima, Wataru Kamitani, Keisuke Nakagawa

“…Previous studies demonstrated that the nsp1 of various coronaviruses induces host shutoff through a variety of mechanisms; however, there is little information on the function of bovine coronavirus (BCoV) nsp1. We aimed to characterize the host gene expression suppression function of BCoV nsp1. …”
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Maximum lifespan and brain size in mammals are associated with gene family size expansion related to immune system functions by Huseyin Kilili, Benjamin Padilla-Morales, Atahualpa Castillo-Morales, Jimena Monzón-Sandoval, Karina Díaz-Barba, Paola Cornejo-Paramo, Orsolya Vincze, Mathieu Giraudeau, Stephen J. Bush, Zhidan Li, Lu Chen, Evangelos Mourkas, Sergio Ancona, Alejandro Gonzalez-Voyer, Diego Cortez, Humberto Gutierrez, Tamás Székely, Alín P. Acuña-Alonzo, Araxi O. Urrutia

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Immunopathogenetic features of the functioning of congenital immunity in children with dental and disabling somatic pathology by M. A. Havrylenko, Т. Ye. Shumna

“…The pathogenetic signaling pathways for the implementation of the functioning of congenital immunity depending on the disabling disease and the mechanisms of the formation of odontogenic pathology under the conditions of life of non-hemolytic and hemolytic streptococci and corynebacterium in dental plaque and peculiarities of sIgA products, lysozyme: in children with CNS diseases – due to transcriptional activity of membrane tolu- like receptors 4, expression of the nucleic factor kV (NF-κB) and the activity of the matrix RNA of proinflammatory cytokines IL-1β and IL-17A; with blood diseases - when activating matrix RNA of membrane toluic receptors 2, 4, nuclei factor kV (NF-κB), interleukin 17A; with diseases of the respiratory system - expression of interleukin 17A; with mental disorders - when activating interleukin 1β and membrane toll-like receptors by interleukin 17A.…”
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Genomic analysis of COP9 signalosome function in Drosophila melanogaster reveals a role in temporal regulation of gene expression by Efrat Oron, Tamir Tuller, Ling Li, Nina Rozovsky, Daniel Yekutieli, Sigal Rencus‐Lazar, Daniel Segal, Benny Chor, Bruce A Edgar, Daniel A Chamovitz

“…We are using Drosophila as a model system to elucidate the function of this important complex. Transcriptome data were generated for four csn mutants, sampled at three developmental time points. …”
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Abundance-biased codon diversification prevents recombination in AAV production and ensures robust in vivo expression of functional FRET sensors by Jan Dernic, Afroditi Eleftheriou, Lazaros Vasilikos, Melanie Rauch, Pascal Imseng, Henri S. Zanker, Zoe J. Looser, Rachel M. Meister, Felipe Velasquez Moros, Tomer Kagan, Tal Laviv, Jean-Charles Paterna, Michael Arand, Aiman S. Saab, Bruno Weber, Luca Ravotto

“…We demonstrate that ABCD greatly facilitates in vivo studies by restoring the functionality of FRET sensors and advanced inducible expression systems delivered via AAV vectors. …”
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Calculation of the acoustical field of a semi-infinite cylindrical wave-guide by means of the green function expressed in cylindrical coordinates by Anna SNAKOWSKA, Roman WYRZYKOWSKI

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Uncoupling protein 2 and 4 expression pattern during stem cell differentiation provides new insight into their putative function. by Anne Rupprecht, Dana Sittner, Alina Smorodchenko, Karolina E Hilse, Justus Goyn, Rudolf Moldzio, Andrea E M Seiler, Anja U Bräuer, Elena E Pohl

“…Apart from the first family member, uncoupling protein 1 (UCP1), the functions of other UCPs (UCP2-UCP5) are still unknown. …”
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A GLMER-based pedotransfer function expressing the relationship between total organic carbon and bulk density in forest soils by Václav Zouhar, Aleš Kučera, Karel Drápela

“…In such cases, BD can be determined using a pedotransfer function (PTF) expressing the relationship between forest soil TOC and BD. …”
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Expression of inflammatory states in response to psychological distress in breast cancer survivors and its relationship to subjective memory function complaints by Chen Gan, Senbang Yao, Jingjing Zhao, Huangyuxin Shi, Jian Xu, Mingjun Zhang, Huaidong Cheng

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A GLMER-based pedotransfer function expressing the relationship between total organic carbon and bulk density in forest soils by Václav Zouhar, Aleš Kučera, Karel Drápela

“…In such cases, BD can be determined using a pedotransfer function (PTF) expressing the relationship between forest soil TOC and BD. …”
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A Novel Gene RNF138 Expressed in Human Gliomas and Its Function in the Glioma Cell Line U251 by You-xin Zhou, San-song Chen, Ting-feng Wu, Da-dong Ding, Xiong-hui Chen, Jin-ming Chen, Zuo-peng Su, Bin Li, Gui-lin Chen, Xue-shun Xie, Yan-fang Dai, Yong-xin Wei, Zi-wei Du

“…The present study investigates the expression levels of RNF138 mRNA in glioma samples and noncancerous brain samples and its function in the human glioma cell line U251.…”
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Characterization, Expression Profile Analysis, and Functional Prediction of <i>UGP</i> Gene Family in <i>Dendrocalamus brandisii</i> by He Li, Chongyang Wu, Xiangyi Li, Junlei Xu, Zhanchao Cheng, Jian Gao

“…This study suggests that the evolutionarily conserved <i>DbUGPs</i> exhibit mutual coordination and dynamic expression during <i>D. brandisii</i> growth, providing fresh insights into their functional roles.…”
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Long-term persistence of functional thymic epithelial progenitor cells in vivo under conditions of low FOXN1 expression. by Xin Jin, Craig S Nowell, Svetlana Ulyanchenko, Frances H Stenhouse, C Clare Blackburn

“…By reactivating Foxn1 expression postnatally in Foxn1R/- mice we demonstrate that functional TEPCs can persist in the thymic rudiment until at least 6 months of age, and retain the potential to give rise to both cortical and medullary thymic epithelial cells (cTECs and mTECs). …”
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Mannose-B from Codonopsis pilosula modulates LAMB1 expression to enhance trophoblast function and alleviate subchorionic hematoma by Qian Sun, Yuan Gao, Kadirya Asan, Jing Ji, Jinjin Xu, Xiaoyan Wu, Jie Ren, Wen Feng, Mengwei Song, Sen Wang, Boyu Zhang, Ying Zhou, Conghui Han, Shun Liu, Wen Yang

“…Abstract This study investigates the active component Mannose-B from Codonopsis pilosula and its effect on human trophoblast cell function, particularly focusing on the regulation of Laminin Subunit Beta 1 (LAMB1) expression and its implications in subchorionic hematoma (SCH). …”
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A functional variant at a prostate cancer predisposition locus at 8q24 is associated with PVT1 expression. by Kerstin B Meyer, Ana-Teresa Maia, Martin O'Reilly, Maya Ghoussaini, Radhika Prathalingam, Patricia Porter-Gill, Stefan Ambs, Ludmila Prokunina-Olsson, Jason Carroll, Bruce A J Ponder

“…In conclusion, we identified a new functional prostate cancer risk variant at the 8q24 locus, rs378854 allele G, that reduces binding of the YY1 protein and is associated with increased expression of PVT1 located 0.5 Mb downstream.…”
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Oncolytic HSV-IL27 expression improves CD8 T cell function and therapeutic activity in syngeneic glioma models by Alexia K Martin, Uksha Saini, Ilse Hernandez-Aguirre, Yeaseul Kim, Kevin A Cassady, Jack Hedberg, Doyeon Kim, Ravi Dhital

“…We hypothesized that IL-27 expression by oHSV would enhance CTL function and improve antiglioma therapeutic activity.Methods We developed an oHSV that expresses IL-27 (C027). …”
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Noncoding function of super enhancer derived Cpox pre-mRNA in modulating neighbouring gene expression and chromatin interactions by Bingning Xie, Ann Dean

“…Using an erythroid-specific super enhancer that overlaps the Cpox gene as a model, Cpox pre-mRNA is found to have a non-coding function in regulating neighbouring protein-coding genes, eRNA expression and TAD interactions. …”
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