Establishment of political and diplomatic relations between Lithuania and France in 1918-1920: Exchange of mistrust by Vilma Bukaitė

“…The Cabinet of Alexandre Millerand, in function from 20 January 1920, was less tolerant towards the Polish political pressure on Lithuania. …”
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Ema mälestusi lugedes. 1926. aastal sündinud naise meenutused sõjaaegsest ja -järgsest argielust / Everyday Life and Memories of War. The Memories of a Woman Born in 1926 by Anu Korb

“…She wrote down her memories primarily with her descendants in mind, although doing so also had a highly therapeutic function for her. Researchers of cultural memory have observed that we must not underestimate society as an environment of memory. …”
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Utility of 131I-HLX58-Der for the Precision Treatment: Evaluation of a Preclinical Radio-Antibody-Drug-Conjugate Approach in Mouse Models by Liu Y, Wang X, Zhang N, He S, Zhang J, Xu X, Song S

“…The average tumor size in groups treated with 131I-HLX58-Der and HLX58-Der was reduced by factors of 12.15 and 4.80, respectively, compared to the control group. 131I-HLX58-Der demonstrated no toxic effects on hepatorenal function, routine blood tests, or major organs in mice when compared to the control group.Conclusion: These findings validate the potential of RADCs targeting CLDN18.2 in treating CLDN18.2-expressing solid tumors. …”
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Cardiovascular status and echocardiographic changes in survivors of COVID-19 pneumonia three months after hospital discharge by D. V. Krinochkin, E. I. Yaroslavskaya, N. E. Shirokov, E. P. Gultyaeva, I. R. Krinochkina, I. O. Korovina, A. V. Mamarina, N. A. Osokina, N. N. Melnikov, T. A. Trifanova, E. A. Gorbatenko, T. I. Petelina

“…Coronavirus disease 2019 (COVID-19) affects the function of all organs and systems. Today, studying the effect of COVID-19 on cardiovascular system, including on echocardiographic characteristics, is relevant.Aim. …”
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Cardiometabolic Biomarkers and Prediction of Kidney Disease Progression: The eGFR Cohort Study by Elizabeth L. M. Barr, Federica Barzi, Phillip Mills (Kulkalgal), Maria Nickels, Sian Graham, Odette Pearson, Varuni Obeyesekere, Wendy E. Hoy, Graham R. D. Jones, Paul D. Lawton, Alex D. H. Brown, Mark Thomas, Ashim Sinha, Alan Cass, Richard J. MacIsaac, Louise J. Maple-Brown, Jaquelyne T. Hughes (Wagadagam)

“…Conclusions: Cardiovascular, kidney, and inflammatory biomarkers are likely associated with kidney function loss in diabetes, with particularly prominent associations for cardiac injury markers.…”
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Acupuncture combined with language training for aphasia in children with cerebral palsy: a systematic review with meta-analysis and trial sequential analysis by Shuzhen Liu, Shuzhen Liu, Yujiao Li, Yujiao Li, Jun Chang, Jun Chang, Jiangwei Shi, Jiangwei Shi, Lan Zhao, Lan Zhao

“…Acupuncture combined with language training could significantly improve the adaptive behaviour (MD: 7.46; 95% CI: 3.67, 11.26; p = 0.0001), verbal behaviour (MD: 7.79; 95% CI: 5.66, 9.92; p < 0.00001), fine motor behaviour (MD: 4.66; 95% CI: 1.28, 8.03; p = 0.007), and personal social behaviour (MD: 6.47; 95% CI: 2.38, 10.55; p = 0.002); it was also significantly more effective in improving the language comprehension developmental quotient (SMD: 2.02; 95% CI: 1.54, 2.50; p < 0.00001), the expressive language development quotient (SMD: 2.40; 95% CI: 1.76, 3.03; p < 0.00001), assessment of dysarthria (MD: 0.40; 95% CI: 0.11, 0.69; p = 0.007), and oral motor function (SMD: 2.63; 95% CI: 1.36, 3.90; p < 0.0001).ConclusionAcupuncture combined with language training could be an effective treatment for aphasia in children with CP. …”
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Effects of nitrogen levels on soil respiration of sympodial bamboo plantation and factor analysis by LI Weicheng, WANG Shuguang, SHENG Haiyan, ZHENG Youmiao, WANG Shudong, ZHONG Zheke

“…The variation rule of T10, WSOC and SW was similar as this way. Exponential function could be used to describe the relationship between T10 and respiration rate. …”
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NADPH oxidase 1/4 dual inhibition impairs transforming growth factor-beta protumorigenic effects in cholangiocarcinoma cancer-associated fibroblasts by Josep Amengual, Ester Gonzalez-Sanchez, Mariana Yáñez-Bartolome, Laura Sererols-Viñas, Aashreya Ravichandra, Celia Guiton, Noel P. Fuste, Ania Alay, Sara Hijazo-Pechero, Beatriz Martín-Mur, Marta Gut, Anna Esteve-Codina, Ana Cantos-Cortes, Rut Espinosa-Sotelo, Emilio Ramos, Teresa Serrano, Mariona Calvo, Berta Laquente, Joana Ferrer, Gabriel Pons, Andrés Mendez-Lucas, Steven Dooley, Sumera I. Ilyas, Marie Vallette, Lynda Aoudjehane, Marie Lequoy, Laura Fouassier, Cédric Coulouarn, Silvia Affò, Alexander Scheiter, Diego F. Calvisi, Tian V. Tian, Isabel Fabregat, Javier Vaquero

“…NADPH oxidase 4 (NOX4), a downstream mediator of the TGF-β signalling pathway, is strictly expressed in cancer-associated fibroblasts (CAF) of iCCA and acts in concert with NOX1 to regulate CAF functions. …”
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Protease-responsive protein hydrogel enabling spatiotemporal ClO2 release for precision treatment of intracellular infections and periodontitis by Xianxian Huang, Yingjuan Zhang, Yonghui Huang, Qiurui Hu, Zhisong Mai, Yuan Qin, Cui Huang, Yanhua Wei, Fengyuan Zhou, Yicai Luo, Yinge Wei, Xinglu Jiang, Hongbing Liao

“…The synergistic integration of antibacterial and regenerative functions establishes the CD/BSA/GEL hydrogel as a breakthrough platform for precision-guided periodontal therapy.…”
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A novel regulatory axis of MSI2-AGO2/miR-30a-3p-CGRRF1 drives cancer chemoresistance by upregulating the KRAS/ERK pathway by Runhui Lu, Yafan Zhang, Ran Chen, Lian Li, Caihu Huang, Zihan Zhou, Yingting Cao, Hongyan Li, Junya Li, Yixin Zhang, Yanli Wang, Jian Huang, Xian Zhao, Jing Feng, Jianxiu Yu, Chunling Du

“…Specifically, MSI2 recruits UAG-miRNA miR-30a-3p to facilitate its loading onto AGO2, efficiently inhibiting the expression of CGRRF1. Further analysis reveals that CGRRF1 functions as a new ubiquitin E3 ligase for KRAS, mediating the ubiquitination and proteasome degradation of KRAS. …”
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Cinnamaldehyde supplementation in sows and their offspring: effects on colostrum and milk composition, performance, redox status and intestinal health by Junqi Jin, Shiya Liu, Qiang Zhou, Zhengfeng Fang, Yan Lin, Shengyu Xu, Bin Feng, Yong Zhuo, Hefeng Luo, Xiuming Liu, De Wu, Lianqiang Che

“…Moreover, maternal CA supplementation or post-weaning CA supplementation improved nutrient digestibility, redox status, and intestinal function-related parameters of weaned piglets.…”
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Conversion of T Effector Cells Into T Regulatory Cells in Type 1 Diabetes/Latent Autoimmune Diabetes of Adults by Inhibiting eIF5A and Notch Pathways by Rafiqi SI, Aldasouqi A, Paparodis RD, Dewan S, Farooqi A, Faisal S, Nemat Y, Salim N, Qureshi S, Mahmood A, Tovar Y, Jun JY, Kalinoski AL, Mirmira RG, Jaume JC, Imam S

“…University of Toledo, Toledo, OH, 43614-2598, USA, Tel +1 419-383-3786, Email shahnawaz.imam@utoledo.eduBackground: The generation of functionally active, stable T regulatory cells (Tregs) is a crucial target of type 1 diabetes (T1D) immunotherapy. …”
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m6A-methylase METTL3 promotes retinal angiogenesis through modulation of metabolic reprogramming in RPE cells by Qian Zhou, Xianyang Liu, Huiping Lu, Na Li, Jiayu Meng, Jiaxing Huang, Zhi Zhang, Jiangyi Liu, Wei Fan, Wanqian Li, Xingran Li, Xiaoyan Liu, Hangjia Zuo, Peizeng Yang, Shengping Hou

“…Our analysis revealed that retinal pigment epithelium (RPE) cells serve a crucial promotional function in angiogenesis. RPE cells were regulated by N6-methyladenosine (m6A). …”
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Impact of single nucleotide polymorphisms of immunomodulatory factors on treatment response and prognosis in acute myeloid leukemia by Mingying Li, Mingying Li, Tao Sun, Tao Sun, Mengyuan Chang, Mengyuan Chang, Tingting Liu, Tingting Liu, Lei Feng, Lei Feng, Di Zhang, Di Zhang, Yuyan Wu, Yuyan Wu, Yuechan Ma, Yuechan Ma, Huixian Ma, Guangqiang Meng, Guangqiang Meng, Chunyan Ji, Chunyan Ji, Jingjing Ye, Jingjing Ye

“…BackgroundAcute myeloid leukemia (AML) is a hematologic malignancy characterized by poor overall survival (OS). The impaired function, altered phenotype, and abnormal distribution of T cells create an immunosuppressive microenvironment in AML, affecting the efficacy of chemotherapy. …”
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GPATCH11 variants cause mis-splicing and early-onset retinal dystrophy with neurological impairment by Andrea Zanetti, Gwendal Dujardin, Lucas Fares-Taie, Jeanne Amiel, Jérôme E. Roger, Isabelle Audo, Matthieu P. Robert, Pierre David, Vincent Jung, Nicolas Goudin, Ida Chiara Guerrera, Stéphanie Moriceau, Danielle Amana, Nurit Assia Batzir, Anat Bachar-Zipori, Lina Basel Salmon, Nathalie Boddaert, Sylvain Briault, Ange-Line Bruel, Christine Costet-Fighiera, Luisa Coutinho Santos, Cyril Gitiaux, Karolina Kaminska, Paul Kuentz, Naama Orenstein, Nicole Philip-Sarles, Morgane Plutino, Mathieu Quinodoz, Cristina Santos, Sabine Sigaudy, Mariana Soeiro e Sá, Efrat Sofrin, Ana Berta Sousa, Rui Sousa-Luis, Christel Thauvin-Robinet, Erwin L. van Dijk, Khaoula Zaafrane-Khachnaoui, Dinah Zur, Josseline Kaplan, Carlo Rivolta, Jean-Michel Rozet, Isabelle Perrault

“…Our results reveal a subcellular localization of GPATCH11 characterized by a diffuse presence in the nucleoplasm, as well as centrosomal localization, suggesting potential functions in RNA and cilia metabolism. Transcriptomic analysis performed on mouse retina detect dysregulation in both gene expression and splicing activity, impacting key processes such as photoreceptor light responses, RNA regulation, and primary cilia-associated metabolism. …”
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Opposite Roles of IL-32α Versus IL-32β/γ Isoforms in Promoting Monocyte-Derived Osteoblast/Osteoclast Differentiation and Vascular Calcification in People with HIV by Hardik Ramani, Aurélie Cleret-Buhot, Mohamed Sylla, Rémi Bunet, Florent Bertrand, Marc-Messier Peet, Carl Chartrand-Lefebvre, Benoit Trottier, Réjean Thomas, Jean-Pierre Routy, Claude Fortin, Valérie Martel-Laferrière, Manel Sadouni, Guy Cloutier, Louise Allard, Jorge R. Kizer, Nicolas Chomont, Petronela Ancuta, David B. Hanna, Robert C. Kaplan, Mohammad-Ali Jenabian, Alan L. Landay, Madeleine Durand, Mohamed El-Far, Cécile L. Tremblay

“…Here, we show that while the less expressed IL-32α isoform induces the differentiation of human classical monocytes into the calcium-resorbing osteoclast cells, the dominantly expressed isoforms IL-32β and IL-32γ suppress this function through the inhibition of TGF-β and induce the differentiation of monocytes into the calcium-depositing osteocalcin+ osteoblasts. …”
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Unveiling IRF4-steered regulation of context-dependent effector programs in CD4+ T cells under Th17- and Treg-skewing conditions by Anna Gabele, Maximilian Sprang, Mert Cihan, Mareen Welzel, Assel Nurbekova, Karolina Romaniuk, Sarah Dietzen, Matthias Klein, Georg Bündgen, Maxim Emelianov, Gregory Harms, Krishnaraj Rajalingam, Tanja Ziesmann, Katrin Pape, Beatrice Wasser, David Gomez-Zepeda, Kathrin Braband, Michael Delacher, Niels Lemmermann, Stefan Bittner, Miguel A. Andrade-Navarro, Stefan Tenzer, Katja Luck, Tobias Bopp, Ute Distler

“…Summary: The transcription factor interferon regulatory factor 4 (IRF4) is crucial for the fate determination of pro-inflammatory T helper (Th) 17 and the functionally opposing group of immunomodulatory regulatory T (Treg) cells. …”
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Molecular and genetic evidence for the role of AMBRA1 in suppressing S-phase entry and tumorigenesis by Hisako Akatsuka, Tomohiro Kashikawa, Kaori Masuhara, Mizuki Tokusanai, Chenyang Li, Yumi Iida, Chisa Okada-Yamaguchi, Yoshinori Okada, Masayuki Tanaka, Takahiro Suzuki, Norio Yamamoto, Katsuto Hozumi, Tomoaki Tanaka, Hirofumi Nakaoka, Kazuyoshi Hosomichi, Yu Hamaguchi, Michiaki Hamada, Yoshiki Shiraishi, Akihide Kamiya, Yoshihiko Nakamura, Kaito Harada, Abd Aziz Ibrahim, Takashi Yahata, Masato Ohtsuka, Naoya Nakamura, Hiroyuki Hosokawa, Minoru Kimura, Ituro Inoue, Takehito Sato

“…Summary: AMBRA1, which was initially reported to be essential for nervous system development via autophagy and cell proliferation control, also functions as a tumor suppressor by regulating the ubiquitination of D-type cyclins through interaction with DDB1-Cullin4A/4 B E3 ligase. …”
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The Analysis of the Effective Factors on Urban Blight in District 3, Region 12, Tehran City by Hossein Mansourian, Ahmad Pour Ahmad, Hasan Ashouri

“…In accordance with population growth and physical extension, the central part of Tehran has experienced many changes including the movements of original inhabitants and resettled immigrants, changes in the combination and variety of urban land use making them the backup land uses of some of the original ones, coincidence of functional fatigue and physical fatigue, the increase of crime and social harms, and the decrease of the level of public services required by inhabitants. …”
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Overall Layout Method of Frame Structure Plane Based on Generative Adversarial Network by ZHONG Yan, LEI Xin, LONG Danbing, FANG Changjian, KANG Yongjun

“…The model’s generated frame columns met functional requirements, were well-placed, and had appropriate size and density. …”
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