Efectividad de una metodología para contribuir a la habilidad de solucionar problemas en la asignatura Embriología Médica by Elena Vicenta Hernández Navarro, Jorge Luis Losada Guerra, Lizette Elena Leiva Suero, Marcelo Mantilla-Falcón

“…Conclusion: The methodology application was effective about the favorable transformation of dimensions and indicators of problem-solving skill, expressed in higher levels of mastery in functional invariants execution of the skill by the students.…”
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Language and ethnicity in Central and Eastern Europe: Some theoretical aspects by George Schopflin

“…The author concludes that language has played both a symbolic and a functional role in the centralisation of Central and Eastern Europe. …”
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Novel predictive biomarkers for atonic postpartum hemorrhage as explored by proteomics and metabolomics by Jiangxue Qu, Hai Jiang, Huifeng Shi, Nana Huang, Jiawen Su, Yan Zhang, Lian Chen, Yangyu Zhao

“…Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) functional enrichment analysis of significantly differentially expressed proteins revealed that atonic PPH was associated with T cell- and macrophage-related immune inflammatory responses. …”
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Принципи ергодизайнерського забезпечення проектування авіаційних систем та заходи з їх реалізації... by Anatoly Rubtsov, Vladimir Svirko, Ivan Otroumov

“…Each of them has its own ergo design content and needs to be relieved to take into account the «human factor» component — from improving the safety and efficiency of aviation systems to ensuring the required level of functional comfort of service personnel. It specifies the aim of the article: identification of the basic principles of the ergdesign and operation of aircraft systems and ways of their implementation. …”
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Some Human Anti-Glycan Antibodies Lack the Ability to Activate the Complement System by Nadezhda Shilova, Alexey Nokel, Alexander Lipatnikov, Nailya Khasbiullina, Yuri Knirel, Ludmila Baidakova, Alexander Tuzikov, Sergei Khaidukov, Polina Obukhova, Stephen Henry, Batozhab Shoibonov, Emin Salimov, Robert Rieben, Nicolai Bovin

“…</b> Thus, ~30% of human anti-glycan antibodies lack the ability to activate the complement system. The function of the widely represented immunoglobulins that do not cause C3 deposition remains unclear.…”
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Single‐cell landscape of the intrahepatic ecosystem in alcohol‐related liver disease by Xiaofang Zhao, Senyan Wang, Qi Liu, Wenjuan Wei, Xiaoyan Sun, Hao Song, Jing Xu, Shuijun Zhang, Hongyang Wang, Jing Fu

“…The ALB+ KRT7+ epithelium were enriched in ALD patients, and the function of this epithelial population varied significantly across ALD stages. …”
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Verification of Lactobacillus brevis tolerance to simulated gastric juice and the potential effects of postbiotic gamma-aminobutyric acid in streptozotocin-induced diabetic mice by Amro Abdelazez, Heba Abdelmotaal, Smith Etareri Evivie, Maha Bikheet, Rokayya Sami, Hassan Mohamed, Xiangchen Meng

“…The study aims to investigate the function of Lactobacillus brevis KLDS1.0727 and KLDS1.0373 strains as glutamic acid decarboxylase 65 (GAD65) carriers capable of generating GABA by comparing in vitro free and freeze-dried models and GABA intervention in vivo. …”
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Primary failure of eruption: From molecular diagnosis to therapeutic management by Delphine Wagner, Tristan Rey, Marie-Cécile Maniere, Sarah Dubourg, Agnès Bloch-Zupan, Marion Strub

“…Results: The clinical phenotype (type and number of involved teeth, depth of bone inclusions, functional consequences) is variable within the family. …”
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Bioinformatics Analysis of Diadenylate Cyclase Regulation on Cyclic Diadenosine Monophosphate Biosynthesis in Exopolysaccharide Production by <i>Leuconostoc mesenteroides</i> DRP10... by Wenna Yu, Liansheng Yu, Tengxin Li, Ziwen Wang, Renpeng Du, Wenxiang Ping

“…Lactic acid bacteria exopolysaccharides (EPS) have a variety of excellent biological functions and are widely used in the food and pharmaceutical industries. …”
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Patient-reported Outcome Measures and Decision Regret After Prostate-specific Membrane Antigen–targeted Radioguided Surgery for Oligorecurrent Prostate Cancer by Fabian Falkenbach, Giovanni Mazzucato, Zhe Tian, Pierre I. Karakiewicz, Markus Graefen, Thomas Steuber, Derya Tilki, Daniel Koehler, Burkhard Beyer, Pierre Tennstedt, Sophie Knipper, Lars Budäus, Tobias Maurer

“…Conclusions and clinical Implications: We recorded no significant decrease in quality of life or any functional status domain, except sexual. While decision regret was low, sexual functioning might deteriorate further. …”
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Application of Jane Jacobs’ Theory in the Analysis of the Borders of Territory Monitoring in Urban Spaces from Citizens’ Points of View in Bandar Abbas by Amirhamzeh Shahbazi, Esmaeil zakerimnabi, Alireza Shahbazi

“…The study sought to identify and analyze the mental boundaries and functional areas of monitoring that manifested in citizens' behavioral patterns. …”
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β2 integrin regulates neutrophil trans endothelial migration following traumatic brain injury by Lei Li, Ruilong Peng, Cong Wang, Xin Chen, Dilmurat Gheyret, Siyu Guan, Bo Chen, Yafan Liu, Xilei Liu, Yiyao Cao, Cha Han, Jianhua Xiong, Fanjian Li, Taoyuan Lu, Haoran Jia, Kaiji Li, Jinchao Wang, Xu Zhang, Jianye Xu, Yajuan Wang, Xin Xu, Tuo Li, Jianning Zhang, Shu Zhang

“…The treatment has demonstrated significant improvements in neurologic function in TBI mice, attenuating blood–brain barrier permeability, mitigating oxidative stress and inflammatory mediator release, and enhancing cerebral perfusion. …”
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Elucidating the role of PPARG inhibition in enhancing MERS virus immune response: A network pharmacology and computational drug discovery by Ahmed M. Hassan, Leena H. Bajrai, Azzah S. Alharbi, Meshari M. Alhamdan, Vivek Dhar Dwivedi, Esam I. Azhar

“…Understanding MERS's genetic underpinnings and potential therapeutic targets is crucial for developing effective treatments. Methods: Two gene expression datasets (GSE81909 and GSE100504) were analyzed to identify differentially expressed genes (DEGs) using GEO2R. …”
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Candidate Phyla Radiation (CPR) bacteria from hyperalkaline ecosystems provide novel insight into their symbiotic lifestyle and ecological implications by Yu He, Shiyan Zhuo, Meng Li, Jie Pan, Yongguang Jiang, Yidan Hu, Robert A. Sanford, Qin Lin, Weimin Sun, Na Wei, Shuming Peng, Zhou Jiang, Shuyi Li, Yongzhe Li, Yiran Dong, Liang Shi

“…Additionally, two presumed auxotrophic hosts, incapable of forming tetrahydrofolate (THF) due to the absence of folA, were identified as potential hosts for some CPR bacteria harboring folA genes. The functionality of these CPR-derived folA genes was experimentally verified by heterologous expression in the folA-deletion mutant Escherichia coli MG1655 ΔfolA. …”
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Matrix stiffness-dependent PD-L2 deficiency improves SMYD3/xCT-mediated ferroptosis and the efficacy of anti-PD-1 in HCC by Shunxi Wang, Xiaoxue Yuan, Zetao Yang, Xuan Zhang, Zhiling Xu, Li Yang, Xian Yang, Wei Zhou, Wanqian Liu

“…Results: Here, we revealed that matrix stiffness-induced PD-L2 functions as a suppressor of xCT-mediated ferroptosis to promote cancer growth and sorafenib resistance in patients with HCC. …”
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Comprehensive analysis of nasal IgA antibodies induced by intranasal administration of the SARS-CoV-2 spike protein by Kentarou Waki, Hideki Tani, Eigo Kawahara, Yumiko Saga, Takahisa Shimada, Emiko Yamazaki, Seiichi Koike, Yoshitomo Morinaga, Masaharu Isobe, Nobuyuki Kurosawa

“…Our investigation is the first to demonstrate the function of nasal IgA at the monoclonal level, showing that nasal immunization can provide effective immunity against SARS-CoV-2 by inducing multimeric secretory IgAs at the target site of the virus infection.…”
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Targeted inhibitors of S100A9 alleviate chronic pancreatitis by inhibiting M2 macrophage polarization via the TAOK3-JNK signaling pathway by Xufeng Tao, Yu Wu, Yu Wu, Fangyue Guo, Fangyue Guo, Linlin Lv, Xiaohan Zhai, Dong Shang, Dong Shang, Dong Shang, Zhan Yu, Hong Xiang, Hong Xiang, Deshi Dong

“…CP’s microenvironment disrupts the fine-tuned balance of macrophage polarization toward a predominance of the M2-like phenotype associated with fibrosis. S100A9 is mainly expressed in monocytes as a potent regulator of macrophage phenotype and function. …”
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Toxoplasma gondii virulence in mice is determined by the pseudokinase ROP5B and countered by an IRG-GBP protein interplay by Shishir Singh, Shishir Singh, Shishir Singh, Mateo Murillo-León, Mateo Murillo-León, Mateo Murillo-León, Mateo Murillo-León, Mateo Murillo-León, Aura María Bastidas Quintero, Aura María Bastidas Quintero, Florence Melbert, Florence Melbert, Klaus Pfeffer, Daniel Degrandi, Tobias Steinfeldt, Tobias Steinfeldt

“…The same parasite effectors that inhibit IRG protein accumulation and function reduce the vacuolar amount of Guanylate Binding Proteins (GBP proteins). …”
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RANKL blockade inhibits cancer growth through reversing the tolerogenic profile of tumor-infiltrating (plasmacytoid) dendritic cells by Pascale Hubert, Patrick Roncarati, Charlotte Pilard, Marie Ancion, Celia Reynders, Thomas Lerho, Diane Bruyere, Alizee Lebeau, Marie-Julie Nokin, Elodie Hendrick, Olivier Peulen, Philippe Delvenne, Michael Herfs, Margaux Luyckx, Michael Renard, Florian Poulain, Rebekah Crake, Raphael Peiffer

“…Finally, the impact of RANKL on the functionality of both dendritic cells (DC) and plasmacytoid dendritic cells (pDC) was determined.Results A drastic tumor growth inhibition was reproductively observed following RANKL inhibition. …”
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Exhaled breath particles as a diagnostic tool for bronchiolitis obliterans syndrome in lung transplant recipients: a longitudinal study by Runchuan Gu, Runchuan Gu, Runchuan Gu, Embla Bodén, Embla Bodén, Embla Bodén, Embla Bodén, Sandra Lindstedt, Sandra Lindstedt, Sandra Lindstedt, Sandra Lindstedt, Franziska Olm, Franziska Olm, Franziska Olm, Franziska Olm

“…PFR could be used as a new diagnostic tool for BOS and to follow the development of lung function over time.…”
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