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27121
Implementation of global soil databases in the Noah-MP model and the effects on simulated mean and extreme soil hydrothermal changes
Published 2025-06-01“…However, the results underscore the need for greater collaborative efforts to develop more detailed regionally derived soil texture characteristics and to improve pedotransfer function (PTF) parameterizations for better representations of soil properties in LSMs. …”
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27122
UNEXPECTED SPONTANEOUS REGRESSION IN CLL AFTER LETROZOLE TREATMENT: COINCIDENCE OR CONNECTION?
Published 2025-07-01“…Estrogen is known to influence B-cell function and survival, particularly through its interaction with Estrogen Receptors (ER). …”
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27123
Contribution of entropy analysis on three-dimensional Prandtl model under Hall and ion slip effects with generalized mass and heat fluxes via OHAM
Published 2025-03-01“…It is noticed that velocity distribution along x-axes is an increasing function of magnetic constraint, Prandtl fluid and also elastic constraint whilst contrast impact is seen along y-axes. …”
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27124
Protective Effects of Konjac and Inulin Extracts on Type 1 and Type 2 Diabetes
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27125
Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value.
Published 2008-05-01“…In the overall group of French subjects (4,232 T2D and 4,595 NGT), IGFBP2 and CXCR4 synergistically interacted with (LOC38776, SLC30A8, HHEX) and (NGN3, CDKN2A/2B), respectively, encoding for proteins presumably regulating pancreatic endocrine cell development and function. The T2D risk increased strongly when risk alleles, including the previously discovered T2D-associated TCF7L2 rs7903146 SNP, were combined (8.68-fold for the 14% of French individuals carrying 18 to 30 risk alleles with an allelic OR of 1.24). …”
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27126
Formulated Mathematical Model for Delayed Particle Flow in Cascaded Subsurface Water Reservoirs with Validation on River Flow
Published 2022-01-01“…The concentration xt of pollutants was expressed as a function of the inflow and outflow rates using the principle for the conservation of mass. …”
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27127
Yangke powder alleviates OVA-induced allergic asthma by inhibiting the PI3K/AKT/NF-κB signaling pathway
Published 2025-05-01“…The asthma model was evaluated using ovalbumin (OVA) and pulmonary function tests, while pathological examination was conducted using hematoxylin and eosin (HE), periodic acid-Schiff (PAS), and Masson trichrome stains. …”
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27128
Reading the Sufi Discourse in the Patterns and Design of Heriz Carpets: A Study from the Late 13th to the Late 14th Century
Published 2025-06-01“…The results suggest that Sufi discourse influenced designs of these carpets a also altered their function. These carpets were not produced as mere floor coverings but rather served as visual narratives of the intellectual and ideological system of the community involved, aimed at preserving and expressing esoteric beliefs. …”
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27129
Multi-targeted olink proteomics analyses of cerebrospinal fluid from patients with aneurysmal subarachnoid hemorrhage
Published 2024-11-01“…Cluster analysis exhibited significant differences in differential proteins between the two groups. GO function enrichment analysis hinted that the differential proteins pertinent to neurology in the CSF of SAH patients were mainly involved in the regulation of defense response, vesicle-mediated transport and regulation of immune response; while the differential proteins related to inflammation were largely connected with the cellular response to chemokine, response to chemokine and chemokine-mediated signaling pathway. …”
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27130
Feasibility of teleyoga for people with post COVID-19 condition– a mixed method design
Published 2025-01-01“…After 7 weeks of teleyoga there was a significant improvement in cognitive function (p-value = 0.048). No differences were found in the physical tests, health-related quality-of-life, anxiety and depression, sleep or in exercise motivation. …”
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27131
Uncovering key markers and therapeutic targets for renal fibrosis in diabetic kidney disease through bulk and single-cell RNA sequencing
Published 2025-07-01“…In the STZ mouse model, PROM1 correlated with fibrosis and diminished renal function, whereas THY1 exhibited protective effects. …”
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27132
Discursive Strategies of Indirect Apology in English-Language Personal Communication
Published 2021-09-01“…In situations of indirect apology, as compared with the direct apology scenario, the replacement of a request for forgiveness by means of one or several speech actions is observed, which confirms the hypothesis of their compensating function in English-speaking interpersonal communication. …”
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27133
Acoustic Features for Identifying Suicide Risk in Crisis Hotline Callers: Machine Learning Approach
Published 2025-04-01“…Basic acoustic features (eg, Mel Frequency Cepstral Coefficients, formant frequencies, jitter, shimmer) and high-level statistical function (HSF) features (using OpenSMILE [Open-Source Speech and Music Interpretation by Large-Space Extraction] with the ComParE 2016 configuration) were extracted. …”
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27134
Comparison of surgical treatments for hip and knee periprosthetic joint infections using the desirability of outcome ranking in a prospective multicentre study
Published 2025-03-01“…A desirability of outcome ranking for PJI (DOOR-PJI) unifies joint function, infection cure and mortality into one outcome. …”
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27135
Algorithmic Literacy and the Role of Librarians in Its Education
Published 2025-02-01“…All digital technologies are algorithmic machines and depend on algorithms to function. Now that we are in the era of artificial intelligence and artificial intelligence systems are built on the basis of algorithms, the need for literacy in relation to algorithms is felt more and more under the title of "algorithmic literacy". …”
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27136
Patients’ and Health Care Professionals’ Expectations of Virtual Therapeutic Agents in Outpatient Aftercare: Qualitative Survey Study
Published 2025-03-01“…The monitoring of health status was viewed positively by both groups. A biofeedback function was desired to detect early warning signs of disease. …”
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27137
Depalmitoylase ABHD16A negatively regulates the anti-hepatitis B virus activity of IFITM1
Published 2025-07-01“…Collectively, our findings demonstrated for the first time that ABHD16A catalyzes the depalmitoylation of IFITM1 to regulate its antiviral activity against HBV, which expands the biological functions of ABHD16A in immune regulation and provides potential targets for HBV infection-related disease therapy.IMPORTANCENowadays, hepatitis B virus (HBV) infection remains a major global public health problem, with over 375 million people worldwide having been infected. …”
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27138
In-vitro immunomodulatory efficacy of extracellular vesicles derived from TGF-β1/IFN-γ dual licensed human bone marrow mesenchymal stromal cells
Published 2025-07-01“…Compared to EVs from non-licensed MSCs, licensed EVs induced a greater proportion of regulatory T cells and exhibited enhanced suppression of allogeneic T cell proliferation. t-SNE analysis revealed a distinct immunoregulatory signature induced by licensed EVs, characterized by the emergence of a non-proliferative lymphocyte subset with elevated co-expression of CD4, CD25, and FOXP3. Transcriptomic analysis further revealed seven overlapping DEGs between IFN-γ– and TGF-β1–licensed MSCs, including both upregulated (GPR68, LIMK2, LIPG) and downregulated (EFNA5, PRKG1, DCLK1, TRIM2) genes, several of which are functionally implicated in EV-mediated immune regulation. …”
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27139
Molecular mechanisms of arecoline-induced oral cancer: a network toxicology and molecular docking techniques integrated analysis
Published 2025-05-01“…Enrichment analysis comprehensively elucidated the molecular functions, biological processes, cellular components, and associated pathways of these overlapping targets. …”
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27140
o8G-modified circPLCE1 inhibits lung cancer progression via chaperone-mediated autophagy
Published 2025-03-01“…The biological functions of circPLCE1 in vivo and in vitro were clarified via establishing a circPLCE1 silencing/overexpression system. …”
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