Friend or foe? Attitudes of rice farmers toward wild animals in West Africa by Patrícia Chaves, Marije Schaafsma, Djunco Dabo, Judite Z. Lomba, Fode Mane, Ricardo F. de Lima, Jorge M. Palmeirim, Ricardo Rocha, Sambu Seck, Justino Biai, Sérgio Timóteo, Christoph F. J. Meyer, Ana Rainho

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Lactiplantibacillus plantarum 299v supplementation modulates β-cell ER stress and antioxidative defense pathways and prevents type 1 diabetes in gluten-free BioBreeding rats by Pinar Sargin, Mark F. Roethle, Shuang Jia, Tarun Pant, Ashley E. Ciecko, Samantha N. Atkinson, Nita H. Salzman, Ru-Jeng Teng, Yi-Guang Chen, Susanne M. Cabrera, Martin J. Hessner

“…Since Lactiplantibacillus plantarum 299 v (Lp299v) supplementation improves gut barrier function and reduces systemic inflammation, we studied its effects in spontaneously diabetic DRlyp/lyp rats provided a normal cereal diet (ND) or a gluten-free hydrolyzed casein diet (HCD). …”
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Unveiling Salt Tolerance Mechanisms and Hub Genes in Alfalfa (<i>Medicago sativa</i> L.) Through Transcriptomic and WGCNA Analysis by Fengdan Wang, Hanfu Wu, Mei Yang, Wen Xu, Wenjie Zhao, Rui Qiu, Ning Kang, Guowen Cui

“…Among these, 2164 DEGs shared the same expression trend, with GO functions enriched in response to oxidative stress, nucleus, plasma membrane, and others. …”
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DEFORMATION OF THE MELODRAMA GENRE IN UKRAINIAN POSTMODERN LITERATURE: IREN ROZDOBUDKO AND NATALIA HURNYTSKA by Olha O. Lilik, Olena V. Sazonova

“…There is a shift in emphasis from dialogues to internal monologues, from plot vicissitudes to character images (there is an emphasis on character images, in particular, female rebels functioning within “formulaic” plots and situations). …”
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Genome-wide association study identifies candidate SNP markers and genes associated with low nitrogen tolerance in Brassica napus by Jingdong Chen, Jingdong Chen, Lingli Xie, Xianfei Hou, Rui Yang, Jin Liu, Xigang Dai, Tianyuan Xue, Shuai Yin, Benbo Xu, Xuekun Zhang, Changli Zeng, Jinsong Xu

“…Gene Ontology analysis revealed enrichment in nitrogen compound transport functions. Several genes such as NPF2.10, ATG4a, and AATL1 were implicated in nitrogen uptake, transport, remobilization, and stress adaptation. …”
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SIRT7-mediated NRF2 deacetylation promotes antioxidant response and protects against chemodrug-induced liver injury by Tingzi Yu, Cong Ding, Jinying Peng, Gaoshuang Liang, Yongyi Tang, Jinqiu Zhao, Zhuan Li

“…Lysine-arginine mutations of these sites (2KR NRF2) significantly reduced KEAP1/NRF2 binding, increased NRF2 nuclear translocation and target gene expression, decreased intercellular ROS level, whereas lysine-glutamine (2KQ) mutant showed similar subcellular localization and functions with WT. …”
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Ribosomal modification protein rimK-like family member A activates betaine-homocysteine S-methyltransferase 1 to ameliorate hepatic steatosis by Han Yan, Wenjun Liu, Rui Xiang, Xin Li, Song Hou, Luzheng Xu, Lin Wang, Dong Zhao, Xingkai Liu, Guoqing Wang, Yujing Chi, Jichun Yang

“…RIMKLA expression was reduced in livers of human and mouse with NAFLD. …”
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GLUT3 enhances chemosensitivity in glioblastoma by transporting temozolomide and capecitabine by Honglin Diao, Yuxin Sun, Xiaojia Zhou, Qikai Wang, Mingyue Wang, Keyu Chen, Zhihua Huang, Jianlei Wei, Zeping Li, Yaxin Lou, Zebin Mao, Wenhua Yu

“…GLUT3, which is highly expressed in GBM and primarily functions as a glucose transporter, has emerged as a promising therapeutic target. …”
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Phytophthora alni Infection Reinforces the Defense Reactions in Alnus glutinosa-Frankia Roots to the Detriment of Nodules by Mathilde Vincent, Hasna Boubakri, Pascale Fournier, Nicolas Parisot, Pierre Pétriacq, Cédric Cassan, Amélie Flandin, Guylaine Miotello, Jean Armengaud, Anne-Emmanuelle Hay, Aude Herrera-Belaroussi

“…Alnus glutinosa, able to establish symbiosis with mutualistic bacteria of the genus Frankia, is one of the main species in European riparian environments, where it performs numerous biological and socioeconomic functions. However, riparian ecosystems face a growing threat from Phytophthora alni, a highly aggressive waterborne pathogen causing severe dieback in A. glutinosa. …”
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Carnosine Synthase (<i>Ts</i>ATPGD) Alleviates Lipid Peroxidation Under Transcriptional Control by an <i>Nfe2</i>-like Gene in <i>Tridacna Squamosa</i> by Zhuo Yang, Nai-Kei Wong, Fan Mao, Siwei Wu, Wenjie Yi, Ziniu Yu, Yang Zhang

“…Gene structure and phylogenetic analysis reveal that <i>T. squamosa</i> possesses a single transcription factor <i>Ts</i>Nfe2l in contrast to mammalian Nfe2l1 (Nrf1) and Nfe2l2 (Nrf2), belonging to protein members of the bZIP-NFE2 subfamily and functionally resembling the mammalian Nfe2l1. A conserved bZIP domain permits its binding to the antioxidant response element (ARE) in vitro and in HEK293T cells. …”
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c-Myc promotes metabolic reprogramming in pulmonary hypertension via the stimulation of glutaminolysis and the reductive tricarboxylic acid cycle by Manivannan Yegambaram, Xutong Sun, Qing Lu, Alejandro Garcia Flores, Marina Zemskova, Jamie Soto, Adam Rauckhorst, Emin Maltepe, Ting Wang, Jeffrey R. Fineman, Stephen M. Black

“…Additionally, c-Myc overexpression impacted the ATP production rate, disrupted mitochondrial respiration, increased reactive oxygen species production, induced cell proliferation, and suppressed apoptosis. Functionally, these metabolic changes suppressed nitric oxide (NO) production. …”
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Obesity-Derived Biomolecules Promote the Differentiation of THP1 Monocytes to Macrophages In Vitro by Luis I. Terrazas, Valeria Gutiérrez-Almaraz, Valentina García-Garay, Victoria Hernández-Gómez, Nohemí Salinas-Jazmín, Mónica Graciela Mendoza-Rodríguez, Jonadab Efraín Olguín

“…Background: It is well known that the microenvironment in which an immune response develops, generally pro-inflammatory or immunosuppressive, along with other overproduced biomolecules recognized by pattern recognition receptors, may promote the stimulation and differentiation of monocytes into macrophages with effector functions. Low-density lipoprotein (LDL) plays a fundamental role in cholesterol transport. …”
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Insights into Lead Toxicity and Detoxification Mechanisms in the Silkworm, <i>Bombyx mori</i> by Dan-Dan Bian, Yan-Xia Shi, Kai-Wen Shi, Hui-Cong Du, Bo-Ping Tang, Qiu-Ning Liu

“…KEGG enrichment analysis highlighted the involvement of these DEGs in drug metabolism, glutathione metabolism, and ABC transporter pathways (<i>p</i> < 0.05). Functional validation showed that knocking down Cap ‘n’ Collar C (CncC) significantly suppressed key detoxification genes (<i>CYP18A1</i>, <i>CYP332A1</i>, <i>GSTd3</i>, <i>GSTt1</i>, <i>UGT33D8</i>; <i>p</i> < 0.05). qRT-PCR and Western blot analyses confirmed that the Caspase-3 pathway mediates Pb-induced apoptosis, with increased cleaved Caspase-3 and Caspase-4 levels following CncC silencing. …”
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SPI1+CD68+ macrophages as a biomarker for gastric cancer metastasis: a rationale for combined antiangiogenic and immunotherapy strategies by Hong Yu, Yulong He, Changhua Zhang, Zhenzhen Zhao, Guofei Deng, Pengliang Wang, Rishun Su, Xuezeng Sun, Zizhen Wu, Zhangsen Huang, Liang Gu, Mingyu Huo, Songcheng Yin

“…Chromatin immunoprecipitation was used to verify the mechanism of SPI1 transcriptional function. The effect of combined antiangiogenic and immunotherapy was further validated using mouse peritoneal metastasis models.Results Single-cell transcriptome analysis and immunohistochemistry demonstrated that SPI1 was expressed in macrophages, with a higher enrichment in metastatic lesions than in primary tumors. …”
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Some key problems on estimation of height of water-conducting fractured zone for thick coal seam top coal caving by CUI Ximin, CHE Yuhang, SUN Shuaihui, LI Peixian, SUN Hao, XU Zhihua, YUAN Debao, JIANG Jinbao, ZHAO Yuling, MALINOWSKA A

“…Based on the evolutionary law of the overburden and surface subsidence from subcritical to critical or supercritical mining, the Boltzmann function is introduced to express the relationship between the critical mining degree and the height of water-conducting fractured zone. …”
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Expanding the phenotypic and genetic spectrum of GTPBP3 deficiency: findings from nine Chinese pedigrees by Yaojun Xie, Keyi Li, Li Yang, Xiaofei Zeng, Zhehui Chen, Xue Ma, Luyi Zhang, Yuwei Zhou, Liqin Jin, Yanling Yang, Xiaoting Lou

“…Additionally, they displayed new symptoms such as eye problems like strabismus and heart issues related to valve function. Studies conducted on patient-derived cells provided evidence of reduced levels of GTPBP3 and impairment in mitochondrial energetic biogenesis. …”
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Secure Transmission for Energy Efficient Parallel Mixed FSO/RF System in Presence of Independent Eavesdroppers by Dipti R. Pattanayak, Vivek K. Dwivedi, Vikram Karwal, Abhijeet Upadhya, Hongjiang Lei, G. Singh

“…To investigate the security performance, the lower bound for the secrecy outage probability (SOP) and effective secrecy throughput (EST) have been obtained in terms of Meijer&#x2019;s G function. Thereafter, asymptotic expressions have been derived for the considered system and the numerical results have been verified by the Monte-Carlo simulation method. …”
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Low-density lipoprotein receptor-related protein 2 (LRP2) is required for lipid export in the midgut of the migratory locust, Locusta migratoria by Yiyan Zhao, Weimin Liu, Xiaoming Zhao, Zhitao Yu, Hongfang Guo, Yang Yang, Hans Merzendorfer, Kun Yan Zhu, Jianzhen Zhang

“…In the present study, we investigated the function of LRP2 in the migratory locust Locusta migratoria (LmLRP2). …”
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Technical note: How many models do we need to simulate hydrologic processes across large geographical domains? by W. J. M. Knoben, A. Raman, G. J. Gründemann, M. Kumar, A. Pietroniro, C. Shen, Y. Song, C. Thébault, K. van Werkhoven, A. W. Wood, A. W. Wood, M. P. Clark

“…We obtain similar conclusions for an objective function focused on low flows. These results suggest that, under the conditions typical of many current modelling studies, there is limited evidence that using a wide variety of different models leads to appreciable differences in simulation accuracy compared to using a smaller number of carefully chosen models.…”
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Targeted high-level production of chuangxinmycin and its halogenated derivatives with antitubercular activity by Xiongfang Zhao, Yuan Lu, Xintong Zhang, Xiumin Zhang, Yu Du, Xingli Han, Yuting Zhu, Wei Yu, Linzhuan Wu, Xingxing Li, Yuanyuan Shi, Tianyu Zhang, Bin Hong

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