Hypoxia-inducible factors: details create a picture. Part I. HIF-1 by G. A. Ignatenko, N. N. Bondarenko, S. V. Tumanova, T. S. Ignatenko, A. A. Kaluga, Ya. S. Valigun

“…The review presents a comparative analysis of scientific data on the structural and functional characteristics of subunits (HIF-1α and HIF-1β) of hypoxia-inducible transcription factor-1 (HIF-1). …”
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Relationship between enamel resistance and physical properties of saliva in drug-addicted patients by I. R. Fedun, V. M. Zubachyk, A. I. Furdychko, I. V. Han, M. P. Ilchyshyn

“…We examined the rate of salivation, which was calculated by the formula: Rs = V / T, pH of oral fluid using litmus test strips (Kelilong Instruments, China), structural and functional stability of tooth enamel by the express method TER-test (V. …”
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Distonia virtual por infarto talâmico posterolateral ventral: relato de caso Virtual dystonia due to a posteroventrolateral thalamic infarct: case report by Ricardo De Oliveira-Souza, Maria Elena de Lima Martins, Pedro Ângelo Andreiuolo, Andreia Rotmeister

“…Lifting the foot deprived S-I of tonic inputs conveyed by undamaged contact-pressure pathways, a functional effect promptly reversed by placing the foot back against the ground. …”
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Fostering positive affective exercise experiences and affect-related competencies for a physically active lifestyle: The FEEL Project – Results of the Pilot-Study by Martin Robert Bührer, Stephanie Rosenstiel, Gorden Sudeck, Julia Schmid

“…The control condition is a functional fitness program. At the SGS Conference, results from the pilot study which was done in Spring 2024 will be presented. …”
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High temporal-resolution transcriptome landscape reveals the biological process and regulatory genes of melanin deposition in breast muscle of Silkie chickens during embryonic deve... by Xinting Yang, Bowen Ma, Qingyu Zhao, Yaxiong Jia, Qingshi Meng, Yuchang Qin, Chaohua Tang, Junmin Zhang

“…Conclusions This study reveals the critical stage of melanin deposition in breast muscle during the embryonic development, and identified the biological processes and functional genes at each stage. This study provides novel insights into the biological process and regulatory mechanism of melanin deposition in skeletal muscle and provides a reference for breeding Silkies with high muscle melanin content.…”
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Shift work schedules alter immune cell regulation and accelerate cognitive impairment during aging by Karienn A. de Souza, Morgan Jackson, Justin Chen, Jocelin Reyes, Judy Muayad, Emma Tran, William Jackson, M. Karen Newell-Rogers, David J. Earnest

“…In conjunction with the effects of circadian dysregulation on cognition, shifted LD mice at middle age were distinguished by significant expansion of splenic B cells and B cell subtypes expressing the activation marker CD69 or inflammatory marker MHC Class II Invariant peptide (CLIP), differential increases in CLIP+, 41BB-Ligand+, and CD74 + B cells in the meningeal lymphatics, alterations in splenic T cell subtypes, and increased number and altered functional state of microglia in the dentate gyrus. …”
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Association mapping for root system architecture under varying levels of phosphorus application in Brassica juncea L. Czern & Coss by Priyanka Upadhyay, Mehak Gupta, Simarjeet Kaur Sra, Gurdeep Cheema, Virender K. Sardana, Rakesh Sharda, Nitika Sandhu, Javed Akhatar, Gurpreet Kaur

“…Identification of all Pi dose specific loci except one indicated high interactions between associated loci and Pi applications. Functional annotation of peak SNPs helped to predict 30 putative candidate genes for RSAr at varying Pi applications. …”
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A Monocyte-Driven Prognostic Model for Multiple Myeloma: Multi-Omics and Machine Learning Insights by Xie L, Gao M, Tan S, Zhou Y, Liu J, Wang L, Li X

“…Results indicated that low-risk patients are more likely to benefit from immunotherapy, while a high MGPS score reflects cellular functional impairment.Conclusion: Our findings reveal a complex interplay between immune cells and MM. …”
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INTERNATIONAL AND NATIONAL LEGAL MECHANISMS OF JUDICIAL LIABILITY IN THE CONDITIONS OF ECONOMIC GLOBALISATION OF MODERN SOCIETY by Konul Akhundova

“…The establishment of functional indicators of the judiciary has been undertaken, which are convergent in combination with economic indicators of the population's well-being, conditions for opening one's own business, ensuring financial and banking stability, GDP growth, the level of development of relevant sectors of industry and the economic sphere as a whole, etc. …”
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LncRNAs regulates cell death in osteosarcoma by Ping’an Zou, Zhiwei Tao, Zhengxu Yang, Tao Xiong, Zhi Deng, Qincan Chen, Li Niu

“…The objective of the current study was to identify if a functional lncRNA-based gene signature exists that regulates non-apoptotic RCD. …”
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CLINICAL SIGNIFICANCE OF DETERMINING THE LEVEL OF THE BRAIN NATRIURETIC PEPTIDE FOR THE DIAGNOSIS OF HEART FAILURE OF COMORBID PATIENTS WITH CORONARY HEART DISEASE AND THYROTOXICOS... by E. V. Pashchenko, A. I. Chesnikova, V. I. Kudinov, V. P. Terent’ev

“…All the patients were divided into 4 groups: the main one consisted of 25 patients with thyrotoxicosis, coronary heart disease (CHD) and II-III functional class (FC) chronic heart failure (CHF); the 1st comparison group consisted of 30 patients with coronary heart disease and II -III FC CHF, but without thyroid dysfunction; the 2nd comparison group consisted of 30 patients with thyrotoxicosis without CHD; the 3rd comparison group consisted of 26 patients with thyrotoxicosis and coronary heart disease, without CHF. …”
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Sustainable Development Clauses in the International Law of the Sea by A. N. Vylegzhanin, A. M. Korzhenyak

“…The research involves methods of legal construction, legal modeling, analysis and synthesis, systematic, struc­tural-functional, formal-logical, formal-legal, histori­cal and chronological methods.  …”
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FOOD AS A CONCEPT OF CULTURE AND INDIAN CODE IN JHUMPA LAHIRI`S WRITING by Olha V. Yalovenko

“…In the article we used the following methods: cultural and historical (defining the role and place of Lahiri`s writing in US literature of the twentieth century), historical and typological (determining the specifics of themes, motifs, images, story features of the writer`s works), functional (clarifying the features of Lahiri`s poetics), hermeneutic (interpretation of various aspects of the literary text), narratological analysis (specifics` analysis of Lahiri`s narrative manner), biographical (revealing the reflection of author`s personal experience in her writing), the principles of postcolonial and decolonial criticism (rethinking the problem of “otherness” in transculture discourse). …”
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Remodeling of articular cartilage and subchondral zone of the tibia in exo‑prosthetics of the limb by Tatyana A. Stupina, Andrey A. Emanov, Viktor P. Kuznetsov, Evgenij N. Ovchinnikov

“…Modern prostheses are becoming more high-tech, which requires deep understanding of the anatomical and functional features of the bone-joint system. Aim To identify features of structural reorganization of articular cartilage and subchondral zone of the tibia in lower leg prosthetics using an implant with calcium phosphate coating and an implant without additional coating. …”

Associations of steroid-specific antibodies and polymorphisms of cytokine genes with tumor proliferation in breast cancer patients by E. G. Polenok, L. A. Gordeeva, M. V. Kostyanko, A. V. Antonov, P. V. Bayramov, N. E. Verzhbitskaya, V. N. Zakharov, G. I. Kolpinskiy, A. N. Glushkov

“…In conclusion, immunomodulation of tumor proliferation by idiotypic and antiidiotypic antibodies specific to steroid hormones was associated with functional polymorphism rs1800796 of the IL6 gene.…”
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Chronic cerebral hypoperfusion induces venous dysfunction via EPAS1 regulation in mice by Vanessa Kristina Wazny, Aparna Mahadevan, Nhi Nguyen, Hannah Wee, Ashwati Vipin, Tammy Lam, Kai Yi Tay, Jia-Xiang See, Gurveen Sandhu, Yi Jin Leow, Giuseppe D’Agostino, Martin Graf, Aravind Sivakumar, Sichen Lin, Nguyen Cao Thien Phuc, James Xiao Yuan Chen, Sarah R. Langley, Lay Teng Ang, Kyle M. Loh, Nagaendran Kandiah, George J. Augustine, Christine Cheung

“…In human subjects, levels of damaged endothelial cells from venous vessels are correlated with white matter injury in the brain and poorer cognitive functions. Together, these findings indicate EPAS1 as a potential therapeutic target to restore cerebrovascular integrity and mitigate neuroinflammation.…”
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Temporal changes of neurobehavior in rats following varied blast magnitudes and screening of serum biomarkers in early stage of brain injury by Ning Ma, Hong Wang, Qing Lu, Jinren Liu, Xiaolin Fan, Liang Li, Qi Wang, Xiao Li, Boya Yu, Yuhao Zhang, Junhong Gao

“…Two co-expressed proteins were validated. Functional analysis revealed significant enrichment of 1121, 2096, and 1121 Gene Ontology (GO) items and 33, 47, and 26 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, indicating extensive molecular responses to overpressure in the early phase. …”
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Alveolar epithelial and vascular CXCR2 mediates transcytosis of CXCL1 in inflamed lungs by Katharina Thomas, Jan Rossaint, Nadine Ludwig, Sina Mersmann, Niklas Kötting, Julia Grenzheuser, Lena Schemmelmann, Marina Oguama, Andreas Margraf, Helena Block, Katharina Henke, Katharina Hellenthal, Valbona Mirakaj, Volker Gerke, Uwe Hansen, Karin Gäher, Miguel Engelhardt, Johannes Roth, Johannes Eble, Elin Hub, Antal Rot, Ronen Alon, Alexander Zarbock

“…Mechanistically, CXCR2-mediated CXCL1 endothelial and epithelial cell transcytosis requires the function of Bruton’s tyrosine kinase in these cells. …”
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Simplified two-compartment neuron with calcium dynamics capturing brain-state specific apical-amplification, -isolation and -drive by Elena Pastorelli, Alper Yegenoglu, Alper Yegenoglu, Nicole Kolodziej, Nicole Kolodziej, Nicole Kolodziej, Willem Wybo, Francesco Simula, Sandra Diaz-Pier, Johan Frederik Storm, Pier Stanislao Paolucci

“…A machine learning evolutionary algorithm, guided by a set of fitness functions, selected parameters defining neurons that express the desired apical dendritic mechanisms. …”
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Light-stimulated smart thermo-responsive constructs for enhanced wound healing: A streamlined command approach by Bingcheng Yi, Lei Yu, Yating Yang, Carlos F. Guimarães, Ruijie Xu, Thavasyappan Thambi, Boya Zhou, Qihui Zhou, Rui L. Reis

“…This, in turn, enhances fibroblast and endothelial cells ingrowth into the hydrogel, fostering cell functionalization and matrix remodeling. The top layer consists of poly(L-lactide-co-caprolactone) nanofibers functionalized with lysine-doped polydopamine and poly-l-lysine. …”
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