HPV E6/E7‐Induced Acetylation of a Peptide Encoded by a Long Non‐Coding RNA Inhibits Ferroptosis to Promote the Malignancy of Cervical Cancer by Xiaoyu Qi, Jing Zhou, Xinyue Wang, Yan Shen, Yuxun Cao, Liangzi Jiang, Miaomiao Shen, Haoran Zhang, Tianjiao Wang, Pengjun Wei, Ruoqi Xu, Yue Yang, Xiangya Ding, Cong Wang, Xuemei Jia, Qin Yan, Wan Li, Chun Lu

“…Abstract Although a fraction of functional peptides concealed within long non‐coding RNAs (lncRNAs) is identified, it remains unclear whether lncRNA‐encoded peptides are involved in the malignancy of cervical cancer (CC). …”
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Cytokine production by the bioptates of invasive non-specific breast carcinoma as a criterion for the use of acetylamide form of synthetic HLDF-6 peptide for differentiation therap... by E. D. Mangazeeva, A. A. Studenikina, E. S. Michailova, D. V. Morozov, S. L. Ryzhikova, Yu. G. Druzhinina, A. V. Proskura, A. P. Bogachuk, V. M. Lipkin, A. I. Autenshlyus

“…The effect of this peptide may be associated with altered functional activity of the tumour. The aim of our study was to investigate the effect of acetyl-amide form of synthetic HLDF-6 peptide on cytokine production by bioptates of invasive non-specific breast carcinoma. …”
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A critical review on phasor measurement units installation planning and application in smart grid environment by Vivekananda Pattanaik, Binaya Kumar Malika, Subhasis Panda, Pravat Kumar Rout, Binod Kumar Sahu, Indu Sekhar Samanta, Mohit Bajaj, Vojtech Blazek, Lukas Prokop

“…Also, the problem formulation for the PMUs placement is expressed, giving importance to the objective function, constraints, variables, and assessment index reflecting the optimality in placement. …”
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Evaluation of transcriptomic changes after photobiomodulation in spinal cord injury by Andrew R. Stevens, Mohammed Hadis, Hannah Alldrit, Michael R. Milward, Valentina Di Pietro, Deena M. A. Gendoo, Antonio Belli, William Palin, David J. Davies, Zubair Ahmed

“…Photobiomodulation (PBM) is a promising therapy which has proven effective at restoring lost function after SCI in pre-clinical models. However, the precise mechanism of action is yet to be determined. …”
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Inhibitory Mechanisms of Vine Tea Extract and Dihydromyricetin Against <i>Escherichia coli</i>: A Multidimensional Analysis from Cell Membrane to Protein Synthesis by Wei Ma, Haiyun Liang, Keke He, Ting Li, Qiaoni Hui, Yao Zhang, Yuxuan Dong, Yan Jia, Liya Song

“…Additionally, VTE disrupts various secondary metabolic pathways, while DMY interferes with <i>E. coli</i> ribosome assembly and function, and disrupts cell membrane lipid homeostasis by interfering with fatty acid metabolism. …”
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The Renin–Angiotensin System Modulates SARS-CoV-2 Entry via ACE2 Receptor by Sophia Gagliardi, Tristan Hotchkin, Hasset Tibebe, Grace Hillmer, Dacia Marquez, Coco Izumi, Jason Chang, Alexander Diggs, Jiro Ezaki, Yuichiro J. Suzuki, Taisuke Izumi

“…The renin–angiotensin system (RAS) plays a central role in cardiovascular regulation and has gained prominence in the pathogenesis of Coronavirus Disease 2019 (COVID-19) due to the critical function of angiotensin-converting enzyme 2 (ACE2) as the entry receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). …”
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SNRPB2: a prognostic biomarker and oncogenic driver in esophageal cancer via β-catenin/c-Myc signaling by Jiaqian Bao, Jiaqian Bao, Xiong Tian, Xiong Tian, Yixiao Pan, Yixiao Pan, Yiqing Guo, Yiqing Guo, Zhenyu Yang, Zhenyu Yang, Meifu Gan, Meifu Gan, Jingmin Zheng, Jingmin Zheng

“…The biological functions of SNRPB2 were assessed in vitro cell assay and in vivo tumor models. …”
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Impact of the COVID-19 Pandemic and the 2021 National Institute for Health and Care Excellence Guidelines on Public Perspectives Toward Myalgic Encephalomyelitis/Chronic Fatigue Sy... by Iliya Khakban, Shagun Jain, Joseph Gallab, Blossom Dharmaraj, Fangwen Zhou, Cynthia Lokker, Wael Abdelkader, Dena Zeraatkar, Jason W Busse

“… BackgroundMyalgic encephalomyelitis (ME), also referred to as chronic fatigue syndrome (CFS), is a complex illness that typically presents with disabling fatigue and cognitive and functional impairment. The etiology and management of ME/CFS remain contentious and patients often describe their experiences through social media. …”
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FlyPhoneDB2: A computational framework for analyzing cell-cell communication in Drosophila scRNA-seq data integrating AlphaFold-multimer predictions by Mujeeb Qadiri, Ying Liu, Ah-Ram Kim, Myeonghoon Han, Eric Zhou, Austin Veal, Tzu-Chiao Lu, Hongjie Li, Yanhui Hu, Norbert Perrimon

“…In addition, the algorithm has been optimized for improved performance and more effective noise filtering. New functionalities have also been introduced, such as the addition of downstream reporter genes to evaluate pathway activity, multi-sample CCC comparison, and enhanced visualizations summarizing communication at a network level.We demonstrate the utility of FlyPhoneDB2 by analyzing whole-body single-nuclei RNA-seq datasets from flies with gut tumors induced by the Yorkie oncogene. …”
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Genome-Wide Characterization of the <i>ANN</i> Gene Family in <i>Corydalis saxicola</i> Bunting and the Role of CsANN1 in Dehydrocavidine Biosynthesis by Han Liu, Jing Wang, Zhaodi Wen, Mei Qin, Ying Lu, Lirong Huang, Xialian Ou, Liang Kang, Cui Li, Ming Lei, Zhanjiang Zhang

“…This study sheds light on the profiles and functions of the <i>CsANN</i> gene family and paves the way for unraveling the molecular mechanism of BIA accumulation, which is regulated by Ca²⁺ through CsANNs.…”
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Absent in melanoma 2: a potent suppressor of retinal pigment epithelial-mesenchymal transition and experimental proliferative vitreoretinopathy by Yu Chen, Mingyuan Jiang, Liping Li, Shanshan Yang, Zuimeng Liu, Shiwen Lin, Wanxiao Wang, Jinyang Li, Feng Chen, Qiang Hou, Xiaoyin Ma, Ling Hou

“…The present study demonstrated that AIM2 functions as a potent suppressor of RPE cell proliferation and EMT to maintain retinal homeostasis. …”
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Differentiation of Stem Cells from Human Exfoliated Deciduous Teeth into Retinal Photoreceptor-Like Cells and Their Sustainability In Vivo by Xiaoxia Li, Jing Xie, Yue Zhai, Tengjiaozi Fang, Nanquan Rao, Shuang Hu, Liping Yang, Yuming Zhao, Yixiang Wang, Lihong Ge

“…Many studies have reported that mesenchymal stem cell transplantation can sustain retinal structure and prolong retinal functions based on two mechanisms. One is cell replacement, and the other is the paracrine action of stem cells. …”
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Clinical Significance of <i>LINC00261</i> in the Pathogenesis of Pancreatic, Colorectal, Hepatocellular, and Gallbladder Cancer by Sanjana Bana, Sia Daffara, Aastha Dagar, Ashutosh Kumar Tiwari, Kanupriya Medhi, Sagarika Mukherjee, Vivek Uttam, Md Rizwan Ansari, Hardeep Singh Tuli, Vikas Yadav, Aklank Jain

“…Our comprehensive literature analysis revealed that <i>LINC00261</i> functions as a tumor suppressor, and its reduced expression is associated with larger tumor size, advanced tumor-node-metastasis (TNM) stages, lymphatic metastasis, and poorer overall survival rates. …”
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Selective arm-usage of pre-miR-1307 dysregulates angiogenesis and affects breast cancer aggressiveness by Oyku Ece Sumer, Korbinian Schelzig, Janine Jung, Xiaoya Li, Janina Moros, Luisa Schwarzmüller, Ezgi Sen, Sabine Karolus, Angelika Wörner, Verônica Rodrigues de Melo Costa, Nishanth Belugali Nataraj, Efstathios-Iason Vlachavas, Clarissa Gerhäuser, Karin Müller-Decker, Dominic Helm, Yosef Yarden, Birgitta Elisabeth Michels, Cindy Körner

“…A pre-miRNA, such as pre-miR-1307, gives rise to several mature miRNA molecules with distinct functions. However, the impact of global deregulation of pre-miR-1307 and its individual mature miRNAs in breast cancer has not been investigated in breast cancer, yet. …”
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Single-cell analyses of intestinal epithelium reveal the dysregulation of gut immune microenvironment in systemic lupus erythematosus by Qiaolin Wang, Yutong Wu, Lianlian Ouyang, Xiaoli Min, Meiling Zheng, Lingyu Gao, Xiaoyun Chen, Zhi Hu, Shuang Yang, Wenjuan Jiang, Sujie Jia, Qianjin Lu, Ming Zhao

“…Additionally, subsets of CD8 + IELs exhibiting significantly enhanced effector functions were found to be markedly enriched in Lpr mice. …”
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HIV-1 Vpu interacts with RBM10 to promote HIV-1 infection by Boye Li, Yanzhe Hao, Xianbin Meng, Xiaoming Wang, Qingyan Li, Runqing Jia, Yishu Yang, Jinning Yang, Boyang Yu, Tian Chen, Wenmei Zhang, Xiaoguang Zhang, Xiayan Wang, Qin Hu

“…ABSTRACT Viral protein U (Vpu), an accessory protein of HIV-1, functions by antagonizing or hijacking various host factors to allow the virus to evade host immune surveillance and facilitate viral release. …”
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The m6A modification of LINC01133 suppresses ER+ breast cancer progression by modulating IGF2BP2 protein stability via a ubiquitination-dependent mechanism by Mai-dong Li, Mai-dong Li, Ben-jie Shan, Lei Wang, Shuang Gao, Li Hao, Hai-yang Yu, Yue-yin Pan, Yue-yin Pan

“…LINC01133 exhibits opposing expressing patterns across different breast cancer subtypes, yet its roles and mechanisms in ER+ breast cancer remain a loaded question.MethodsThe expression of LINC01133 was initially assessed utilizing a public dataset TCGA and subsequently validated within clinical samples through RT-qPCR and in situ hybridization (ISH). …”
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In vitro vascular differentiation system efficiently produces natural killer cells for cancer immunotherapies by Yekaterina Galat, Yuchen Du, Mariana Perepitchka, Xiao-Nan Li, Irina V Balyasnikova, William T Tse, Svetlana Dambaeva, Sylvia Schneiderman, Philip M Iannaccone, Oren Becher, Douglas K Graham, Vasiliy Galat

“…NK cytotoxicity was validated using in vitro and in vitro K562 assays and further corroborated on lymphoma, diffuse intrinsic pontine glioma (DIPG), and GBM cell lines in vitro.Results HPCs demonstrated engraftment in peripheral blood samples, and hPSC-NKs showcased morphology and functionality akin to same donor peripheral blood NKs (PB-NKs). …”
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Fatty acid metabolism of granulose cells and follicular fluid and their associations with embryo quality in normal-weight women with PCOS by Ye Tian, Aiyuan Wang, Fang Li, Siyu Wang, Jie Shang, Kai Zhang, Xiaohong Bai

“…Functional enrichment analysis and metabolism score calculation revealed that fatty acid metabolism pathways, especially the biosynthesis of unsaturated fatty acids, were downregulated. …”
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Component Composition and Antimicrobial Activity of CO2 Extract of Portulaca oleracea, Growing in the Territory of Kazakhstan by Meruyert I. Tleubayeva, Ubaidilla M. Datkhayev, Mereke Alimzhanova, Margarita Yu Ishmuratova, Nadezhda V. Korotetskaya, Raisa M. Abdullabekova, Elena V. Flisyuk, Nadezhda G. Gemejiyeva

“…The use of carbon dioxide extraction (further CO2 extract) is a promising direction of obtaining total medicinal substances containing biologically active substances, from fractions of volatile esters of various composition and functional purpose until a fraction of fatty acids and fat-soluble vitamins. …”
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