Clinical and functional characterization of p.Lys322stop variant in the SERPINC1 gene causing severe thrombophilia by Haiyue Zhang, Xinyang Yue, Tenglong Dai, Jun Wu

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Tazul Tajuddin’s Opera Serikandi Nusantara: The Diminution of Functional Tonality and Its Symbolic Role from an Esthesis Perspective by Mohd Adam Masumi, Tazul Izan Tajuddin

“…It conjures up a sense of departure from the conventions of functional tonality in which the musical ideas are organised through the contemporary musical language and imaginative use of instrumental timbre and extended techniques. …”
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Scorpion (Hottentotta tamulus) venom pre-exposure delays functional recovery in mice following peripheral nerve injury. by Abbas Khan, Chand Raza, Muhammad Tariq Zahid, Hafiz Faseeh Ur Rehman, Shahzad Sharif, Khajid Ullah Khan

“…Of note, venom pre-exposure delays and compromises the sensori-motor functional recovery in STE and MTE mice following standard sciatic nerve crush injury. …”
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Semantics and Functioning of Color Terminology in Autobiographies of Artists from Late 19th to Early 20th Century by M. M. Sandalova, L. V. Kalinina

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Human hair follicle-derived mesenchymal stem cells improve ovarian function in cyclophosphamide-induced POF mice by Jinhua Mo, Hong Hu, Pengdong Li, Yang Ye, Wanle Chen, Lei Chen, Jing Qiao, Xiaoying Zhao, Qiuxia Yan, Cairong Chen

“…Abstract Introduction Mesenchymal stem cell (MSCs) of different tissue origins have become a new option for the treatment of premature ovarian failure (POF) as they can recovery the ovarian function. However, there were rarely researches about human hair follicle-derived mesenchymal stem cells (HF-MSCs) in POF. …”
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A Key Role for NF-κB Transcription Factor c-Rel in T-Lymphocyte-Differentiation and Effector Functions by Alexander Visekruna, Anton Volkov, Ulrich Steinhoff

“…Additionally, c-Rel-dependent IL-12 and IL-23 transcription by macrophages and dendritic cells is crucial for T-cell differentiation and effector functions. Accordingly, c-Rel expression in T cells and antigen-presenting cells (APCs) controls a delicate balance between tolerance and immunity. …”
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AMH regulates granulosa cell function via ESR2/ p38-MAPK signaling pathway in sheep by Hui Xu, Yu Cai, Hua Yang, Chong Zhang, Wanru Liu, Binru Zhao, Feng Wang, Yanli Zhang

“…These findings demonstrate AMH regulates GCs function through multiple pathways, offering insights into sheep fertility and potential targets to enhance reproductive efficiency.…”
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ON THE ISSUE OF CENSORSHIP: THE CONCEPT, THE SYSTEMATIC APPROACH TO THE STUDY, HISTORIOGRAPHY OF THE FUNCTIONING OF CENSORSHIP ON THE TERRITORY OF BELARUS IN THE PERIOD OF 1905 –... by Tsumarava Elena Petrovna

“…The interde-pendence of public mood and actions with changes in censorship, the influence of the internal and external environment found special expression in these periods. The study revealed that there has been no comprehensive study of censorship on the territory of Belarus in 1905 – 1917 either in native or foreign historiography; therefore there is a need for a detailed development of the functioning of the censorship apparatus, the study of the practice of censoring publications in the period under study.…”
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Insights into the Function of the Unstructured N-Terminal Domain of Proteins 4.1R and 4.1G in Erythropoiesis by Wataru Nunomura, Philippe Gascard, Yuichi Takakuwa

“…One goal in the field is to better understand the complex regulation of cell type and isoform-specific expression of 4.1 proteins. To start answering these questions, we are studying in depth the important functions of 4.1 proteins in the organization and function of the membrane skeleton in erythrocytes. …”
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IL-27 regulates the number, function and cytotoxic program of antiviral CD4 T cells and promotes cytomegalovirus persistence. by Ellen J Wehrens, Kurt A Wong, Ankan Gupta, Ayesha Khan, Chris A Benedict, Elina I Zuniga

“…Together, these data show that IL-27 regulates the number and effector functions of MCMV-specific CD4 T cells and could be targeted to enhance control of persistent/latent infection.…”
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Cognitive Dysfunction in Patients Treated with Androgen Deprivation Therapy: A Multimodality Functional Imaging Study to Evaluate Neuroinflammation by Azeem Saleem, Syed Imran Ali Shah, Stephen A. Mangar, Christopher Coello, Matthew B. Wall, Gaia Rizzo, Terry Jones, Patricia M. Price

“…However, we speculate that the strong correlation between TSPO uptake and BOLD-fMRI activation in brain regions involved in memory and known to have high androgen-receptor expression mediating plasticity (hippocampus and amygdala) might reflect inflammatory effects of ADT with compensatory upregulated/increased synaptic functions. …”
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Poneratoxin as a key tool for investigating the relationship between sodium channel hypersensitivity and impaired nerve cell function by Zirui Lü, Xiandong Dai, Jianjie Xu, Mu Zhu, Bo Chen, Yongbiao Guo, Zhenhua Gao, Fanhua Meng

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Underground guardians: how collagen and chitin amendments shape soil microbiome structure and function for Meloidogyne enterolobii control by Josephine M. Pasche, Roshni Sawlani, Victor Hugo Buttrós, Johan Desaeger, Karen A. Garrett, Samuel J. Martins

“…This study evaluated the impact of collagen and chitin soil amendments on soil microbial composition and function (fungal and bacterial communities) and their effects on tomato plant health and M. enterolobii infection under standard (5000 eggs plant−1) and high (50,000 eggs plant−1) inoculum pressure. …”
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The nuclear effector of Wnt-signaling, Tcf1, functions as a T-cell-specific tumor suppressor for development of lymphomas. by Machteld M Tiemessen, Miranda R M Baert, Tom Schonewille, Martijn H Brugman, Farbod Famili, Daniela C F Salvatori, Jules P P Meijerink, Ugur Ozbek, Hans Clevers, Jacques J M van Dongen, Frank J T Staal

“…Tcf1 therefore functions as a T-cell-specific tumor suppressor gene, besides its established role as a Wnt responsive transcription factor. …”
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The Role and Functions of City Parks in the Adaptation Process of Refugees to the City: The Case of Ulubey Şehit Ömer Karaosmanoğlu Park by Seynan Güler, Dicle Oğuz, Başak Yurtseven

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A mixture of ginger phenolic compounds enhances mitochondrial function, activates AMPK, and reduces lipid accumulation in adipocytes. by María Elizabeth Preciado-Ortiz, Berenice Pérez-Jiménez, Paulina Barrera-Gómez, Juan José Rivera-Valdés, Joshua Ayork Acevedo-Carabantes, Sarai Vásquez-Reyes, Armando R Tovar, Nimbe Torres, Ivan Torre-Villalvazo, Erika Martínez-López

“…Mitochondrial abundance and activity in adipocytes are critical for adequate adipose tissue function and whole-body energy homeostasis. Mitochondrial dysfunction in adipocytes impairs lipid metabolism, insulin sensitivity, and thermogenesis, leading to metabolic diseases. …”
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Structural insights into a highly flexible zinc finger module unravel INSM1 function in transcription regulation by Heng Zhou, Xiaoling He, Yue Xiong, Yixuan Gong, Yuanyuan Zhang, Shuangli Li, Rui Hu, Ying Li, Xu Zhang, Xin Zhou, Jiang Zhu, Yunhuang Yang, Maili Liu

“…Instead, INSM1 collaborates with CTCF to target genome loci having the GGGG-contained element and regulate the expression of adjacent genes. This study defines a functional mode of INSM1 by cooperating with diverse DNA-binding proteins for targeting specific genome loci in transcription regulation, and provides structural information for designing INSM1-related therapeutic drugs and diagnostic probes.…”
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Genome-wide identification of sugarcane HAT gene family and functional analysis of ScHAT1 in stress response by Shijiang Cui, Shiwei Yang, Ping Zhao, Shoujian Zang, Zhenxiang Li, Peixia Lin, Wanying Zhao, Yuanyuan Zhang, Dongjiao Wang, Youxiong Que, Qibin Wu

“…Histone acetyltransferases (HATs) are key regulators in plant stress responses, yet their functions and mechanisms remain largely unexplored in sugarcane. …”
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Enhancing Mitochondrial Function Through Pharmacological Modification: A Novel Approach to Mitochondrial Transplantation in a Sepsis Model by Bomi Kim, Yun-Seok Kim, Kyuseok Kim

“…<b>Methods:</b> We examined various mitochondrial-targeting drugs (formoterol, metformin, CoQ10, pioglitazone, fenofibrate, and elamipretide) to improve mitochondrial function prior to transplantation. Mitochondrial function was assessed by measuring the oxygen consumption rate (OCR) and analyzing the expression of genes related to mitochondrial biogenesis. …”
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In Vivo Transplantation of Enteric Neural Crest Cells into Mouse Gut; Engraftment, Functional Integration and Long-Term Safety. by Julie E Cooper, Conor J McCann, Dipa Natarajan, Shanas Choudhury, Werend Boesmans, Jean-Marie Delalande, Pieter Vanden Berghe, Alan J Burns, Nikhil Thapar

“…Intestines were then assessed for ENCC integration and differentiation using immunohistochemistry, cell function using calcium imaging, and long-term safety using PCR to detect off-target YFP expression.…”
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