Influence of environmental exposures on T follicular helper cell function and implications on immunity: a comparison of Bangladeshi and American children by Dana M. Van Fossen, Hyunjae Cho, Lisa E. Wagar, Jennie Z. Ma, Julie Parsonnet, Rashidul Haque, Mark M. Davis, William A. Petri

“…ABSTRACT T follicular helper (Tfh) cells are crucial for B cell activation and subsequent antibody production. This functionality is influenced by surface markers such as CD40L, a costimulatory factor which promotes B cell activation, and CD57, which is a well-known marker of senescence. …”
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Impact of Lysine to Methionine Ratios on Antioxidant Capacity and Immune Function in the Rumen of Tibetan Sheep: An RNA‐Seq Analysis by Fengshuo Zhang, Quyangangmao Su, Zhanhong Gao, Zhenling Wu, Qiurong Ji, Tingli He, Kaina Zhu, Xuan Chen, Yu Zhang, Shengzhen Hou, Linsheng Gui

“…COL16A1 and KCNK5 were highly expressed in the protein digestion and absorption pathway, maintaining the structural integrity and function of the rumen epithelium. …”
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Novel functional eQTL-SNPs associated with susceptibility to occupational pulmonary fibrosis: A multi-stage study by Rui Zhao, Xiaobo Tao, Wendi Zhang, Siqi Li, Shenxuan Zhou, Anhui Ning, Zhenyu Li, Minjie Chu, Wei Wang, Junhong Jiang

“…Methods: We first integrated the genome-wide association studies (GWASs) of IPF and silicosis to obtain the shared SNPs. Following this, functional expression quantitative trait locus (eQTL)-SNPs were identified by the GTEx database. …”
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Effects of cardamonin on the growth performance, intestinal barrier function and intestinal microbiota of Danzhou chickens under heat stress by Haoran Jiang, Liguang Shi, Tanjie Deng, Guanyu Hou, Wenjuan Xun

“…ABSTRACT: The aim of this study was to investigate the effects of cardamonin (CDN) on the growth performance, intestinal mucosal barrier function and intestinal microbiota of Danzhou chickens under heat stress. …”
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PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP by Jiongke Wang, Yujie Shi, Ying Wang, Yingqiang Shen, Huan Liu, Silu Sun, Yimei Wang, Xikun Zhou, Yu Zhou, Xin Zeng, Jing Li, Qianming Chen

“…Notably, we found that PA28γ enhances C1QBP protein stability in OSCC. Functionally, PA28γ and C1QBP co-localized in mitochondria, promoting fusion (via upregulation of OPA1, MFN1/2), respiratory complex expression, oxidative phosphorylation (OXPHOS), ATP production, and ROS generation. …”
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The G protein modifier KCTD5 tunes the decoding of neuromodulatory signals necessary for motor function in striatal neurons. by Douglas C Sloan, Yini Liao, Forest Ray, Brian S Muntean

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Cigarette Smoke Exposure Leads to Organic and Mineral Bone Component Changes: The Importance of Rho Kinase Function in These Events by Alex Ferreira da Silva, Franciele Jesus Lima, Alyne Riani Moreira, Cintia do Nascimento Silva, Ivone Braga de Oliveira, Alexandra Fernandes Callera, Ana Luiza Porfirio, Luan Henrique Vasconcelos Alves, Iolanda de Fátima Lopes Calvo Tibério, Ana Paula Pereira Velosa, Vanda Jorgetti, Walcy Rosolia Teodoro, Fernanda Degobbi Tibério Quirino Dos Santos Lopes

“…Aberrant Rho-associated kinase function could be associated with increased bone fragility. …”
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Identification and Functional Analysis of Three <i>NlCstF</i> Genes in <i>Nilaparvata lugens</i> by Shengli Jing, Feifei Wang, Aobo Ren, Fang Zheng, Bingbing Yu, Jingang Xu, Yali Liu, Jing Yang, Ruixian Chen, Wei Zeng, Yimei Zhang, Danxia Ke, Xiantao Ma, Hengmin Tang, Qingsong Liu, Bin Yu

“…In mammals, this complex includes CstF50, CstF64, and CstF77, named according to their molecular weights, and these proteins are conserved across many organisms. However, the functional roles of the three CstF genes (<i>NlCstF50</i>, <i>NlCstF64</i>, and <i>NlCstF77</i>) in <i>Nilaparvata lugens</i>, a major rice pest, have not been fully explored. …”
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A functional complementation of a cotton MIZU-KUSSEI1 homolog in the hydrotropism response of Arabidopsis thaliana roots by Su-Hwan Kwak, Wonkeun John Park

“…To investigate the molecular mechanism of hydrotropism in cotton, we examined the function of GhMIZ1, the closest homolog of Arabidopsis thaliana MIZ1. …”
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Polystyrene microplastics impair the function of human retinal microvascular endothelial cells and pericytes and increase vascular permeability in vitro by Jang-Hyuk Yun

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Specific features of the establishment of puberty in girls with type 1 diabetes mellitus and related disturbances of menstrualand ovarian functions by Olga Rafael'evna Grigoryan, Anna Alexandrovna Okhotnikova, Elena Nikolaevna Andreeva

“…Type 1 diabetes mellitus (DM1) exerts negative impact on the formation and functioning of the reproductive system in young girls. …”
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Chronic hypoxia has differential effects on constitutive and antigen-stimulated immune function in Atlantic salmon (Salmo salar) by Isis Rojas, Mariana M. M. de Mello, Fábio S. Zanuzzo, Rebeccah M. Sandrelli, Ellen de Fátima C. Peroni, Jennifer R. Hall, Matthew L. Rise, Elisabeth C. Urbinati, Anthony K. Gamperl

“…., at Time 0, to assess constitutive immune function), and after they were intraperitoneally injected with PBS (phosphate buffered saline) or formalin-killed Aeromonas salmonicida. …”
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Exploring the differential functions of circulating follicular helper T and peripheral helper T cells in rheumatoid arthritis based on metabolism patterns by Ziran Bai, Ziran Bai, Siwen Yang, Jinyi Ren, Cheng Zhang, Xianmei Chen, Huina Huang, Guan Wang, Yawei Tang, Jingjing Qi, Xia Li

“…The frequency, transcription factors, functional molecules, cellular senescence, glycolytic activity and mitochondrial ROS (mtROS) of cTfh and Tph cells were assessed. …”
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Network-based elucidation of human disease similarities reveals common functional modules enriched for pluripotent drug targets. by Silpa Suthram, Joel T Dudley, Annie P Chiang, Rong Chen, Trevor J Hastie, Atul J Butte

“…We identified 4,620 functional modules in the human protein network and provided a quantitative metric to record their responses in 54 diseases leading to 138 significant similarities between diseases. …”
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Inhibition of the Renin–Angiotensin System Improves Hemodynamic Function of the Diabetic Rat Heart by Restoring Intracellular Calcium Regulation by Krisztina Anna Paulik, Tamás Ivanics, Gábor A. Dunay, Ágnes Fülöp, Margit Kerék, Klára Takács, Zoltán Benyó, Zsuzsanna Miklós

“…In T1D, rats were treated with Enalapril (Ena) or Losartan (Los) for six weeks, whereas T2D animals received high-dose (HD) or low-dose (LD) Ena for 8 weeks. Heart function was assessed via echocardiography, Ca²⁺_i transients by Indo-1 fluorometry in Langendorff-perfused hearts, and key Ca²⁺_i cycling proteins by Western blot. …”
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Role of the heterogenous structure of ZnO/MnFeO3 in enhancing Bi-functional electrocatalyst for alkaline water electrolysis by Malavika Sadanandan, Tushar Chauhan, Krishna Kanta Haldar

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Functional Role of Resveratrol in Inducing Apoptosis in Breast Cancer Subtypes via Inhibition of Intracellular Fatty Acid Synthase by Ping Li, Yan Liang, Xiaofeng Ma

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Workflow for a Functional Assay of Candidate Effectors From Phytopathogens Using a TMV-GFP-based System by Peng Cao, Haotian Shi, Jialan Chen, Langjun Cui, Meixiang Zhang, Yuyan An

“…This system enables the rapid identification of effectors that interfere with plant immunity (both activation and suppression). The biological function of these effectors can be easily evaluated within six days by observing the GFP fluorescence signal using a UV lamp. …”
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Molecular crosstalk between insulin‐like growth factors and follicle‐stimulating hormone in the regulation of granulosa cell function by Emily Hayes, Nicola Winston, Carlos Stocco

“…New evidence suggests that FSH and IGF signaling pathways intersect at several levels to regulate gene expression and GC function. Conclusion FSH and locally produced IGFs form a positive feedback loop essential for preovulatory follicle formation in all species. …”
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RETRACTED: IAV Antagonizes Host Innate Immunity by Weakening the LncRNA-LRIR2-Mediated Antiviral Functions by Na Chen, Baoge Zhang

“…In addition, the antiviral function of LRIR2 is mainly dependent on the stem-loop structures of 1–118 nt and 575–683 nt. …”
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